MURATANI Masafumi

Affiliation
Institute of Medicine
Official title
Professor
ORCID
0000-0002-0276-8000
URL
Email
%HPM<O<ID^miH?gONPFP=<g<>gEK
Office
Department of Genome Biology
Phone
029-853-7645
Fax
029-853-3333
Research fields
Genome biology
Molecular biology
Research keywords
Space Life Sciences
Laboratory automation
Gene regulation
Epigenome, epigenetics
Genome, genomics
Research projects
Astronaut Digital Twins: the application of iPS cells and artificial intelligence for personalized space medicine2024-01 -- (current)MURATANI MasafumiJapan Aerospace Exploration Agency (JAXA)/Flagship mission in KIBO
Characterization of cell-free mitochondrial and extracellular vesicle components in plasma for understanding space environment responses2023-04 -- 2026-03MURATANI MasafumiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (B)18,070,000Yen
Space life science research to predict the future of life on and beyond Earth2022-06 -- 2023-03Masafumi MURATANIUniversity of Tsukuba/Tsukuba Innovation Arena "KAKEHASHI"1,000,000Yen
Cell-free DNA and RNA epigenome study to investigate space environment and ageing stress responses2020-11 -- 2023-03MURATANI MasafumiJapan Society for the Promotion of Science/Grant-in-Aid for JSPS Fellows2,200,000Yen
Plasma cell-free DNA and RNA analysis of astronauts for evaluation of space environmental responses2020-04 -- 2023-03MURATANI MasafumiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (B)17,420,000Yen
宇宙滞在中の液体生検による血漿中核酸のゲノム・エピゲノム解析2015-04 -- (current)MURATANI MasafumiJapan Aerospace Exploration Agency (JAXA)/ライフサイエンスおよび宇宙医学分野の国際宇宙ステーション利用実験3,000,000Yen
癌特異的クリプティック遺伝子プロモーターの転写サイクルプロファイリング2015-04 -- 2017-03MURATANI MasafumiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)11,440,000Yen
Integrative genome and epigenome analysis of non-coding regulatory regions in lung cancer2015-04 -- 2019-03MURATANI MasafumiJapan Society for the Promotion of Science/Grant-in-Aid for Young Scientists (A)23,270,000Yen
Integrated understanding of plastic alteration of vestibular system and countermeasures for adaptive disorder2015-07 -- 2020-03MORITA HironobuJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)14,360,000Yen
マウスを用いた宇宙環境応答の網羅的解析2014-02 -- (current)TAKAHASHI SatoruJapan Aerospace Exploration Agency (JAXA)/「きぼう」の科学利用 (分担者)
Career history
2019-03 -- (current)筑波大学医学医療系教授
2024-12 -- (current)Impact Science Co. Ltd.Reserach Advisor
2018-12 -- (current)Robotic Biology Institute Inc.Research Advisor
2018-12 -- (current)LSI Medience CorporationGenome Science Reserach CenterSenior Research Fellow
2014-02 -- 2019-02University of TsukubaFaculty of MedicineAssociate Professor
2008-07 -- 2014-01Genome Institute of SingaporeResearch Associate
2006-09 -- 2008-07Human Frontier Science ProgramLong-term Fellow
2006-04 -- 2006-09日本学術振興会海外特別研究員
2005-09 -- 2008-07Cancer Research UK, London Research InstituteResearch Fellow
2005-04 -- 2005-09Cold Spring Harbor LaboratoryPostdoc
Academic background
2000-08 -- 2005-04Watson School of Biological Sciences, Cold Spring Harbor Laboratyory
1996-04 -- 2000-03University of Tsukuba College of Biological Sciences Human Biology Course
Degree
2005-04Ph.D.Watson School of Biological Sciences, Cold Spring Harbor Laboratory
2000-03B.Sc.University of Tsukuba
Academic societies
2023-08 -- (current)American Geophysical Union
2023-01 -- (current)Sigma Xi
2021-12 -- (current)GeneLab Analysis Working Group
2020-10 -- (current)International Standards for Space Omics Processing (ISSOP)
2020-06 -- (current)American Society for Gravitational and Space Research
2018-08 -- (current)日本宇宙放射線研究会
2018-08 -- (current)日本宇宙生物科学会
2017-12 -- 2019-11Human Genome Organization
Honors & Awards
1999-07Atsushi Kitaueda Memorial FundTravel support for Cold Spring Harbor Laboratory Undergraduate Research Program
1998-06Atsushi Kitaueda Memorial FundTravel support for summer internship at Rockefeller University
Articles
Books
  • 第6章 データ解析時のファイルのフォーマット
    橋本 幸枝; 関根 郁夫; 村谷 匡史
    がんゲノム医療 結果報告書の読み方と患者への伝え方〜エキスパートパネルの実際〜/医学と看護社/pp.40-47, 2020-05
  • がんゲノム医療結果報告書の読み方と患者への伝え方〜エキスパートパネルの実際
    野口 惠美子; 関根郁夫; 村谷匡史; 千葉　滋
    株式会社医学と看護社, 2020-06
  • 臨床情報とがんゲノム医療の適応
    鈴木 英雄; 関根郁夫; 村谷匡史; 千葉滋; 野口恵美子; 池見亜也子
    医学と看護社, 2020
Conference, etc.
  • Astronaut Digital Twins: the application of induced pluripotent stem cell-based assays and artificial intelligence for personalized space health
    MURATANI Masafumi; ADJAYE James; AKIYAMA Taishin; BEHE...
    Human Research Program Investigators' Workshop/2025-01-28--2025-01-31
  • Comprehensive DNA and RNA analysis of plasma fractions obtained from astronauts in JAXA Cell-Free Epigenome Study
    HUSNA Nailil; MURATANI Masafumi
    Human Research Program Investigators' Workshop/2025-01-28--2025-01-31
  • Integrative Analysis of Mouse Space Flight Transcriptome Datasets Highlights Epigenetic Mechanisms behind “Throwback Phenotype” in Space
    HUSNA Nailil; MURATANI Masafumi
    Astrobiology and the future of life meeting/2024-10-16--2024-10-18
  • Implications of Space Phenotypes and Multigenerational Effects of Terrestrial Organisms for Future Prediction of Life on Earth and Beyond
    MURATANI Masafumi; SADIER Alexa; RUDOLF Agata
    Astrobiology and the future of life meeting/2024-10-16--2024-10-18
  • Integration of multi-omics approaches in space life science
    MURATANI Masafumi
    VII Space Resources Conference/2024-05-23--2024-05-24
  • Space Phenotypes of Terrestrial Life Under Microgravity Aboard the International Space Station Highlight Conceptual Link Between Evolutional Biology and Astrobiology
    MURATANI Masafumi; SADIER Alexa
    AbSciCon 2024/2024-05-05--2024-05-10
  • How to build an alien: exploring the evolutionary rules of multicellular life
    SADIER Alexa; MURATANI Masafumi
    AbSciCon 2024/2024-05-05--2024-05-10
  • Analysis of the plastic changes induced in the soleus muscle under microgravity conditions
    諒介 辻; 林 卓杜; 工藤 崇; 藤田 諒; 濱田 理人; 岡田 理沙; 村谷 匡史; 芝 大; ...
    74th International Astronautical Congress/2023-10
  • 微小重力環境を利用した新規骨格筋制御遺伝子の探索
    林 卓杜; 藤田 諒; 岡田 理沙; 濱田 理人; 布施谷 清香; 金井 真帆; 井上 由理; 定木 駿弥; 村谷...
    第9回(2023年度)日本筋学会学術集会/2023-08
  • 月重力1/6 gは微小重力による筋萎縮を抑制するが、筋線維タイプの変化は抑制しない
    林 卓杜; 藤田 諒; 岡田 理沙; 濱田 理人; 布施谷 清香; 金井 真帆; 井上 由理; 定木...
    第70回(2023年度)日本実験動物学会総会/2023-05-24--2023-05-26
  • Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
    定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
    50TH EUROPEAN MUSCLE CONFERENCE/2023-09
  • 速筋線維を制御する大Maf群転写因子の解析
    定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
    第10回サルコペニア・フレイル学会大会/2023-11
  • Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
    定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
    第31回(2023年度)日本運動生理学会大会/2023-08
  • 大Maf群転写因子はtype IIb筋線維を制御する主要な因子である
    定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
    第70回(2023年度)日本実験動物学会総会/2023-05-24--2023-05-26
  • SNRNP200は姉妹染色分体の接着と中心体周期の制御に機能する
    甲田愛奈; 加藤かざし; 柳下 玲奈; 宇田川里奈; 林優樹; 村谷 匡史; 金俊達; 木村 圭志
    第46回　日本分子生物学会年会/2023-12-06--2023-12-08
  • Space Radiation Damage Rescued by Inhibition of Key Spaceflight Associated miRNAs
    McDonald J. Tyson; Kim JangKeun; Farmerie Lily; Johnso...
    American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18
  • Spaceflight induces changes in gene expression profiles linked to insulin and estrogen signaling (IN57)
    Mathyk Begum; Tabetah Marshall; Karim Rashid; Zaksas ...
    American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18
  • Cosmic Kidney Disease: A Pan-Omic investigation of the health consequnce of a trip to Mars and back
    Siew Keith; Nestler Kevin A.; Nelson Charlotte; D'Ambr...
    American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18
  • Space, Adaptation and Evolution: an open science theme for predicting the future of life on and beyond Earth
    Muratani Masafumi; Sadier Alexa
    12th Annual International Space Station Research and Development Conference/2023-07-31--2023-08-03
  • DONSONおよびsororinのpre-mRNAの適切なスプライシングを介した細胞分裂期制御の解明
    加藤　かざし; 柳下 玲奈; 林　優樹; 村谷 匡史; 金 俊達; 木村　圭志
    第45回日本分子生物学会年会/2022-11-30--2022-12-2
  • 宇宙研究からアプローチする適応・進化の理解と地球生命の未来予測
    村谷 匡史
    第45回日本分子生物学会年会,ワークショップ,クロマチン潜在能に働きかけるエピゲノムと核内構造体/2022-12-01
  • Identification and validation of multi-omics frailty biomarkers in human spaceflight
    Camera A; Galsinh AS; Kim JK; Barker RJ; Enguita FJ; MN ...
    American Society for Gravity and Space Research (ASGSR) Annual Conference 2022/2022-11-09--2022-11-12
  • Molecular characterization of space environment responses in internal tissues by cell-free DNA and RNA analysis of plasma samples collected from six astronauts.
    Rutter Lindsay; Husna Nailil; Fujita Shin-ichiro; Saito ...
    American Society for Gravity and Space Research (ASGSR) Annual Conference 2022/2022-11-09--2022-11-12
  • 速筋線維の形成に不可欠な新規制御因子である大Maf転写因子の機能解析
    定木駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 栄治; 久野 朗広...
    日本分子生物学会年会/2022-12
  • 月重力による骨格筋可塑性への影響
    林 卓杜; 藤田 諒; 岡田理沙; 濱田理人; 布施谷清香; 金井真帆; 井上由理; 定木駿弥; 村谷匡史; 蕨栄治; 工藤 崇...
    第95回日本生化学会大会/2022-11-09--2022-11-11
  • more...
Teaching
2024-04 -- 2024-08Special Research in Humanics IIIaUniversity of Tsukuba.
2024-10 -- 2025-02Special Seminars in Humanics IIIbUniversity of Tsukuba.
2024-10 -- 2025-02Basic Experiments in Human BiologyUniversity of Tsukuba.
2024-04 -- 2024-08Special Seminars in Human Biology IUniversity of Tsukuba.
2024-10 -- 2025-02Special Lectures in Humanics IIIbUniversity of Tsukuba.
2024-04 -- 2024-08Special Lectures in Humanics IIIaUniversity of Tsukuba.
2024-04 -- 2024-08Special Seminars in Humanics IIIaUniversity of Tsukuba.
2024-10 -- 2025-02Special Seminars in Human Biology IIUniversity of Tsukuba.
2024-10 -- 2025-02Special Lectures in Human Biology IIUniversity of Tsukuba.
2024-10 -- 2025-02Special Research in Human Biology IIUniversity of Tsukuba.
more...
Other educational activities
2022-08 -- (current)Virtual Summer Course 2022Faculty of Pharmacy Universitas Indonesia
2018-01 -- 2018-01Bioinformatics Course筑波大学、Biotechnology Center, Ho Chi Minh City, Vietnam
2017-02 -- 2017-02Bioinformatics Course筑波大学、Biotechnology Center, Ho Chi Minh City, Vietnam
2016-01 -- 2016-01Molecular Biology Course筑波大学、Science University, Ho Chi Minh City, Vietnam
2016-10 -- 2016-10出張講義麗澤高校
2015-11 -- 2015-11初級者向けインフォマティクス講習会新学術領域「転写サイクル」
2015-09 -- 2015-09インフォマティクス講習会JAXAプロジェクト研究者
Talks
  • Space life science research to predict the future of life on and beyond Earth
    村谷 匡史
    GeneLab Analysis Working Group Symposium 2022/2022-06-30
  • 網羅的遺伝子診断の方向性－ NGS次世代遺伝子解析と病理検査 －
    Muratani Masafumi
    第7回病理技術向上講座/2018-02-13--2018-02-13
  • 微量検体ゲノム・エピゲノム解析の環境ストレス研究への応用
    村谷 匡史
    第14回日本予防医学会学術総会/2016-06-18--2016-06-19
  • 臨床検体のゲノム・エピゲノム統合解析で探る疾患メカニズム
    村谷 匡史
    第34回分子病理学研究会　神戸シンポジウム/2015-07-25--2015-07-26
  • Ectopic induction of developmental gene regulatory network by cryptic promoters in gastric cancer
    村谷 匡史
    Joint International Symposium on TGF-β and Cancer/2015-01-12--2015-01-13
Professional activities
2023-09 -- (current)JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE科学者生活委員会
2023-09 -- (current)JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE長期構想委員会
2023-09 -- (current)JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE編集委員会
2023-09 -- (current)JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE理事
2023-01 -- (current)International Standards for Space Omics Processing (ISSOP)Co-Chair
2022-09 -- (current)The Japanese Society for Biological Sciences in Space若手研究者育成委員会
2022-09 -- (current)JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE代議員
2020-10 -- (current)International Standards for Space Omics Processing (ISSOP)Japan contact
2015-12 -- 2019-03新学術領域「宇宙に生きる」若手の会幹事会
University Management
2022-04 -- (current)医学医療系 施設・設備委員会委員
2016-04 -- (current)医学医療系 広報・情報委員会委員（生命医科学域）
2014-04 -- (current)つくばヒト組織バイオバンクセンター運営委員会委員

(Last updated: 2025-03-16)