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Nabekura Tsukasa

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Affiliation
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
Official title
Assistant Professor
Sex
Male
Birth date
1981-01
KAKEN ID
80550095
URL
Email
 
Phone
+81-29-853-3281
Research fields
Immunology
Research keywords
Natural killer cells
Immunological memory
Viral infection
Innate lymphoid cells
Immunology
Tumor immunology
Bone marrow transplant
Hematology
Research projects
Outstanding Young Immunology Researcher Award2021-01 -- 2021-12鍋倉宰特定非営利活動法人日本免疫学会/若手免疫学研究支援事業
ナチュラルキラー細胞の適応免疫特性獲得の制御機構の研究2020-04 -- 2021-03鍋倉宰国立大学法人筑波大学/令和2年度第1回　筑波大学研究基盤支援プログラム（Ｂタイプ）2,700,000Yen
急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割2018-04 -- 2021-03鍋倉宰The Naito Foundation/The Naito Grant for Fostering Scientific Full Bloom for the Next Generation6,000,000Yen
急性肝障害におけるDNAM-1の役割2018-04 -- 2020-03鍋倉宰Kato Memorial Bioscience Foundation/Grant-in-Aid2,000,000Yen
急性肝障害におけるDNAM-1の役割2018-04 -- 2019-03鍋倉宰Life Science Foundation of Japan/Grant-in-Aid1,000,000Yen
急性肝障害におけるDNAM-1 の役割2018-04 -- 2019-03鍋倉宰The Uehara Memorial Foundation/Grant-in-Aid2,000,000Yen
急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割2018-04 -- 2019-03鍋倉宰Kanae Foundation for the Promotion of Medical Science/The 46th Kanae grant1,000,000Yen
Identification of a master regulator of the differentiation of memory natural killer cells2017-04 -- 2020-03鍋倉 宰Japan Society for the Promotion of Science/Grant-in-Aid for Young Scientists(A)24,310,000Yen
慢性骨髄性白血病の再発に対する同種MHC反応性記憶ナチュラルキラー細胞を用いた新規ドナー養子免疫療法の開発2015-04 -- 2016-03鍋倉宰The Nakajima Foundation/Grant for Japanese young investigators4,000,000Yen
慢性骨髄性白血病再発に対するアロ反応性記憶ナチュラルキラー細胞を用いた免疫療法の開発2014-04 -- 2015-03鍋倉宰Friends of Leukemia Research Fund/Grant for young investigators500,000Yen
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Career history
2018-04 -- (current)University of Tsukuba Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) Assistant Professor
2014-03 -- 2018-03University of Tsukuba Life Science Center of Tsukuba Advanced Research Alliance (TARA) International Tenure-track Assistant Professor
2014-11 -- 2016-10University of California, San Francisco Department of Microbiology and Immunology, Lewis L. Lanier lab Specialist
2011-11 -- 2014-10University of California, San Francisco Department of Microbiology and Immunology, Lewis L. Lanier lab Postdoctoral Scholar
2008-04 -- 2011-10University of Tsukuba Graduate School of Comprehensive Human Sciences Postdoctoral fellow
Academic background
2005-04 -- 2008-03University of Tsukub Graduate School of Comprehensive Human Sciences Doctoral Program in Advanced Biomedical ApplicationsCompleted
Degree
2008-03Ph.D.University of Tsukuba
Academic societies
2012 -- (current)American Association of Immunologists
2003 -- (current)Japanese Society for Immunology.
Honors & Awards
2018-11Young Investigator Award in University of Tsukuba
2018-02BEST FACULTY MEMBER in University of Tsukuba
2017-12The Japanese Society of Immunology Young Investigator Award
2013-05AAI Trainee Abstract Award of IMMUNOLOGY 2013 Annual Meeting, The American Association of Immunologists
2012-11Postdoctoral Fellowship for Research Abroad of the Japan Society for the Promotion of Science (JSPS)
2011-11Postdoctoral Fellowship of the Uehara Memorial Foundation
2011-11Subsidy for Inter-Institute Researches of the Naito Foundation
2011-11Fellowship for Research Abroad of the Mochida Memorial Foundation for Medical and Pharmaceutical Research
2011-01Most Valuable Presenter in the 5th Tsukuba Medical Science Research Meeting
2011-01Best Paper Award in the 5th Tsukuba Medical Science Research Meeting
2008-04Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), PD
2008-03Graduate with Summa Cum Laude (3-year graduation in 4-year Doctoral Course), University of Tsukuba
2007-04Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), DC2
2006-01Cancer Research Fellowship for Graduate Students of Yasuda Medical Foundation
2005-03Best Paper Award in the Master’s Program in Medical Sciences, University of Tsukuba
2005-03Graduate with Summa Cum Laude (Best Paper Award in Master Course), University of Tsukuba
2003-03Graduate with Summa Cum Laude (Undergraduate Course), University of Tsukuba
Articles
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Books
  • An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2
    Nabekura Tsukasa
    2008-03
Conference, etc.
  • 1型自然リンパ球は急性肝障害において保護的な役割を持つ
    鍋倉 宰
    第8回筑波大学・東京理科大学合同リトリート/2020-11-14
  • Protective role of type 1 innate lymphoid cells in acute liver injury
    鍋倉 宰
    第29回東京免疫フォーラム/2021-03
  • Protective role of type 1 innate lymphoid cells in acute liver injury
    Nabekura Tsukasa
    The 48th Annual Meeting of the Japanese Society of Immunology/2019-12
  • Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus Infection
    Nabekura Tsukasa
    The 3rd International Conference of Innate Lymphoid Cel/2018-11
  • Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
    Nabekura Tsukasa
    RIKEN Center for Integrative Medical Sciences (IMS) – Japanese Society of Immunology (JSI) International Symposium on Immunology 2018/2018-06
  • 活性化受容体NKG2D はマウスサイトメガロウイルス感染時のナチュラルキラー細胞の増殖を促進するが、NKG2D シグナル単独では増殖に不十分である
    鍋倉 宰
    第6回筑波大学・東京理科大学合同リトリート/2018-03-17
  • Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
    Nabekura Tsukasa
    The 46th Annual Meeting of the Japanese Society of Immunology/2017-12
  • 共刺激分子DNAM-1はサイトメガロウイルス感染時に於ける記憶ナチュラルキラー分化に必要である
    鍋倉　宰; 金谷　穣; 渋谷　彰; Guo Fu; Gascoigne Nicholas ...
    第9回血液疾患・免疫療法学会学術集会/2017-09-30
  • 自己MHCクラスIを認識する活性化NK細胞受容体はNK細胞のエフェクター機能と記憶細胞分化を促進する
    鍋倉 宰
    第9回血液・疾患免疫療法学会学術集会/2017-09-30
  • Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    第26回東京免疫フォーラム/2017-03
  • Natural killer cell licensing and tolerance modulate differentiation of natural killer cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    The 44th Annual Meeting of the Japanese Society of Immunology/2015-11
  • DNAM-1 is required for expansion of effector NK cells and generation of memory NK cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    IMMUNOLOGY 2013 AAI Annual Meeting at Honolulu/2013-05
  • 活性化免疫受容体DNAM-1の急性肝GVHDの病態形成における重要な役割
    金谷　穣; 渋谷　和子; 阿部　史枝; 鍋倉　宰; 渋谷　彰
    第4回造血器腫瘍免疫療法研究会学術集会/2012-08-18
  • The role of CD155, a novel co-stimulatory molecule in CD4+ T cells, in contact dermatitis
    Yumi Kanemaru; Yuichi Takahashi; Yinan Wang; Aya Yoshioka...
    第40回　日本免疫学会総会・学術集会/2011-11
  • A critical role of DNAM-1 in the development of acute graft-versus-host disease
    Nabekura Tsukasa
    The 5th Tsukuba Medical Science Research Meeting/2011-01
  • Identification and characterization of the poliovirus receptor(CD155)as a novel co-stimulatory molecule in CD4+ T cells.
    Yamashita Y; Wang Y; Yoshioka A; Nabekura T; Tahara-Hanao...
    第14回国際免疫学会議/2010-08-27
  • Identification and characterization of the poliovirus receptor(CD155)as a novel co-stimulatory molecule in CD4+ T cells.
    Yamashita Y; Wang Y; Yoshioka A; Nabekura T; Tahara-Hanao...
    第14回国際免疫学会議/2010-08-26
  • Novel prophylactic and therapeutic approaches to GVHD with a monoclonal antibody against DNAM-1
    Nabekura Tsukasa
    The 2nd Society of Immunotherapy for Hematological Malignancies/2010-08
  • A critical role of DNAM-1 in the development of acute graft-versus-host diseas
    Nabekura Tsukasa
    The 14th International Congress of Immunology/2010-08
  • DNAM-1は移植片対宿主病の発症において重要な役割を果たす
    鍋倉 宰; 渋谷 和子; 竹中 江里; 渋谷 彰
    第20回Kyoto T Cell Conference/2010-06-05
  • A critical role of DNAM-1 in the development of acute graft-versus-host disease
    Nabekura Tsukasa
    The Keystone Symposia on Molecular and Cellular Biology (Lymphocyte Activation)/2010-02
  • Novel prophylactic and therapeutic approaches to GVHD with a monoclonal antibody against DNAM-1
    Nabekura Tsukasa
    The 39th Annual Meeting of the Japanese Society of Immunology/2009-12
  • Novel prophylactic and therapeutic approaches to GVHD with a monoclonal antibody against DNAM-1
    Nabekura Tsukasa
    The 71st Annual Meeting of the Japanese Society of Hematology/2009-10
  • Induction of tumor-specific T cells by inoculation of genetically modified dendritic cells
    Nabekura Tsukasa
    The 18th Kyoto T Cell Conference/2008-06
  • An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2
    Nabekura Tsukasa
    The 37th Annual Meeting of the Japanese Society of Immunology/2007-11
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Intellectural property rights
  • ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
    渋谷　彰; 小田　ちぐさ; 田原　聡子; Nabekura Tsukasa; カ...
  • NKp46-CreERT2 transgenic mice
    Nabekura Tsukasa; Lanier L Lewis
  • 活性調節剤、これを含有する医薬品、および抗CD300a抗体
    渋谷 彰; 小田　ちぐさ; 田原　聡子; 鍋倉　宰; カンカーナム...
  • Use of Celiac disease-associated CD300a gene-deficient mouse, activity modulator for CD300a-expressing cells, and medical and pharmaceutical agent comprising activity modulators for CD300a-expressing cells
    渋谷 彰; 小田　ちぐさ; 鍋倉　宰
  • A Method for Generation of Antibodies Using Genetically Modified Dendritic Cells by Vectors
    小野寺 雅史; 大津 真; 鍋倉 宰
  • Adoptive Gene and Cell Therapy with Immune Cells Genetically Modified by Retroviral Vectors
    小野寺 雅史; 濱仲 早苗; 鍋倉 宰; 中内 啓光
  • ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
    渋谷　彰; 小田　ちぐさ; 田原　聡子; 鍋倉　宰; カンカーナ...
Teaching
2020 -- 2020Phase I 医学の基礎（科目番号：HB31102・秋・集中）医学の基礎コース♯5免疫学筑波大学
2020 -- (current)Medical Science Seminar III: ImmunologyUniversity of Tsukuba
2020 -- 2020免疫生物学（科目番号：EB91271・夏・集中）筑波大学
2020 -- 2020Human Infection and Immunology (01EQ131, Spring, AB） Innate ImmunityUniversity of Tsukuba
2020 -- 2020Serendipity in Human Biology（科目番号：02RA050・春・AB）筑波大学
2020 -- 2020新しい基礎医学における神経科学と免疫研究（科目番号：1D21011・春・AB）ナチュラルキラー細胞の細胞生物学筑波大学
2020 -- 2020免疫検査学実習（科目番号：HE33053・春・集中）筑波大学
2019 -- 2019Initiation Seminar (02EW037, Fall, A)University of Tsukuba
2019 -- 2019Phase I 医学の基礎（科目番号：HB31102・秋・集中）医学の基礎コース♯5免疫学筑波大学
2019 -- 2019新しい基礎医学における神経科学と免疫研究（科目番号：1D21011・春・AB）ナチュラルキラー細胞の細胞生物学筑波大学
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Other educational activities
2018 -- 2018筑波大学大学院　博士課程教育リーディングプログラム　ヒューマンバイオロジー学位プログラム　イニシャルメンター教員筑波大学
2018 -- (current)筑波大学大学院　博士課程教育リーディングプログラム　ヒューマンバイオロジー学位プログラム　担当教員資格認定筑波大学
2017 -- (current)筑波大学大学院　人間総合科学研究科博士課程　生命システム医学専攻　担当教員資格認定筑波大学
2017 -- (current)筑波大学大学院　人間総合科学研究科修士課程　フロンティア医科学専攻　担当教員資格認定筑波大学
Professional activities
2020-04 -- 2021-03Committee member of young academyThe Japanese Society for Immunology
2019-04 -- 2020-03The 8th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceChief of Management Secretariat
2018-04 -- 2019-03The 7th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceProgram committee member
2019-04 -- 2022-03The Japanese Society for ImmunologyCouncilor
2017-04 -- 2018-03The 6th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceManagement Secretariat
2017-04 -- 2018-03The Japanese Society for ImmunologyCooperation Committee Member
University Management
2018 -- (current)生存ダイナミクス研究センター　広報委員
2018 -- (current)筑波大学大学院　人間総合科学研究科博士課程　生命システム医学専攻　教務委員
Other activities
2019 -- 2024教員抜擢昇任人事制度「ツクバ・トップ・ランナー」教員
2018-07 -- 2018-07TARA公開講座　平成30年度高校生公開講座「生物の生存戦略を科学する」　“ナチュラルキラー細胞による生体防御”
2017-08 -- 2017-08Menneki Fushigi Mirai 2017 (organized by Kenji Ishiwata, the Japanese Society for Immunology) at Tokyo, Japan.
2008-05 -- 2008-05Menneki Hushigi Mirai 2008 (organized by Masayuki Miyasaka, the Japanese Society for Immunology) at Tokyo, Japan
2008-04 -- 2008-04Menneki Town Meeting Tsukuba (organized by Akira Shibuya, the Japanese Society for Immunology) at Ibaraki, Japan.

(Last updated: 2021-02-15)