Ohneda Osamu
- Affiliation
- Faculty of Medicine
- Official title
- Professor
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- Fax
- 029-853-2938
- Research fields
Cell biology Developmental biology - Research projects
間葉系幹細胞由来機能性細胞外小胞体の臨床応用に向けた研究開発 2021 -- 2023 大根田 修 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,160,000Yen 2型糖尿病由来間葉系幹細胞の単離およびその機能解析 2016 -- 2018 大根田 修 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,810,000Yen 2型糖尿病由来間葉系幹細胞の単離およびその機能解析 2016 -- 2018 大根田修 JSPS/基盤研究(C) 4,810,000Yen ヒト初代培養乳癌幹細胞における浸潤・転移能獲得の分子機能解明 2013 -- 2015 坂東裕子 JSPS/Kiban Kenkyu (c) 4,940,000Yen 機能性間葉系幹細胞の単離とその機能解析 2012 -- 2014 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 5,590,000Yen 虚血性疾患治療に効果的な血管内皮前駆細胞の機能解析 2008 -- 2010 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 4,550,000Yen "新規ケモカイン""WECHE""の造血・発生における機能解析" 2002 -- (current) 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 6,000,000Yen 脳腫瘍に対する血管新生抑制療法の展開:新規治療法と抵抗性の克服 2009 -- 2011 高野晋吾 JSPS/Kiban Kenkyu B 17,550,000Yen - Academic background
-- 1987 Tohoku University Faculty of Medicine -- 1993 Tohoku University Graduate School, Division of Medicine 内科学 - Degree
Doctor of Medicine Tohoku University - Academic societies
-- (current) The Japanese Cancer Association -- (current) THE JAPANESE SOCIETY OF HEMATOLOGY -- (current) THE JAPANESE BIOCHEMICAL SOCIETY -- (current) The Molecular Biology Society of Japan -- (current) THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE -- (current) THE JAPANESE CIRCULATION SOCIETY -- (current) American Society of Hematology - Honors & Awards
2000 日本血液学会奨励賞 - Articles
- Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Chang Yun-Hsuan; Vuong Cat-Khanh; Ngo Nhat-Hoang; Yama...
Scientific reports/12(1), 2022-08-08 - Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills.
Ho Kiong; Mayers Thomas David; Morikawa Kazuya; Watanabe ...
Journal of Medical English Education./20(1)/pp.39-46, 2021-10 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Nguyen Hoai-Nga Thi; Kawahara Marie; Vuong Cat-Khanh; Fuk...
Front. Oncol., 2022-06 - Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills
Ho C. Kiong; Mayers Thomas David; Morikawa Kazuya; Watana...
Journal of Medical English Education/20(3)/pp.39-46, 2021-10 - COVID-19 as a Research Dynamic Transformer: Emerging Cross-Disciplinary and National Characteristics
Ohniwa Ryosuke L.; Kijima Joji; Fukushige Mizuho; Ohneda ...
Frontiers in Big Data/4/p.Article 631073, 2021-7 - Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions
Khanh Vuong Cat; Fukushige Mizuho; Chang Yun-Hsuan; Hoang...
Stem Cells and Development/30(15)/pp.758-772, 2021-08 - Type 2 diabetes mellitus induced paracrine effects on breast cancer metastasis via extracellular vesicles derived from human mesenchymal stem cells
Khanh Vuong Cat; Fukushige Mizuho; Moriguchi Kana; Yamash...
Stem Cells and Development/29(21)/pp.1382-1394, 2020-09 - Dynamic Changes of Mouse Embryonic Stem Cell-Derived Neural Stem Cells Under In Vitro Prolonged Culture and Hypoxic Conditions
Lukmanto Donny; Khanh Vuong Cat; Shirota Saori; Kato Tos...
Stem Cells and Development/28(21)/pp.1434-1450, 2019-11 - An international exchange program for undergraduate medical science students.
Mayers Thomas; Morikawa Kazuya; Ho Kiong; Ohneda Osamu
J Med Eng Educ/17(1)/pp.7-13, 2018-04 - Glucosamine decreases the stemness of human ALDH breast cancer stem cells by inactivating STAT3
Hosea Rendy; Hardiany Novi Silvia; Ohneda Osamu; Wanan...
Oncology letters/16(4)/pp.4737-4744, 2018-10 - Glucocorticoid Impaired the Wound Healing Ability of Endothelial Progenitor Cells by Reducing the Expression of CXCR4 in the PGE2 Pathway
Carolina Erica; Kato Toshiki; Vuong Cat Khanh; Moriguchi ...
Frontiers in Medicine/5, 2018-09 - Deterioration of alveolar development in mice with both HIF-3α knockout and HIF-2α knockdown
Amin Firman Zulkifli; Yamashita Toshiharu; Ohneda Osamu
BMC research notes/11(1)/p.449, 2018-07 - Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
Ho Kiong; Mayers Thomas; Ohneda Osamu
Journal of Medical English Education/17(1)/pp.7-13, 2018-02 - An international exchange program for undergraduate medical science students
Mayers Thomas David; Morikawa Kazuya; Ho C. Kiong; Ohneda...
Journal of Medical English Education/17(1)/pp.7-13, 2018-02 - Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
Khanh Vuong Cat; Zulkifli Amin Firman; Tokunaga Chiho; Ya...
Biochemical and biophysical research communications/500(3)/pp.682-690, 2018-04 - Elevated Expression of Dkk-1 by Glucocorticoid Treatment Impairs Bone Regenerative Capacity of Adipose Tissue-Derived Mesenchymal Stem Cells.
Vuong Cat Khanh; Kimura Kenichi; Kato Toshiki; Sato Kazu...
Stem Cells and Development, 2018-01 - Comparative Analysis of Cellular and Growth Factor Composition in Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma
Sugaya Hisashi; Yoshioka Tomokazu; Kato Toshiki; Taniguch...
BONE MARROW RESEARCH/2018, 2018 - In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche
Breitbach Martin; Kimura Kenichi; Luis Tiago C.; Fuegeman...
CELL STEM CELL/22(2)/pp.262-+, 2018-02 - A chemokine receptor, CXCR4, which is regulated by hypoxia inducible factor 2α, iscrucial for functional EPC migration to ischemic tissue and wound repair.
Tu Tran Cam; Nagano Masumi; Yamashita Toshiharu; Hamada ...
Stem Cells Dev./25/pp.266-276, 2016-02 - Elevated expression of Dkk-1 by glucocorticoid treatment impairs bone regenerative capacity of adipose tissue-derived mesenchymal stem cells
Kato Toshiki; Khanh Vuong Cat; Sato Kazutoshi; Kimura ...
Stem cells and development/27(2)/pp.85-99, 2017-10 - SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells
Kato Toshiki; Khanh Vuong Cat; Sato Kazutoshi; Takeuch...
Biochemical and biophysical research communications/493(2)/pp.1010-1017, 2017-09 - Uremic Toxins Affect the Imbalance of Redox State and Overexpression of Prolyl Hydroxylase 2 in Human Adipose Tissue-Derived Mesenchymal Stem Cells Involved in Wound Healing
Khanh Vuong Cat; Ohneda Kinuko; Kato Toshiki; Yamashit...
Stem cells and development/26(13)/pp.948-963, 2017-05 - Microvesicles derived from Alde-Low EPCs support the wound healing capacity of AT-MSCs
Matsuo-Takasaki Mami; TC Tu; T Yamashita; Y Kato; M Naga...
Biochem Biophys Res Com/477(1)/pp.68-75, 2016-08 - Dual Functions of Hypoxia-Inducible Factor 1 Alpha for the Commitment of Mouse Embryonic Stem Cells Toward a Neural Lineage
Zhao Yang; Takasaki Mami; Tsuboi Ikki; Kimura Kenichi; Sa...
Stem Cells Dev., 2014 - Microvesicles derived from Alde-Low EPCs support the wound healing capacity of AT-MSCs
Tran Cam Tu; Yamashita Toshiharu; Kato Toshiki; Nagano M...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016-08 - more...
- Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
- Conference, etc.
- Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3 alpha In Vivo
Pan Xiaoqing; Suzuki Norio; Hirano Ikuo; Yamazaki Shun; Y...
52nd Annual Meeting of the American-Society-of-Hematology (ASH)/2010-12-04--2010-12-07 - A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a
Nagano Masumi; Kimura Ken-ichi; Yamashita Toshiharu; Hama...
50th Annual Meeting of the American- Society-of-Hematology/2008-12-6--2008-12-9 - THE ROLE OF CHEMOKINE SDF-1 AND CXCR4 IN GLIOMA ANGIOGENESIS AND INVASIVENESS: INTERACTION BETWEEN GLIOMA AND GLIOMA-DERIVED ENDOTHELIAL CELLS
Takano Shingo; Osuka Satoru; Mashiko Ryota; Ohneda Osamu...
17th International Conference on Brain Tumor Research and Therapy/2008-06-09--2008-06-12 - THE ROLE OF CHEMOKINE SDF-1/CXCR4/CXCR7 FOR GLIOBLASTOMA ANGIOGENESIS AND GLIOBLASTOMA-DERIVED ENDOTHELIAL CELLS
Takano Shingo; Yamashita Toshio; Nagano Masumi; Mashiko ...
3rd Quadrennial Meeting of the World-Federation-of-Neuro-Oncoloyg/6th Meeting of the Asian-Society-for-Neuro-Oncology
- Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3 alpha In Vivo
- Teaching
2021-10 -- 2022-02 Special Research in Human Biology II University of Tsukuba. 2021-10 -- 2022-02 Special Seminars in Human Biology II University of Tsukuba. 2021-10 -- 2022-02 Special Lectures in Human Biology II University of Tsukuba. 2021-10 -- 2022-02 Basic Experiments in Human Biology University of Tsukuba. 2021-10 -- 2021-12 Entrepreneurship Training I University of Tsukuba. 2021-04 -- 2021-06 Stem Cell Therapy University of Tsukuba. 2021-10 -- 2022-02 Advanced Entrepreneurship Practice University of Tsukuba. 2021-04 -- 2021-08 Advanced Entrepreneurship Practice University of Tsukuba. 2021-10 -- 2021-12 Agro-Biomedical Science Laboratory Seminar I University of Tsukuba. 2021-10 -- 2021-12 Entrepreneurship Training II University of Tsukuba. more... - Talks
- 治療効果の高い間葉系幹細胞の単離およびその機能解析.
大根田 修
日本生化学会 関東支部例会/2009-04-01 - ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療と機能解析.
大根田 修
日本生化学会 関東支部例会/2009-04-01 - ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療に向けた研究開発.
大根田 修
第8回 日本再生医療学会総会/2009-04-01 - 治療効果の高い間葉系幹細胞の単離およびその機能解析.
大根田 修
第8回 日本再生医療学会総会/2009-04-01 - Differential Potential of Endothelial Progenitor Cells to Promote Arteriogenesis and Angiogenesis.
大根田 修
Cardiovascular Research Technologies/2009-04-01 - CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation by HIF-2a.
大根田 修
第73回 日本循環器学会総会・学術集会/2009-04-01 - 赤血球分化における低酸素応答転写因子HIF-2aの機能解析.
大根田 修
第70回 日本血液学会総会/2008-04-01 - 虚血改善効果の高いヒト血管内皮前駆細胞における低酸素応答転写因子の機能解析.
大根田 修
第70回 日本血液学会総会/2008-04-01 - 膠芽腫由来血管内皮細胞の特性から考える血管新生抑制療法.
大根田 修
第67回 日本癌学会学術総会/2008-04-01 - 生体内におけるHIF-3a /IPAS発現部位の同定.
大根田 修
第6回 がんとハイポキシア研究会/2008-04-01 - HIF-3aによる負の転写制御機構解明.
大根田 修
第6回 がんとハイポキシア研究会/2008-04-01 - A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a.
大根田 修
50th ASH Annual Meeting/2008-04-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第4回 麒麟塾/2008-04-01 - ヒト臍帯血由来間葉系幹細胞の単離と同定.
大根田 修
第7回 日本再生医療学会/2008-04-01 - 治療効果・安全性が高い細胞単離/保存方法の開発
大根田 修
TX テクノロジー・ショーケース イン ツクバ 2008/2008-01-01 - Analyses of functional roles of HIFs in endothelial cells
大根田 修
ERATO シンポジウム/2007-11-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第5回がんとハイポキシア研究会/2007-11-01 - 新規bHLH/PAS転写因子 NEPAS の機能解析
大根田 修
第5回がんとハイポキシア研究会/2007-11-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第69回日本血液学会/2007-10-01 - GATA-1遺伝子変異細胞株(GAK14)を用いたGATA-1N末端の機能解析
大根田 修
第69回日本血液学会/2007-10-01 - HIF-2α in endothelial cells regulates tumor neovascularization through activation of ephrin A1
大根田 修
第66回日本癌学会/2007-10-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第6回日本再生医療学会/2007-03-01 - 新規bHLH/pas転写因子の機能解析
大根田 修
第29回日本分子生物学会/2006-12-01 - 血管内皮前駆細胞を用いたグリオーマに対する血管新生抑制療法
大根田 修
第14回日本血管生物医学会/2006-12-01 - ヒト臍帯血由来間葉系幹細胞の遊走能解析
大根田 修
第11回つくばバイオマテリアル研究会「再生医療とナノメディシン」/2006-11-01 - more...
- 治療効果の高い間葉系幹細胞の単離およびその機能解析.
- Professional activities
-- (current) THE JAPANESE BIOCHEMICAL SOCIETY 評議委員 - University Management
2017-04 -- 2018-03 生命システム医学専攻 運営委員、国際連携委員 2017-04 -- 2018-03 フロンティア医科学専攻 運営委員、教務委員、国際連携委員、財務委員 2013-04 -- 2017-03 国際室 国際室長、国際戦略会議議長
(Last updated: 2022-01-17)