FURUYAMA Wakako

Affiliation

Institute of Medicine

Official title

Specially Appointed Associate Professor

Research fields

Virology
Veterinary medical science

Research keywords

フィロウイルス
細胞内輸送
治療法開発

Research projects

エボラウイルス分泌型糖タンパク質の出血性病態に対する機能解明	2026-04 -- 2029-03	古山若呼	日本学術振興会　科学研究費補助金/基盤研究C	6,110,000Yen
新興ナイロウイルスの病原性発現機構の解明	2026-04 -- 2031-03	松野啓太	日本学術振興会　科学研究費補助金/基盤研究A	41,990,000Yen
生体膜動態に基づくエボラウイルス粒子形成機構の解明	2024-04 -- 2027-03	南保明日香	日本学術振興会　科学研究費補助金/基盤研究B	17,030,000Yen
エボラウイルス分泌型糖タンパク質sGPの血管内皮細胞における機能解析	2024-01 -- 2024-12	古山若呼	シオノギ感染症研究振興財団/次世代育成支援研究助成金	3,000,000Yen
エボラウイルス分泌型糖タンパク質sGPの生体内動態と病原性発現分子機構の解明	2022-04 -- 2027-03	古山若呼	武田科学振興財団/2022年度「医学系研究助成(感染領域)」	2,000,000Yen
エボラウイルス分泌型タンパク質のMylc細胞における分泌機構の解明	2022-04 -- 2023-03	古山若呼	株式会社リバネス/第55回リバネス研究費マイキャン・テクノロジーズ賞	300,000Yen
エボラウイルス分泌型糖タンパク質sGPの病原性発現分子機構の解明	2022-04 -- 2026-03	古山若呼	日本学術振興会 科学研究費助成事業/若手研究	4,550,000Yen
複製可能な蛍光エボラウイルス様粒子の作出と性状解析	2021-08 -- 2023-03	古山若呼	日本学術振興会 科学研究費助成事業/研究活動スタート支援	3,120,000Yen
1 分子解析技術に基づくエボラウイルス粒子形成機構の解明と新規治療法の開発	2020-04 -- 2023-03	南保明日香	日本医療研究開発機構/新興・再興感染症研究基盤創生事業多分野融合研究領域	30,940,000Yen
エボラウイルス感染における「抗体依存性感染増強現象」の分子メカニズムの解明	2014-04 -- 2017-03	古山若呼	日本学術振興会 科学研究費助成事業/特別研究員奨励費 (DC1)	3,200,000Yen

Career history

2026-04 -- (current)	筑波大学　医学医療系特任准教授
2021-04 -- 2026-03	長崎大学　高度感染症研究センター　研究部門助教
2019-03 -- 2021-02	Rocky Mountain Laboratories (RML), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH).日本学術振興会KAITOKU-NIH特別研究員
2017-06 -- 2019-02	Rocky Mountain Laboratories (RML), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH).Visiting Fellow
2017-04 -- 2017-05	北海道大学　人獣共通感染症国際共同研究所国際疫学部門博士研究員
2014-04 -- 2017-03	独立行政法人日本学術振興会 (JSPS)特別研究員（DC1）

Academic background

2013-04 -- 2017-03	北海道大学大学院 獣医学研究科
2007-04 -- 2013-03	帯広畜産大学 畜産学部 獣医学科

Degree

2017-03	博士（獣医学)	北海道大学

Licenses and qualifications

2013-03	獣医師

Academic societies

2015-10 -- (current)	日本ウイルス学会

Honors & Awards

2025-03	優秀ポスター賞
2023-12	第8回長崎大学 未来に羽ばたく女性研究者賞 優秀女性奨励賞
2022-04	マイキャン・テクノロジーズ賞
2021-09	若手奨励賞
2021	NIH director’s award
2020	NIAID Merit ward
2019	The NIH Fellows Award for Research Excellence (FARE) 2019
2017-03	北海道大学大塚賞2017

Articles

• Griffithsin-mediated inhibition of cellular entry of hemorrhagic fever viruses and insights into its mechanisms
  Saito Takeshi; Furuyama Wakako; Muthusinghe Devinda S; ...
  Journal of virology, 2026-04-27
  
  PubMed
• Low-dose VSV-EBOV vaccination provides rapid protection from lethal Ebola virus challenge
  Marzi Andrea; Furuyama Wakako; Griffin Amanda J; Feldm...
  bioRxiv : the preprint server for biology, 2026-02-15
  
  PubMed
• Discovery of potent cross-neutralizing antibodies against Marburg and Ravn viruses with therapeutic potential
  Saito Takeshi; Miyamoto Hiroko; Igarashi Manabu; Nanbo...
  Npj viruses/3(1)/p.84, 2025-12-27
  
  PubMed
• Development of a Novel, Highly Sensitive System for Evaluating Ebola Virus Particle Formation
  Furuyama Wakako; Sakaguchi Miako; Ariyoshi Hanako; Nan...
  Viruses/17(7), 2025-07-19
  
  PubMed
• Visualizing the Internalization of Marburg Viruslike Particles into Living Cells
  Nanbo Asuka; Sakaguchi Miako; Furuyama Wakako
  Methods in molecular biology (Clifton, N.J.)/2877/pp.75-90, 2025-04-01
  
  PubMed
• Quantification of Filovirus Soluble Glycoprotein Using a Sandwich ELISA
  Furuyama Wakako; Nanbo Asuka
  Methods in molecular biology (Clifton, N.J.)/2877/pp.409-419, 2025-04-01
  
  PubMed
• Marburg virus exploits the Rab11-mediated endocytic pathway in viral-particle production
  Furuyama Wakako; Yamada Kento; Sakaguchi Miako; Marzi ...
  Microbiology spectrum/12(9), 2024-09-03
  
  PubMed
• Micro-second time-resolved X-ray single-molecule internal motions of SARS-CoV-2 spike variants
  Sasaki Daisuke; Arai Tatsuya; Yang Yue; Kuramochi Mas...
  Biochemistry and biophysics reports/38, 2024-07-01
  
  PubMed
• A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus
  Ng Tony W; Furuyama Wakako; Wirchnianski Ariel S; Saav...
  bioRxiv : the preprint server for biology, 2024-05-29
  
  PubMed
• Mapping of susceptibility loci for Ebola virus pathogenesis in mice
  Schäfer Alexandra; Marzi Andrea; Furuyama Wakako; Cata...
  Cell reports/43(5), 2024-05-28
  
  PubMed
• Phylogenetic analysis of the promoter element 2 of paramyxo- and filoviruses
  Ashida Shoichi; Kojima Shohei; Okura Takashi; Kato Fu...
  Microbiology spectrum/12(5), 2024-05-02
  
  PubMed
• A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus
  Ng Tony W; Furuyama Wakako; Wirchnianski Ariel S; Saav...
  Frontiers in immunology/15, 2024-04-01
  
  PubMed
• A Single Case Observation: Is the Ebola Virus Soluble Glycoprotein an Indicator of Viral Recrudescence?
  Furuyama Wakako; Davey Richard T; Chertow Daniel S; Ma...
  The Journal of infectious diseases/228(Suppl 7)/p.S631-S634, 2023-11-13
  
  PubMed
• Atypical Ebola Virus Disease in a Rhesus Macaque
  Marzi Andrea; Hanley Patrick W; Furuyama Wakako; Haddo...
  The Journal of infectious diseases/228(Suppl 7)/p.S617-S625, 2023-11-13
  
  PubMed
• Multiple Routes of Antibody-Dependent Enhancement of SARS-CoV-2 Infection
  Okuya Kosuke; Hattori Takanari; Saito Takeshi; Takadat...
  Microbiology spectrum/10(2), 2022-04-27
  
  PubMed
• [Introduction of high containment laboratories in abroad]
  Furuyama Wakako; Nanbo Asuka
  Uirusu/72(2)/pp.139-148, 2022-04-01
  
  PubMed
• A platform technology for generating subunit vaccines against diverse viral pathogens
  Young Andrew; Isaacs Ariel; Scott Connor A P; Modhiran...
  Frontiers in immunology/13, 2022-04-01
  
  PubMed
• Development of an imaging system for visualization of Ebola virus glycoprotein throughout the viral lifecycle
  Furuyama Wakako; Sakaguchi Miako; Yamada Kento; Nanbo ...
  Frontiers in microbiology/13, 2022-04-01
  
  PubMed
• VSV-Based Vaccines Reduce Virus Shedding and Viral Load in Hamsters Infected with SARS-CoV-2 Variants of Concern
  O'Donnell Kyle L; Gourdine Tylisha; Fletcher Paige; Sh...
  Vaccines/10(3), 2022-03-12
  
  PubMed
• Rapid Protection from COVID-19 in Nonhuman Primates Vaccinated Intramuscularly but Not Intranasally with a Single Dose of a Vesicular Stomatitis Virus-Based Vaccine
  Furuyama Wakako; Shifflett Kyle; Pinski Amanda N; Grif...
  mBio/13(1), 2022-02-22
  
  PubMed
• Recombinant protein subunit SARS-CoV-2 vaccines formulated with CoVaccine HT adjuvant induce broad, Th1 biased, humoral and cellular immune responses in mice
  Lai Chih-Yun; To Albert; Ann S Wong Teri; Lieberman M...
  Vaccine: X/9, 2021-11-05
  
  PubMed
• Optimization of single dose VSV-based COVID-19 vaccination in hamsters
  O'Donnell Kyle L; Clancy Chad S; Griffin Amanda J; Shi...
  bioRxiv : the preprint server for biology, 2021-09-03
  
  PubMed
• The Ebola virus soluble glycoprotein contributes to viral pathogenesis by activating the MAP kinase signaling pathway
  Furuyama Wakako; Shifflett Kyle; Feldmann Heinz; Marzi...
  PLoS pathogens/17(9), 2021-09-01
  
  PubMed
• Ebola Virus Glycoprotein Domains Associated with Protective Efficacy
  Bhatia Bharti; Furuyama Wakako; Hoenen Thomas; Feldman...
  Vaccines/9(6), 2021-06-10
  
  PubMed
• RNA Virus-Encoded miRNAs: Current Insights and Future Challenges
  Nanbo Asuka; Furuyama Wakako; Lin Zhen
  Frontiers in microbiology/12, 2021-04-01
  
  PubMed
• more...

(Last updated: 2026-05-08)