Irie Kenji

Affiliation

Faculty of Medicine

Official title

Professor

URL

http://www.md.tsukuba.ac.jp/public/basic-med/molcellbiol/index.html

Email

@>G>:XgcB9aIHJ@J76a68a?E 

Research fields

Cell biology

Molecular biology

Research keywords

Cell polarity

Asymmetric cell division

mRNA localization

Research projects

ポリＡ鎖を介したｍＲＮＡレベルの遺伝子発現制御と栄養源シグナルによる調節	2018 -- 2020	入江 賢児	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)	4,550,000Yen
ＲＮＡ制御系によるｍＲＮＡ安定性と翻訳の時空間ファインチューニング	2015 -- 2017	入江　賢児	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)	5,200,000Yen
ＲＮＡ結合タンパク質によるｍＲＮＡ安定性と翻訳のファインチューニング	2012 -- 2014		Japan Society of for the Promotion of Science/基盤研究(C)	2,210,000Yen
ＲＮＡ結合タンパク質による膜タンパク質の小胞体輸送経路の選別機構と品質管理	2010 -- 2011		Ministry of Education, Culture, Sports, Science and Technology, Japan/特定領域研究	2,200,000Yen
ＲＮＡ局在と局所的翻訳制御を介した細胞極性の形成と細胞の運命決定機構	2009 -- 2011		Japan Society of for the Promotion of Science/基盤研究(B)	18,720,000Yen
ＲＮＡ検出用デグラトンプローブの開発とＲＮＡ制御機構の解析	2009 -- 2010		Japan Society of for the Promotion of Science/挑戦的萌芽研究	3,000,000Yen
ＲＮＡ結合タンパク質による膜タンパク質の小胞体輸送経路の選別機構と品質管理	2008 -- 2009		Ministry of Education, Culture, Sports, Science and Technology, Japan/特定領域研究	6,100,000Yen
細胞間接着シグナリングによる細胞極性の形成機構	2006 -- 2008		Japan Society of for the Promotion of Science/基盤研究(B)	16,460,000Yen
ＲＮＡ局在と翻訳制御による非対称分裂の制御機構	2005 -- 2006		Ministry of Education, Culture, Sports, Science and Technology, Japan/特定領域研究	3,000,000Yen

Career history

1991-01 -- 2000-12	名古屋大学 理学部 助手
2000-12 -- 2001-12	大阪大学 大学院医学系研究科 助手
2002-01 -- 2005-03	大阪大学 大学院医学系研究科 助教授

Degree

博士(理学)

Nagoya University

Articles

• Pop2 phosphorylation at S39 contributes to the glucose repression of stress response genes, HSP12 and HSP26
  Lien Pham Thi Kim; Viet Nguyen Thi Minh; Mizuno Tomoaki; ...
  PloS one/14(4), 2019-04
  PubMed Tsukuba Repository
• Regulation of LRG1 expression by RNA binding protein Puf5 in the budding yeast cell wall integrity pathway
  Nguyen Viet Thi Minh; Duong Duy Long; Saito Kazuhiro; Iri...
  Genes to cells : devoted to molecular & cellular mechanisms/23(12)/pp.988-997, 2018-10
  PubMed
• Induction of Ptp2 and Cmp2 protein phosphatases is crucial for the adaptive response to ER stress in Saccharomyces cerevisiae
  Mizuno Tomoaki; Nakamura Meyu; Irie Kenji
  Scientific reports/8(1), 2018-08
  PubMed Tsukuba Repository
• Activation of Rab GTPase Sec4 by its GEF Sec2 is required for prospore membrane formation during sporulation in yeast Saccharomyces cerevisiae
  Suda Yasuyuki; Tachikawa Hiroyuki; Inoue Ichiro; Kurita T...
  FEMS yeast research/18(1), 2017-12
  PubMed
• Expression control of the AMPK regulatory subunit and its functional significance in yeast ER stress response
  Kimura Yuichi; Irie Kenji; Mizuno Tomoaki
  Scientific reports/7, 2017-04
  PubMed Tsukuba Repository
• Cytoplasmic deadenylase Ccr4 is required for translational repression of LRG1 mRNA in the stationary phase
  Duy Duong Long; Suda Yasuyuki; Irie Kenji
  PLOS ONE/12(2), 2017-02
  PubMed Tsukuba Repository
• Different Regulations of ROM2 and LRG1 Expression by Ccr4, Pop2, and Dhh1 in the Saccharomyces cerevisiae Cell Wall Integrity Pathway
  Li Xia; Ohmori Tetsuro; Irie Kaoru; Kimura Yuichi; Suda Y...
  MSPHERE/1(5), 2016-09
  PubMed Tsukuba Repository
• Analysis of the Physiological Activities of Scd6 through Its Interaction with Hmt1
  Pham Thi Kim Lien; Izumikawa Keiichi; Muroi Kei; Irie Kao...
  PLoS One/11(10), 2016-10
  PubMed Tsukuba Repository
• Enhancement of protein production via the strong DIT1 terminator and two RNA-binding proteins in Saccharomyces cerevisiae
  Ito Yoichiro; Kitagawa Takao; Yamanishi Mamoru; Katahira ...
  SCIENTIFIC REPORTS/6, 2016-11
  PubMed Tsukuba Repository
• Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential
  Wang Yen-Wen; Hong Tzu-Wen; Tai Yu-Ling; Wang Ying-Jing; ...
  EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE/2015, 2015
  PubMed
• The Saccharomyces cerevisiae AMPK, Snf1, Negatively Regulates the Hog1 MAPK Pathway in ER Stress Response
  Mizuno Tomoaki; Masuda Yuto; Irie Kenji
  PLOS GENETICS/11(9), 2015-09
  PubMed Tsukuba Repository
• Pbp1 is involved in the Ccr4 and Khd1-mediated regulation of cell growth through the association with ribosomal proteins, Rpl12a and Rpl12b.
  Kimura Y Irie K Irie K
  Eukaryotic Cell/12(6)/pp.864-874, 2013-06
• Brap2 regulates temporal control of NF-kB localization mediated by inflammatory response
  Takashima O; Tsuruta F; Kigoshi Y; Nakamura S; Kim J; Kat...
  PLoS ONE/8(e58911), 2013-3
• Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase.
  Irie K; et al.
  Science/265/p.1716 1719, 1994-01
• Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction.
  Yamaguchi K; et al.; +入江 賢児
  Science/270/p.2008 2011, 1995-01
• Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF.
  Tadauchi T; et al.; +入江 賢児
  The EMBO journal/20/p.552 561, 2001-01
• The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast.
  Irie K; et al.
  The EMBO journal/21/p.1158 1167, 2002-01
• Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development.
  Inagaki M; et al.; +入江 賢児
  Development/132/p.1525 1537, 2005-01
• Stability control of MTL1 mRNA by the RNA-binding protein Khd1p in yeast.
  Mauchi N; Ohtake Y; Irie K.
  Cell structure and function/35(2)/pp.95-105, 2010-01
  PubMed
• Stau1 regulates Dvl2 expression during myoblast differentiation
  Yamaguchi Yukio; Naiki Takahiro; Irie Kenji
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/417(1)/pp.427-432, 2012-01
  PubMed
• RNA-Binding Protein Khd1 and Ccr4 Deadenylase Play Overlapping Roles in the Cell Wall Integrity Pathway in Saccharomyces cerevisiae
  Ito Wataru; Li Xia; Irie Kaoru; Mizuno Tomoaki; Irie Kenji
  EUKARYOTIC CELL/10(10)/pp.1340-1347, 2011-10
  PubMed
• Stau1 negatively regulates myogenic differentiation in C2C12 cells
  Yamaguchi Yukio; Oohinata Remi; Naiki Takahiro; Irie Kenji
  GENES TO CELLS/13(6)/pp.583-592, 2008-06
• Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast
  Hasegawa Yuko; Irie Kenji; Gerber Andre P.
  RNA-A PUBLICATION OF THE RNA SOCIETY/14(11)/pp.2333-2347, 2008-11
  PubMed
• hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions
  Fukuda Toshiyuki; Naiki Takahiro; Saito Marie; Irie Kenji
  GENES TO CELLS/14(2)/pp.113-128, 2009-02

Books

• International Medical Science Course (2015年度国立台湾大学への10日間の派遣)
  大庭 良介; 須田恭之; 入江賢児
  Tsukuba Journal of Medical Science, 2016

Conference, etc.

• Remodeling of organelles for membrane traffic in meiosis.
  須田 恭之; 舘川宏之; 中野明彦; 入江賢児
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会 合同年次大会/2019-06-24--2019-06-26
• 出芽酵母の小胞体ストレス応答に関与するキナーゼ群の探索
  高田奈苗; 入江賢児; 水野 智亮
  酵母遺伝学フォーラム第５１回研究報告会/2018-09--2018-09
• 出芽酵母小胞体ストレス応答における転写因子Sfp1を介したリボソーム発現制御の生理学的意義
  高木亮輔; 入江賢児; 水野 智亮
  酵母遺伝学フォーラム第５１回研究報告会/2018-09--2018-09

Teaching

2020-04 -- 2020-08	Special Practice in Human Biology II	University of Tsukuba.
2020-10 -- 2021-02	Special Practice in Human Biology II	University of Tsukuba.
2020-10 -- 2021-02	Special Seminars in Human Biology II	University of Tsukuba.
2020-10 -- 2020-12	English Discussion and Presentation on Medical Sciences II	University of Tsukuba.
2020-04 -- 2020-08	Special Lectures in Human Biology II	University of Tsukuba.
2020-10 -- 2021-02	Special Research in Human Biology II	University of Tsukuba.
2020-04 -- 2020-08	Special Seminars in Human Biology I	University of Tsukuba.
2020-04 -- 2020-08	Special Seminars in Human Biology II	University of Tsukuba.
2020-04 -- 2020-08	Laboratory Training in Human Biology I	University of Tsukuba.
2020-10 -- 2020-12	Medical Molecular Biology	University of Tsukuba.

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(Last updated: 2019-07-08)