Nabekura Tsukasa

Affiliation
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
Official title
Assistant Professor
Sex
Male
Birth date
1981-01
KAKEN ID
80550095
URL
Email
G'xy|$.+xE-,.$x,xE}|<KG.E-,.$.yxExzE#)
Phone
+81-29-853-3281
Research fields
Immunology
Research keywords
Natural killer cells
Immunological memory
Viral infection
Innate lymphoid cells
Immunology
Tumor immunology
Bone marrow transplant
Hematology
Research projects
記憶NK細胞の人為的分化誘導法 の開発とその応用2022-04 -- 2024-03鍋倉宰科学技術振興機構(JST)/創発的研究支援事業26,000,000Yen
記憶ナチュラルキラー細胞分化の制御機構の解明とその応用2021-04 -- 2022-03鍋倉宰国立大学法人筑波大学/研究力強化のための令和3年度特別支援シーディングプログラム10,000,000Yen
JSI 2020 Outstanding Young Immunology Researcher Award2021-01 -- 2021-12鍋倉宰特定非営利活動法人日本免疫学会/若手免疫学研究支援事業
ナチュラルキラー細胞の適応免疫特性獲得の制御機構の研究2020-04 -- 2021-03鍋倉宰国立大学法人筑波大学/令和2年度第1回 筑波大学研究基盤支援プログラム(Bタイプ)2,700,000Yen
急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割2018-04 -- 2021-03鍋倉宰The Naito Foundation/The Naito Grant for Fostering Scientific Full Bloom for the Next Generation6,000,000Yen
急性肝障害におけるDNAM-1の役割2018-04 -- 2020-03鍋倉宰Kato Memorial Bioscience Foundation/Grant-in-Aid2,000,000Yen
急性肝障害におけるDNAM-1の役割2018-04 -- 2019-03鍋倉宰Life Science Foundation of Japan/Grant-in-Aid1,000,000Yen
急性肝障害におけるDNAM-1 の役割2018-04 -- 2019-03鍋倉宰The Uehara Memorial Foundation/Grant-in-Aid2,000,000Yen
急性肝障害におけるグループ1自然リンパ球が発現するDNAM-1の役割2018-04 -- 2019-03鍋倉宰Kanae Foundation for the Promotion of Medical Science/The 46th Kanae grant1,000,000Yen
Identification of a master regulator of the differentiation of memory natural killer cells2017-04 -- 2020-03鍋倉宰Japan Society for the Promotion of Science/Grant-in-Aid for Young Scientists(A)24,310,000Yen
more...
Career history
2018-04 -- (current)University of TsukubaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)Assistant Professor
2014-03 -- 2018-03University of TsukubaLife Science Center of Tsukuba Advanced Research Alliance (TARA)International Tenure-track Assistant Professor
2014-11 -- 2016-10University of California, San FranciscoDepartment of Microbiology and Immunology, Lewis L. Lanier labAssistant Specialist
2011-11 -- 2014-10University of California, San FranciscoDepartment of Microbiology and Immunology, Lewis L. Lanier labPostdoctoral Scholar
2008-04 -- 2011-10University of TsukubaGraduate School of Comprehensive Human SciencesPostdoctoral fellow
Academic background
2005-04 -- 2008-03University of Tsukuba Graduate School of Comprehensive Human Sciences Doctoral Program in Advanced Biomedical Applications
Degree
2008-03Ph.D.University of Tsukuba
Academic societies
2017 -- (current)Japanese Society of Immunotherapy for Hematological Disorders
2012 -- 2016The American Association of Immunologist (AAI)
2009 -- 2010THE JAPANESE SOCIETY OF HEMATOLOGY
2003 -- (current)JAPANESE SOCIETY FOR IMMUNOLOGY
Honors & Awards
2018-11Young Investigator Award in University of Tsukuba
2018-02BEST FACULTY MEMBER in University of Tsukuba
2017-12The Japanese Society of Immunology Young Investigator Award
2013-05AAI Trainee Abstract Award of IMMUNOLOGY 2013 Annual Meeting, The American Association of Immunologists
2012-11Postdoctoral Fellowship for Research Abroad of the Japan Society for the Promotion of Science (JSPS)
2011-11Postdoctoral Fellowship of the Uehara Memorial Foundation
2011-11Subsidy for Inter-Institute Researches of the Naito Foundation
2011-11Fellowship for Research Abroad of the Mochida Memorial Foundation for Medical and Pharmaceutical Research
2011-01Most Valuable Presenter in the 5th Tsukuba Medical Science Research Meeting
2011-01Best Paper Award in the 5th Tsukuba Medical Science Research Meeting
2008-04Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), PD
2008-03Graduate with Summa Cum Laude (3-year graduation in 4-year Doctoral Course), University of Tsukuba
2007-04Research Fellowship for Young Scientists of the Japan Society for the Promotion of Science (JSPS), DC2
2006-01Cancer Research Fellowship for Graduate Students of Yasuda Medical Foundation
2005-03Best Paper Award in the Master’s Program in Medical Sciences, University of Tsukuba
2005-03Graduate with Summa Cum Laude (Best Paper Award in Master Course), University of Tsukuba
2003-03Graduate with Summa Cum Laude (Undergraduate Course), University of Tsukuba
Articles
Books
  • An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2
    Nabekura Tsukasa
    2008-03
Conference, etc.
  • DNAM-1 immunoreceptor protects mice from concanavalin A-induced acute liver injury by reducing neutrophil infiltration
    S Matsuo; T Nabekura; K Matsuda; Shibuya Kazuko; A. ...
    第52回日本免疫学会学術集会/2024-1-17--2024-1-19
  • Themis2 impairs anti-tumor activity of NK cells by suppressing activating NK receptor signaling
    D Elfira A.; T Nabekura; Shibuya Kazuko; A Shibuya
    第52回日本免疫学会学術集会/2024-1-17--2024-1-19
  • Identification of a functional ligand for Clec10a involved in TLR4-Mediated Skin Inflammation
    重松克伸; 鍋倉宰; 田原聡子; 金丸和正; 浩章 舘野; Shibuya Kazuko; 澁谷彰
    The 13th JSH International Symposium 2023/2023-7-21
  • 記憶NK細胞の分化制御因子Themis2の同定
    鍋倉 宰
    University of Tsukuba 50th anniversary TARA symposium/2023-06
  • Regulation of natural killer memory
    鍋倉 宰
    The 6th Japanese Society of Immunology Young Academy Seminar/2023-01
  • The scaffold protein Themis2 limits natural killer memory formation during mouse cytomegalovirus infection
    Nabekura Tsukasa
    International Symposium on Immune Regulation/2023-01
  • Future direction (young investigators’ forum: Future of Immunology)
    鍋倉 宰
    The 51st Annual Meeting of Japanese Society of Immunology/2022-12
  • 記憶NK細胞の人為的分化誘導法の開発とその応用
    鍋倉 宰
    科学技術振興機構 創発的研究支援事業 第1回「融合の場」/2022-06
  • 記憶NK細胞の人為的分化誘導法の開発とその応用
    鍋倉 宰
    科学技術振興機構 創発的研究支援事業 第2回「創発の場」/2022-03
  • Adaptive immune features of natural killer cells (afternoon seminar)
    鍋倉 宰
    The 50th Annual Meeting of the Japanese Society of Immunology/2021-12
  • Protective role of type 1 innate lymphoid cells in acute liver injury (symposium)
    Nabekura Tsukasa
    The 50th Annual Meeting of the Japanese Society of Immunology/2021-12
  • Recent advances in innate lymphocyte research (overview talk)
    Nabekura Tsukasa
    The 50th Annual Meeting of the Japanese Society of Immunology/2021-12
  • 1型自然リンパ球は急性肝障害において保護的な役割を持つ
    鍋倉 宰
    第8回筑波大学・東京理科大学合同リトリート/2020-11-14
  • Protective role of type 1 innate lymphoid cells in acute liver injury
    鍋倉 宰
    第29回東京免疫フォーラム/2021-03
  • Protective role of type 1 innate lymphoid cells in acute liver injury
    Nabekura Tsukasa
    The 48th Annual Meeting of the Japanese Society of Immunology/2019-12
  • Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus Infection
    Nabekura Tsukasa
    The 3rd International Conference of Innate Lymphoid Cel/2018-11
  • Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
    Nabekura Tsukasa
    RIKEN Center for Integrative Medical Sciences (IMS) – Japanese Society of Immunology (JSI) International Symposium on Immunology 2018/2018-06
  • 活性化受容体NKG2D はマウスサイトメガロウイルス感染時のナチュラルキラー細胞の増殖を促進するが、NKG2D シグナル単独では増殖に不十分である
    鍋倉 宰
    第6回筑波大学・東京理科大学合同リトリート/2018-03-17
  • Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
    Nabekura Tsukasa
    The 46th Annual Meeting of the Japanese Society of Immunology/2017-12
  • 共刺激分子DNAM-1はサイトメガロウイルス感染時に於ける記憶ナチュラルキラー分化に必要である
    鍋倉 宰; 金谷 穣; 渋谷 彰; Guo Fu; Gascoigne Nicholas R.J; Lanier Le...
    第9回血液疾患・免疫療法学会学術集会/2017-09-30
  • 自己MHCクラスIを認識する活性化NK細胞受容体はNK細胞のエフェクター機能と記憶細胞分化を促進する
    鍋倉 宰
    第9回血液・疾患免疫療法学会学術集会/2017-09-30
  • Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    第26回東京免疫フォーラム/2017-03
  • Natural killer cell licensing and tolerance modulate differentiation of natural killer cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    The 44th Annual Meeting of the Japanese Society of Immunology/2015-11
  • DNAM-1 is required for expansion of effector NK cells and generation of memory NK cells during mouse cytomegalovirus infection
    Nabekura Tsukasa
    IMMUNOLOGY 2013 AAI Annual Meeting at Honolulu/2013-05
  • 活性化免疫受容体DNAM-1の急性肝GVHDの病態形成における重要な役割
    金谷 穣; 渋谷 和子; 阿部 史枝; 鍋倉 宰; 渋谷 彰
    第4回造血器腫瘍免疫療法研究会学術集会/2012-08-18
  • more...
Intellectural property rights
  • ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
    渋谷 彰; 小田 ちぐさ; 田原 聡子; Nabekura Tsukasa; カンカーナム ガマゲ サナトゥ ウダヤンガ...
  • NKp46-CreERT2 transgenic mice
    Nabekura Tsukasa; Lanier L Lewis
  • 活性調節剤、これを含有する医薬品、および抗CD300a抗体
    渋谷 彰; 小田 ちぐさ; 田原 聡子; 鍋倉 宰; カンカーナム ガマゲ サナトゥ ウダヤンガ; 三木 春香; 飯野 秀一
  • Use of Celiac disease-associated CD300a gene-deficient mouse, activity modulator for CD300a-expressing cells, and medical and pharmaceutical agent comprising activity modulators for CD300a-expressing cells
    渋谷 彰; 小田 ちぐさ; 鍋倉 宰
  • A Method for Generation of Antibodies Using Genetically Modified Dendritic Cells by Vectors
    小野寺 雅史; 大津 真; 鍋倉 宰
  • Adoptive Gene and Cell Therapy with Immune Cells Genetically Modified by Retroviral Vectors
    小野寺 雅史; 濱仲 早苗; 鍋倉 宰; 中内 啓光
  • ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
    渋谷 彰; 小田 ちぐさ; 田原 聡子; 鍋倉 宰; カンカーナム ガマゲ サナトゥ ウダヤンガ; 三木 春香; 飯野 秀一
Teaching
2024 -- 2024医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年)筑波大学
2023 -- 2023Human Infection and ImmunologyUniversity of Tsukuba.
2023 -- 2023ImmunobiologyUniversity of Tsukuba.
2023 -- 2023Practice of ImmunologyUniversity of Tsukuba.
2023 -- 2023医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年)筑波大学
2022 -- 2022Early Career Immunology Digital Seminar Series 2022University of California, Los Angeles
2022 -- 2022免疫生物学(科目番号:EB91271・夏・集中)筑波大学
2022 -- 2022ヒトの感染と免疫(Human Infection and Immunology)(科目番号:01EQ131・春・AB)筑波大学
2022 -- 2022免疫検査学実習(科目番号:HE33053・春・集中)筑波大学
2021 -- 2021医科学セミナーIII(免疫学)(0AS0503/01EQ040・通年)筑波大学
more...
Other educational activities
2019 -- 2023教員抜擢昇任人事制度「ツクバ・トップ・ランナー」教員
2018 -- 2018筑波大学大学院 博士課程教育リーディングプログラム ヒューマンバイオロジー学位プログラム イニシャルメンター教員筑波大学
2018 -- (current)筑波大学大学院 博士課程教育リーディングプログラム ヒューマンバイオロジー学位プログラム 担当教員資格認定筑波大学
2017 -- (current)筑波大学大学院 人間総合科学研究科博士課程 生命システム医学専攻 担当教員資格認定筑波大学
2017 -- (current)筑波大学大学院 人間総合科学研究科修士課程 フロンティア医科学専攻 担当教員資格認定筑波大学
Professional activities
2023-04 -- 2024-03The 10th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceProgram committee member
2022-04 -- 2023-03The 9th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceManagement Secretariat
2020-04 -- (current)The Japanese Society for ImmunologyCommittee member of young academy
2019-04 -- 2020-03The 8th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceChief of Management Secretariat
2018-04 -- 2019-03The 7th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceProgram committee member
2019-04 -- (current)The Japanese Society for ImmunologyCouncilor
2017-04 -- 2018-03The 6th Retreat of Univ. of Tsukuba and Tokyo Univ. of ScienceManagement Secretariat
2017-04 -- 2018-03The Japanese Society for ImmunologyCooperation Committee Member
University Management
2020 -- (current)生存ダイナミクス研究センター 内部交流会TARA Biweekly Mixerオーガナイザー
2018 -- (current)生存ダイナミクス研究センター 広報委員
Other activities
2022-07 -- 2022-07TARA公開講座 令和4年度公開講座「感染と恒常性の生命科学」 “ナチュラルキラー細胞による生体防御”
2022-07 -- 2022-07筑波大学 高大連携事業 免疫学「感染症」
2018-07 -- 2018-07TARA公開講座 平成30年度高校生公開講座「生物の生存戦略を科学する」 “ナチュラルキラー細胞による生体防御”
2017-08 -- 2017-08Menneki Fushigi Mirai 2017 (organized by Kenji Ishiwata, the Japanese Society for Immunology) at Tokyo, Japan.
2008-05 -- 2008-05Menneki Hushigi Mirai 2008 (organized by Masayuki Miyasaka, the Japanese Society for Immunology) at Tokyo, Japan
2008-04 -- 2008-04Menneki Town Meeting Tsukuba (organized by Akira Shibuya, the Japanese Society for Immunology) at Ibaraki, Japan.

(Last updated: 2024-03-27)