TAKAHASHI Aki
- Affiliation
- Institute of Human Sciences
- Official title
- Associate Professor
- URL
- Office
- Laboratory of Behavioral Neurobiology
- Research fields
Neurophysiology / General neuroscience Basic / Social brain science Animal physiology/Animal behavior Experimental psychology - Research keywords
Dorsal raphe nucleus Neural circuit Aggressive behavior - Research projects
攻撃行動の昂進とミクログリアの関係の解明 2023-04 -- 2025-03 高橋阿貴 公益財団法人アステラス病態代謝研究会2023年度研究助成/ 運動が攻撃性を抑制する神経・分子メカニズムの解明 2022 -- 2024 高橋 阿貴 Japan Society for the Promotion of Science/Grant-in-Aid for Challenging Research (Exploratory) 6,240,000Yen 社会的孤立による攻撃性の昂進にかかわる腸脳相関の解明 2022-04 -- 2026-03 高橋阿貴 日本学術振興会/基盤研究(B) 怒りの爆発を抑える生物学的基盤の解明 2022-04 -- 2025-03 Aki Takahashi 科学技術振興機構(JST)/FOREST 攻撃性と脳内免疫細胞の関係の構成的理解 2021-04 -- 2023-03 高橋阿貴 JSPS/新学術領域研究(公募研究) ストレスに起因する過剰な攻撃性を低下させる機能性食品の開発 2020-11 -- 2022-03 Aki Takahashi 科学技術振興機構(JST)/A-STEPトライアウト 過剰な攻撃性にかかわる神経回路の構成的理解 2019-04 -- 2021-03 高橋阿貴 Japan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area) 動物のヒトへのなつき行動における遺伝子・神経回路および行動学的基盤の解明 2019-04 -- 2022-03 Tsuyoshi Koide Japan Society of for the Promotion of Science/日本学術振興会/科研費 基盤研究(B) 過剰な攻撃行動と免疫系をつなぐ神経メカニズムの解析 2017-04 -- 2021-03 Aki Takahashi JSPS/科学研究費 若手研究(A) 苛立ちの神経回路 2015-04 -- 2018-03 Aki Takahashi JSPS/KAKENHI more... - Career history
2019-01 -- (current) 筑波大学人間系准教授 2014-09 -- 2018-12 University of Tsukuba人間系助教 2015-05 -- 2017-11 Icahn School of Medicine at Mount SinaiCenter for Affective NeuroscienceVisiting Assistant Professor 2015-05 -- 2017-03 The Rockefeller UniversityLaboratory of NeuroendocrinologyVisiting Assistant Professor 2010-04 -- 2014-08 National Institute of GeneticsMouse Genomics Resource LaboratoryResearch associate 2007-11 -- 2010-03 Tufts UniversityDepartment of PsychologyPostdoctoral fellow 2007-04 -- 2007-10 National Institute of GeneticsMouse Genomics Resource LaboratoryPostdoctoral fellow - Academic background
2004-04 -- 2007-03 The Graduate University for Advanced Studies (SOKENDAI) School of Life Science Department of Genetics 2002-04 -- 2004-03 University of Tsukuba Graduate School of Comprehensive Human Science Kansei, Behavioral and Brain Science 1997 -- 2002 University of Tsukuba Second Cluster of Collegee College of Human Sciences - Degree
2007-03 Doctor of Philosophy (Biology) The Graduate University for Advanced Studies 2004-03 修士(行動科学) University of Tsukuba - Academic societies
2002 -- (current) THE JAPANESE SOCIETY FOR ANIMAL PSYCHOLOGY 2006 -- (current) THE JAPAN NEUROSCIENCE SOCIETY 2017 -- (current) 日本生理学会 2016 -- (current) International Society for Research on Aggression 2010 -- (current) Society for Neuroscience - Honors & Awards
2022-03-17 第12回入澤彩記念女性生理学者奨励賞 2018-12 筑波大学若手教員奨励賞 2005 上武学術奨励賞 2007-10 Nature Genetics Award ポスター発表 2013-07 JSBN一般の部 優秀発表賞 2014-07 森脇和郎賞 - Articles
- Associations of the immune system in aggression traits and the role of microglia as mediators
Takahashi Aki
NEUROPHARMACOLOGY/256, 2024-09-15 - 攻撃行動の神経学的基盤
高橋 阿貴
臨床精神医学/52(6)/pp.599-605, 2023-06 - Aggression modulator: Understanding the multifaceted role of the dorsal raphe nucleus.
Mitsui Koshiro; Takahashi Aki
BioEssays/46(4), 2024-04 - The role of social isolation stress in escalated aggression in rodent models
Takahashi Aki
Neuroscience research/p.S0168-0102(22)00212-7, 2022-07-30 - Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
Takahashi Aki; Durand-de Cuttoli Romain; Flanigan Megh...
Nature communications/13(1)/p.4039, 2022-07-21 - Neuromodulatory effect of interleukin 1b in the dorsal raphe nucleus on individual differences in aggression
Takahashi Aki; Aleyasin Hossein; Stavarache Mihaela A.; L...
Molecular Psychiatry/27(5)/pp.2563-2579, 2022-05 - 社会的敗北の動物モデル
高橋 阿貴
精神科/39(1)/pp.17-23, 2021-07 - 過剰な攻撃行動の脳内メカニズム
高橋 阿貴
Medical Science Digest/46/pp.50-51, 2020-05 - Toward Understanding the Sex Differences in the Biological Mechanism of Social Stress in Mouse Models
Takahashi Aki
Frontiers in psychiatry/12, 2021-02 - Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice
Flanigan Meghan E.; Aleyasin Hossein; Li Long; Burnett C...
NATURE NEUROSCIENCE/23(5)/pp.638-650, 2020-04 - Neuroendocrinological basis of maternal behavior: A review on the role of the medial preoptic area of the hypothalamus
村川 友哲; 高橋 阿貴; 小川 園子
筑波大学心理学研究/56/pp.1-12, 2018-08 - Cell-type-specific role of ΔFosB in nucleus accumbens in modulating inter-male aggression
Aleyasin Hossein; Flanigan Meghan E; Golden Sam A; Tak...
The Journal of Neuroscience/38(26)/pp.5913-5924, 2018-06 - Aggression, Social Stress, and the Immune System in Humans and Animal Models
Takahashi Aki; Flanigan Meghan E.; McEwen Bruce S.; Russo...
Frontiers in Behavioral Neuroscience/12, 2018-03 - Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility
Heshmati Mitra; Aleyasin Hossein; Menard Caroline; Christ...
Proceedings of the National Academy of Sciences of the United States of America/115(5)/pp.1111-1116, 2018-01 - 過剰な攻撃行動の神経生物学―動物行動神経科学の視点から
Takahashi Aki
臨床精神医学/46(9)/pp.1077-1082, 2017-09 - Social stress induces neurovascular pathology promoting depression
Menard Caroline; Pfau Madeline L; Hodes Georgia E; Kana ...
Nature Neuroscience/20(12)/pp.1752-1760, 2017-12 - Establishment of a repeated social defeat stress model in female mice
Takahashi Aki; Chung Jia-Ru; Zhang Song; Zhang Hongxing; ...
Scientific Reports/7(1), 2017-10 - Combinatorial Psycho-Pharmacological Approaches for the Treatment of Abnormal Aggression
Golden Sam A; Takahashi Aki
Neuropsychopharmacology/43(2)/pp.233-234, 2018-01 - Pup exposure facilitates retrieving behavior via the oxytocin neural system in female mice
Okabe Shota; Tsuneoka Yousuke; Takahashi Aki; Ooyama Rum...
Psychoneuroendocrinology/79/pp.20-30, 2017-05 - An emerging role for the lateral habenula in aggressive behavior
Flanigan Meghan; Aleyasin Hossein; Takahashi Aki; Golden ...
Pharmacology, biochemistry, and behavior/162(SI)/pp.79-86, 2017-05 - Persistent conditioned place preference to aggression experience in adult male sexually-experienced CD-1 mice
Golden SA; Aleyasin H; Heins R; Flanigan M; Heshmati M; Takaha...
Genes Brain and Behavior/16(1)/pp.44-55, 2016-07 - Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task
Hirata Haruna; Takahashi Aki; Shimoda Yasushi; Koide Tsuyoshi
PLOS ONE/11(1), 2016-01 - alpha 2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice
Newman Emily L.; Smith Kiersten S.; Takahashi Aki; Chu Adam; ...
Psychopharmacology (Berl)/232(23)/pp.4359-4369, 2015-12 - Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress
Hodes Georgia E.; Pfau Madeline L.; Purushothaman Immanuel; ...
The Journal of Neuroscience/35(50)/pp.16362-16376, 2015-12 - Mapping of Genetic Factors That Elicit Intermale Aggressive Behavior on Mouse Chromosome 15: Intruder Effects and the Complex Genetic Basis
Takahashi Aki; Sugimoto Hiroki; Kato Shogo; Shiroishi Toshih...
PLOS ONE/10(9), 2015-09 - more...
- Associations of the immune system in aggression traits and the role of microglia as mediators
- Books
- Link Between the Immune System and Aggression
Takahashi Aki; Russo SJ
Handbook of Anger, Aggression, and Violence/Springer/pp.2803-2826, 2023-08 - Link Between the Immune System and Aggression
Takahashi Aki; SJ Russo
Handbook of Anger, Aggression, and Violence/Springer, 2023-01 - Social Stress and Aggression in Murine Models
Takahashi Aki
Neuroscience of Social Stress/Springer Cham/p.181, 2022-05 - Serotonin and aggression-an update
Quadros Isabel M.; Takahashi Aki; Miczek Klaus A.
HANDBOOK OF THE BEHAVIORAL NEUROBIOLOGY OF SEROTONIN, 2ND EDITION/ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD/pp.635-663, 2020 - Serotonin in aggressive and violent behavior.
Quadros IM; Takahashi Aki; Mickzek KA
Handbook of the Behavioral Neurobiology of Serotonin 18/Elsevier, 2009 - 系統について知ろう(第2章)、マウスの行動を解析しよう(第10章)
Takahashi Aki; 小出剛
マウス実験の基礎知識/オーム社, 2008 - Neurogenetics of aggressive behavior: Studies in rodents
Takahashi A; Miczek KA
Current Topics in Behavioral Neurosciences. 17/Springer, 2014 - Behavioral and pharmacogenetics of aggressive behavior
Takahashi A; Quadros IM; de Almeida RM; Miczek KA
Current Topics in Behavoral Neurosciences. 12/Springer/pp.73-138, 2012 - 系統について知ろう(第2章)、マウスの行動を解析しよう(第10章)
高橋 阿貴; 小出剛
マウス実験の基礎知識 第2版, 2013 - Pathological aggression
Sluyter F; Takahashi A; Maxson SC
Behavioral Genetics of the Mouse Vol. 2: Genetic Mouse Model of Neurobehavioral Disorders/Cambridge University Press/pp.86-96, 2014
- Link Between the Immune System and Aggression
- Conference, etc.
- 攻撃的覚醒状態に関わる神経回路の解析
高橋 阿貴
情動研究会2023「情動の本質を捉える最先端研究アプローチ」/2023-09-25--2023-09-26 - Optogenetic activation of the lateral hypothalamus-dorsal raphe nucleus projection: influences on male mice aggression.
Mitsui Koshiro; Takahashi Aki
Society for Social Neuroscience (S4SN)/2024-03-25--2024-03-28 - Factors that are involved in aggression priming in male mice.
Nagai Tomoya; Hu Brian; Takahashi Aki
Society for Social Neuroscience (S4SN)/2024-03-25--2024-03-28 - Instigator’s familiarity, but not dominant-subordinate relationships, affects social instigation-heightened aggression.
Tomoya Nagai; Takahashi Aki
遺伝研研究会「社会性の個体差を生み出す生物学的基盤」/2023-12-26--2023-12-27 - Exploring the role of the lateral hypothalamus-dorsal raphe nucleus pathway in regulating inter-male aggression in mice
Mitsui Koshiro; Takahashi Aki
遺伝研研究会「社会性の個体差を生み出す生物学的基盤」/2023-12-26--2023-12-27 - The effect of dominant-subordinate relationships on olfactory instigation-heightened aggression in male mice.
Nagai Tomoya; Takahashi Aki
日本動物心理学会第83回大会/2023-10-08--2023-10-09 - Modulation of aggressive behavior in male mice through lateral hypothalamic neurons projecting to the dorsal raphe nucleus.
Mitsui Koshiro; Takahashi Aki
日本動物心理学会第83回大会/2023-10-08--2023-10-09 - 処女雌マウスの雌間攻撃行動モデルの確立の試み
永井智也; 高橋 阿貴
第37回JSBN学術集会/2023-08-31--2023-09-02 - Characterization of the lateral hypothalamic input into the dorsal raphe nucleus on aggressive behavior in male mice.
Mitsui Koshiro; Takahashi Aki
第46回日本神経科学大会/2023-08-01--2023-08-04 - 心理社会的ストレスモデルマウスにおける肝臓代謝物の網羅解析
谷島優平; 中村勇; 川瀬貴博; 塚原隆充; 高橋 阿貴; 豊田淳
日本畜産学会第131回大会/2023-09-18--2023-09-21 - Peripheral-Central Interactions in Individual Differences in Aggression.
Takahashi Aki
Research Unit “Peripheral-Central Interaction in Stress” Kickoff Symposium/2024-03-14 - Role of central immune cells in individual differences in aggression in male mice.
高橋 阿貴
第66回日本神経化学学会/2023-07-06--2023-07-08 - Aggressive arousal: an internal state that escalates aggressive behavior.
Takahashi Aki
第46回日本神経科学大会/2023-08-01--2023-08-04 - Role of the dorsal raphe nucleus on socially enhanced aggression in male mice.
Takahashi Aki
第97回日本薬理学会年会/2023-12-14--2023-12-16 - Mechanisms of experience-induced shift of aggression state in the mouse.
Takahashi Aki
第101回日本生理学会大会/2024-03-28--2024-03-30 - Neural circuit for of aggressive arousal induced by provocation in male mouse
Takahashi Aki
EBPS2022 Biennial Workshop/2022-6-24--2022-6-26 - マウスモデルから明らかにする攻撃性の脳内メカニズム
Takahashi Aki
犯罪心理学会第60回大会/2022-9-3--2022-9-4 - 攻撃性の神経生物学的基盤のマルチスケール解析
Takahashi Aki
次世代脳プロジェクト冬のシンポジウム2022/2022-12-14--2022-12-17 - Neurobiology of stress and aggressive behavior.
Takahashi Aki
日本生理学会第100回記念大会/2023-03-14 - Optogenetic stimulation of the dorsal raphe nucleus-projecting lateral hypothalamic neurons increases inter-male aggression in mice
Mitsui Koshiro; Ogawa Sonoko; Takahashi Aki
Tsukuba Global Science Week (TGSW) 2021/2021-09-06--2021-09-11 - Differential distribution and neuronal projection of estrogen receptor α and β expressing cells in the lateral septum
Hasunuma Kansuke; Sano Kazuhiro; Takahashi Aki; Ogawa So...
Tsukuba Global Science Week (TGSW) 2021/2021-09-06--2021-09-11 - マウスにおける腸内細菌叢と攻撃行動の関係の探索
岡本昂大; 三井鴻志郎; 小川園子; 高橋 阿貴
JSBN2021/2021-09-18--2021-09-19 - The Role of 5-HT Neurons in the DRN on Social Instigation-Heightened Aggression in Male Mice
Noda Tomomi; Mitsui Koshiro; Tanaka Kenji F; Yamanaka Ak...
日本動物心理学会第82回大会/2022-10-15--2022-10-16 - The effect of pharmacological elimination of microglia in intermale aggression of mouse
Shimoji Rion; 高橋 阿貴
日本動物心理学会第82回大会/2022-10-15--2022-10-16 - 外側視床下部から背側縫線核に投射する神経細胞が、雄マウスの種内攻撃行動および捕食攻撃行動に及ぼす影響
三井鴻志郎; 高橋 阿貴
日本行動神経内分泌研究会(JSBN)2022/2022-06-30--2022-07-03 - more...
- 攻撃的覚醒状態に関わる神経回路の解析
- Teaching
2024-10 -- 2025-02 Special Lecture in Kansei , Behav ioral and Brain Sciences 4 University of Tsukuba. 2024-04 -- 2024-08 Special Lecture in Kansei , Behav ioral and Brain Sciences 4 University of Tsukuba. 2024-07 -- 2024-09 Neuroscience Laboratories C University of Tsukuba. 2024-10 -- 2025-02 Special Lecture in Kansei , Behavioral and Brain Sciences 6 University of Tsukuba. 2024-04 -- 2024-08 Special Lecture in Kansei , Behavioral and Brain Sciences 6 University of Tsukuba. 2024-10 -- 2024-12 Psychological Research Methods University of Tsukuba. 2024-04 -- 2024-08 Special Lecture in Kansei , Behav ioral and Brain Sciences 5 University of Tsukuba. 2024-10 -- 2025-02 Special Lecture in Kansei , Behav ioral and Brain Sciences 5 University of Tsukuba. 2024-10 -- 2025-02 Laboratory for Behavioral Neuroscience University of Tsukuba. 2024-04 -- 2024-08 Laboratory for Behavioral Neuroscience University of Tsukuba. more... - Talks
- Neural circuit for aggressive arousal induced by provocation in male mouse
高橋 阿貴
FRIS/TI-FRIS Life Science Seminar/2023-01-26 - 怒り」やストレスにかかわる神経生物学的基盤の探索
高橋 阿貴
富山大学 生命融合科学教育部セミナー/2022-12-23 - 「怒り」をエンコードする神経回路の探索
高橋 阿貴
第20回若手・中堅脳科学研究者のオンライン勉強会/2022-10-25 - Neural circuits that promote aggressive arousal in male mice
Takahashi Aki
RIKEN CBS forum/2022-08-12 - 攻撃行動が過剰になる神経メカニズムの探索
高橋 阿貴
脳科学セミナー「攻撃行動の薬理学・神経科学」/2019-8-20--2019-8-20 - 過剰な攻撃行動に関わる神経生物学的基盤
高橋 阿貴
第248回つくばブレインサイエンス・セミナー/2019-4-23--2019-4-23 - Neurobiology of escalated aggressive behavior
Takahashi Aki
RIKEN CBS forum/2019-6-21--2019-6-21 - Neuromodulatory role of cytokine on individual difference of aggression.
Takahashi Aki
The Third Sino-Japan Symposium on The Frontier of Behavioral Neuroendocrinology./2019-03-20--2019-03-22 - 攻撃行動の個体差を生み出す神経回路と免疫系の相互作用
高橋 阿貴
2018年度遺伝研研究会「遺伝要因と環境要因の相互作用による行動決定のメカニズム」/2018-09-28--2018-09-29 - 適応的な攻撃行動の破綻に関わる神経回路としての背側縫線核の役割
高橋 阿貴
2018年度情動研究会「情動の神経回路機構とその破綻」/2018-9-18--2018-9-19 - Individual difference of aggression and immune system.
Takahashi Aki
1974th Biological Symposium/2017-12-20--2017-12-20 - Neurobiological mechanisms of escalated aggression in mice: GABA receptor modulation of dorsal raphé nucleus.
Takahashi Aki
大阪大学神経回路機能学セミナー/2011-05-02 - 過剰な攻撃行動に関わる神経生物学的基盤:マウスの背側縫線核のGABA受容体による制御
Takahashi Aki
独協医科大学セミナー/2012-07-23 - The role of dorsal raphe nucleus and medial prefrontal cortex on escalated aggression
Takahashi Aki
第1回幸福脳研究会/2013-10-18 - 過剰な攻撃行動に関わる神経メカニズム
Takahashi Aki
第5回農医連携セミナー/2014-06-13 - 行動の多様性に関わる遺伝的基盤の探索:MSMの性格を生み出す遺伝学
Takahashi Aki
第28回モロシヌス研究会(森脇和郎賞受賞講演)/2014-06-27 - 動物の“怒り”のこころの神経科学
Takahashi Aki
JAB & RCAS 合同公開シンポジウム『動物のこころを科学する』/2015-01-30 - けんかと暴力の脳科学
Takahashi Aki
「脳科学の達人 2017」プレゼンプレビューイベント/2017-05-28 - 攻撃行動の脳科学
Takahashi Aki
第40回日本神経科学大会市民公開講座「脳科学の達人2017」/2017-07-23 - 過剰な攻撃行動を制御する神経メカニズム:背側縫線核と内側前頭前野
Takahashi Aki
第16回神経科学領域における分子モニタリングシンポジウム/2013-12-20 - 過剰な攻撃行動の脳内メカニズム:マウスの背側縫線核の役割
Takahashi Aki
シンポジウム“攻撃性の脳内基盤:基礎と臨床"/2017-04-08 - Neurobiology of escalated aggression in male mice
Takahashi Aki
AAAS 2016, Workshop on "Integrating Neuroscience and Mathematics to Elucidate Mental Activities"/2016-02-13
- Neural circuit for aggressive arousal induced by provocation in male mouse
- Professional activities
2023-04 -- (current) 日本神経科学学会 ニュース編集委員 2020-11 -- (current) THE JAPANESE SOCIETY FOR ANIMAL PSYCHOLOGY 理事 2011-09 -- 2014-07 THE JAPANESE SOCIETY FOR ANIMAL PSYCHOLOGY 会計幹事 2014-11 -- 2022-03 日本行動神経内分泌研究会 総務 2021-01 -- (current) 日本動物心理学会 動物心理学研究編集委員 2017-12 -- 2020-11 日本動物心理学会 渉外幹事 2017-02 -- 2020-04 The Japan Neuroscience Society ニュース編集委員会
(Last updated: 2024-09-18)