Matsuzaka Takashi
- Articles
- The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice
Takei Kenta; Han Song-Iee; Murayama Yuki; Satoh Aoi; Oika...
Journal of diabetes investigation/8(4)/pp.446-452, 2017-07 - A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes
Nishi-Tatsumi Makiko; Yahagi Naoya; Takeuchi Yoshinori; T...
FEBS letters/591(7)/pp.965-978, 2017-04 - Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity
Zhao Hui; Matsuzaka Takashi; Nakano Yuta; Motomura Kaori...
Diabetes/66(7)/pp.1833-1846, 2017-07 - A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling
Muranaka H; Hayashi A; Minami K; Kitajima S; Kohno S; Nis...
Oncogenesis/6(6)/pp.e350-e350, 2017-06 - Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features.
Y Owada; T Tamura; T Tanoi; Y Ozawa; Y Shimizu; K Hisaku...
Pathol Int./68(1)/pp.12-22, 2018-01 - A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.
X Piao; N Yahagi; Y Takeuchi; Y Aita; Y Murayama; Y Sawa...
FEBS Let/592(3)/pp.422-433, 2018-02 - The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.
Araki Masaya; Nakagawa Yoshimi; Oishi Asayo; Han Song-Ie...
International Journal of Molecular Sciences/19(7), 2018-07 - 脂肪酸伸長酵素・不飽和化酵素によるリポクオリティ制御
松坂 賢; 島野 仁
実験医学（増刊「脂質クオリティ」）/36(10)/pp.1631-1638, 2018-06 - Evaluation of safety for hepatectomy in a novel mouse model with nonalcoholic-steatohepatitis
Ozawa Yusuke; Tamura Takafumi; Owada Yohei; Shimizu Yosh...
WORLD JOURNAL OF GASTROENTEROLOGY/24(15)/pp.1622-1631, 2018-04 - Transgenic mice overexpressing SREBP-1a in male ob/ob mice exhibit lipodystrophy and exacerbate insulin resistance
Ohno Hiroshi; Matsuzaka Takashi; Tang Nie; Sharma Rahul; ...
Endocrinology/159(6)/pp.2308-2323, 2018-06 - Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry
Sawada Yoshikazu; Izumida Yoshihiko; Takeuchi Yoshinori; ...
Biochemical and biophysical research communications/493(1)/pp.40-45, 2017-09 - Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity
Zhao Hui; Matsuzaka Takashi; Nakano Yuta; Motomura Kaori...
Diabetes/66(7)/pp.1833-1846, 2017-05 - Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice
Takei Kenta; Nakagawa Yoshimi; Wang Yunong; Han Song-...
Journal of pharmacological sciences/133(4)/pp.214-222, 2017-04 - A novel role for the CRTC2 in lipid homeostasis.
Matsuzaka Takashi
Journal of Diabetes Investigation., 2016 - Elovl6 promotes nonalcoholic steatohepatitis
Matsuzaka Takashi; Atsumi Ayaka; Matsumori Rie; Nie Tang; Shi...
HEPATOLOGY/56(6)/pp.2199-2208, 2012-12 - Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
Saito Ryo; Matsuzaka Takashi; Karasawa Tadayoshi; Sekiya ...
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY/31(9)/pp.1973-U143, 2011-09 - Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Saito R; Matsuzaka T; Karasawa T; Sekiya M; Okada N; Igar...
Arterioscler Thromb Vasc Biol/31(9)/p.Sep-73, 2011 - Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
Matsuzaka Takashi; Shimano Hitoshi; Yahagi Naoya; Kato T...
NATURE MEDICINE/13(10)/pp.1193-1202, 2007-10 - Sterol Regulatory Element-Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
Karasawa Tadayoshi; Takahashi Akimitsu; Saito Ryo; Sekiya...
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY/31(8)/pp.1788-U201, 2011-08 - Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7 alpha (Fbw7 alpha) Causes Hepatosteatosis through Kruppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor gamma 2 (PPAR gamma 2) Pathway but Not SREBP-1c Protein in Mice
Kumadaki Shin; Karasawa Tadayoshi; Matsuzaka Takashi; Ema...
JOURNAL OF BIOLOGICAL CHEMISTRY/286(47)/pp.40835-40846, 2011-11 - Mouse Elovl-6 promoter is an SREBP target
Kumadaki Shin; Matsuzaka Takashi; Kato Toyonori; Yahagi ...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/368(2)/pp.261-266, 2008-04 - Elovl6: a new player in fatty acid metabolism and insulin sensitivity
Matsuzaka Takashi; Shimano Hitoshi
JOURNAL OF MOLECULAR MEDICINE-JMM/87(4)/pp.379-384, 2009-04 - Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha.
Matsuzaka T; Shimano H; Yahagi N; Amemiya-Kudo M; Yoshika...
J Lipid Res/43(1)/p.107-114, 2002-01 - Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.
Matsuzaka T; Shimano H; Yahagi N; Yoshikawa T; Amemiya-Ku...
J Lipid Res/43(6)/p.911-920, 2002-01 - TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin
Naka Ayano; Iida Kaoruko Tada; Nakagawa Yoshimi; Iwasaki ...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/430(2)/pp.664-669, 2013-01 - more...
- The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice