AKAMA Yuichi

Affiliation
Institute of Medicine
Official title
Specially Appointed Assistant Professor
ORCID
0000-0002-7040-1307
Email
)Pb8B8D8ZieD;cKJLBL98c8:cAG
Research keywords
innate lymphoid cell
sepsis
PD-1
Skeletal muscle
Lung
好中球
CD300LD
Precision Immunotherapy
Research projects
敗血症における自然リンパ球制御異常の解明2018-04 -- 2019-03赤間 悠一三重大学/平成30年度新研究プロジェクト0Yen
敗血症性肺障害における2型自然リンパ球の炎症制御機構2019-04 -- 2020-03赤間 悠一岡三加藤文化振興財団/
The trafficking and effector function of the group 2 innate lymphoid cells in sepsis-induced lung injury2019-04 -- 2021-03Akama YuichiJapan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists4,290,000Yen
Innate lymphoid cells suppress atrophy of skeletal muscle: A novel therapeutic target for sepsis survivor2021-11 -- 2023-03赤間悠一Takeda Science Foundation/
Aberrant skeletal muscle-brain communication in sepsis-associated encephalopathy: Elucidating the pathogenic roles of skeletal muscle-derived exosomes2019-10 -- 2024-03川本 英嗣; 亀井 政孝; 赤間 悠一; 中森 裕毅; 池尻 薫Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))18,200,000Yen
ILC2 exhaustion and metabolic dysregulation in septic myopathy: implications of PD-L1 exosomes2021-04 -- 2024-03赤間 悠一Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)4,160,000Yen
Elucidation of the mechanism by which exosomal PD-L1 induces septic immune paralysis2021-04 -- 2024-03川本 英嗣; 島岡 要; 朴 恩正; 赤間 悠一; 高娃 阿栄Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)4,160,000Yen
Study of the roles played by exosomal microRNAs of intestinal epithelial cells in downregulating septic inflammations2022-04 -- 2025-03朴 恩正; 川本 英嗣; 島岡 要; 赤間 悠一; 高娃 阿栄Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)4,290,000Yen
間質性肺炎急性増悪の新規メカニズム:エクソソーム型サイトカインによる線維化作用2022-04 -- 2025-03伊藤 温志; 島岡 要; 赤間 悠一; 佐藤 尚子日本学術振興会/科学研究費助成事業 基盤研究(C)4,290,000Yen
Elucidation of the molecular mechanism by which eosinophil-derived exosomes cause ICU delirium2025-04 -- 2029-03奥野 郁斗; 川本 英嗣; 島岡 要; 赤間 悠一; 賀来 隆治Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research4,680,000Yen
Career history
2013-04 -- 2016-03Nippon Medical School HospitalSurgery
2015-04 -- 2016-03Chiba Hokusoh HospitalSurgeryassistant professor
2016-04 -- 2018-03Aizu Chuo Hospitalsurgery医員
2018-04 -- 2022-09Mie University HospitalEmergency and Critical Care Centerassistant professor
2022-10 -- 2023-03The Feinstein Institute for Medical Research博士研究員
2026-05 -- 9999University of Tsukuba救急・集中治療医学特任講師
Academic background
2005-04 -- 2011-03Nippon Medical School Medical School
2018-04 -- 2022-03Mie University Graduate School of Medicine 分子病態学
Degree
2022-03Ph.D. in Medical ScienceMie University
Academic societies
2011-05 -- 9999日本外科学会
2013-04 -- 9999日本救急医学会
2013-04 -- 9999日本消化器外科学会
2013-04 -- 9999日本消化器病学会
2013-04 -- 9999日本腹部救急医学会
2020-01 -- 9999日本感染症学会
2020-04 -- 9999日本ショック学会
Honors & Awards
2022-03Salutatorian (graduated second in my class)
2022-03President’s Award
2022-03三重大学優秀論文・著書・作品賞 | Sepsis Induces Deregulation of IL-13 Production and PD-1 Expression in Lung Group 2 Innate Lymphoid Cells
2022-06Encouragement Award
2024-12Young Investigator Award
2025-05Finalist for Northwell’s 14th Annual Surgical Research Forum, 2025CD300LD Activation Enhances Neutrophil Phagocytosis to Reduce Bacterial Burden in Sepsis
2025-06Travel AwardA Novel Peptide Targeting Neutrophil-Mediated B-1a Cell Trogocytosis Attenuates Sepsis-Induced Organ Injury
2026-05Travel Award | A Novel Neutrophil Subtype Expressing CD40L Causes Brain Dysfunction in Intestinal Inflammation

(Last updated: 2026-05-02)