HAMA Yutaro

Affiliation

Institute of Life and Environmental Sciences

Official title

Junior Assistant Professor

Sex

Male

Research fields

Molecular biology
Cell biology
Structural biochemistry
Evolutionary biology

Research keywords

Autophagy
Cell Biology
Structural Biology
Protein Structure Prediction

Research projects

祖先的オートファジー始動メカニズムとその哺乳類・出芽酵母に至る進化過程の解明	2023-04 -- 2026-03	濱　祐太郎	JSPS/若手研究	4,680,000Yen

Career history

2026-01 -- (current)	筑波大学生命環境系特任助教（奨励）
2025-04 -- 2025-12	北海道大学遺伝子病制御研究所　生命分子機構分野博士研究員
2022-04 -- 2025-03	北海道大学遺伝子病制御研究所　生命分子機構分野日本学術振興会特別研究員PD
2021-04 -- 2022-03	東京大学大学院医学系研究科　分子生物学分野特任研究員

Academic background

2017-04 -- 2021-03	東京大学 大学院医学系研究科 分子細胞生物学専攻　博士課程
2015-04 -- 2017-03	東京大学 大学院医学系研究科 医科学専攻　修士課程
2011-04 -- 2015-03	東海大学 工学部 生命化学科

Degree

2021-03	博士（医学）	東京大学

Articles

• Linear ubiquitination triggers Amph-mediated T-tubule biogenesis
  Kawaguchi Kohei; Hama Yutaro; Yoshikawa Harunori; Nish...
  Science advances/12(2)/p.eady4934, 2026-01-09
  
  PubMed
• Evolutionary diversification of the autophagy initiation complex: reduced Atg101 dependency and changes in Atg9 binding to Atg13
  Lai Zefeng; Hama Yutaro; Oku Masahide; Zhang Sidi; Sa...
  Autophagy/21(12)/pp.3039-3056, 2025-12-01
  
  PubMed
• The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy
  Hama Yutaro; Fujioka Yuko; Yamamoto Hayashi; Mizushima...
  eLife/13, 2025-06-24
  
  PubMed
• Mechanisms of mitochondrial reorganization
  Maruyama Tatsuro; Hama Yutaro; Noda Nobuo N
  Journal of biochemistry/175(2)/pp.167-178, 2024-02-25
  
  PubMed
• Autophagy and cancer: Basic mechanisms and inhibitor development
  Hama Yutaro; Ogasawara Yuta; Noda Nobuo N
  Cancer science/114(7)/pp.2699-2708, 2023-07-01
  
  PubMed
• Regulation of ER-derived membrane dynamics by the DedA domain-containing proteins VMP1 and TMEM41B
  Hama Yutaro; Morishita Hideaki; Mizushima Noboru
  EMBO reports/23(2), 2022-02-03
  
  PubMed
• The evolution of autophagy proteins - diversification in eukaryotes and potential ancestors in prokaryotes
  Zhang Sidi; Hama Yutaro; Mizushima Noboru
  Journal of cell science/134(13), 2021-07-01
  
  PubMed
• ZZ domains keep cytosol to vacuole delivery whiZZing along
  Hama Yutaro; Zhang Sidi; Mizushima Noboru
  The EMBO journal/40(15), 2021-08-02
  
  PubMed
• Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1
  Okawa Fumiya; Hama Yutaro; Zhang Sidi; Morishita Hide...
  Journal of cell science/134(8), 2021-04-15
  
  PubMed
• SQSTM1^L341V variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells
  Nozaki Masahisa; Otomo Asako; Mitsui Shun; Ono Suzuka...
  eNeurologicalSci/22, 2021-03-01
  
  PubMed
• TMEM41B functions with VMP1 in autophagosome formation
  Morita Keigo; Hama Yutaro; Mizushima Noboru
  Autophagy/15(5)/pp.922-923, 2019-05-01
  
  PubMed
• Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation
  Morita Keigo; Hama Yutaro; Izume Tamaki; Tamura Norit...
  The Journal of cell biology/217(11)/pp.3817-3828, 2018-11-05
  
  PubMed
• A new probe to measure autophagic flux in vitro and in vivo
  Morishita Hideaki; Kaizuka Takeshi; Hama Yutaro; Mizus...
  Autophagy/13(4)/pp.757-758, 2017-04-03
  
  PubMed
• An Autophagic Flux Probe that Releases an Internal Control
  Kaizuka Takeshi; Morishita Hideaki; Hama Yutaro; Tsuka...
  Molecular cell/64(4)/pp.835-849, 2016-11-17
  
  PubMed

(Last updated: 2026-01-07)