Kato Kosuke

Affiliation

Faculty of Medicine

Official title

Assistant Professor

Research fields

Molecular biology

Research projects

クロマチン制御因子TAF-Iによるヒトテロメアの構造と機能の制御機構	2018-04 -- 2021-03	加藤広介	Japan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research(C)	4,420,000Yen
新規の遺伝子治療に向けた人工ヌクレアーゼとクロマチンの機能ダイナミクス研究	2017-04 -- 2019-03	加藤広介	独立行政法人　日本学術振興会/二国間交流事業共同研究
ヒストンH1ユビキチン化によるゲノム安定性制御機構	2015-04 -- 2016-03	加藤　広介	日本学術振興会/若手研究（B)	3,770,000Yen
ヒストンＨ１ユビキチン化によるゲノム安定性制御機構	2014-04 -- 2015-03	加藤　広介	Japan Society for the Promotion of Science/若手研究(B)	3,770,000Yen

Academic societies

-- (current)

The Molecular Biology Society of Japan

Articles

• Jdp2-deficient Granule Cell Progenitors in the Cerebellum Are Resistant to ROS-mediated Apoptosis Through xCT/Slc7a11 Activation
  Ku Chia-Chen; Wuputra Kenly; Kato Kosuke; Lin Wen-Hsin; P...
  Scientific Reports/10(1), 2020-03
  PubMed
• Mitotic phosphorylation of CCCTC-binding factor (CTCF) reduces its DNA binding activity
  Sekiya Takeshi; Murano Kensaku; Kato Kohsuke; Kawaguchi A...
  FEBS open bio, 2017-01
• Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor
  Sekiya Takeshi; Kato Kohsuke; Kawaguchi Atsushi; Nagata K...
  Scientific reports, 2019-01
• Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor
  Sekiya Takeshi; Kato Kohsuke; Kawaguchi Atsushi; Nagata K...
  Scientific reports, 2019-01
• Assembly and remodeling of viral DNA and RNA replicons regulated by cellular molecular chaperones.
  Sekiya Takeshi; Hu Yifan; Kato Kohsuke; Okuwaki Mitsuru; ...
  Biophysical Reviews, 2018-04
• Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor
  Sekiya Takeshi; Kato Kohsuke; Kawaguchi Atsushi; Nagata K...
  Scientific reports/9(1)/p.329, 2019-01
  PubMed Tsukuba Repository
• Histone H1 chaperone activity of TAF-I is regulated by its subtype-dependent intramolecular interaction
  Kajitani Kaori; Kato Kosuke; Nagata Kyosuke
  Genes Cells, 2017-04
• Mitotic phosphorylation of CCCTC-binding factor (CTCF) reduces its DNA binding activity
  Sekiya Takeshi; Murano Kensaku; Kato Kohsuke; Kawaguchi A...
  FEBS open bio/7(3)/pp.397-404, 2017-03
  PubMed Tsukuba Repository
• Glucocorticoids facilitate the transcription from the human cytomegalovirus major immediate early promoter in glucocorticoid receptor- and nuclear factor-I-like protein-dependent manner
  Inoue-Toyoda Maki; Kato Kosuke; Nagata　Kyosuke; Yoshikaw...
  Biochem Biophys Res Commun, 2015-02
• Involvement of Nucleocytoplasmic Shuttling of Yeast Nap1 in Mitotic Progression
  Mary Miyaji-Yamaguchi; Kohsuke Kato; Ryosuke Nakano; Tomo...
  Molecular and Cellular Biology/23(18)/p.6672-6684, 2003-01
• Gene silencing and histone modification by JDP2, a repressor that binds to the AP-1 regulatory sequence, during the differentiation of F9 embryonic carcinoma cells
  Bingbing Liu; Takahito Yamasaki; Chunyuan Jin; Koji Nakad...
  Current Topics in Genetics/1/p.1-17, 2005-01
• Assembly and Disassembly of Nucleosome Core Particles Containing Histone Variants by Human Nucleosome Assembly Protein I
  Mitsuru Okuwaki; Kohsuke Kato; Hideto Shimahara; Shin-ich...
  Molecular and Cellular Biology/25(23)/p.10639-10651, 2005-01
• Assaying of nucleosome-assembly and histone acetyltransferase-inhibition (HAT-inhibition)
  Takehide Murata; Chunyuan Jin; Kohsuke Kato; Takahito Yam...
  Nature Protocols/p.DOI: 10.1038/nprot.2007., 2007-01
• Involvement of Template Activating Factor-I as a chaperone in linker histone dynamics
  Kohsuke Kato; Mitsuru Okuwaki; Kyosuke Nagata
  Journal of Cell Science/124(19)/pp.3254-3265, 2011-10
  PubMed
• Histone acetylation-independent transcription stimulation by a histone chaperone
  Kato Kohsuke; Miyaji-Yamaguchi Mary; Okuwaki Mitsuru; Nag...
  NUCLEIC ACIDS RESEARCH/35(3)/pp.705-715, 2007-02
  PubMed
• Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones
  Okuwaki Mitsuru; Kato Kohsuke; Nagata Kyosuke
  GENES TO CELLS/15(1)/pp.13-27, 2010-01
• Synergistic action of MLL, a TRX protein with template activating factor-I, a histone chaperone
  Shimoyama T; Kato K; Miyaji-Yamaguchi M; Nagata K
  FEBS LETTERS/579(3)/pp.757-762, 2005-01
  PubMed
• Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I
  Okuwaki M; Kato K; Shimahara H; Tate S; Nagata K
  MOLECULAR AND CELLULAR BIOLOGY/25(23)/pp.10639-10651, 2005-12
  PubMed
• Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2
  Jin CY; Kato K; Chimura T; Yamasaki T; Nakade K; Murata T...
  NATURE STRUCTURAL & MOLECULAR BIOLOGY/13(4)/pp.331-338, 2006-04

Books

• ヒストン/酸性分子シャペロンTAF-Iによるクロマチンからの転写制御機構
  加藤 広介
  2007-07
• クロマチンと遺伝子機能制御
  加藤 広介
  2003-01
• 細胞核の世界
  加藤 広介
  蛋白質核酸酵素・共立出版, 2006-11
• 転写因子・転写制御キーワードブック
  加藤 広介
  2006-01
• DNA Structure, Chromatin and Gene Expression
  加藤 広介
  2006-01
• 転写制御とエピジェネティクス‐ゲノムデコードに向けて‐
  加藤 広介
  2008-12
• 細胞核‐遺伝情報制御と疾患-
  加藤 広介
  実験医学・羊土社, 2009-11
• 目的別で選べるタンパク質発現プロトコール
  加藤 広介
  実験医学別冊・羊土社, 2010-04

Conference, etc.

• ヒストンH1シャペロンTAF-Iの分子内相互作用による活性制御機構
  Kajitani Kaori; Kato Kosuke; Kyosuke Nagata
  BMB2015/2015-12-01--2015-12-04
• ヒストンH1ユビキチン化によるG1-S遺伝子群の転写制御
  Kato Kosuke; Kyosuke Nagata
  BMB2015/2015-12-01--2015-12-04
• TAF-Iによるアデノウイルスコア複合体及び細胞性クロマチンの構造変換機構
  鍛谷　香織; 加藤広介; 永田　恭介
  第2回感染コンピテンシー若手研究会～ウイルス研究者の"新リベラルアーツ”～/2015-07-17--2015-07-18
• Involvement of histone H1 ubiquitination in post replicative chromatin maintenance
  加藤 広介
  Melbourne, Australia/2014-02-19--2014-02-22
• ユビキチン化によるヒストンH1の機能制御
  加藤 広介
  第31回　染色体ワークショップ/第12回　核ダイナミクス研究会/2013-11-25--2013-11-27
• In　cellulo　analysis　of　parvovirus-mediated　changes　of　nuclear　envelope　integrity　by real time microscopy.
  Snoussi Kenza; Kawaguchi Atsushi; Kato Kohsuke; Wodrich H...
  Leading Graduate Schools International Conference/2013-10-02--2013-10-04

Teaching

2020-10 -- 2021-02	Internship II	University of Tsukuba.
2020-04 -- 2020-08	Internship II	University of Tsukuba.
2020-10 -- 2021-02	Basic Experiments in Human Biology	University of Tsukuba.
2020-04 -- 2020-08	Seminar on Basic Medical Sciences	University of Tsukuba.
2020-10 -- 2021-02	Seminar on Basic Medical Sciences	University of Tsukuba.
2020-08 -- 2020-09	Clinical Microbiology	University of Tsukuba.
2020-10 -- 2020-12	Virology	University of Tsukuba.
2020-04 -- 2020-08	Internship I	University of Tsukuba.
2020-10 -- 2021-02	Internship I	University of Tsukuba.
2020-09 -- 2020-09	Practice of Virology	University of Tsukuba.

more...

Talks

• ヒストンH1結合因子によるクロマチン動態制御機構
  加藤 広介
  第10回　核ダイナミクス研究会/2011-10-27
• TAF-I is a linker histone chaperone in the mammalian somatic cell nucleus
  加藤 広介
  BMB2010/2010-12-07
• TAF-I, a novel somatic linker histone chaperone, is involved in chromatin dynamics
  加藤 広介
  9th EMBL Conference Transcription and Chromatin/2010-08-29

Other activities

2017-09 -- 2017-09

TGSW2017　セッションオーガナイザー（Transboader Networking in Human Biology)

(Last updated: 2020-05-28)