USUI Takeo
- Articles
- 34 Synthesis and Biological Evaluation of 6,6-Spiroketal Natural Products
清水 猛; 佐藤 智陽; 藤倉 真人; 村越 克典; 臼井 健郎; 川谷 誠; 長田 裕之; 袖岡 幹子
天然有機化合物討論会講演要旨集/0(49)/pp.199-204, 2007-08 - Actin- and microtubule-targeting bioprobes: Their binding sites and inhibitory mechanisms
Usui Takeo
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY/71(2:::Sp. Iss. 283)/pp.300-308, 2007-02 - Actin- and microtubules-targeting bioprobes; its binding sites and inhibitory mechanisms.
Usui T.
Biosci. Biotechnol. Biochem./71/p.300-308, 2007-01 - Antiproliferating activity of the mitotic inhibitor pironetin against vindesine- and paclitaxel-resistant human small cell lung cancer H69 cells.
Yoshida; M.; Matsui; Y.; Ikarashi; Y.; Usui; T.; Osada; H.; and Wa...
Anticancer Res./27/p.729-736, 2007-01 - Brasilicardin A, a natural immunosuppressant, targets amino acid transport system L
Usui Takeo; Nagumo Yoko; Watanabe Ai; Kubota Takaaki; Kom...
CHEMISTRY & BIOLOGY/13(11)/pp.1153-1160, 2006-11 - 6 Development of RK-682 Enamide Derivatives as Protein Phosphatase Inhibitors
平井 剛; 尾谷 優子; 土屋 綾子; 闐闐 孝介; 臼井 健郎; 長田 裕之; 袖岡 幹子
天然有機化合物討論会講演要旨集/0(48)/pp.31-36, 2006-09 - Phenothiazine and carbazole-related compounds inhibit mitotic kinesin Eg5 and trigger apoptosis in transformed culture cells.
Okumura; H.; Nakazawa; J.; Tsuganezawa; K.; Usui; T.; Osada; H.; Ma...
Toxicol. Lett./166/p.44-52, 2006-01 - Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin.
Uchimura; S.; Oguchi; Y.; Katsuki; M.; Usui; T.; Osada; H.; Nikawa; ...
EMBO J./25/p.5932-5941, 2006-01 - Iejimalides show anti-osteoclast activity via V-ATPase inhibition.
Kazami; S.; Muroi; M.; Kawatani; M.; Kubota; T.; Usui; T.; Kobayash...
Biosci. Biotechnol. Biochem./70/p.1364-1370, 2006-01 - 天然由来のバイオプローブを用いたケミカルジェネティクスとケミカルゲノミクス (特集 ケミカルゲノミクスの誕生)
叶 直樹; 清水 史郎; 臼井 健郎
Protein, nucleic acid and enzyme/50(9)/pp.1037-1042, 2005-08 - 3P177 How are the helix 12 in α- and β-tubulin subunit involved in kinesin motility?
内村 誠一; 香月 美穂; 川口 友彰; 臼井 健郎; 長田 裕之; 武藤 悦子
Biophysics/44(1)/p.S234, 2004-11 - Amphidinolide H, a potent cytotoxic macrolide, covalently binds on actin subdomain 4 and stabilizes actin filament.
Usui T.; Kazami S.; Dohmae N.; Mashimo Y.; Kondo H.; Tsud...
Chem. Biol./11/p.1269-1277, 2004-01 - The anti-cancer natural product pironetin selectively targets Lys352 of alpha-tubulin.
Usui; T.; Watanabe; H.; Nakayama; H.; Tada; Y.; Kanoh; N.; Kondoh; M...
Chem. Biol./11/p.799-806, 2004-01 - Nordihydroguaiaretic acid, of a new family of microtubule-stabilizing agents, shows effects differentiated from paclitaxel.
Nakamura; M.; Nakazawa; J.; Usui; T.; Osada; H.; Kono; Y.; and Tak...
Biosci. Biotechnol. Biochem./67/p.151-157, 2003-01 - A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5.
Nakazawa; J.; Yajima; J.; Usui; T.; Ueki; M.; Takatsuki; A.; Imoto; ...
Chem. Biol./10/p.131-137, 2003-01 - 4-isoavenaciolide covalently binds and inhibits VHR, a dual-specificity phosphatase.
Ueda; K.; Usui; T.; Nakayama; H.; Ueki; M.; Takio; K.; Ubukata; M.; a...
FEBS Lett./525/p.48-52, 2002-01 - Bitungolides A-F, new polyketides from the Indonesian sponge Theonella cf. swinhoei.
Sirirath; S.; Tanaka; J.; Ohtani; II; Ichiba; T.; Rachmat; R.; Ueda...
J. Nat. Prod./65/p.1820-1823, 2002-01 - Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A.
Miyamoto; Y.; Machida; K.; Mizunuma; M.; Emoto; Y.; Sato; N.; Miyah...
J. Biol. Chem./277/p.28810-28814, 2002-01 - Chemical modification of reveromycin A and its biological activities.
Shimizu; T.; Usui; T.; Machida; K.; Furuya; K.; Osada; H.; and Nak...
Bioorg. Med. Chem. Lett./12/p.3363-3366, 2002-01 - 微小管に作用するアルカロイド化合物新しい微小管作用薬開発のリード化合物としての可能性
臼井 健郎; 長田 裕之
化学と生物/39(2)/pp.79-81, 2001-02 - Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp.
Sano; T.; Usui; T.; Ueda; K.; Osada; H.; and Kaya; K.; +臼井 健郎
J. Nat. Prod./64/p.1052-1055, 2001-01 - Design and synthesis of a dimeric derivative of RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase: implications for the molecular mechanism of the inhibition.
Usui; T.; Kojima; S.; Kidokoro; S.; Ueda; K.; Osada; H.; and Sodeo...
Chem. Biol./8/p.1209-1220, 2001-01 - Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition.
Sodeoka; M.; Sampe; R.; Kojima; S.; Baba; Y.; Usui; T.; Ueda; K.; and...
J. Med. Chem./44/p.3216-3222, 2001-01 - Studies on inhibitory mechanism of microtubule inhibitors.
Usui; T.; Nakazawa; J.; and Osada; H.; +臼井 健郎
RIKEN Review/41/p.92-93, 2001-01 - Microtubule proteins and chemical inhibitors
長田 裕之; 中澤 順子; 臼井 健郎
Bioscience & industry/58(11)/pp.35-38, 2000-11 - more...
- 34 Synthesis and Biological Evaluation of 6,6-Spiroketal Natural Products