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Ookawa Keiko

Affiliation
Faculty of Medicine
Official title
Assistant Professor
URL
Research fields
Biomedical engineering/Biomaterial science and engineering
Research keywords
Medical Education
Biomedical Engineering
Tissue Engineering
医工学
Research projects
Microcirculatory physiology -- (current)/
Development and assessment of tissue-engineered artificial organs -- (current)/
組織工学的手法による未分化細胞から血管への選択的誘導とフェノタイプの安定発現2003 -- (current)Japan Society of for the Promotion of Science/基盤研究(C)1,600,000Yen
Career history
1986-04 -- 1988-03富士通株式会社 システムエンジニア（医療分野）
1991-10 -- 1993-03工業技術院機械技術研究所　科学技術庁科学技術特別研究員
1993-04 -- (current)筑波大学 講師
Academic background
-- 1984International Christian University Faculty of Liberal Arts 理学科Graduated
-- 1986University of Tsukuba Graduate School, Division of Medical Science 医科学専攻Completed
-- 1992University of Tsukuba Graduate School, Division of Medicine 生理系Completed
Degree
1986-03MSUniversity of Tsukuba
1992-03PhD (Medical Sciences)University of Tsukuba
Academic societies
-- (current)Japan Society for Cell Biology
-- (current)THE JAPAN SOCIETY FOR ARTIFICIAL ORGANS
-- (current)JAPANESE SOCIETY FOR MEDICAL AND BIOLOGICAL ENGINEERING
-- (current)JAPANESE SOCIETY FOR MICROCIRCULATION
Honors & Awards
2007Yoshimi Memorial T.M.P. Grant
2005日本バイオレオロジー学会論文賞
1993日本エム・イー学会 松尾賞
1992日本エム・イー学会ポスターコンペティション優秀賞
Articles
  • 円錐 : 平板型回転粘度計を用いた汎用性の高い抗血栓性材料のスクリーニング法
    古川 克子; 大川 敬子; 柳 健一; 牛田 多加志; 立石 哲也; 大...
    日本バイオレオロジー学会年会抄録集/18/pp.62-62, 1995-06
    CiNii
  • 腹膜播種性腫瘍モデルにおける腸間膜微小血管網の血流動態の解析
    柳 健一; 鈴木 俊繁; 大川 敬子; 大島 宣雄
    日本バイオレオロジー学会年会抄録集/19/pp.52-52, 1996-06
    CiNii
  • 血液有形成分の挙動のバイオメカニクス : 選択的可視化法による観察
    大島 宣雄; 柳 健一; 大川 敬子; 鈴木 俊繁; 夏井 裕昭
    日本バイオレオロジー学会年会抄録集/20/p.5, 1997-06
    CiNii
  • 代謝型人工肝臓の医工学的問題点
    大島宣雄; 大川敬子
    日本臨牀/43/p.2617-2621, 1985-01
  • ヒドロゲルで包理した肝細胞の凍結保存法確立のための予備的検討
    田村容子; 大川敬子; 岡崎さつき; 中西毅; 大島宣雄
    人工臓器/16/p.924-927, 1987-01
  • 回転円板型モジュールを用いた代謝型肝機能補助装置 (共著)
    大川敬子; 田村容子; 大島宣雄
    人工臓器/16/p.966-968, 1987-01
  • 回転円板型肝機能補助装置の性能評価
    柳健一; 大川敬子; 水野秀一; 大島宣雄
    人工臓器/18/p.1273-1276, 1989-01
  • Performance of a new type hybrid artificial liver support system using hepatocytes entrapped within a hydrogel (共著)
    Yanagi K; Ookawa K; Mizuno S; Ohshima N
    Trans Am Soc Artif Intern Organs/35(3)/pp.570-572, 1989-01
    PubMed
  • ずり応力に対する培養内皮細胞の反応
    佐藤正明; 大川敬子; Nerem RM; 大島宣雄
    脈管学/30/p.1153-1156, 1990-01
  • Emigration of activated leukocytes augments transvascular permeability in mesenteric venules of rat. (共著)
    Ookawa K; Sato M; Ohshima N
    in vivo/5/p.349-354, 1991-01
  • Changes in microstructure of cultured porcine aortic endothelial cells in the early stage after applying fluid-imposed shear stress.
    Ookawa K; Sato M; Ohshima N
    J Biomech/25(11)/pp.1321-1328, 1992-01
    PubMed
  • Platelet thrombi produced on cultured endothelial cells by the dye/light method. (共著)
    Sato M; Onohara M; Ookawa K; Ohshima N
    Biorheology/29/p.489-498, 1992-01
  • Morphological changes of endothelial cells after exposure to fluid-imposed shear stress : Differential responses induced by extracellular matrices
    Ookawa K; Sato M; Ohshima N
    Biorheology/30/p.131-140, 1993-01
  • Time course changes in cytoskeletal structures of cultured endothelial cells exposed to shear stress. (共著)
    Ookawa K; Sato M; Ohshima N
    Frontiers Biol Med Engng/5/p.127-131, 1993-01
  • 多孔質樹脂を担体とする肝実質・非実質細胞のcoculture
    三好浩稔; 柳健一; 大川敬子; 大島宣雄
    人工臓器/23/p.479-484, 1994-01
  • Kinetic analyses of the performance of a hybrid-type artificial liver support system utilizing isolated hepatocytes
    Ohshima N; Shiota M; Kusano H; Wada G; Tsunetsugu T; Ooka...
    Mat Sci Eng C/1/p.79-85, 1994-01
  • 微小循環動態の可視化によるshear stressの評価
    大川敬子; 大島宣雄
    現代医療/27/p.3527-3532, 1995-01
  • Flow visualization of the microcirculation in solid tumor tissues : Intravital microscopic observation of blood circulation by use of a confocal laser scanning microscope.
    Suzuki T; Yanagi K; Ookawa K; Hatakeyama K; Ohshima N.
    Frontiers Med Biol Engng/7/p.253-263, 1996-01
  • 経血管治療用カテーテルによる血管内皮傷害のin vitro評価システムの開発
    菅原理裕; 大川敬子; 大島宣雄
    人工臓器/27/p.514-518, 1998-01
  • Blood flow and leukocyte adhesiveness are reduced in the microcirculation of a peritoneal disseminated colon carcinoma
    Suzuki T; Yanagi K; Ookawa K; Hatakeyama K; Ohshima N.
    Ann Biomed Engng/26/p.803-811, 1998-01
  • Hepatocyte culture utilizing porous polyvinyl formal resin maintains long-term stable albumin secretion activity
    Miyoshi H; Ookawa K; Ohshima N.
    Journal of biomaterials science. Polymer edition/9(3)/pp.227-237, 1998-01
    PubMed
  • Especially Polymorphonuclear leulcocytes but also monomorphormclear leukocytes, roll spontaneously in veuules of intact rat skin : involvement of E-selectin
    oude Egbrink MGA; Janssen GHGW; Ookawa K; Slaaf DW; Renem...
    Journal of Investigative Dermatology/118/p.323-326, 2002-01
  • 管内流れの動態と内皮細胞の増殖能に及ぼすステントの形状の影響
    赤川英毅; 大川敬子; 大島宣雄
    J Jpn Soc Biorheology/19/p.142-151, 2005-01
  • Evaluation of polydimethylsiloxane scaffolds with physiologically-relevant elastic moduli: interplay of substrate mechanics and surface chemistry effects on　vascular smooth muscle cell response.
    Brown XQ; Ookawa K; Wong JY.
    Biomaterials/26/pp.3123-3129, 2005-01
  • Intravital microscopic observation of hemodynamic changes of vasa nervorum accampanying local heat stimulation
    Takagi K; Yamaguchi S; Ookawa K; Ohshima N
    Microcirc Ann/21/p.65-66, 2005-01
more...
Books
  • 粥状硬化の成因における流れの因子の役割ー培養血管内皮細胞を用いた検討
    大川 敬子
    1992-03
  • 活性化した白血球の細静脈への粘着と物質透過性
    佐藤正明; 大川敬子; 大島宣雄
    血液レオロジー最近の進歩（Medical View）, 1992-01
  • Effects of shear stress on cytoskeletal structure ad physiological functions of cultured endothelial cells.
    Ohshima N; Ookawa K
    Cell Mechanics and Cellular Engineering (Springer-Verlag, New York), 1994-01
  • Development of a new shear flow apparatus to evaluate platelet-biomaterial interactions.
    Furukawa K; Ookawa K; Ushida T; Tateishi T; Ohshima N
    Advances in Biomaterial Science 1, 1997-01
  • Hepatocyte culture utilizing porous polyvinyl formal resin maintains long-term stable albumin secretion activity.
    Miyoshi H; Ookawa K; Ohshima N
    Polymer for Tissue Engineering (VSP B.V., Utrecht), 1998-01
  • Biomechanical considerations of the design of endovascular stents : effect of coil-pitch on intraluminal flow movement
    Akagawa E; Ookawa K; Ohshima N
    Tissue Engineering for Therapeutic Use 6 (Elsevier Science), 2002-01
Intellectural property rights
  • Stent structure to gain a sufficient luminal opening in tubalar organs
    大川 敬子
Teaching
2018-10 -- 2018-12Science of Medical InformationUniversity of Tsukuba.
2018-10 -- 2019-02Dissertation in Medical SciencesUniversity of Tsukuba.
2018-10 -- 2019-02Internship IUniversity of Tsukuba.
2018-10 -- 2019-02Internship IIUniversity of Tsukuba.
2018-10 -- 2019-02Seminar on Basic Medical SciencesUniversity of Tsukuba.
2018-10 -- 2019-02Advanced Exercise on Public HealthUniversity of Tsukuba.
2018-04 -- 2018-08Dissertation in Medical SciencesUniversity of Tsukuba.
2018-04 -- 2018-08Internship IUniversity of Tsukuba.
2018-04 -- 2018-08Internship IIUniversity of Tsukuba.
2018-04 -- 2018-08Seminar on Basic Medical SciencesUniversity of Tsukuba.
more...

(Last updated: 2018-05-25)