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Kaushik Mahesh Kumar

Affiliation
International Institute for Integrative Sleep Medicine
Official title
Assistant Professor
ORCID
0000-0003-4286-1573
Sex
Male
Other affiliation
The University of Tsukuba International Institute for Integrative Sleep MedicineAssistant Professor
Research keywords
Pre-clinical studies
Seizure/Epilepsy
Narcolepsy/Cataplexy
Neurobiology of sleep-wakefulness
CNS Disorders
Research projects
Investigating the effects of orexin antagonists on sleep disorder narcolepsy and underlying molecular and cellular changes in brain architecture2014-09 -- 2020-12/
Evaluation of the wake-inducing activity of novel compounds by Sumitomo Dainippon Pharma in murine models2018-01 -- 2019-01Sumitomo Dainipponn Pharma, Japan/5,000,000Yen
Development of therapy for the treatment of cataplexy/narcolepsy by intrathecal orexin administration2014-12 -- 2018-08/
Evaluation of novel compounds by MTPC for their wake-inducing potential and narcolepsy inhibiting activity in murine models.2017-01 -- 2018-01Mitsubishi Tanabe Pharma Co. (MTPC), Japan/10,000,000Yen
Role of Prostaglandin D2 in epileptic seizures and post-ictal pathological sleep regulation2011-01 -- 2018-01/
b. Identification and estimation of stress mitigating and sleep restoring potential of octacosanol2014-01 -- 2017-01/
Identification and evaluation of somnogenic components of Ashwagandha (Withania somnifera)2014-01 -- 2017-01/
Career history
2021-08 -- (current)University of Tsukuba, Tsukuba, Ibaraki, Japan International Institute for Integrative Sleep Medicine (IIIS). Assistant Professor
2014-09 -- 2021-07International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan Molecular Genetics of Sleep (Yanagisawa Lab). Researcher
2014-04 -- 2014-08Indiana University of School of Medicine, South Bend, IN, USA Department of Toxicology and Pharmacology. Postdoctoral Fellow
2013-03 -- 2013-12International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan Researcher
2011-03 -- 2013-02Osaka Bioscience Institute (OBI), Osaka, Japan Department of Molecular Sleep (2nd Department). Postdoctoral Fellow
Academic background
2005-02 -- 2010-12All India Institute of Medical Sciences (AIIMS), New Delhi, India. Department of Physiology. Ph.D.
2002-07 -- 2004-06Jiwaji University, Gwalior, Madhya pradesh, India School of Studies in Neuroscience. M.Sc.
1998-07 -- 2001-06Maharashi Dayananda University, Rohtak, Haryana Pt. Jawahar Lal Nahru College, Faridabad. B.Sc.
Academic societies
-- (current)Japanese Society for Sleep Research (JSSR)
-- (current)Indian Society for Sleep Research (ISSR)
-- (current)Association of Physiologists and Pharmacologist of India
-- (current)Indian Academy of Neuroscience
Honors & Awards
2011-03Takeda Science Foundation Award for Research In JapanPostdoctoral fellowship, Osaka Bioscience Institute (OBI), Osaka, Japan
2010-124th conference of Indian Society for Sleep Research (ISSR), Trivandrum, IndiaBest Paper Award, ISSR Conference
2009-12Travel AwardISN/APSN/IBRO/SNCI advance school on neurodegenerative diseases, Cochin, India
2008-07Travel AwardSwiss Society for Neuroscience
2007-08Joint Travel AwardWFSRS, Sleep Conference, Cairn, Australia
2009-10Travel Award6th Asian Sleep Research Society (ASRS) Conference, Osaka, Japan
2008-06Travel AwardISN/APSN/IBRO school, Fudan University, Shanghai, China
Refereed academic journal/Refereed international conference paper
Conference, etc.
  • Glutamate at medial preoptic area increases sleep
    K. Kaushik Mahesh
    Indian Society for Sleep Research conference, Bangalore, India/2007-07-01
  • Alteration in brain temperature, body temperature and sleep wakefulness during chronic cold exposure in rats
    Mahesh K. Kaushik
    Silver Jubilee Conference of Indian Academy of Neuroscience/2007-11-01
  • Changes in sleep-wakefulness after injection of glutamate at medial preoptic area
    Kaushik MK; Kumar VM; Mallick HN
    Asia Pacific Society of Neurochemistry Conference, Shanghai, China./2008-06-01
  • Glutamate at medial preoptic area increases sleep: A pilot study
    Kaushik MK; Kumar VM; Mallick HN
    FENS Forum of European Neuroscience, (12-16, 2008) Geneva, Switzerland/2008-08-01
  • Effect of lateral preoptic area lesion on sleep, hypothalamic and body temperature in rats
    Kaushik MK; Kumar VM; Mallick HN
    6th Asia Sleep Research Society (ASRS) Conference, Osaka, Japan/2009-10-24--2009-10-27
  • Effect of the lateral preoptic area lesion on sleep-wakefulness, hypothalamic and body temperature during chronic cold exposure
    K. Kaushik Mahesh
    ??/2010-12-13
  • The role of Prostaglandin D2 in causing post-ictal sleep following seizures
    K. Kaushik Mahesh
    WorldSleep2011, Wold Federation of Sleep Research and Sleep Medicine Societies, Kyoto, Japan/2011-10-01
  • The role of prostaglandin D2 in causing post-ictal sleep following seizures
    Mahesh K. Kaushik
    Indian Academy of neuroscience (IAN), Conference, DIPAS, New Delhi, India./2011-11-01
  • The role of prostaglandin D2 in seizures and post-ictal sleep
    MK Kaushik; M Lazarus; K Aritake; S Kamauchi; Y Cherasse;...
    Japanese Society for Sleep Research (JSSR) Annual Conference, (27-30 June, 2012) Yokohama, Japan/2012-06-01
  • The role of prostaglandin D2 in seizures and post-ictal sleep
    K. Kaushik Mahesh
    7th Asian Sleep Research Society (ASRS) conference, (Nov-Dec, 2012) Taipei, Taiwan./2012-11--2012-12
  • Prostaglandin D2: role in seizure suppression and postictal sleep
    Kaushik Mahesh Kumar
    5th DAILAB Café, AIST, Tsukuba, Japan/2014-11-17
  • Prostaglandin D2 is crucial for seizure suppression and postictal sleep
    Mahesh K. Kaushik
    Indian Scientists Association in Japan (ISAJ)” symposium, Tokyo, Japan/2014-12-01
  • Identification of somnogenic component of Ashwagandha (Withania somnifera) leaf
    Kaushik MK; Sunil C. Kaul; Renu Wadhwa; Urade Y
    6th World Congress on Sleep Medicine (WASM), Seoul, Korea/2015-03-21--2015-03-25
  • Somnogenic component of Ashwagandha: an alternative insomnia therapy
    K. Kaushik Mahesh
    Indian Academy of neuroscience (IAN), Conference, NBRC, Manesar, Haryana, India/2016-10-19--2016-10-21
  • Chronic orexin antagonist suvorexant administration induces sleep and cataplexy in mice
    K. Kaushik Mahesh
    Silver Jubilee Conference of Indian Society for Sleep Research (ISSR), (22-23 Sep, 2017), Goa, India/2017-09-22--2017-09-23
  • Why do need to sleep? The biggest mystery of neuroscience
    Mahesh K. Kaushik
    DAICENTER DAILAB PIKNIKH Series XXVII, AIST, Tsukuba, Japan (Oct 17, 2018)/2018-10-17
  • Sleep need and its relation to neurological disorders
    Mahesh K. Kaushik
    Indian Scientists Association in Japan (ISAJ)” symposium, AIST, Tsukuba, Japan/2018-12-07
  • Sleep and Narcolepsy- mysteries, mechanisms and manipulations
    Mahesh K. Kaushik
    PIKHNIKH, DAILAB, workshop, AIST, Tsukuba, Japan/2019-01-21
  • Chronic orexin receptor blockage induces Narcoleptic behavior by reducing orexin peptide synthesis in mice
    K. Kaushik Mahesh; Aritake Kosuke; Kakizaki Miyo; Kanbaya...
    WorldSleep 2019, Vancouver, Canada./2019-09-22--2019-09-25
  • Solving the mysteries of sleep: The role of the orexinergic system in sleep and narcolepsy
    Mahesh K. Kaushik
    PIKHNIKH, DAILAB, workshop, AIST, Tsukuba, Japan. (October 08, 2019)/2019-10-08
Talks
  • Novel therapy for narcolepsy by intrathecal orexin slow infusion in the murine model
    Mahesh K. Kaushik
    Department of Physiology, All India Institute of Medical Sciences, New Delhi, India/2016-03-04
  • Prostaglandin D2 (PGD2) in sleep and seizures
    K. Kaushik Mahesh
    Department of Physiology, All India Institute of Medical Sciences, New Delhi/2016-10-17
  • Role of Prostaglandin D2 (PGD2) in sleep and seizures
    Mahesh K. Kaushik
    SOS Neuroscience, Jiwaji University, Gwalior, Indi/2016-10-25
  • Orexin antagonist in sleep promotion: problems and warning
    K. Kaushik Mahesh
    Organized by Akita University, sponsored by Eisai Pharma, Japan (Feb 01, 2017)/2017-02-01
  • Orexin and its antagonist in sleep and narcolepsy
    Mahesh K. Kaushik
    All India Institute of Medical Sciences (AIIMS), Jodhpur, India (Sep 25, 2017)/2017-09-25
  • Development of treatment for narcolepsy by continues intrathecal orexin administration
    Mahesh K. Kaushik
    Department of Physiology, All India Institute of Medical Sciences (AIIMS), New Delhi/2018-10-27
  • Orexin and orexin receptors in sleep/wake regulation and narcolepsy
    Mahesh K. Kaushik
    SRI International, Menlo Park, CA, USA./2020-02-07
  • Solving the mysteries of sleep
    Mahesh K. Kaushik
    International Webinar series-1, Integrated Association of Medical, Basic and Social Scientists (IAMBSS)/2020-08-27
  • Role of orexins/hypocretins in sleep/wake regulation and narcolepsy
    Mahesh K. Kaushik
    DAILAB, CAFE, AIST, Tsukuba, Japan/2021-01-14

(Last updated: 2021-10-29)