KIMURA Kenichi

Affiliation
Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
Official title
Assistant Professor
ORCID
0000-0002-0363-8865
URL
Email
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Phone
029-853-7323
Research fields
Cell biology
Pathological medical chemistry
Research keywords
組織幹細胞
血管生物学
微小環境
疾患モデル
細胞外マトリクス
変形性関節症
骨疾患
大動脈解離
Research projects
内在性間葉系幹細胞を用いた変形性関節症治療のための再生医療基盤の開発2023-07 -- 2026-03木村健一AMED/「再生・細胞医療・遺伝子治療実現加速化プログラム（再生・細胞医療・遺伝子治療研究開発課題（基礎応用研究課題））」39,000,000Yen
変形関節症における軟骨変性メカニズムの解明2023-07 -- 2028-03木村健一Takeda Science Foundation/2023年度　医学系研究助成（基礎）2,000,000Yen
CD73陽性細胞による骨髄造血微小環境形成メカニズムの解明2023-04 -- 2025-03木村健一稲盛財団/稲盛研究助成1,000,000Yen
細胞外マトリクスを基軸とした胸部大動脈疾患の発生機序の解明と新規治療法の開発2023-04 -- 2027-03柳沢裕美日本学術振興会/科学研究費補助金 基盤研究（A）46,800,000Yen
細胞系譜解析を用いたCD73発現細胞による骨髄ニッチ形成および骨修復機構の解明2022-04 -- 2025-03木村健一日本学術振興会/基盤研究(C)4,290,000Yen
CD73発現細胞による骨髄微小環境の細胞ダイナミクスの解明2022-04 -- 2023-03木村健一ノバルティス科学振興財団/第35回　ノバルティス研究奨励金1,000,000Yen
ミクロフィブリル変異による大動脈解離の病態解明2021-10 -- 2025-03柳沢裕美/国際共同研究加速基金(国際共同研究強化(B))19,110,000Yen
微小発現解析による大動脈解離の新規バイオマーカーの探索2021-11 -- 2023-03木村健一かなえ医薬振興財団/2021年度研究助成金1,000,000Yen
細胞系譜解析から紐解く骨髄微小環境形成機構の解明2021-01 -- 2022-04木村健一上原記念生命科学財団/2020年度 研究奨励金2,000,000Yen
細胞系譜解析から紐解く骨髄造血微小環境の形成機構の解明2020-12 -- 2021-12木村健一テルモ生命科学振興財団/2020年度 研究助成2,000,000Yen
more...
Career history
2020-04 -- (current)筑波大学 生存ダイナミクス研究センターAssistant Professor
2012-09 -- 2020-03University of Bonn, Institute of Physiology IPostdoctoral Reseacher
2012-04 -- 2012-08筑波大学　医学医療系Postdoctoral Reseacher
Academic background
-- 2012-03筑波大学大学院人間総合科学研究科　生命システム医学専攻
Degree
2012-03博士（医学）筑波大学
Academic societies
2022 -- (current)日本結合組織学会
2021 -- (current)The Molecular Biology Society of Japan
2006 -- (current)日本再生医療学会
2011 -- (current)国際幹細胞学会
2021 -- (current)The Japanese Biochemical Society
2021 -- (current)The Japanese Vascular Biology and Medicine Organization
2021 -- (current)THE JAPANESE CIRCULATION SOCIETY
2012 -- 2020ドイツ生理学会
Honors & Awards
2022-12The Excellent Abstract Award ( 日本循環器学会基礎研究フォーラム2022)
2021-12若手奨励賞(日本血管生物医学会)
2009-11The Excellent Poster Award (The 2nd Leading Graduate Schools International Conference)
2009-09The Young Scientist Award (日本生化学会関東支部例会）
Articles
Books
  • 大動脈瘤への分子生物学的アプローチ
    木村 健一; 柳沢裕美
    心臓/日本医学出版, 2022-06
Conference, etc.
  • Role of CD73-lineage cells in articular cartilage degeneration and remodeling in osteoarthritis
    Hosomi Nao; Matsumiya Marina; Yanagisawa Hiromi; Kimur...
    Tsukuba Global Science Week 2024/2024-10-03--2024-10-04
  • Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis
    Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
    Tsukuba Global Science Week 2024/2024-10-03--2024-10-04
  • Anti-inflammatory Nanoparticles as Potential Treatment for Aortic Dissection
    Clarin M.T.R.D.C.; Motoyama Eri; A. Nabil; Kanki Sach...
    NIMS Award Symposium/2024-11-06--2024-11-07
  • Nanoparticles as a potential therapeutic tool for targeting M1 macrophages in Aortic Dissection
    Clarin M.T.R.D.C.; Motoyama Eri; A. Nabil; Kanki Sach...
    Tsukuba Global Science Week 2024/2024-10-03--2024-10-04
  • Converting one differentiated cell identity into another: Insights from Drosophila enteroendocrine cells
    Qian Qingyin; Hayashi Makoto; Nagai Hiroki; Kimura Ke...
    The 16th Japanese Drosophila Research Conference (JDRC16)/2024-09-17--2024-09-19
  • 新規Fibrillin-1点変異マウスモデルを⽤いた⼤動脈解離発症機序の解明
    木村 健一
    第10回MatriCellフォーラム/2024-9-7--2024-9-8
  • A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation
    LI Kai; Chen Lili; Fujisawa Nanami; Kimura Kenichi; M...
    The 40th annual meeting of JSDDS/2024-07-09--2024-07-11
  • CELL LINEAGE ANALYSIS OF CD73-POSITIVE CELLS IN OSTEOCHONDRAL TISSUE
    Kimura Kenichi; Ishi Ryutaro; Yanagisawa Hiromi
    The International Society for Stem Cell Research 2024/2024-07-09--2024-07-13
  • Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
    Kimura Kenichi; Motoyama Eri; Kanki Sachiko; Asano Ke...
    International Vascular Biology Meeting 2024/2024-07-02--2024-07-02
  • Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice.
    Clarin M.T.R.D.C.; E. Motoyama; A. Nabil; S. Kanki; U...
    International Vascular Biology Meeting 2024/2024-07-02--2024-07-05
  • A Smart Nanofiber-based Therapeutic Approach for Aortic Dissection by Targeting Sympathetic Innervation
    LI Kai; Kimura Kenichi; Motoyama Eri; Fujisawa Nanami...
    第56回日本結合組織学会学術大会/2024-06-15--2024-06-16
  • Nanoparticles as a potential therapeutic tool for targeting M1 macrophages in Aortic Dissection
    Cruz Maria Thea Rane Dela; Motoyama Eri; Ahmed Nabil; ...
    第56回日本結合組織学会学術大会/2024-06-15--2024-06-16
  • Fibrillin-1 G234D mutation links mouse skin tightness to elastic fiber defects and collagen cross-linking
    Hossain ASM Sakhawat; Cruz Maria Thea Rane Dela; Kimura...
    第56回日本結合組織学会学術大会/2024-06-15--2024-06-16
  • Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis
    Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
    第56回日本結合組織学会学術大会/2024-06-15--2024-06-16
  • Investigation of mechanosensing mechanisms in aortic dissection caused by a missense variant in the fibrillin-1
    本山 絵理; 木村 健一; Maria Thea Rane Dela Cruz Clarin; 浅野 恵一...
    第56回日本結合組織学会学術大会/2024-06-15--2024-06-16
  • Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice.
    Clarin M.T.R.D.C.; E. Motoyama; A. Nabil; S. Kanki; K...
    World Biomaterials Congress/2024-05-27--2024-05-31
  • 骨軟骨組織の維持・再生に関わる間葉系幹細胞の同定
    木村 健一
    第23回日本再生医療学会総会/2024-03-21--2024-03-23
  • Treatment for Aortic Dissection Using Nanoparticles to Target M1 Macrophages.
    Clarin M.T.R.D.C.; Motoyama E; Nabil A; Kanki S; Kimu...
    Tsukuba Biomedical Engineering Forum/2024-01-19
  • Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
    Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
    第7回日本循環器学会　基礎研究フォーラム（BCVR）/2023-12-09--2023-12-10
  • Cell Lineage Analysis of CD73-Positive Cells in the Bone Marrow Microenvironment
    木村 健一; Bernd Fleischmann; 柳沢 裕美
    第46回日本分子生物学会年会/2023-12-06--2023-12-08
  • Maintaining differentiated cell identity during aging -- insights from Drosophila enteroendocrine cells
    Qian Qingyin; Hayashi Makoto; Kimura Ken-ichi; Yanagis...
    第46回日本分子生物学会年会/2023-12-06--2023-12-08
  • A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype
    ASM Sakhawat Hossain; Maria Thea Rane Dela Cruz; Koichi...
    第7回エラスチン・関連分子研究会学術集会/2023-11-23--2023-11-24
  • 新規Fibrillin-1点変異マウスモデルを⽤いた⼤動脈解離発症機序の解明
    木村 健一
    第1回大動脈研究会/2023-11-18
  • A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype
    ASM Sakhawat Hossain; Yuki Taga; Maria Thea Rane Dela ...
    Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB, HCS, and ASIP/2023-10-23--2023-10-26
  • Investigation of the molecular mechanism of BAV-associated aortopathy
    Liu Chang; Tokunaga Chiho; Sugiyama Kaori; Kimura Ken...
    The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery/2023-10-19--2023-10-21
  • more...
Teaching
2024-10 -- 2025-02Practice in Diagnostic Pathology IUniversity of Tsukuba.
2024-04 -- 2024-08Practice in Diagnostic Pathology IUniversity of Tsukuba.
2024-04 -- 2024-08Lecture and Discussion in Human Medical Biology IUniversity of Tsukuba.
2024-10 -- 2025-02Lecture and Discussion in Human Medical Biology IIUniversity of Tsukuba.
2024-10 -- 2025-02Practice in Human Medical Biology IIUniversity of Tsukuba.
2024-10 -- 2025-02Practice in Diagnostic Pathology IIUniversity of Tsukuba.
2024-04 -- 2024-08Practice in Diagnostic Pathology IIUniversity of Tsukuba.
2024-10 -- 2025-02Seminar in Human Medical Biology IIUniversity of Tsukuba.
2024-04 -- 2024-08Medical Science Seminar V: Career PathUniversity of Tsukuba.
2024-10 -- 2025-02Medical Science Seminar V: Career PathUniversity of Tsukuba.
more...
Professional activities
2024-11 -- (current)THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE代議員
2022-08 -- (current)日本再生医療学会チームU45/サブメンバー
2022-11 -- (current)Jananese Society for Matirx Biology and Medicine若手の会/代表
University Management
2023-04 -- 2024-03TARAセンター仕様策定委員会委員
2021-04 -- (current)フロンティア医科学専攻キャリア支援担当委員会委員

(Last updated: 2024-11-13)