ISHIDA Junji
- Affiliation
- Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
- Official title
- Assistant Professor
- Sex
- Male
- KAKEN ID
- 30323257
- Research fields
Applied biochemistry Laboratory animal science - Research keywords
Blood Pressure Reguration Metabolic Regulation Transcriptional Regulation Intracellular Signal Transduction Transgenic Mice Knockout Mice - Research projects
遺伝子-生理情報の定量解析から紐解く心腎連関の病態形成ネットワーク 2021 -- 2023 石田 純治 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,160,000Yen アルギニンメチル化が担う胎児期の血管形成メカニズムの解明 2017 -- 2019 石田 純治 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 5,070,000Yen 受容体間相互作用を介した血管平滑筋APJ受容体による血管狭窄メカニズムの解明 2014 -- 2016 石田 純治 Japan Society for the Promotion of Science/基盤研究(C) 5,070,000Yen 周産期心筋症モデルマウスの確立と発症メカニズムの解明 2011 -- 2013 石田純治 Japan Society of for the Promotion of Science/基盤研究(B) 15,860,000Yen 妊娠恒常性における胎盤の機能ネットワークに関する研究 2009 -- 2010 石田純治 日本学術振興会/若手研究(B) 3,500,000Yen 新規エネルギー代謝制御系・APJ受容体シグナルの生理機能解析 2007 -- 2008 石田純治 Japan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research 3,790,000Yen 心血管系疾患におけるAPV受容体の作用点に関する研究 2004 -- 2005 石田純治 Japan Society of for the Promotion of Science/若手研究(B) 3,700,000Yen 心血管系疾患におけるAPV受容体の生理機能に関する研究 2002 -- 2003 石田純治 Japan Society of for the Promotion of Science/若手研究(B) 3,900,000Yen 脳レニン・アンギオテンシン系亢進による高血圧マウスの作製と解析 1998 -- 2000 石田純治 Japan Society of for the Promotion of Science/特別研究員奨励費 900,000Yen - Career history
2010-05 -- (current) University of Tsukuba講師 2007-04 -- 2010-05 University of Tsukuba研究員 1999 -- (current) University of TsukubaResearch Associate 1999 -- 2000 University of TsukubaResearch fellow of Institute 2000 -- 2003 University of TsukubaResearch Assistant 2003 -- (current) University of TsukubaLecture - Academic background
1990-04 -- 1994-03 University of Tsukuba Second Cluster of College 生物学類人間生物学コース -- 1999 University of Tsukuba Graduate School, Division of Agriculture Applied Biochemistry - Degree
M.A. University of Tsukuba Ph.D. University of Tsukuba - Academic societies
1998 -- (current) The Japanese Biochemical Society 2001 -- (current) The Molecular Biology Society of Japan 2002 -- (current) The Japanese Society of Hypertension 2005 -- (current) The Society of Cardiovascular Endocrinology and Metabolism 2005 -- (current) Japanese society for Circulation Research 2009 -- (current) The Japan Society for the Study of Hypertension in Pregnancy 2014 -- (current) Japanese Society of Molecular Medicine 2016 -- (current) Society of Hypertension Related Disease Model Research 2002 -- (current) Molecular Cardiovascular Metabolic Conference - Honors & Awards
2010-04 ポスター・アワード 2008-09 ポスター・アワード 2007-02 日本心脈管作動物質学会研究奨励賞 2005-11 Young Investigator's Award 2005-10 Young Investigator's Award最優秀賞 2005-06 Young Investigator Travel Grant 2000 International Society of Hypertension Young Investigator's Travel Award - Articles
- ANALYSIS OF SHORT-TERM CARDIOVASCULAR AND RENAL DISORDERS IN MICE WITH CARDIO-RENAL DAMAGES
Noguchi Kazuyuki; Ishida Junji; Muromachi Naoto; Akiya...
JOURNAL OF HYPERTENSION/41(1)/pp.E363-E363, 2023-01 - Cardiorenal damages in mice at early phase after intervention induced by angiotensin II, nephrectomy, and salt intake
Muromachi Naoto; Ishida Junji; Noguchi Kazuyuki; Akiya...
EXPERIMENTAL ANIMALS/73(1)/pp.11-19, 2023-07-18 - Apelin expression is downregulated in T cells in a murine model of chronic colitis
Yamada Daiki; Kojima Yudai; Hosoya Akinori; Suzuki Ma...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/647/pp.72-79, 2023-03-05 - Apelin expression is downregulated in T cells in a murine model of chronic colitis
Yamada Daiki; Kojima Yudai; Hosoya Akinori; Suzuki Masah...
Biochemical and biophysical research communications/647/pp.72-79, 2023-03-05 - Apelin expression is downregulated in T cells in a murine model of chronic colitis
Yamada Daiki; Kojima Yudai; Hosoya Akinori; Suzuki Masah...
Biochemical and biophysical research communications/647/pp.72-79, 2023-03-05 - Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide
Tokudome Takeshi; Otani Kentaro; Mao Yuanjie; Jensen ...
HYPERTENSION/79(7)/pp.1409-1422, 2022-07 - Disruption of entire locus leads to embryonic lethality by diminished gene expression and enhanced p53 pathway
Dinh Tra Thi Huong; Iseki Hiroyoshi; Mizuno Seiya; Iijima...
eLife, 2021-05 - Disruption of entire locus leads to embryonic lethality by diminished gene expression and enhanced p53 pathway
Dinh Tra Thi Huong; Iseki Hiroyoshi; Mizuno Seiya; Iij...
eLife/10, 2021-05 - Loss of PRMT1 in the central nervous system (CNS) induces reactive astrocytes and microglia during postnatal brain development
Hashimoto Misuzu; Kumabe Ayako; Kim Jun-Dal; Murata K...
JOURNAL OF NEUROCHEMISTRY/Epub/pp.834-847, 2021-03 - Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs
Matsuda Shuichi; Kim Jun-Dal; Sugiyama Fumihiro; Matsu...
International journal of molecular sciences/21(18), 2020-09 - Histamine receptor agonist alleviates severe cardiorenal damages by eliciting anti-inflammatory programming
Noguchi Kazuyuki; Ishida Junji; Kim Jun-Dal; Muromach...
Proceedings of the National Academy of Sciences of the United States of America/117(6)/pp.3150-3156, 2020-02 - Histamine receptor agonist alleviates severe cardiorenal damages by eliciting anti-inflammatory programming
Noguchi Kazuyuki; Ishida Junji; Kim Jun-Dal; Muromachi N...
Proceedings of the National Academy of Sciences of the United States of America/117(6)/pp.3150-3156, 2020-01 - Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives
Freyer Laina; Hsu Chih-Wei; Nowotschin Sonja; Pauli Andr...
Cell reports/20(9)/pp.2116-2130, 2017-08 - Histamine receptor agonist alleviates severe cardiorenal damages by eliciting anti-inflammatory programming
Noguchi Kazuyuki; Ishida Junji; Kim Jun-Dal; Muromachi N...
Proceedings of the National Academy of Sciences of the United States of America/117(6)/pp.3150-3156, 2020-01 - Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart
Otani Kentaro; Tokudome Takeshi; Kamiya Chizuko A; Mao...
Circulation/141(7)/pp.571-588, 2019-10 - Cooperative action of APJ and α1A-adrenergic receptor in vascular smooth muscle cells induces vasoconstriction
Nagano Katsumasa; Kwon Chulwon; Ishida Junji; Hashimoto ...
Journal of biochemistry/166(5)/pp.383-392, 2019-09 - PRMT1 Deficiency in Mouse Juvenile Heart Induces Dilated Cardiomyopathy and Reveals Cryptic Alternative Splicing Products
Murata Kazuya; Lu Weizhe; Hashimoto Misuzu; Ono Natsumi; ...
iScience/8/pp.200-213, 2018-10 - Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells
Hashimoto Tatsuo; Kihara Minoru; Ishida Junji; Imai Nozo...
Arteriosclerosis, thrombosis, and vascular biology/26(6)/pp.1267-1272, 2006-06 - Pathophysiology of placentation abnormalities in pregnancy-induced hypertension
Furuya Mitsuko; Ishida Junji; Aoki Ichiro; Fukamizu Akiy...
Vascular health and risk management/4(6)/pp.1301-1313, 2008-04 - Embryonic Intra-Aortic Clusters Undergo Myeloid Differentiation Mediated by Mesonephros-Derived CSF1 in Mouse.
Sasaki T; Tanaka Y; Kulkeaw K; Yumine-Takai A; Tan KS; Ni...
Stem Cell Rev./12(5)/pp.530-542, 2016-06 - Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System
Hashimoto Misuzu; Murata Kazuya; Ishida Junji; Kanou Aki...
J. Biol. Chem./291(5)/pp.2237-2245, 2016-01 - Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells
Kato Hideki; Ishida Junji; Nagano Katsumasa; Honjo Kaori...
LABORATORY INVESTIGATION/88(7)/pp.731-739, 2008-07 - A Combination of HNF-4 and Foxo1 Is Required for Reciprocal Transcriptional Regulation of Glucokinase and Glucose-6-phosphatase Genes in Response to Fasting and Feeding
Hirota Keiko; Sakamaki Jun-ichi; Ishida Junji; Shimamoto ...
JOURNAL OF BIOLOGICAL CHEMISTRY/283(47)/pp.32432-32441, 2008-11 - Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene
Shimamoto Y; Ishida J; Yamagata K; Saito T; Kato H; Matsu...
JOURNAL OF BIOLOGICAL CHEMISTRY/279(9)/pp.7770-7776, 2004-02 - Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression
Ieda M; Fukuda K; Hisaka Y; Kimura K; Kawaguchi H; Fujita...
JOURNAL OF CLINICAL INVESTIGATION/113(6)/pp.876-884, 2004-03 - more...
- ANALYSIS OF SHORT-TERM CARDIOVASCULAR AND RENAL DISORDERS IN MICE WITH CARDIO-RENAL DAMAGES
- Conference, etc.
- humanized PRMT1 mice (huMice)に対する高血圧負荷
丸橋春介; 姚遠; 本村香織; 野口和之; 加香 孝一郎; 石田純治; 深水 昭吉
第97回日本生化学会大会/2024-11-6--2024-11-8 - 心腎関連モデルマウスの初期心腎障害の病理学的解析
室町 直人; 石田 純治; 野口 和之; 深水 昭吉
第96回日本生化学会大会/2023-10-31--2023-11-2 - ANALYSIS OF SHORT-TERM CARDIOVASCULAR AND RENAL DISORDERS IN MICE WITH CARDIO-RENAL DAMAGES
Noguchi Kazuyuki; Ishida Junji; Muromachi Naoto; Akiya...
29th Scientific Meeting of the International Society of Hypertension (ISH)/2022-10-12--2022-10-16 - 心腎連関モデルマウスの初期病態へのヒスタミンH3アゴニストの作用
室町直人; 石田純治; 野口和之; 深水昭吉
2023年度日本生化学会関東支部例会/2023-06-10--2023-06-10 - 心腎障害マウスにおける心血管系短期障害病態の解析
野口 和之; 石田 純治; 室町 直人; 金俊達; 臼井 丈一; 山縣 邦弘; 深水 昭吉
第65回日本腎臓学会学術総会/2022-06-10--2022-06-12 - 心腎連関モデルマウスの初期病態に対するヒスタミンH3アゴニストの検討
室町直人; 石田純治; 野口和之; 深水 昭吉
第95回日本生化学会大会/2022-11-10 - マウス血漿中の遊離メチルアルギニン分析法の確立
丸橋春介; 加香孝一郎; 加藤薫; 室町直人; 石田純治; 深水 昭吉
第95回日本生化学会大会/2022-11-09 - Integrated experimental-theoretical approaches to decipher how H179Y substitution affects the biological functions of PRMT1
Yao Yuan; Jun-Dal Kim; Hiroaki Daitoku; Naoto Muromachi; ...
2022年度日本生化学会関東支部例会/2022-06-18 - 心腎連関モデルマウスの病態初期での心腎機能・障害の解析
室町直人; 石田純治; 野口和之; 深水 昭吉
CVEM2021/2021-12-10--2021-12-10 - Study on the effect of H179Y one-point mutation in murine PRMT1 on biological functions
姚遠; 金俊逹; 大徳浩照; 室町直人; 石田純治; 深水 昭吉
第94回日本生化学会大会/2021-11-04--2021-11-04 - 高血圧妊娠仔FGRの遺伝子発現の特質解析
石田純治; 松田紘奈; 金俊逹; 深水 昭吉
第94回日本生化学会大会/2021-11-04--2021-11-04 - 脂肪組織形成におけるMETTL18を介したヒスチジンメチル化に関する研究
岸川奈那; 金俊逹; 石田純治; 深水 昭吉
第94回日本生化学会大会/2021-11-04--2021-11-04 - 心腎連関モデルマウスの初期心腎機能・障害の解析
室町直人; 石田純治; 野口和之; 深水 昭吉
第94回日本生化学会大会/2021-11-04--2021-11-04 - 二重酵素活性を有するPRMT8の活性変異マウスの作製と機能解析
森遥佳; 金俊達; 石田純治; 深水昭吉
第94回日本生化学会大会/2021-11-3--2021-11-5 - ヒトアンジオテンシノーゲン外来遺伝子のマウスゲノム挿入部位の同定
松田紘奈; 石田純治; 室町直人; 深水 昭吉
第94回日本生化学会大会/2021-11-3--2021-11-5 - 遺伝子発現プロファイリングから探る,心腎連関病態のH3アゴニストによる病態改善メカニズム
笠井郁也; 石田純治; 室町直人; 野口和之; 金俊逹; 深水 昭吉
第94回日本生化学会大会/2021-11-03--2021-11-05 - ヒスタミンH3アゴニストによる心腎連関病態への抗炎症作用メカニズムの解析
野口和之; 石田純治; 金 俊達; 室町直人; 臼井丈一; 山縣 邦弘; 深水昭吉
第64回日本腎臓学会学術総会/2021-06-18--2021-06-18 - H3受容体アゴニストの抗炎症作用を介した心腎病態保護作用の解明
野口和之; 石田純治; 金俊達; 室町直人; 加香孝一郎; 金子修三; 臼井丈一; 山縣邦弘; 深水昭吉
第63回日本腎臓学会学術総会/2020-08-19--2020-08-21 - Cardiac profiling of gene expression in a mouse model of cardio-renal association with the histamine H3 receptor agonist
室町直人; 石田 純治; 野口和之; 金 俊逹; 深水 昭吉
第24回日本心血管内分泌代謝学会学術総会/2021-03-12 - ヒスタミンH3受容体アゴニストの心腎病態での遺伝子発現プロファイリング
室町直人; 金俊達; 石田純治; 野口和之; 深水昭吉
第93回日本生化学会大会/2020-09-14--2020-09-16 - 高血圧誘導性心腎病態モデルマウス(ANSマウス)におけるヒスタミンの分析
加香孝一郎; 石田純治; 金俊達; 室町直人; 深水昭吉
第22回 日本ヒスタミン学会/2020-02-02--2020-02-03 - 高血圧誘導性心不全モデルマウス(ANSマウス)におけるヒスタミンの定量
加香 孝一郎; 石田 純治; 金 俊達; 室町 直人; 深水 昭吉
第23回 活性アミンに関するワークショップ/2019-08-24--2019-08-24 - Histamine H3 receptor agonist has a therapeutic potential for cardio-renal damages.
野口和之; 石田純治; 山縣 邦弘; 深水昭吉
第42回日本高血圧学会総会/2019-10-25--2019-10-27 - 外来性遺伝子導入によるAG遺伝子欠損マウスの機能回復
石田純治; 杉山文博; 谷本啓司; 村上和雄; 八神健一; 深水昭吉
日本分子生物学会年会/1996-08--1996-08 - 心腎連関病態モデルマウスの確立と解析
野口和之; 石田純治; 室町直人; 金 俊達; 加香孝一郎; 山縣 邦弘
第62回日本腎臓学会学術総会/2019-06-21--2019-06-23 - more...
- humanized PRMT1 mice (huMice)に対する高血圧負荷
- Teaching
2024-10 -- 2024-11 Fundamental Chemistry Laboratory University of Tsukuba. 2024-04 -- 2024-08 Seminar in Applied Biochemistry IIF(Spring) University of Tsukuba. 2024-04 -- 2024-08 Research in Applied Biochemistry IIF(Spring) University of Tsukuba. 2024-04 -- 2024-08 Seminar in Life and Agricultural Sciences University of Tsukuba. 2024-10 -- 2025-02 Seminar in Life and Agricultural Sciences University of Tsukuba. 2024-10 -- 2025-02 Dissertation in Animal Life Science III University of Tsukuba. 2024-04 -- 2024-08 Dissertation in Animal Life Science III University of Tsukuba. 2024-10 -- 2024-11 Fundamental Chemistry Laboratory University of Tsukuba. 2024-10 -- 2025-02 Research in Applied Biochemistry IF University of Tsukuba. 2024-04 -- 2024-08 Research in Applied Biochemistry IIS University of Tsukuba. more... - Professional activities
2023-04 -- 2024-03 筑波大学 動物実験委員会
(Last updated: 2024-09-06)