坂下 信悟(サカシタ シンゴ; Sakashita, Shingo)

所属

医学医療系

職名

准教授

eメール

0|(|0%&+$,@OK%,1*|&)I ,* 

研究課題

RNA Sequenceを用いた粘液性肺腺癌の解析 研究課題	2017-04 -- 2020-03	坂下信悟	科研費/科研費　基盤研究(C)	4,680,000円
患者由来XGマウスを用いたIGBP1関連miRNA の肺癌治療における機序の検討	2015-04 -- 2017-03	坂下信悟	科研費/学術研究助成基金助成金（若手研究(B)	4,030,000円
初期肺腺癌におけるＩＧＢＰ１の抗アポトーシス機能の解明	2012 -- 2013	坂下信悟	日本学術振興会/若手研究(B)	2,210,000円

免許資格等

2011-12	日本臨床細胞学会細胞診専門医
2011-08	日本病理学会病理専門医
2009-12	死体解剖資格
2005-04	医師免許

論文

• miR-3941: A Novel microRNA That Controls IGBP1 Expression and is Associated with Malignant Progression of Lung Adenocarcinoma
  Sato Taiki; Shiba Aya; Kim Yun-Jung; Dai Tomoko; Sakashit...
  JOURNAL OF THORACIC ONCOLOGY/12(1::S)/pp.S792-S792, 2017-01
• Biological Implication of Cytoplasmic ECT2 in Malignant Progression of Lung Adenocarcinoma
  Kosibaty Zeinab; Murata Yoshihiko; Minami Yuko; Sakashita...
  JOURNAL OF THORACIC ONCOLOGY/12(1::S)/pp.S830-S831, 2017-01
• A novel therapeutic strategy for pancreatic cancer: targeting cell surface glycan using rBC2LC-N lectin-drug conjugate (LDC)
  Shimomura Osamu; Oda Tatsuya; Tateno Hiroaki; Ozawa Yusuk...
  Molecular cancer therapeutics/17(1)/pp.183-195, 2017-09
  PubMed
• A phase-I study of lapatinib in combination with foretinib, a c-MET, AXL and vascular endothelial growth factor receptor inhibitor, in human epidermal growth factor receptor 2 (HER-2)-positive metastatic breast cancer
  Sakashita Shingo; Chia StephenK.; Ellard Susan L.; Mates ...
  Breast Cancer Research, 2017-05
  PubMed
• A phase I study of foretinib plus erlotinib in patients with previously treated advanced non-small cell lung cancer: Canadian cancer trials group IND.196.
  Sakashita Shingo; Natasha B. Leighl Ming-Sound Tsao Geoff...
  Oncotarget., 2017-06
  PubMed
• Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma
  Kim Yunjung; Shiba-Ishii Aya; Nakagawa Tomoki; Husni Ryan...
  Pathology international/67(6)/pp.292-301, 2017-05
  PubMed
• Cetuximab Inhibits T790M-Mediated Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in a Lung Adenocarcinoma Patient-Derived Xenograft Mouse Model.
  Petra Martin; Erin Stewart; Nhu-An Pham; Celine Mascaux; ...
  Clin Lung Cancer., 2016-01
• Postoperative Decrease in Platelet Counts Is Associated with Delayed Liver Function Recovery and Complications after Partial Hepatectomy.
  Kazuhiro Takahashi; Tomohiro Kurokawa; Yukio Oshiro; Kiyo...
  Tohoku J Exp Med./239(1)/pp.47-55, 2016-05
• 先天性胆道拡張症と胆道閉鎖症(I cyst)との鑑別が困難な胆道奇形の1例
  坂元 直哉; 藤代 準; 小室 広昭; 瓜田 泰久; 星野 論子; 小野...
  日本小児外科学会雑誌/47(7)/pp.1021-1025, 2011-12
  CiNii
• 2.これまでの病型分類が当てはまらない胆道閉鎖症の症例 : 十二指腸への交通を認めた肝門部嚢胞型胆道閉鎖症(セッション2.「診断」,第37回日本胆道閉鎖症研究会)
  坂元 直哉; 藤代 準; 小室 広昭; 瓜田 泰久; 星野 論子; 小野...
  日本小児外科学会雑誌/47(5)/pp.866-867, 2011-08
  CiNii
• Specific expression of ZO-1 and N-cadherin in rosette structures of various tumors: possible recapitulation of neural tube formation in embryogenesis and utility as a potentially novel immunohistochemical marker of rosette formation in pulmonary neuroendocrine tumors
  Satomi Kaishi; Morishita Yukio; Sakashita Shingo; Kondou ...
  VIRCHOWS ARCHIV/459(4)/pp.399-407, 2011-10
• IMMUNOGLOBLIN BINDING PROTEIN 1 (IGBP1) IS A KEY PROTEIN RELATED TO ANTI-APOPTOTIC ACTIVITY IN LUNG ADENOCARCINOMA
  Sakashita Shingo; Li Dongping; Tachibana Keisei; Minami Y...
  JOURNAL OF THORACIC ONCOLOGY/6(6::Suppl. S), 2011-06

会議発表等

• miR-3941 targets IGBP1 and is associated with malignant progression of lung adenocarcinoma
  佐藤 泰樹; 柴　綾; 坂下　信悟; 野口　雅之; 加野　准子
  日本病理学会総会/2017-4-28

担当授業科目

2017-04 -- 2017-06	人体病理学概論	筑波大学
2017-10 -- 2017-12	腫瘍学	筑波大学
2016-04 -- 2016-06	フレッシュマン・セミナー	筑波大学

(最終更新日: 2018-04-05)