Kaneko Shin

Affiliation
Institute of Medicine
Official title
Professor
Research fields
General internal medicine (including psychosomatic medicine)
Cell biology
Research keywords
Gene Therapy
Cell Therapy
Clinical Hematology
Stem cell biology
Research projects
Clinical gene therapy of hematological malignancies1998 -- (current)/
Academic background
-- 1995University of Tsukuba Faculty of Medicine
-- 2002University of Tsukuba Graduate School, Division of Medicine Homatology, Immunology
Degree
Doctor(Medicine)University of Tsukuba
Academic societies
-- (current)The Japanese Cancer Association
-- (current)日本がん免疫学会
-- (current)THE JAPANESE SOCIETY OF HEMATOLOGY
-- (current)JAPANESE SOCIETY FOR IMMUNOLOGY
-- (current)THE JANPANESE SOCIETY OF INTERNAL MEDICINE
-- (current)日本免疫治療学会
-- (current)THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
Honors & Awards
2001The Young Investigater's award of Japanese Society of Hematology
2001日本血液学会奨励賞
Articles
  • 同種iPS細胞から誘導したCAR-T細胞療法の開発
    金子 新
    The Japanese journal of clinical hematology/63(10)/pp.1454-1459, 2022-10
  • iPS細胞を用いたがん免疫療法について
    金子 新; 河合 洋平
    BIO EX-press/pp.22-27, 2022-12
  • 人工胸腺オルガノイドからのCAR-T細胞の分化
    金子 新; 早稲田　真澄
    実験医学・増刊/41(2)/pp.101-106, 2023-02
  • iPS細胞を使用した免疫療法の開発
    金子 新; 柴田　翔
    血液内科/85(6)/pp.883-888, 2022-12
  • Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells
    金子 新; Ueda T. et al.
    NATURE BIOMEDICAL ENGINEERING/7(1)/pp.24-37, 2022-12
  • 同種iPS細胞から誘導したCAR-T療法の開発
    金子 新
    The Japanese journal of clinical hematology/63(10)/pp.1454-1460, 2022-10
  • iPS細胞を用いた免疫療法
    金子 新
    必修！腫瘍免疫学/pp.113-116, 2022-04
  • Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in an animal model
    Kaneko Shin; Ishikawa A Waseda M Ishii T Kaneko K. M ...
    Cell to Cells/27(9)/pp.549-558, 2022-07
  • Successful organoid-mediated generation of iPSC-derived CAR-T cells
    Kaneko Shin
    CELL STEM CELL/29(4)/pp.493-+, 2022-04
  • Modeling of Tumor-on-a-Chip using HLA edited iPS cell-derived vascular endothelial cells for cancer immune cell therapy
    Mishima Yuta; Kaneko Shin; Torisawa Yu-suke
    CANCER SCIENCE/113(1:SI), 2022-02
  • iPS細胞のがん免疫療法への応用
    金子 新
    CLINICAL ONCOLOGY/29(2)/pp.188-193, 2022-02
  • The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte derived iPS cells
    Kaneko Shin
    Communications biology/p.694, 2021-06-07
    PubMed
  • Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells
    金子 新
    NATURE BIOMEDICAL ENGINEERING/(5)/pp.429-440, 2021-05-17
  • Kaneko S, Nagata M, Takemura H, Yuhara T, Akama T, Suzuki H, Yamane K, and Kashiwagi H. Gelatious transformation of bone marrow with pancytopenia in an emaciated patient with systemic lumpus erythematosus.
    金子 新
    Jpn J Rheumatol/8/p.167-173, 1998
  • Yasukawa M, Ohminami H, Kaneko S, Yakushijin Y, Nishimura Y, Inokuchi K, Miyakuni t, Nakao S, Kishi K, Kubonishi I, Dan K, and Fujita S. CDA(+) cytotoxic T-cell clones spesific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner.
    金子 新
    Blood/(92)/p.3355-3361, 1998
  • 金子　新、中内　啓光．動員造血血幹細胞移植後の増殖分化． 血液・免疫・腫瘍
    金子 新
    *EMPTY*/(4)/p.49-55, 1999
  • 金子　新、小野寺　雅史、中内　啓光．造血細胞を用いた遺伝子治療の現況． 組織培養工学
    金子 新
    *EMPTY*/(25)/p.442-446, 1999
  • Ohminami H, Yasukawa M, Kaneko S, Yakushijin Y, Abe Y, Kasahara Y, Ishida Y, and Fujita S. Fas-independent and nonapoptotic cytotoxicity mediated by a human CD4(+) T-cell clone directed against an acute myelogenous leukemia-associated DEK-CAN fusion peptide.
    金子 新
    Blood/(93)/p.925-935, 1999
  • Yasukawa M, Hasegawa A, Sakai I, Ohminami H, Arai J, Kaneko S, Yakushijin Y, Maeyama K, Nakashima H, Arakaki, R, and Fujita S. Down-regulation of CXCR4 by human herpesvirus 6(HHV-6) and HHV-7.
    金子 新
    J.Immunol/(162)/p.5417-5422, 1999
  • 金子　新、中内　啓光．造血幹細胞の純化と分化・増殖機構． 現代医療
    金子 新
    *EMPTY*/(32)/p.2603-2608, 2000
  • Kaneko S, Onodera M, Fujiki Y, Nagasawa T, and Nakauchi H. The simplified retroviral vector GCsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in non-obese diabetic/severe combined immunodeficiency mice.
    金子 新
    Hum Gene Ther/(12)/p.35-44, 2001
  • 金子　新、中内　啓光．第4章　組織幹細胞の可塑性と再生医学．横田崇編．再生医学がわかる　第1版．東京：
    金子 新
    羊土社/p.47-56, 2002
  • 金子　新、中内　啓光．幹細胞の可塑性． 血液・腫瘍科
    金子 新
    *EMPTY*/(44)/p.471-476, 2002
  • Suzuki A, Zheng YY, Kaneko S, Onodera M, Fukao K, Nakauchi h, and Taniguchi H. Clonal indentification and Characterization of self-renewing pluripotent stem cells in the developing liver.
    金子 新
    J Cell Biol/(156)/p.173-184, 2002
  • Iwama A, Osawa M, Hirasawa R, Uchiyama N, Kaneko S, Onodera M, Shibuya K, Shibuya A, Vinson C, Tenen DG, Nakauchi H. Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU. 1 transcription factors in Langerhans cell commitment.
    金子 新
    J Exp Med/(195)/p.547-558, 2002
  • more...
Teaching
2023-04 -- 2023-08Seminar in Internal Medicine IUniversity of Tsukuba.
2023-10 -- 2024-02Practice in Internal Medicine IIUniversity of Tsukuba.
2023-04 -- 2023-08Lecture and Discussion in Internal Medicine IUniversity of Tsukuba.
2023-10 -- 2024-02Lecture and Discussion in Internal Medicine IIUniversity of Tsukuba.
2023-10 -- 2024-02Seminar in Internal Medicine IIUniversity of Tsukuba.
2023-04 -- 2023-08Practice in Internal Medicine IUniversity of Tsukuba.
2022-04 -- 2022-08Lecture and Discussion in Clinical Pathophysiology IUniversity of Tsukuba.
2022-10 -- 2023-02Seminar in Internal Medicine IIUniversity of Tsukuba.
2022-10 -- 2023-02Lecture and Discussion in Internal Medicine IIUniversity of Tsukuba.
2022-04 -- 2022-08Seminar in Internal Medicine IUniversity of Tsukuba.
more...
Talks
  • 遺伝子改変による高機能型iPS由来CAR-T（予定）
    金子 新
    第22回日本再生医療学会総会/2023-03-25
  • がん治療のための iPS 細胞由来免疫細胞の製造と臨床試験
    金子 新
    再生医療実現拠点ネットワークプログラム　iPS細胞研究中核拠点　第5回情報交換会/2023-02-15
  • アロジェニックCAR-T
    金子 新
    第7回再生医療産官学連携シンポジウム/2023-01-26
  • 免疫再生研究と産業化への取り組み
    金子 新
    再生医療を推進する議員の会/2022-12-15
  • DEVELOPMENT OF IPSC-DERIVED FUNCTIONAL LYMPHOCYTES FOR IMMUNE CELL THERAPY
    Kaneko Shin
    2022 Symposium on Cell Manufacturing and Commercialization/2022-11-19
  • iPS細胞からのT細胞再生と同種CAR-T療法、TCR-T療法の開発
    金子 新
    第84回日本血液学会学術集会/2022-10-15
  • iPS細胞を用いたがん免疫再生療法の研究
    金子 新
    メディア勉強会/2022-09-15
  • CD8 killer T cells and NK cells from iPSC for cancer immunotherapy
    金子 新
    第28回日本遺伝子細胞治療学会学術集会/2022-07-16
  • iPS cell-based technologies for allogeneic cancer immunotherapy
    Kaneko Shin
    The 1st Catholic International Symposium for Advenced Regenerative Medicine/2022-07-08
  • iPS由来T細胞、NK細胞を用いた新たながん治療～基礎から最前線まで
    金子 新
    SBI証券講演会/2022-06-24
  • Development of CAR-T cell therapy using allogeneic induced pluripotent stem cells
    Kaneko Shin
    ISSCR: Workshop Clinical Translation/2022-06-15
  • Induced pluripotent stem cell derived killer cell for CAR-based cancer immunotherapy
    Kaneko Shin
    Mayo Clinic Honorarium Lecture/2022-06-11
  • iPS細胞から誘導したCD8キラーT細胞とNK細胞の特性
    金子 新
    第19回日本免疫治療学会学術集会/2022-05-22
  • iPS細胞を用いた免疫再生治療の開発
    金子 新
    第1回EPU先端医療セミナー/2022-05-20
  • iPS細胞からのキラーT細胞、NK細胞の再生と臨床応用
    金子 新
    第44回日本造血・免疫細胞療法学会総会/2022-05-13
  • Development of iPSC-derived Immune Cells For Cancer Immunotherapy
    Kaneko Shin
    ISCT 2022/2022-05-05

(Last updated: 2023-05-16)