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Kano Junko

Affiliation
Faculty of Medicine
Official title
Assistant Professor
Email
 
Phone
029-853-3350
Fax
029-853-3350
Research fields
Experimental pathology
Research keywords
carcinogenesis
hepatic stem cell
hepatic differentiation
Research projects
肝分化・肝再生におけるdickkopf3の作用機序の解明2009 -- 2011Japan Society of for the Promotion of Science/基盤研究(C)4380000
胎児抗原に着目した腫瘍関連蛋白の網羅的探索と診断・治療への応用2008 -- 2009Japan Society of for the Promotion of Science/挑戦的萌芽研究
肝幹細胞特徴的発現遺伝子の機能解析と慢性肝炎・肝硬変診断への応用 2005 -- 2006Japan Society of for the Promotion of Science/基盤研究(C)4130000
成体肝幹様細胞の分化特異的発現遺伝子のcDNA Subtraction法での解析2003 -- 2004Japan Society of for the Promotion of Science/基盤研究(C)3600000
Career history
1996-12 -- 1998-03産業技術融合領域研究所 特別技術補助職員
2000-04 -- 2001-03筑波大学 基礎医学系 リサーチアシスタント
2001-06 -- 2004-03筑波大学 基礎医学系 講師
2001-09 -- 2002-03茨城県立医療大学 非常勤講師
2003-01 -- 2004-03筑波大学 大学院人間総合科学研究科分子情報・生体統御医学専攻 講師
2004-04 -- (current)国立大学法人筑波大学 大学院人間総合科学研究科分子情報・生体統御医学専攻 講師
Academic background
-- 1980Ochanomizu University 家政学部 食物学科Graduated
-- 1983Ibaraki University Graduate School, Division of Agriculture 農芸化学専攻Completed
-- 2001University of Tsukuba Graduate School, Division of Medicine 形態系Completed
Degree
医学博士University of Tsukuba
農学修士Ibaraki University
Academic societies
-- (current)肝細胞研究会
-- (current)The Japanese Cancer Association
-- (current)THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
-- (current)THE JAPANESE SOCIETY OF PATHOLOGY
Articles
  • 人工肝に利用する細胞—多孔質基材を用いた不死化細胞の三次元組織化
    加野 准子; 常盤孝義
    組織培養工学/23/pp.42-43, 1997
  • 多孔質材料を用いたCHO-K1細胞の無血清培養
    加野准子; 常盤孝義; 児玉亮; 村松外志張
    生体材料/15(2)/pp.55-62, 1997
  • Stratifin accelerates progression of lung adenocarcinoma at an early stage.
    Shiba Aya; Kim YungJun; Shiozawa Toshihiro; Iyama Shinji;...
    MOLECULAR CANCER/14(142), 2015-07
  • Stratifin accelerates progression of lung adenocarcinoma at an early stage
    Shiba-Ishii A; YunJung Kim; Toshihiro Shiozawa; Shinji Iy...
    MOLECULAR CANCER/14(1)/pp.142-142, 2015-07
  • STRATIFIN EXPRESSED IN EARLY INVASIVE LUNG ADENOCARCINOMA FUNCTIONALLY ENHANCES TUMOR PROGRESSION AND DOWN-REGULATES SCFF-BW7 UBIQUITIN LIGASE ACTIVITY
    Shiba Aya; Iguchi Yukari; Morishita Yukio; Shiozawa Toshi...
    JOURNAL OF THORACIC ONCOLOGY/8(2)/pp.S750-S750, 2013-11
  • PRKAR1A overexpression is associated with increased ECPKA autoantibody in liver fluke-associated cholangiocarcinoma: application for assessment of the risk group.
    Kano Junko; 1. Watcharin Loilome Sasithorn Yooyuen Nisana...
    Tumor Biology/33(6)/pp.2289-2298, 2012-12
  • Moesin overexpression is a unique biomarker of adenomyosis
    Ohara Rena; Michikami Hiroo; Nakamura Yuko; Sakata Akiko;...
    Pathol Int/64(3)/pp.115-122, 2014-03
  • Increased cytoplasmic S100A6 expression is associated with pulmonary adenocarcinoma progression.
    Shiba Aya; Suzuki Meguri; Satomi Kaisi; Kobayashi Hiromi;...
    Pathology International/59/pp.623-630, 2009-09
  • High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma.
    Shiba Aya; Kano Junko; Morishita Yukio; Sato Yukio; Minam...
    International Journal of Cancer/129(10)/pp.2445-2453, 2011-11
  • Binding of lactoferrin to IGBP1 triggers apoptosis in a lung adenocarcinoma cell line.
    Li Dongping; Sakashita Shingo; Kano Junko; Shiba Aya; Sat...
    Anticancer research/31/pp.529-534, 2011-02
  • Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis.
    Tachibana Keisei; Minami Yuko; Shiba Aya; Junko Kano;...
    Lung cancer/75(2)/pp.181-188, 2012-02
  • IGFBP-1 is expressed specifically in ovarian clear cell adenocarcinoma.
    Sugita Shintaro; Morishita Yukio; Kano Junko; Furuya Shui...
    Histopathology/58(5)/pp.729-738, 2011-04
  • Expression of HNFs and C/EBP alpha is correlated with immunocytochemical differentiation of cell lines derived from human hepatocellular carcinomas, hepatoblastomas and immortalized hepatocytes.
    Ishiyama Tadashi; Kano Junko; Minami Yuko; Iijima Tatsuo;...
    Cancer Sci./94(9)/pp.757-763, 2003-09
  • Expression of HNFs and C/EBPα is correlated with immunocytochemical differentiation of cell lines derived from human hepatocellular carcinomas, hepatoblastomas and immortalized hepatocytes.
    Ishiyama T; Kano J; Minami Y; Iijima T; Morishita Y; Nogu...
    Cancer Sci/94/pp.757-763, 2003-01
  • 3-indolylacetic acid-dependent antibacterial activity in rice plant
    Uesugi Y; Kano J; Kodama O; Akatsuka T.
    Ann. Rhytopathol. Soc J./50(11)/pp.67 -71, 1984-01
  • Formation of non-spheroidal aggregates by adult rat hepatocytes on polyacrilamide coated surface
    Tokiwa T; Kano J; Meng X; Bahulekar R; Kodama M.
    Biotech. Tech./10(11)/pp.845-848, 1996-11
  • Morphology and function of rat hepatocytes cultured on expanded polytetrafluoroethylene surface
    Tokiwa T; Kano J; Meng X; Kodama M; Matsumura T.
    Pro. JAACT/19/pp.291-293, 1996-01
  • Immobilization of rat hepatocytes on porous expanded polytetrafluoroethylene and their metabolic capacity
    Tokiwa T; Kano J; Zhou X; Meng X; Kodama M.
    Adv. Poly. Biomat. Sci./12/pp.133-136, 1997-01
  • Multilayer rat hepatocytes aggregates formed on expanded polytetrafluoroethylene surface
    Tokiwa T; Kano J; Meng X; Zhou X; Kodama M; Matsumura T.
    Cytotechnolgy/25/pp.137-144, 1997-01
  • Primary culture of adult rat hepatocytes on porous expanded polytetrafluoroethylene
    Tokiwa T; Kano J; Meng X; Kodama M.
    Transplantation Pro./129/pp.2120-2122, 1997-01
  • Restoration of differentiated functions in multicellular aggregates of a human liver epithelial cell line
    Tokiwa T; Kano J; Noguchi M; Kodama M; Tateishi T.
    Mat. Sci. Eng./C6/pp.249 -252, 1998-05
  • Polyacrylamide containing sugar residues: synthesis, characterization and hepatocyte attachment studies
    Bahulekar R; Tokiwa T; Kano J; Matsumura T; Kojima I; Kod...
    Biotech. Tech./12(10)/pp.721- 722, 1998-10
  • Colonial growth and differentiation of epithelial cells derived from abattoir adult porcine livers (共著)
    Junko Kano
    J of Gastroenterol. Hepatol./13/pp.S62- S69, 1998-01
  • Polyacrylamide containing sugar residues: synthesis, characterization and cell compatibility studies
    Bahulekar R; Tokiwa T. Kano J; Matsumura T; Kojima I; Kod...
    Carbohydrate Poly./37/pp.71-78, 1998-01
  • Isolation and primary culture of adult pig hepatocytes
    Zhou X; Tokiwa T; Kano J; Kodama M.
    Meth. Cell Sci./19/pp.277 -284, 1998-01
Books
  • がん転移研究の実験手法 レーザーアシステッドマイクロダイセクションによる遺伝子発現の検出法
    加野准子; 野口雅之
    2008-08
Conference, etc.
  • DKK3の酸化ストレス調節作用を介する抗アポトーシス機能にはxanthine oxidoreductaseが関与する
    Kano Junko
    第39回日本分子生物学会/2016-11-30
  • Dickkopf  3 (DKK3) attenuates xanthine dehydrogenase (XDH) expression to prevent oxidative stress-induced apoptosis
    Kano Junko
    第26回日本肝臓医生物研究会/2017-03-25--2017-03-25
  • Secreted glycoprotein,Dkk3 functions as an autocrine survival factor in Dkk3 expressing cell line
    野口 雅之; 加野准子
    第38回日本分子生物学会年会/2015-12-1--2015-12-4
  • 血清アミロイドP タンパク質(SAP)は肺腺癌の新たなバイオマーカーである
    野口 雅之; 坂田晃子; 戸嶋章太郎; 猪山慎治; 塩澤利博; 薄井...
    第104回日本病理学会総会/2015-04-30--2015-05-02
  • 肺腺癌におけるOCIAD2 発現の意義
    野口 雅之; 糸口直江; 中川智貴; 村田佳彦; 佐藤泰樹; 加野准...
    第104回日本病理学会総会/2015-04-30--2015-05-02
  • Laser microdissection identified cell-type-specific mutations in angioimmunoblastic T-cell lymphoma
    Yukitsugu Asabe; Mamiko Sakata-Yanagimoto; Daisuke Matsub...
    第76回 日本血液学会学術集会/2014-10-31--2014-11-02
  • Dkk3高発現細胞におけるDkk3の酸化ストレス調節による抗アポトーシス作用
    加野 准子
    第33回分子病理学研究会/2014-07-25--2014-07-26
  • Dkk3発現肝癌細胞においてDkk3は抗酸化ストレスに寄与する
    加野 准子
    第20回日本肝臓医生物学研究会/2014-02-15
  • Stratifin expressed in early invasive lung adenocarcinoma functionally enhances tumor progression and down-regulates SCFFbw7 ubiquitin ligase activity
    Shiba Aya; Iguchi Yukari; Morishita Yukio; Shiozawa Toshi...
    World Conference on Lung Cancer/2013-10-27--2013-10-31
  • Dkk3 contributes to oxidative stress resistance in the Dkk3-expressing hepatocellular carcinoma cell line, Li21
    Kano Junko
    72nd Annunal Meeting of the Japanese Cancer Association/2013-10-03--2013-10-05
  • 肝腫瘍におけるdickkopf 3の発現解析
    5. 裴一花; 加野准子; 稲留征典; 飯嶋達生; 野口雅之
    第15回肝細胞研究会/2008-06-28
Teaching
2017-04 -- 2017-08Advanced Exercise on Public HealthUniversity of Tsukuba.
2017-10 -- 2018-02Advanced Exercise on Public HealthUniversity of Tsukuba.
2017-04 -- 2017-08Internship IIUniversity of Tsukuba.
2017-10 -- 2018-02Internship IIUniversity of Tsukuba.
2017-04 -- 2017-06Human Pathology: LectureUniversity of Tsukuba.
2017-10 -- 2018-02Seminar on Basic Medical SciencesUniversity of Tsukuba.
2017-04 -- 2017-08Seminar on Basic Medical SciencesUniversity of Tsukuba.
2017-04 -- 2017-08Dissertation in Medical SciencesUniversity of Tsukuba.
2017-10 -- 2018-02Dissertation in Medical SciencesUniversity of Tsukuba.
2017-10 -- 2018-02Internship IUniversity of Tsukuba.
Talks
  • Dkk3発現肝がん細胞においてDkk3抑制が引き起こすアポトーシス機序の解明
    邱爽; 加野准子; 森下由紀雄; 野口雅之
    第71回日本癌学会学術総会/2012-09-21
  • Dkk3発現肝がん細胞においてDkk3抑制が引き起こすアポトーシス機序の解析
    邱爽; 加野准子; 森下由紀雄; 野口雅之
    第19回肝細胞研究会/2012-06-29
  • Dickkopf 3の抗アポトーシス機能
    加野准子; 邱爽; 森下由紀雄; 野口雅之
    第18回肝細胞研究会/2011-06-25
  • Establishment of hepatic stem-like cell lines from normal adult porcine liver in a poly-D-lysine-coated dish with NAIR-1 medium
    Junko Kano1; Tatsuo Iijima2; Yukio Morishita1; Masayuki N...
    The 3rd pan pacific symposium of stem cell research/2010-04-17
  • 肝腫瘍および背景肝におけるdickkopf 3 (Dkk3) の発現パターンの解析
    裴一花; 加野准子; 飯嶋達生; 森下由起雄; 野口雅之
    第96回日本病理学会総会/2007-04-15
  • 肝幹細胞様細胞差次的発現遺伝子dickkopf 3 (Dkk3) の初期胎仔肝および再生肝における発現上昇
    加野准子; 飯嶋達生; 森下由紀雄; 久倉勝治; 村田聡一郎; 大...
    第14回肝細胞研究会/2007-06-22
  • 肝幹細胞様細胞差次的発現遺伝子dickkopf 3 (Dkk3) の初期胎仔肝および再生肝における発現解析
    加野准子; 飯嶋達生; 森下由紀雄; 久倉勝治; 村田聡一郎; 大...
    第7回日本再生医療学会総会/2008-03-13
  • 成体肝幹細胞様細胞特徴的発現遺伝子の探索と胎仔肝、再生肝を用いた発現解析
    4. 加野准子; 裴一花; 飯嶋達生; 稲留征典; 森下由紀雄; 野口...
    第5回日本病理学会カンファレンス/2008-08-01
  • 悪性肝腫瘍におけるdickkopf3の発現とその診断応用
    2. 裴一花; 加野准子; 稲留征典; 飯嶋達生; 森下由紀雄; 野口...
    第98回日本病理学会総会/2009-05-31
  • 肝腫瘍における肝幹様細胞特徴的遺伝子dickkopf3の発現と機能解析
    裴一花; 加野准子; 飯嶋達生; 稲留征典; 森下由紀雄; 野口雅之
    第6回日本病理学会カンファレンス/2009-07-31

(Last updated: 2017-05-29)