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Hatano Kentaro

Affiliation
Faculty of Medicine
Official title
Associate Professor
Email
 
Office
学系棟103, Tsukuba Molecular Imaging Center
Phone
029-875-9970
Fax
029-853-0071
Research fields
Physical pharmacy
Drug development chemistry
Radiation science
Tumor diagnostics
Research keywords
Radiopharmaceutical Chemistry
Positron Emission Tomography
Nuclear Medicine
Fluorine Chemistry
Neurochemistry
Research projects
BNCT製剤早期実用化を実現する新規分子イメージング技術2015 -- 2016籏野 健太郎Japan Society for the Promotion of Science/Grant-in-Aid for challenging Exploratory Research3510000
Career history
1990-04 -- 1995-12Iwate Medical University Cyclotron Center Research Associate
1995-12 -- 2004-02National Chubu Hospital Department of Biofunctional Research, National Institute for Longevity Sciences Chief of Laboratory of Functional Assessment
2004-03 -- 2010-03National Center for Geriatrics and Gerontology Department of Brain Research, National Instiute for Longevity Sciences Chief of Laboratory of Brain Aging
2010-04 -- 2012-10National Center for Geriatrics and Gerontology Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia Chief of Laboratory of Imaging Molecules
2012-11 -- (current)University of Tsukuba Faculty of Medicine Associate Professor
Academic background
1980-04 -- 1985-03Tohoku University Faculty of Pharmaceutical Sciences 薬学科Graduated
1985-04 -- 1990-03Tohoku University Graduate School Faculty of Pharmaceutical Sciences 製薬化学専攻Completed
Degree
1990-03Ph DTohoku University
Licenses and qualifications
1987-02-17薬剤師
1997-05-15第一種放射線取扱主任者
Academic societies
2013-09 -- (current)Japanese Society of Neutron Capture Therapy(JSNCT)
2008-08 -- (current)THE SOCIETY OF FLUORINE CHEMISTRY, JAPAN
2007-04 -- (current)American Chemical Society
2001-10 -- (current)Society of Radiopharmaceutical Sciences
2000-04 -- (current)JAPAN SOCIETY FOR BIOMEDICAL GERONTOLOGY
1997-04 -- (current)JAPAN RADIOISOTOPE ASSOCIATION
1990-04 -- (current)Society of Nuclear Medicine
1990-04 -- (current)THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY
1985-10 -- (current)THE JAPANESE SOCIETY OF NUCLEAR MEDICINE
1985-10 -- (current)THE PHARMACEUTICAL SOCIETY OF JAPAN
Honors & Awards
2016-11久田賞(Annals of Nuclear Medicine賞)銅賞Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [11C]CB184 and [11C]CB190, as a PET tracer for 18 kDa tr
2001-10Japanese Society of Nuclear Medicine Award
Articles
  • Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [(11)C]CB184, in healthy human volunteers
    Sakata Muneyuki; Ishibashi Kenji; Imai Masamichi; Wagatsu...
    EJNMMI research/7(1)/p.26, 2017-12
  • 18F-FDGの品質管理-放射化学的純度について
    籏野 健太郎; 千田英輝; 徳田安則; 佐藤始広
    the Japanese journal of nuclear medicine/pp.S274-S274, 2016-9
  • Comparative study of specific activity of [11C]methyl iodide: A search for the source of carrier carbon.
    Iwata R; Ido T; Ujiie A; Takahashi T; Ishiwata K; Hatano ...
    Int J Radiat Isot Instr Part A Appl Radiat Isot/39(1)/p.1-7, 1988-01
  • Automated synthesis system with computer control for the production of [1-11C] fatty acids.
    Takahashi T; Ido T; Iwata R; Hatano K; Nakanishi H; Shino...
    Int J Radiat Isot Instr Part A Appl Radiat Isot/39(6)/p.659-665, 1988
  • D2-dopamine receptor specific brain uptake of carbon-11 labeled YM-09151-2.
    Hatano K; Ishiwata K; Kawashima K; Hatazawa J; Itoh M; Ido T
    J Nucl Med/30(4)/p.515-522, 1989
  • Visualization of histamine H1 receptors in dog brain by positron emission tomography.
    Yanai K; Watanabe T; Hatazawa J; Itoh M; Nunoki K; Hatano...
    Neurosci Lett/118(1)/p.41-44, 1990
  • Synthesis of ω-[18F]fluoroalkyl analogs of YM-09151-2 for the measurement of D2-dopamine receptors with PET.
    Hatano K; Ido T; Ishiwata K; Hatazawa J; Itoh M; Kawashim...
    Int J Radiat Isot Instr Part A Appl Radiat Isot/41(6)/p.551-555, 1990-01
  • Synthesis o 1-11C-labeled fatty acid from [11C]HCN.
    Takahashi T; Ido T; Hatano K; Iwata R; Nakanishi H
    Int J Radiat Isot Instr Part A Appl Radiat Isot/41(7)/p.649-657, 1990
  • A semi-automated synthesis system for routine preparation of [11C]YM-09151-2 and [11C]pyrilamine from [11C]methyl iodide.
    Iwata R; Hatano K; Yanai K; Takahashi T; Ishiwata K; Ido T
    Int J Radiat Isot Instr Part A Appl Radiat Isot/42(2)/p.202-205, 1991
  • Measurement of D2 dopamine receptor-specific carbon-11-YM-09151-2 binding in the canine brain by PET: Importance of partial volume correction.
    Hatazwa J; Hatano K; Ishiwata K; Itoh M; Ido T; Kawashima...
    J Nucl Med/32(4)/p.713-718, 1991
  • The synthesis of o- and p-[18F]fluorobenzyl bromides and their application to the preparation of labeled neuroleptics.
    Hatano K; Ido T; Iwata R
    J Labelled Compds Radiopharm/29(4)/p.373-380, 1991
  • 医療用小型サイクロトロン施設の概要
    二ツ川章二; 畠山智; 斎藤義弘; 世良耕一郎; 籏野健太郎; 佐...
    Radioisotopes/41/p.265-272, 1992
  • 医療用小型サイクロトロンの遮蔽
    二ツ川章二; 畠山智; 金子靖子; 斎藤義弘; 世良耕一郎; 籏野...
    Radioisotopes/42/p.31-36, 1993
  • Prospagnosia without topographagnosia and object agnosia associated with a lesion confined to the right occipitotemporal regin.
    Tohgi H; Watanabe K; Takahashi H; Yonezawa H; Hatano K; S...
    J Neurol/241/p.470-474, 1994
  • Agraphia and acalculia after a left prefrontal (F1, F2) infarction.
    Tohgi H Saitoh H Takahashi S Takahashi H Utsugisawa K Yon...
    J Neurol Neurosurg Psych/58(8)/p.629-632, 1995
  • Linearized method: A new approach for kinetic analysis of centrral dopamine D2 receptor specific binding.
    Watabe H; Hatazawa J; Ishiwata K; Ido T; Itoh M; Iwata R;...
    IEEE Trans Med Imaging/14(4)/p.658-696, 1995
  • Co-production of 2,6-[18F]DifluoroDOPA during electrophilic synthesis of 6-[18F]Fluoro-L-DOPA.
    Hatano K; Ishiwata K; Yanagisawa T
    Nucl Med Biol/23(1)/p.101-103, 1996
  • Vocal identification of speaker and emotion activates different brain region.
    Imaizumi S; Mori K; Kiritani S; Kawashima R; Sugiura M; F...
    Neuroreport/8/p.2809-2812, 1997
  • Carbon-11 labeled ethionine and propionine as tumor detecting agents.
    Ishiwata K; Kasahara C; Hatano K; Ishii S; Senda M
    Ann Nucl Med/11(2)/p.115-122, 1997
  • Neuroanatomical correlates of the assessment of facial attractiveness.
    Nakamura K; Kawashima R; Nagumo S; Ito K; Sugiura M; Kato...
    Neuroreport/9/p.753-757, 1998
  • Cerebral blood flow and oxygen metabolism in senile dementia of Alzheimer's type and vascular dementia with deep white matter changes.
    Tohgi H; Yonezawa H; Takahashi S; Sato N; Kato E; Kudo M;...
    Neuroradiol/40(3)/p.131-137, 1998
  • Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET s receptor ligand.
    Ishiwata K; Noguchi J; Ishii S-I; Hatano K; Ito K; Nabesh...
    Nucl Med Biol/25(3)/p.195-202, 1998
  • Fluorine-18 labeling of methionine derivatives in the presence of xenon difluoride.
    Hatano K
    Chem Pharm Bull/46(8)/p.1337-1338, 1998
  • Radiosynthesis of [18F]N-(4-phenylbutyl)-4-(4-fluorobenzoyl)piperidine for studying serotonin 5-HT2A receptors.
    Hashimoto K; Hatano K; Minabe Y; Iyo M; Taniguchi M; Saki...
    J Labelled Compds Radiopharm/41(10)/p.941-949, 1998
  • Activation of the right inferior frontal cortex during assessment of facial emotion.
    Nakamura K; Kawashima R; Ito K; Sugiura M; Kato T; Nakamu...
    J Neurophysiol/1999/p.1610-1614, 1999
Books
  • PET用放射性薬剤の製造および品質管理ー合成と臨床使用へのてびきー
    高橋和弘; 豊原潤; 籏野 健太郎
    2015-02
  • 炭素-11およびフッ素-18標識神経遮断薬の合成とD2-ドーパミン受容体の測定
    籏野 健太郎
    1990-03
  • クリニカルPETの最前線
    古本祥三; 籏野健太郎; 西嶋剣一; 石渡喜一
    2004
  • 核医学Q&A(改訂版)
    籏野健太郎
    2006
  • 臨床医のためのクリニカルPET―病期・病態診断のためのガイドブックー
    籏野健太郎
    2007
  • 臨床医とコメディカルのための最新クリニカルPET
    籏野健太郎
    2010
  • 遺伝子医学MOOK18創薬研究への分子イメージング応用
    外山宏; 籏野健太郎; 鈴木弘美
    2010
Conference, etc.
  • 18O2をターゲットとする2回照射法による18F2の製造と18F-FBPA合成への適用
    Hatano Kentaro; 千田英輝; 徳田良則; 佐藤始広
    第13回中性子捕捉療法学会学術大会/2016-08-06--2016-08-07
  • 中性子捕捉療法施行に向けたPET診断薬18F標識FBPAの合成
    Hatano Kentaro; 千田英輝; 徳田安則; 佐藤始広
    第56回日本核医学会学術総会/2016-11-03--2016-11-05
  • 中性子捕捉療法施行に向けたPET診断薬18F-FBPAの合成
    籏野 健太郎; 徳田安則; 千田英輝; 佐藤始広
    つくば医工連携フォーラム2016/2016-1-22--2016-1-22
  • 18O(p,n)18F核反応による求電子的18F標識薬18F2の製造
    籏野 健太郎; 徳田安則; 佐藤始広
    第38回フッ素化学討論会/2015-9-17--2015-9-18
  • 18F-FDGの品質管理-放射化学的純度について
    籏野 健太郎; 千田英輝; 徳田安則; 佐藤始広
    第55回日本核医学会学術総会/2015-11-5--2015-11-7
  • PET用放射性医薬品の製造と開発
    籏野 健太郎
    日本核医学技術学会関東地方会第31回インフォーマルミーティング/2015-10-3--2015-10-3
  • Introduction of Imaging-facility in Univ. of Tsukuba
    Hatano Kentaro
    Global Frontiers of Imaging for the Diagnosis and Treatment of Cancer/2014-05-09--2014-05-09
  • メタルフリーな酸化的合成
    籏野 健太郎
    PET化学ワークショップ2013(第22回)/2013-02-08--2013-02-10
Teaching
2018-01 -- 2018-02Introduction for clinical pharmacologyUniversity of Tsukuba.
2017-01 -- 2017-02Introduction for clinical pharmacologyUniversity of Tsukuba.
2015-10 -- 2015-12Pharmaceutical SciencesUniversity of Tsukuba.
2014-10 -- 2014-12Pharmaceutical SciencesUniversity of Tsukuba.
2013-10 -- 2013-10臨床薬剤学特論フロンティア医科学専攻
Professional activities
2012-04 -- (current)日本核医学会PET薬剤基準小委員会委員
2010-07 -- (current)小動物インビボイメージング研究会幹事
2007-08 -- 2009-08日本核医学会PET核医学分科会執行委員
1996-02 -- (current)PET化学ワークショップ幹事

(Last updated: 2017-05-24)