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Yamada Tomoko

Faculty of Medicine
Official title
Assistant Professor
Research fields
Molecular biology
Research keywords
molecular biology, neuroscience
Research projects
神経におけるGatad2bの機能の解明2017-04 -- 2018-03山田朋子ブレインサイエンス財団/研究助成金800,000Yen
神経分化や行動による遺伝子発現とヒストンH2A.zによるエピジェネッティック制御2017-04 -- 2020-03山田朋子Japan Society of for the Promotion of Science/科学研究費補助金若手研究(A)18,720,000Yen
  • RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
    Valnegri Pamela; Huang Ju; Yamada Tomoko; Yang Yue; Mejia...
    Nature communications/8(1)/p.1271, 2017-11
  • Chromatin remodeling inactivates activity genes and regulates neural coding
    Yang Yue; Yamada Tomoko; Hill Kelly K.; Hemberg Martin; R...
    SCIENCE/353(6296)/pp.300-305, 2016-07
  • Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain
    Yamada Tomoko; Yang Y; Hemberg M; Yoshida T; Cho HY; J. M...
    Neuron, 2014-07
  • TheX-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain
    Zhang C; Mejia LA; Huang J; Valnegri P; Bennett EJ; Ancka...
    Neuron, 2013-06
  • MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons
    Yamada Tomoko; Yang Y; Huang J; Coppola G; Geschwind DH; ...
    The Journal of Neuroscience, 2013-03
  • Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity
    Yamada Tomoko; Yang Y; Bonni A
    Trends in Neurosciences, 2013-01
  • A FOXO-Pak1 transcriptional pathway controls neuronal polarity
    de la Torre-Ubieta L; Gaudillière B; Yang Y; Ikeuchi Y; Y...
    Genes & Dev., 2010-04
  • DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation
    Chen Y; Yamaguchi Y; Tsugeno Y; Yamamoto J; Yamada Tomoko...
    Genes & Dev., 2009-12
  • A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation
    Yang Y; Kim AH; Yamada Tomoko; Wu B; Bilimoria PM; Ikeuch...
    Science, 2009-10
  • A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9
    Mohideen F; Capili AD; Bilimoria PM; Yamada Tomoko; Bonni...
    Nat. Struct. Mol. Biol., 2009-08
  • Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis
    Komori T; Inukai N; Yamada Tomoko; Yamaguchi Y; Handa H.
    Genes Cells, 2009-03
  • Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons
    Yuan Z; Becker EB; Merlo P; Yamada Tomoko; DiBacco S; Kon...
    Science, 2008-03
  • P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation
    Yamada Tomoko; Yamaguchi Y.; Inukai N.; Okamoto S.; Mura ...
    Mol. Cell, 2006-01
  • Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro
    Endoh M.; Zhu W.; Hasegawa J.; Watanabe H.; Kim D. K.; Ai...
    Mol. Cell. Biol., 2004-04
  • A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis
    Inukai N.; Yamaguchi Y.; Kuraoka I.; Yamada Tomoko; Kamij...
    J Biol. Chem., 2004-02
  • Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex.
    Kim D. K.; Inukai N.; Yamada Tomoko; Furuya A.; Sato H.; ...
    Genes Cells., 2003-04
  • Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex.
    Narita T; Yamaguchi Y.; Yano K.; Sugimoto S.; Chanarat S....
    Mol.Cell.Biochem., 2003-03
  • A rapid purification method for human RNA polymerase II by two-step affinity chromatography
    Hasegawa J.; Endou M.; Narita T.; Yamada Tomoko; Yamaguch...
    J Biochem., 2003-01
2018-10 -- 2019-02Seminar in Genome and Environmental Medicine IIUniversity of Tsukuba.
2018-10 -- 2019-02Lecture and Discussion in Genome and Environmental Medicine IIUniversity of Tsukuba.
2018-10 -- 2019-02Practice in Genome and Environmental Medicine IIUniversity of Tsukuba.
2018-04 -- 2018-08Seminar in Genome and Environmental Medicine IUniversity of Tsukuba.
2018-04 -- 2018-08Lecture and Discussion in Genome and Environmental Medicine IUniversity of Tsukuba.
2018-04 -- 2018-08Practice in Genome and Environmental Medicine IUniversity of Tsukuba.
2018-10 -- 2019-02Dissertation in Medical SciencesUniversity of Tsukuba.
2018-10 -- 2019-02Internship IUniversity of Tsukuba.
2018-10 -- 2019-02Internship IIUniversity of Tsukuba.
2018-10 -- 2019-02Seminar on Basic Medical SciencesUniversity of Tsukuba.

(Last updated: 2018-08-20)