ASANO Keiichi
- Affiliation
- Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
- Official title
- Assistant Professor
- ORCID
- 0009-0000-1065-6386
- URL
- Research fields
Pathological medical chemistry - Research keywords
Marfan syndrome Single Cell Analyses Extracellular matrix Vascular biology Aortic aneurysm and dissection - Research projects
平滑筋細胞の形質転換は大動脈瘤の新規治療標的となりうるか? 2024-04 -- 2028-03 ASANO Keiichi Japan Society for the Promotion of Science/Grant-in-Aid for Early-Career Scientists 4,680,000Yen - Career history
2023-04 -- (current) University of TsukubaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)Assistant Professor 2018-04 -- 2023-03 Icahn School of Medicine at Mount SinaiDepartment of Pharmacological SciencesPostdoctoral Researcher 2018-04 -- 2019-03 Okayama UniversityMedical SchoolGuest Investigator - Academic background
-- 2018-03 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences - Degree
2018-03 PhD in Medical Science Okayama University - Academic societies
2015 -- (current) Jananese Society for Matirx Biology and Medicine 2022 -- (current) North American Vascular Biology Organization - Honors & Awards
2014-06 Young Investigator Award 2021-09 Marfan Foundation Travel Award - Articles
- Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice
Hossain ASM Sakhawat; Clarin Maria Thea Rane Dela Cruz; ...
MATRIX BIOLOGY, 2024-11 - A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta
Kimura Kenichi; Motoyama Eri; Kanki Sachiko; Asano Ke...
Biorxiv, 2024-05-07 - Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells
Sun Yifei; Asano Keiichi; Sedes Lauriane; Cantalupo A...
JCI insight, 2023-04-06 - The Multiple Functions of Fibrillin-1 Microfibrils in Organismal Physiology
Asano Keiichi; Cantalupo Anna; Sedes Lauriane; Ramirez...
International journal of molecular sciences/23(3), 2022-02-08 - Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome
Asano Keiichi; Cantalupo Anna; Sedes Lauriane; Ramirez...
Biomolecules/12(1), 2022-01-14 - Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1
Ohtsuki Takashi; Shinaoka Akira; Kumagishi-Shinaoka Ka...
Experimental cell research/383(2), 2019-10-15 - High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression
Ohtsuki Takashi; Asano Keiichi; Inagaki Junko; Shinaok...
Journal of orthopaedic research : official publication of the Orthopaedic Research Society/36(12)/pp.3247-3255, 2018-12-01 - Host-produced ADAMTS4 Inhibits Early-Stage Tumor Growth
Asano Keiichi; Edamatsu Midori; Hatipoglu Omer F; Inag...
Acta medica Okayama/72(3)/pp.257-266, 2018-06-01 - Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis
Asano Keiichi; Nelson Courtney M; Nandadasa Sumeda; Ar...
Scientific reports/7(1), 2017-12-08 - ADAMTS1 inhibits lymphangiogenesis by attenuating phosphorylation of the lymphatic endothelial cell-specific VEGF receptor
Inagaki Junko; Takahashi Katsuyuki; Ogawa Hiroko; Asan...
Experimental cell research/323(2)/pp.263-275, 2014-05-01 - Induction of CEMIP in Chondrocytes by Inflammatory Cytokines: Underlying Mechanisms and Potential Involvement in Osteoarthritis
Ohtsuki Takashi; Hatipoglu Omer F; Asano Keiichi; Inag...
International journal of molecular sciences/21(9), 2020-04-29 - Fibrillin-1 deficiency in the outer perichondrium causes longitudinal bone overgrowth in mice with Marfan syndrome.
Asano Keiichi
Human Molecular Genetics, 2022
- Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice
- Books
- マルファン症候群における大動脈瘤・解離の研究の動向—シングルセル技術の視点から
浅野 恵一
生体の科学 75巻4号/pp.342-347, 2024-08 - 座談会 エキスパートが語るシングルセル研究のリアル
浅野 恵一
実験医学別冊 実験デザインからわかる シングルセル研究実践テキスト/羊土社, 2024-03-11
- マルファン症候群における大動脈瘤・解離の研究の動向—シングルセル技術の視点から
- Conference, etc.
- Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
Kimura Kenichi; Motoyama Eri; Kanki Sachiko; Asano Ke...
CVMW 2024/2024-12-07--2024-12-08 - 遺伝性胸部大動脈疾患におけるメカノトランスダクション異常
柳沢裕美; 木村健一; 本山絵理; 浅野恵一; 神吉佐知子
CVMW 2024/2024-12-07--2024-12-08 - フィブリリン1遺伝子変異による大動脈解離病態に関わる血管内皮細胞の機能解析
本山 絵理; 木村 健一; 浅野 恵一; 神吉 佐知子; 中邨 智之; 柳沢 裕美
第8回エラスチン・関連分子研究会/2024-11-30--2024-12-01 - Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
Kimura Kenichi; Motoyama Eri; Kanki Sachiko; Asano Ke...
第47回日本分子生物学会年会/2024-11-27--2024-11-29 - Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
Tsukuba Global Science Week 2024/2024-10-03--2024-10-04 - Nanoparticles as a potential therapeutic tool for targeting M1 macrophages in Aortic Dissection
Cruz Maria Thea Rane Dela; Motoyama Eri; Ahmed Nabil; ...
第56回日本結合組織学会学術大会/2024-06-15--2024-06-16 - Fibrillin-1 G234D mutation links mouse skin tightness to elastic fiber defects and collagen cross-linking
Hossain ASM Sakhawat; Cruz Maria Thea Rane Dela; Kimura...
第56回日本結合組織学会学術大会/2024-06-15--2024-06-16 - Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
第56回日本結合組織学会学術大会/2024-06-15--2024-06-16 - Investigation of mechanosensing mechanisms in aortic dissection caused by a missense variant in the fibrillin-1
本山 絵理; 木村 健一; Maria Thea Rane Dela Cruz Clarin; 浅野 恵一...
第56回日本結合組織学会学術大会/2024-06-15--2024-06-16 - Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
Kimura Kenichi; Motoyama Eri; Kanki Sachiko; Asano Ke...
International Vascular Biology Meeting 2024/2024-07-02--2024-07-02 - Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
第7回日本循環器学会 基礎研究フォーラム(BCVR)/2023-12-09--2023-12-10 - A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes Tight Skin Phenotype
ASM Sakhawat Hossain; Maria Thea Rane Dela Cruz; Koichi...
第7回エラスチン・関連分子研究会学術集会/2023-11-23--2023-11-24 - Investigation of the molecular pathogenesis of aortic dissection in Fibrillin-1 mutant mice by synchrotron imaging and transcriptomics analysis
Sheikh Md Al Amin; Kimura Kenichi; Motoyama Eri; Delee...
the annual Tsukuba Global Science Week (TGSW) 2023/2023-09-27--2023-09-28 - A Novel Mutation in the Hybrid1 Domain of the Fibrillin 1 Gene Causes an Abnormal Skin Phenotype
ASM Sakhawat Hossain; Yuki Taga; Maria Thea Rane Dela ...
Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB, HCS, and ASIP/2023-10-23--2023-10-26
- Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection.
- Teaching
2023 -- (current) Research Presentation and Discussion University of Tsukuba 2023 -- (current) Topics in Vascular Biology University of Tsukuba - Professional activities
2023-06 -- 2024-06 Jananese Society for Matirx Biology and Medicine 第56回日本結合組織学会学術大会 大会組織委員(庶務) - University Management
2023 -- 2023 仕様策定委員会 仕様策定委員
(Last updated: 2024-12-17)