MUKAI Jun
- Affiliation
- University of Tsukuba
- Official title
- Professor
- Research fields
General physiology - Research keywords
Precision medicine Neuroscience, Psychiatry, 22q11.2 deletion syndrome, schizophrenia, Autism, Neurodevelopmental disease, Histone methylation - Research projects
統合失調症のエピゲノム分子病態 2023-09 -- 2027-03 MUKAI Jun Japan Society for the Promotion of Science/Fund for the Promotion of Joint International Research (International Collaborative Research) 20,800,000Yen Elucidation of pathological neural circuit formation mechanism for early therapeutic intervention of cognitive dysfunction in psychiatric disease. 2022-04 -- 2025-03 MUKAI Jun Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 17,420,000Yen Decifering the role of histone methyltransferase Setd1a in schizophrenia 2019-04 -- 2022-03 MUKAI Jun Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 17,420,000Yen - Career history
2018-07 -- (current) University of TsukubaResearch and Development Center for Precision MedicineProfessor - Degree
1995-03 医学博士 三重大学 - Articles
- Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a(+/-) Mice
Hamm Jordan P.; Shymkiv Yuriy; Mukai Jun; Gogos Joseph A...
Biological Psychiatry in Press (https://www.biologicalpsychiatryjournal.com/article/S0006-3223(20)30009-3/fulltext)/88(3)/pp.215-223, 2020-08 - Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice.
向井 淳; Cannavo E.; Sun Z.; Crabtree G.; Diamantopoulou A....
Neuron/104(3)/pp.471-487, 2019 - Loss-of-function mutation in rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion
Diamantopoulou Anastasia; Sun Ziyi; Mukai Jun; Xu Bin...
Proceedings of the National Academy of Sciences of the United States of America/114(30)/p.E6127-E6136, 2017-04 - Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition
Tamura Makoto; Mukai Jun; Gordon Joshua A; Gogos Jose...
Neuron/89(5)/pp.1100-1109, 2016-03 - Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome
Piskorowski Rebecca A; Nasrallah Kaoutsar; Diamantopoul...
Neuron/89(1)/pp.163-176, 2016-01 - Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia
Mukai Jun; Tamura Makoto; Fénelon Karine; Rosen Andre...
Neuron/86(3)/pp.680-695, 2015-05 - S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95
Ho Gary P H; Selvakumar Balakrishnan; Mukai Jun; Heste...
Neuron/71(1)/pp.131-141, 2011-07 - Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex
Fénelon Karine; Mukai Jun; Xu Bin; Hsu Pei-Ken; Drew ...
Proceedings of the National Academy of Sciences of the United States of America/108(11)/pp.4447-4452, 2011-03 - Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion
Mukai Jun; Dhilla Alefiya; Drew Liam J; Stark Kimberl...
Nature neuroscience/11(11)/pp.1302-1310, 2008-11 - Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
Paterlini Marta; Zakharenko Stanislav S; Lai Wen-Sung; ...
Nature neuroscience/8(11)/pp.1586-1594, 2005-11 - Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia
Mukai Jun; Liu Hui; Burt Rachel A; Swor Dionne E; Lai...
Nature genetics/36(7)/pp.725-731, 2004-07
- Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a(+/-) Mice
(Last updated: 2024-10-24)