OHNEDA Osamu
- Affiliation
- Institute of Medicine
- Official title
- Professor
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- Fax
- 029-853-2938
- Research fields
Cell biology Developmental biology - Research projects
間葉系幹細胞由来細胞外小胞を用いたエピジェネティック制御機構の解明 2024 -- 2026 Ohneda Osamu Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,680,000Yen 間葉系幹細胞由来機能性細胞外小胞体の臨床応用に向けた研究開発 2021 -- 2023 大根田 修 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,160,000Yen 2型糖尿病由来間葉系幹細胞の単離およびその機能解析 2016 -- 2018 大根田 修 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,810,000Yen 2型糖尿病由来間葉系幹細胞の単離およびその機能解析 2016 -- 2018 大根田修 JSPS/基盤研究(C) 4,810,000Yen ヒト初代培養乳癌幹細胞における浸潤・転移能獲得の分子機能解明 2013 -- 2015 坂東裕子 JSPS/Kiban Kenkyu (c) 4,940,000Yen 機能性間葉系幹細胞の単離とその機能解析 2012 -- 2014 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 5,590,000Yen 虚血性疾患治療に効果的な血管内皮前駆細胞の機能解析 2008 -- 2010 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 4,550,000Yen "新規ケモカイン""WECHE""の造血・発生における機能解析" 2002 -- (current) 大根田修 Japan Society of for the Promotion of Science/基盤研究(C) 6,000,000Yen 脳腫瘍に対する血管新生抑制療法の展開:新規治療法と抵抗性の克服 2009 -- 2011 高野晋吾 JSPS/Kiban Kenkyu B 17,550,000Yen - Academic background
-- 1987 Tohoku University Faculty of Medicine -- 1993 Tohoku University Graduate School, Division of Medicine 内科学 - Degree
Doctor of Medicine Tohoku University - Academic societies
-- (current) The Japanese Cancer Association -- (current) THE JAPANESE SOCIETY OF HEMATOLOGY -- (current) THE JAPANESE BIOCHEMICAL SOCIETY -- (current) The Molecular Biology Society of Japan -- (current) THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE -- (current) THE JAPANESE CIRCULATION SOCIETY -- (current) American Society of Hematology - Honors & Awards
2000 日本血液学会奨励賞 - Articles
- Antibacterial effects of human mesenchymal stem cells and their derivatives: a systematic review
Adeline Castro Ramos; Yovian Widjaja Lomanto Markus; Ca...
Frontiers in microbiology/(15), 2024-09 - Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway
Vuong Cat-Khanh; Fukushige Mizuho; Ngo Nhat-Hoang; Yam...
Stem cells and development/33(11-12)/pp.262-275, 2024-06-01 - Extracellular vesicles derived from SARS-CoV-2 M-protein-induced triple negative breast cancer cells promoted the ability of tissue stem cells supporting cancer progression
Nguyen Hoai-Nga Thi; Vuong Cat-Khanh; Fukushige Mizuho...
FRONTIERS IN ONCOLOGY/14, 2024-03-07 - Impairment of HIF-2α Expression Induced the Compensatory Overexpression of the HIF-1α/SDF-1 Axis to Promote Wound Healing
Yamashita Toshiharu; Vuong Cat-Khanh; Ngo Nhat-Hoang; ...
STEM CELLS AND DEVELOPMENT/32(19-20)/pp.592-605, 2023-10-01 - Uremic Toxins Affect the Imbalance of Redox State and Overexpression of Prolyl Hydroxylase 2 in Human Adipose Tissue-Derived Mesenchymal Stem Cells Involved in Wound Healing
Vuong Cat Khanh; Ohneda Kinuko; Kato Toshiki; Yamashita ...
Stem Cells and Development, 2017-05 - Type 2 Diabetes Mellitus Promotes the Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells into Cancer-Associated Fibroblasts, Induced by Breast Cancer Cells
Chang Yun-Hsuan; Ngo Nhat-Hoang; Khanh Vuong Cat; Yamashi...
STEM CELLS AND DEVELOPMENT/31(21-22)/pp.659-671, 2022-07 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Khanh Vuong Cat; Yamashi...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY/10, 2022-08 - Dynamic Changes of Mouse Embryonic Stem Cell-Derived Neural Stem Cells Under In Vitro Prolonged Culture and Hypoxic Conditions
Lukmanto Donny; Khanh Vuong Cat; Shirota Saori; Kato Tos...
Stem Cell and Development, 2019-11 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells.
Nguyen Hoai-Nga Thi; Kawahara Marie; Khanh Vuong Cat; Fuk...
FRONTIERS IN ONCOLOGY, 2022-06 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Vuong Cat Khanh; Ngo Nhat-Hoang; Chang Yun-Hsuan; Yamashi...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022-08 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Nguyen Hoai-Nga Thi; Kawahara Marie; Vuong Cat-Khanh; Fuk...
FRONTIERS IN ONCOLOGY/12, 2022-06 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Vuong Cat-Khanh; Yamashi...
Frontiers in Cell and Developmental Biology, 2022-08 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Vuong Cat-Khanh; Yamashi...
Frontiers in Cell and Developmental Biology, 2022-08 - Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Chang Yun-Hsuan; Vuong Cat-Khanh; Ngo Nhat-Hoang; Yama...
Scientific reports/12(1), 2022-08-08 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Vuong Cat-Khanh; Yamashi...
Frontiers in Cell and Developmental Biology, 2022-08 - Dynamic Changes of Mouse Embryonic Stem Cell-Derived Neural Stem Cells Under In Vitro Prolonged Culture and Hypoxic Conditions
Lukmanto Donny; Shirota Saori; Kato Toshiki; Takasaki Ma...
Stem Cells and Development/28(21)/pp.1434-1450, 2019-11 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Nguyen Hoai-Nga Thi; Kawahara Marie; Vuong Cat-Khanh; Fuk...
Front. Oncol., 2022-06 - Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Chang Yun-Hsuan; Vuong Cat-Khanh; Ngo Nhat-Hoang; Yama...
SCIENTIFIC REPORTS/12(1), 2022-08-08 - Dynamic Changes of Mouse Embryonic Stem Cell-Derived Neural Stem Cells Under In Vitro Prolonged Culture and Hypoxic Conditions
Lukmanto Donny; Khanh Vuong Cat; Shirota Saori; Kato Tos...
Stem Cells and Development/28(21)/pp.1434-1450, 2019-11 - Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Chang Yun-Hsuan; Vuong Cat-Khanh; Ngo Nhat-Hoang; Yama...
Scientific reports/12(1), 2022-08-08 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Vuong Cat-Khanh; Yamashi...
Frontiers in Cell and Developmental Biology, 2022-08 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Nguyen Hoai-Nga Thi; Kawahara Marie; Fukushige Mizuho; Oh...
Frontiers in oncology, 2022-06 - Effect of the COVID-19 pandemic on antibiotic consumption: A systematic review comparing 2019 and 2020 data
Fukushige Mizuho; Ngo Nhat-Hoang; Lukmanto Donny; Fuku...
FRONTIERS IN PUBLIC HEALTH/10, 2022-10 - Transformed extracellular vesicles with high angiogenic ability as therapeutics of distal ischemic tissues
Ngo Nhat-Hoang; Chang Yun-Hsuan; Vuong Cat-Khanh; Yamashi...
Frontiers in Cell and Developmental Biology, 2022-08 - Extracellular vesicles derived from Wharton's Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Chang Yun-Hsuan; Vuong Cat-Khanh; Ngo Nhat-Hoang; Yama...
Scientific reports/12(1), 2022-08-08 - more...
- Antibacterial effects of human mesenchymal stem cells and their derivatives: a systematic review
- Conference, etc.
- Infant-Modified Adipose-Derived Mesenchymal Stem Cells Modulates Microglial Response in a Rodent Stroke Model
Puentes Sandra; Khanh Vuong Cat; Osamu Ohneda; Aiki M...
IEEE 45th Annual International Conference of the Engineering in Medicine and Biology Society (EMBC) 2023/2023-07-24--2023-07-28 - Transformed Extracellular Vesicles with High Angiogenic Ability as Therapeutics of Distal Ischemic Tissues
Ngo Nhat-Hoang; Khanh Vuong Cat; Yamashita Toshiharu; Ohn...
Tsukuba Global Science Week 2022/2022-09-29 - Extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1α signaling pathway
Yun-Hsuan Chang; Vuong Cat Khanh; Toshiharu Yamashita; Os...
Tsukuba Global Science Week 2022/2022-09-30 - SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Nguyen Hoai-Nga Thi; Khanh Vuong Cat; Yamashita Toshihar...
Tsukuba Global Science Week 2022/2022-09-29 - より高い治療効果を持つ機能性血管内皮前駆細胞 (EPC) の作成
佐藤悠樹; Vuong Cat Khanh; Toshiharu Yamashita; Osamu Ohneda
第18回日本再生医療学会総会/2019-03-21--2019-03-23 - 老化による脂肪組織由来間葉系幹細胞の創傷治癒能に対する影響の解析
原彩美; Vuong Cat Khanh; Toshiharu Yamashita; Osamu Ohneda
第18回日本再生医療学会総会/2019-03-21--2019-03-23 - Study the effects of type 2 diabetes mellitus on functions of Wharton jelly's Mesenchymal stem cells for the treatment of diabetic foot ulcer
Sipayung Shinta Masyta; Khanh Vuong Cat; Yamashita Toshi...
The Joint Young Research Meeting in Biomedical Science/2020-01-10--2020-01-11 - Impairment of Sirt1 plays the key role in the dysfunction of mesenchymal stem cells in beige adipogenesis
Vuong Cat Khanh; Yamashita Toshiharu; Ohneda Osamu
The Joint Young Research Meeting in Biomedical Science/2020-01-10--2020-01-11 - Effects of aging on mesenchymal stem cells
VUONG CAT KHANH; Yamashita Toshiharu; Ohneda Osamu
The 1st University of Tsukuba-University of Science Vietnam Joint Symposium 2019/2019-02-23 - Nicotine and SARS-CoV-2 Protein Induce the Malignancy of Lung Cancer Cell. International Student Presentations of Medical and Life Sciences Session.
Lomanto Markus Yovian Widjaja; Nguyen Hoai-Nga Thi; Khanh...
Tsukuba Global Science Week 2022/2022-09-29 - Study the effects of Type 2 diabetes mellitus on beige adipogenesis of Mesenchymal stem cells
Takeuchi Kosuke; Khanh Vuong Cat; Yamashita Toshiharu; Oh...
Tsukuba Science Week 2018/2018-09-20 - Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3 alpha In Vivo
Pan Xiaoqing; Suzuki Norio; Hirano Ikuo; Yamazaki Shun; Y...
52nd Annual Meeting of the American-Society-of-Hematology (ASH)/2010-12-04--2010-12-07 - A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a
Nagano Masumi; Kimura Ken-ichi; Yamashita Toshiharu; Hama...
50th Annual Meeting of the American- Society-of-Hematology/2008-12-6--2008-12-9 - THE ROLE OF CHEMOKINE SDF-1 AND CXCR4 IN GLIOMA ANGIOGENESIS AND INVASIVENESS: INTERACTION BETWEEN GLIOMA AND GLIOMA-DERIVED ENDOTHELIAL CELLS
Takano Shingo; Osuka Satoru; Mashiko Ryota; Ohneda Osamu...
17th International Conference on Brain Tumor Research and Therapy/2008-06-09--2008-06-12 - THE ROLE OF CHEMOKINE SDF-1/CXCR4/CXCR7 FOR GLIOBLASTOMA ANGIOGENESIS AND GLIOBLASTOMA-DERIVED ENDOTHELIAL CELLS
Takano Shingo; Yamashita Toshio; Nagano Masumi; Mashiko ...
3rd Quadrennial Meeting of the World-Federation-of-Neuro-Oncoloyg/6th Meeting of the Asian-Society-for-Neuro-Oncology
- Infant-Modified Adipose-Derived Mesenchymal Stem Cells Modulates Microglial Response in a Rodent Stroke Model
- Teaching
2024-04 -- 2024-08 Special Research in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Humanics IIIb University of Tsukuba. 2024-10 -- 2025-02 Basic Experiments in Human Biology University of Tsukuba. 2024-08 -- 2024-09 Agro-Biomedical Science Laboratory Seminar I University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Human Biology I University of Tsukuba. 2024-10 -- 2025-02 Special Lectures in Humanics IIIb University of Tsukuba. 2024-10 -- 2024-11 Research and Development for Agro-Biomedical Science I University of Tsukuba. 2024-04 -- 2024-08 Special Lectures in Humanics IIIa University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Human Biology II University of Tsukuba. more... - Talks
- 治療効果の高い間葉系幹細胞の単離およびその機能解析.
大根田 修
日本生化学会 関東支部例会/2009-04-01 - ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療と機能解析.
大根田 修
日本生化学会 関東支部例会/2009-04-01 - ヒト間葉系幹細胞を用いたグリオグラストーマの細胞治療に向けた研究開発.
大根田 修
第8回 日本再生医療学会総会/2009-04-01 - 治療効果の高い間葉系幹細胞の単離およびその機能解析.
大根田 修
第8回 日本再生医療学会総会/2009-04-01 - Differential Potential of Endothelial Progenitor Cells to Promote Arteriogenesis and Angiogenesis.
大根田 修
Cardiovascular Research Technologies/2009-04-01 - CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation by HIF-2a.
大根田 修
第73回 日本循環器学会総会・学術集会/2009-04-01 - 赤血球分化における低酸素応答転写因子HIF-2aの機能解析.
大根田 修
第70回 日本血液学会総会/2008-04-01 - 虚血改善効果の高いヒト血管内皮前駆細胞における低酸素応答転写因子の機能解析.
大根田 修
第70回 日本血液学会総会/2008-04-01 - 膠芽腫由来血管内皮細胞の特性から考える血管新生抑制療法.
大根田 修
第67回 日本癌学会学術総会/2008-04-01 - 生体内におけるHIF-3a /IPAS発現部位の同定.
大根田 修
第6回 がんとハイポキシア研究会/2008-04-01 - HIF-3aによる負の転写制御機構解明.
大根田 修
第6回 がんとハイポキシア研究会/2008-04-01 - A Chemokine Receptor CXCR4 Plays a Crucial Role for Repairing Ischemic Tissue through Regulation of HIF-2a.
大根田 修
50th ASH Annual Meeting/2008-04-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第4回 麒麟塾/2008-04-01 - ヒト臍帯血由来間葉系幹細胞の単離と同定.
大根田 修
第7回 日本再生医療学会/2008-04-01 - 治療効果・安全性が高い細胞単離/保存方法の開発
大根田 修
TX テクノロジー・ショーケース イン ツクバ 2008/2008-01-01 - Analyses of functional roles of HIFs in endothelial cells
大根田 修
ERATO シンポジウム/2007-11-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第5回がんとハイポキシア研究会/2007-11-01 - 新規bHLH/PAS転写因子 NEPAS の機能解析
大根田 修
第5回がんとハイポキシア研究会/2007-11-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第69回日本血液学会/2007-10-01 - GATA-1遺伝子変異細胞株(GAK14)を用いたGATA-1N末端の機能解析
大根田 修
第69回日本血液学会/2007-10-01 - HIF-2α in endothelial cells regulates tumor neovascularization through activation of ephrin A1
大根田 修
第66回日本癌学会/2007-10-01 - 虚血改善効果の高いヒト血管内皮前駆細胞の単離および機能解析
大根田 修
第6回日本再生医療学会/2007-03-01 - 新規bHLH/pas転写因子の機能解析
大根田 修
第29回日本分子生物学会/2006-12-01 - 血管内皮前駆細胞を用いたグリオーマに対する血管新生抑制療法
大根田 修
第14回日本血管生物医学会/2006-12-01 - ヒト臍帯血由来間葉系幹細胞の遊走能解析
大根田 修
第11回つくばバイオマテリアル研究会「再生医療とナノメディシン」/2006-11-01 - more...
- 治療効果の高い間葉系幹細胞の単離およびその機能解析.
- Professional activities
-- (current) THE JAPANESE BIOCHEMICAL SOCIETY 評議委員 - University Management
2017-04 -- 2018-03 生命システム医学専攻 運営委員、国際連携委員 2017-04 -- 2018-03 フロンティア医科学専攻 運営委員、教務委員、国際連携委員、財務委員 2013-04 -- 2017-03 国際室 国際室長、国際戦略会議議長
(Last updated: 2024-08-21)