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Chiba Tomoki

Researcher's full information

  • TBP-interacting protein 120b (TIP120B) /cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiaton.
    Shiraishi S; Zhou C; Aoki T; Sato N; Chiba T; Tanaka K; Y...
    J Biol Chem./282/p.9017-9028, 2007-01
  • SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
    Yao I; Takagi H; Ageta H; Kahyo T; Sato S; Hatanaka K; Fu...
    Cell/130/p.943 - 957, 2007-01
  • Loss of autophagy in the central nervous system causes neurodegeneration in mice
    Chiba Tomoki
    Nature, 2006-06
  • Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography.
    Sato S; Chiba T; Nishiyama S; Kakiuchi T; Tsukada H; Hata...
    J. Neurosci. Res/84/p.1350-1357, 2006-01
  • BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.
    Kwon JE; La M; Oh KH; Oh YM; Kim GR; Seol JH; Baek SH; Ch...
    J. Biol. Chem./281(18)/p.12664, 2006-01
  • Excess peroxisomes are degraded by autophagic machinery in mammals.
    Iwata J; Ezaki J; Komatsu M; Yokota S; Ueno T; Tanida I; ...
    J. Biol. Chem/281/p.4035, 2006-01
  • SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination.
    5. Lee MH; Lee SW; Lee EJ; Choi SJ; Chung SS; Lee JI; Cho...
    Nat Cell Biol./8/p.1424-1431, 2006-01
  • Depletion of hsp90beta induces multiple defects in B cell receptor signaling.
    Shinozaki F; Minami M; Chiba T; Suzuki M; Yoshimatsu K; I...
    J. Biol. Chem./281(14)/p.16361, 2006-01
  • Loss of autophagy in the central nervous system causes neurodegeneration in mice.
    Komatsu M; Waguri S; Chiba T; Murata S; Iwata J; Tanida I...
    Nature/441/p.880, 2006-01
  • 14-3-3eta is a novel regulator of parkin ubiquitin ligase.
    Sato S; Chiba T; Sakata E; Kato K; Mizuno Y; Hattori N; T...
    EMBO J./25/p.211-221, 2006-01
  • Analysis of knock-out mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity.
    Fujiwara T; Mishima T; Kofuji T; Chiba T; Tanaka K; Yamam...
    J Neurosci./26/p.5767-5776, 2006-01
  • The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells.
    Duan X; Hisaeda H; Shen J; Tu L; Imai T; Chou B; Murata S...
    Int Immunol./18/p.679-687, 2006-01
  • The involvement of immunoproteasomes in induction of MHC class I-restricted immunity targeting Toxoplasma SAG1.
    Ishii K; Hisaeda H; Duan X; Imai T; Sakai T; Fehling HJ; ...
    Microbes Infect./8/p.1045-1053, 2006-01
  • DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.
    Chiba Tomoki
    DNA repair, 2005-05
  • A novel DNA vaccine based on ubiquitin-proteasome pathway targeting 'self'-antigens expressed in melanoma/melanocyte.
    Zhang M; Obata C; Hisaeda H; Ishii K; Murata S; Chiba T; ...
    Gene Ther./12/p.1049-1057, 2005-01
  • In vitro systems for NEDD8 conjugation by Ubc12.
    Chiba T.
    Methods Enzymol./398/p.68-73, 2005-01
  • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
    Komatsu M; Waguri S; Ueno T; Iwata J; Murata S; Tanida I;...
    J. Cell Biol./169/p.425-434, 2005-01
  • Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor
    Tateishi Y; Kawabe Y; Chiba T; Murata S; Ichikawa K; Mura...
    EMBO JOURNAL/23(24)/pp.4813-4823, 2004-12
  • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    Kobayashi Akira; Kang Moon-Il; Okawa Hiromi; Ohtsuji Maki...
    Mol. Cell Biol./24(16)/pp.7130-7139, 2004-08
  • Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation
    Chiba Tomoki
    Microbes and Infection, 2004-07
  • A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier
    千葉 智樹
    EMBO J, 2004-04
  • Structural basis of sugar-recognizing ubiquitin ligase
    千葉 智樹
    Nat.Struct.Mol.Biol, 2004-02
  • Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains
    Chiba Tomoki
    J.Biol.Chem., 2003-10
  • Proteasome activator PA28γ-dependent nuclear retention and degradation of hepatitis C virus core protein
    Chiba Tomoki
    J.Virol., 2003-10
  • CHIP: a quality-control E3 ligase collaborating with molecular chaperones
    Chiba Tomoki
    The International Journal of Biochemistry & Cell Biology, 2003-05