FUJIMAKI Motoki

Affiliation
Institute of Medicine
Official title
Assistant Professor
ORCID
0009-0007-6766-5145
Sex
Male
Birth date
1983-07
KAKEN ID
10961708
Email
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Research fields
Experimental pathology
Neurology
Research keywords
Neuronal degenerative diseases
Neurodegeneration with Brain Iron Accumulation (NBIA)
Autophagy
Novel drug seeds
Ferroptosis
Research projects
Elucidation and Clinical Application of the Relationship Between Sleep Disorders and Neuroimmunological Pathology Based on a Personalized Pathophysiological Model of Myasthenia Gravis2025-10 -- 2028-03Motoki FujimakiJapan Agency for Medical Research and Development (AMED)/Medical Research Support Program45,000,000Yen
Development of novel curative seeds for pantothenate kinase–associated neurodegeneration based on inhibition of alpha-synuclein–polyunsaturated fatty acid binding2025-04 -- 2028-03Motoki FujimakiThe Japan Agency for Medical Research and Development (AMED)/Research grant on rare and intractable diseases Program39,000,000Yen
Are brain iron accumulation and neuronal death in β-propeller–associated neurodegeneration caused by ferroptosis?2023-04 -- 2028-03Motoki FujimakiJapan Society for the Promotion of Science/Grant-in-Aid for Early-Career Scientists4,550,000Yen
Exploratory study for curative therapeutic strategies in β-propeller protein–associated neurodegeneration2024-12 -- 2026-03Motoki FujimakiMochida Memorial Foundation for Medical and Pharmaceutical Research/Research Grant3,000,000Yen
Is dopaminergic neuronal death in Parkinson’s disease caused by iron-related cell death ferroptosis?2024-09 -- 2029-03Motoki FujimakiTakeda Science Foundation/Research Grant2,000,000Yen
Overseas Research Fellowship Grant (University of Cambridge)2019-04 -- 2022-03Motoki FujimakiTakeda Science Foundation/Overseas Research Fellowship Grant15,000,000Yen
Career history
2024-04 -- (current)Faculty of Medicine, University of TsukubaDepartment of NeurologyAssistant Professor
2023-12 -- 2024-03University of Tsukuba HospitalAssistant Professor
2022-03 -- 2023-11Shizuoka Hospital, Faculty of Medicine, Juntendo UniversityAssistant Professor
2019-04 -- 2022-03ケンブリッジ大学 ケンブリッジ医学生物学研究所Cambridge Institute for Medical Research, University of CambridgeResearch Associate
2012-04 -- 2015-03Faculty of Medicine, Juntendo UniversityDepartment of NeurologyStaff Physician
2010-04 -- 2012-03Juntendo University Hospital, Faculty of Medicine, Juntendo UniversityJunior Resident
Academic background
2015-04 -- 2019-03Graduate School of Medicine, Juntendo University Doctoral Program Completed (Ph.D. in Medicine)
2004-04 -- 2010-03Faculty of Medicine, University of Yamanashi Graduated (M.D.)
Degree
2019-03Ph.D. in MedicineJuntendo University
Licenses and qualifications
2023-04medical instructor (The Japanese Society of Neurology)
2016-07Specialty of Clinical Neuurology (The Japanese Society of Neurology)
2010-04medical license
Academic societies
2012-04 -- (current)THE JANPANESE SOCIETY OF INTERNAL MEDICINE
2012-04 -- (current)The Japanese Society of Neurology
Honors & Awards
2024-092024 Japan Medical Association Medical Research Encouragement AwardExploration of curative therapies for β-propeller protein–associated neurodegeneration (BPAN) through regulation of autophagy-independent ferroptosis
2024-05Best Oral Presentation Award (Basic Section)Best oral presentation in the basic section at the 65th Annual Meeting of the Japanese Society of Neurology/AOCN2024
2017-09Excellent Presentation AwardExcellent presentation at the 59th Annual Meeting of the Japanese Society of Neurology
2014-10Excellence AwardExcellent presentation at the 8th Congress of the Japanese Society of Parkinson’s Disease and Movement Disorders
Articles
Books
  • Alterations in Caffeine Metabolism in Parkinson’s Disease and Their Diagnostic Implications
    藤巻 基紀
    CMC Publishing Co., Ltd., 2018-09
  • Protein degradation systems and Parkinson’s disease
    藤巻 基紀
    The Japanese Journal of Clinical Medicine, August 2023 Special Issue: Parkinson’s Disease 2023 — Recent Advances in Basic and Clinical Research —/Nippon Rinsho Co., Ltd./pp.1329-1335, 2023-08
  • From Metabolomics to Drug Discovery in Parkinson’s Disease
    藤巻 基紀
    Neurology, Vol. 100, No. 4/Kagaku Hyoronsha Co., Ltd./pp.1-6, 2024-04
Conference, etc.
  • Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis
    FUJIMAKI Motoki
    The 65th Annual Meeting of the Japanese Society of Neurology / Asian and Oceanian Congress of Neurology 2024/2024-05-29--2024-06-01
Teaching
2025-10 -- 2025-12Understanding of neurological diseasesUniversity of Tsukuba.
2024-09 -- (current)Peripheral Nerve and Muscle DisordersFaculty of Medicine, University of Tsukuba
2024-09 -- (current)Disorders with Cerebellar Ataxia as the Main SymptomFaculty of Medicine, University of Tsukuba
2024-09 -- (current)Motor Neuron Diseases and Spinocerebellar DegenerationFaculty of Medicine, University of Tsukuba
2024-09 -- (current)Central Nervous System PharmacologyFaculty of Medicine, University of Tsukuba
2024-09 -- (current)Understanding Neuroimmunological Disorders from a Therapeutic PerspectiveFaculty of Medicine, University of Tsukuba

(Last updated: 2025-10-03)