OISHI Motoi
- Affiliation
- Institute of Pure and Applied Sciences
- Official title
- Associate Professor
- URL
- Research projects
ナノ粒子の界面設計に基づいたDNAウォーカーによる感染症のその場診断法の開発 2020 -- 2022 大石 基 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 18,070,000Yen DNAクリック連鎖反応に最適なナノ界面の構築によるアルツハイマーの客観的早期診断 2015 -- 2017 大石 基 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,940,000Yen 刺激応答性ポリサイラミン/ポリエチレングリコールブロック共重合体によるインテリジェントセンサーおよび薬物キャリアの創製 2006-03 -- (current) 熊谷科学技術振興財団/国内共同研究 1,000,000Yen siRNAのピンポイントデリバリーを可能とする高分子ナノ組織体の創製 2006-04 -- (current) 細胞科学研究財団/国内共同研究 3,000,000Yen 中性子捕捉療法を可能とする高分子ボロン会合体の創製 2007-10 -- (current) 公益信託三菱化学/国内共同研究 1,000,000Yen ピンポイント中性子捕捉療法を目指したPEG化ホウ素ナノゲル粒子によるDDS 2007-12 -- (current) 財団法人東京生化学研究会/国内共同研究 1,500,000Yen 医工学連携によるガンのピンポイント診断・治療を目指したナノデバイスの創製 2009-12 -- (current) 財団法人国際科学技術財団/国内共同研究 1,000,000Yen ガンのピンポイントイメージング・治療を可能とする金コロイド内包型PEG化ナノゲル粒子の創製 2009-04 -- (current) 財団法人宇部興産学術振興財団/国内共同研究 1,000,000Yen １９Ｆ－ＮＭＲタグを有する磁性ナノ粒子による多次元化遺伝子診断システムの開発 2012 -- 2014 Japan Society of for the Promotion of Science/基盤研究(C) 3,900,000Yen 体内での核酸の送達・可視化・定量を目指した金ナノ粒子内包型デバイスの設計と創製 2010 -- 2011 Japan Society of for the Promotion of Science/若手研究(B) 4,160,000Yen more... - Degree
2002-3 博士（材料科学） 北陸先端科学技術大学院大学 - Honors & Awards
2008-05-29 高分子研究奨励賞 - Articles
- Latent Toehold-Mediated DNA Circuits Based on a Bulge-Loop Structure for Leakage Reduction and Its Application to Signal-Amplifying DNA Logic Gates
Taku Sugawara; Oishi Motoi
ACS Applied Materials & Interfaces/16(13)/pp.15907-15915, 2024-3 - Long-Term Cryopreservation of Ready-to-Use DNA-Modified Gold Nanoparticle Derivatives: Effect of Preservation Temperature on Their DNA Dissociation and Functional Stability
Juji Shotaro; Oishi Motoi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN/95(3)/pp.410-412, 2022-03 - Acceleration of DNA Hybridization Chain Reactions on 3D Nanointerfaces of Magnetic Particles and Their Direct Application in the Enzyme-Free Amplified Detection of microRNA
Oishi Motoi; Juji Shotaro
ACS APPLIED MATERIALS & INTERFACES/13(30)/pp.35533-35544, 2021-08 - Simple Single-Legged DNA Walkers at Diffusion-Limited Nanointerfaces of Gold Nanoparticles Driven by a DNA Circuit Mechanism
Oishi Motoi; Saito Kosuke
ACS Nano/14(3)/pp.3477-3489, 2020-2 - Dynamically Programmed Switchable DNA Hydrogels Based on a DNA Circuit Mechanism
Oishi Motoi; Nakatani Kazuki
Small (Weinheim an der Bergstrasse, Germany)/15(15), 2019-03 - Comparative Study of DNA Circuit System-Based Proportional and Exponential Amplification Strategies for Enzyme-Free and Rapid Detection of miRNA at Room Temperature
Oishi Motoi
ACS OMEGA/3(3)/pp.3321-3329, 2018-03 - An Efficient Particle-Based DNA Circuit System: Catalytic Disassembly of DNA/PEG-Modified Gold Nanoparticle-Magnetic Bead Composites for Colorimetric Detection of miRNA
Oishi Motoi; Sugiyama Satomi
Small/12(37)/pp.5153-5158, 2016-07 - Synthesis, characterization, and biomedical applications of core-shell-type stimuli-responsive nanogels - Nanogel composed of poly[2-(N,N-diethylamino)ethyl methacrylate] core and PEG tethered chains
Oishi Motoi; Nagasaki Yukio
REACTIVE & FUNCTIONAL POLYMERS/67(11)/pp.1311-1329, 2007-11 - Enzyme-Free and Isothermal Detection of microRNA Based on Click-Chemical Ligation-Assisted Hybridization Coupled with Hybridization Chain Reaction Signal Amplification
Oishi Motoi
Analytical and Bioanalytical Chemistry/407(14)/pp.4165-4172, 2015-05 - Kinetic study of DNA hybridization on DNA-modified gold nanoparticles with engineered nano-interfaces
Takashima Akari; Oishi Motoi
RSC ADVANCES/5(93)/pp.76014-76018, 2015 - Ultrasensitive Detection of DNA and RNA Based on Enzyme-Free Click Chemical Ligation Chain Reaction on Dispersed Gold Nanoparticles
Kato Daiki; Oishi Motoi
ACS NANO/8(10)/pp.9988-9997, 2014-10 - Radiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticles
Yasui Hironobu; Takeuchi Ryo; Nagane Masaki; Meike Shuns...
Cancer Letter/347(1)/pp.151-158, 2014 - Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation
Oishi Motoi; Nakao Shingo; Kato Daiki
CHEMICAL COMMUNICATIONS/50(8)/pp.991-993, 2014-01 - Rational Design of a Fluorescence-Amplified Aptasensor Based on Enzyme-Assisted Target Recycling Strategy
Nakao Shingo; Oishi Motoi
Chemistry Letters/42(10)/pp.1122-1124, 2013-10 - Pharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer
Sumitani Shogo; Oishi Motoi; Yaguchi Tatsuya; Murotani H...
BIOMATERIALS/33(13)/pp.3568-3577, 2012-05 - Dependence of the swelling behavior of a pH-responsive PEG-modified nanogel on the cross-link density
Tamura Goshu; Shinohara Yuya; Tamura Atsushi; Sanada Yus...
POLYMER JOURNAL/44(3)/pp.240-244, 2012-03 - Pharmacokinetics of Core-Polymerized, Boron-Conjugated Micelles Designed for Boron Neutron Capture Therapy for Cancer
Shogo Sumitani; Motoi Oishi; Tatsuya Yaguchi; Hiroki Mur...
Biomaterials/33/p.3568-3577, 2012-01 - Carborane confined nanoparticles for boron neutron capture therapy: Improved stability, blood circulation time and tumor accumulation
Sumitani Shogo; Oishi Motoi; Nagasaki Yukio
REACTIVE & FUNCTIONAL POLYMERS/71(7)/pp.684-693, 2011-07 - Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid
Hatakeyama Hiroto; Akita Hidetaka; Ito Erika; Hayashi Ya...
BIOMATERIALS/32(18)/pp.4306-4316, 2011-06 - Carborane Confined Nanoparticles for Boron Neutron Capture Therapy: Improved Stability, Blood Circulation Time and Tumor Accumulation
Shogo Sumitani; Motoi Oishi; and Yukio Nagasaki
Reactive & Functional Polymers/71/p.684-693, 2011-01 - Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: Enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core
Tamura Atsushi; Oishi Motoi; Nagasaki Yukio
JOURNAL OF CONTROLLED RELEASE/146(3)/pp.378-387, 2010-09 - Nanodevices in pinpoint cancer diagnostic and therapy : current status and future prospects
大石 基
バイオマテリアル : 生体材料 : Journal of Japanese Society for Biomaterials/28(3)/pp.163-164, 2010-07 - Stimuli-responsive smart nanogels for cancer diagnostics and therapy
Oishi Motoi; Nagasaki Yukio
NANOMEDICINE/5(3)/pp.451-468, 2010-04 - Large payloads of gold nanoparticles into the polyamine network core of stimuli-responsive PEGylated nanogels for selective and noninvasive cancer photothermal therapy
Nakamura Takahito; Tamura Atsushi; Murotani Hiroki; Oishi...
NANOSCALE/2(5)/pp.739-746, 2010-01 - Preparation and Molecular Recognition of SERS Probe Based on Gold Nanoparticles Constructed from PEG-Oligoamine Copolymer Possessing a Coumarin Group between PEG and Oligoamine
Furusho Hitoshi; Oishi Motoi; Kishi Tetsuo; Yasumori Ats...
CHEMISTRY LETTERS/39(1)/pp.52-53, 2010-01 - more...
- Latent Toehold-Mediated DNA Circuits Based on a Bulge-Loop Structure for Leakage Reduction and Its Application to Signal-Amplifying DNA Logic Gates
- Books
- 光学活性ケイ素化合物の重合による光学活性および立体規則性ポリシロキサンの合成
大石 基; 川上 雄資
高分子加工, 2000-01 - RNAi法とアンチセンス法—RNAの科学と応用(3-5, アンチセンス法による遺伝子治療—ナノ粒子による遺伝子治療)
大石 基; 長崎 幸夫; 片岡 一則
講談社, 2005-01 - Polymeric Drug Delivery Systems "Functional PEG for drug delivery Chapter 2"
Motoi Oishi; Yukio Nagasaki; and Kazunori Kataoka
Taylor & Francis Group, 2005-01 - 「医療ゲルの最新技術と開発—バイオミメティックゲルの応用」応用編】第６章 ナノゲルによるピンポイント治療・診断システムへの展開
大石 基; 長崎 幸夫
シーエムシー出版, 2008-01 - “Block Copolymer Synthesis for Nanoscale Drug and Gene Delivery” Chapter 2 in the book entitled “Nanotechnology in Drug Delivery”
Moyoi Oishi anf Yukio Nagasaki; +大石 基
Springer-Verlag Inc. New York, 2008-01 - PEG-siRNA Conjugate Bearing 27 bp siRNA to Form Novel PEGylated Polyplexes with Improved Stability
Tatsumi Taiga; Oishi Motoi; Kataoka Kazunori; Nagasaki Y...
TRANSACTIONS OF THE MATERIALS RESEARCH SOCIETY OF JAPAN, VOL 33, NO 3/MATERIALS RESEARCH SOCIETY JAPAN-MRS-J/pp.807-810, 2008-01 - Application of Stimuli-Responsive Nanogels for High-Performance Nanoreactor and Nanoreservoir of Gold Nanoparticles
Nakamura Takahito; Oishi Motoi; Nagasaki Yukio
TRANSACTIONS OF THE MATERIALS RESEARCH SOCIETY OF JAPAN, VOL 33, NO 3/MATERIALS RESEARCH SOCIETY JAPAN-MRS-J/pp.799-802, 2008-01
- 光学活性ケイ素化合物の重合による光学活性および立体規則性ポリシロキサンの合成
- Conference, etc.
- Runtime DVFS Control with instrumented code in Power-scalable Cluster System
Tatsumi Taiga; Oishi Motoi; Kataoka Kazunori; Nagasaki Y...
Joint Symposium of the Materials-Research-Society-of-Japan - Application of Stimuli-Responsive Nanogels for High-Performance Nanoreactor and Nanoreservoir of Gold Nanoparticles
Nakamura Takahito; Oishi Motoi; Nagasaki Yukio
Joint Symposium of the Materials-Research-Society-of-Japan - POLY 549-pH-Responsive PEGylated nanogels as smart nanodevice for cancer diagnosis and therapy
Oishi Motoi; Nagasaki Yukio
236th National Meeting of the American-Chemical-Society/2008-08 - Development of Efficient siRNA Delivery System to Tumor Cells by Combining Octaarginine, GALA and Enzymatically-Cleavable PEG-Lipid
Sakurai Yu; Hatakeyama Hiroto; Akita Hidetaka; Oishi Mot...
12th Annual Meeting of the American Society of Gene Therapy/2009-05
- Runtime DVFS Control with instrumented code in Power-scalable Cluster System
- Teaching
2024-04 -- 2024-08 Research in Chemistry and Engineering of Materials and BiomaterialsIVA University of Tsukuba. 2024-10 -- 2025-02 Research in Chemistry and Engineering of Materials and Biomaterials VA University of Tsukuba. 2024-04 -- 2024-08 Research in Chemistry and Engineering of Materials and Biomaterials IIIB University of Tsukuba. 2024-04 -- 2024-08 Research in Chemistry and Engineering of Materials and BiomaterialsVA University of Tsukuba. 2024-04 -- 2024-08 Research in Chemistry and Engineering of Materials and Biomaterials IVB University of Tsukuba. 2024-04 -- 2024-08 Research in Chemistry and Engineering of Materials and Biomaterials VB University of Tsukuba. 2024-10 -- 2025-02 Research in Chemistry and Engineering of Materials and BiomaterialsVA University of Tsukuba. 2024-10 -- 2025-02 Research in Chemistry and Engineering of Materials and BiomaterialsIVA University of Tsukuba. 2024-10 -- 2025-02 Research in Chemistry and Engineering of Materials and Biomaterials IIIA University of Tsukuba. 2024-10 -- 2025-02 Research in Chemistry and Engineering of Materials and Biomaterials VA University of Tsukuba. more...
(Last updated: 2024-09-18)