SAITO Tsuyoshi
- Articles
- Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring
Iio Keita; Saitoh Tsuyoshi; Ohshita Ryuichiro; Hino Tsub...
Bioorganic & Medicinal Chemistry Letters/60(15)/pp.128555-128555, 2022-03 - Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands
Iio Keita; Kutsumura Noriki; Nagumo Yasuyuki; Saitoh ...
Bioorganic & Medicinal Chemistry Letters/56(15)/pp.128485-128485, 2022-01 - Cerebral capillary blood flow upsurge during REM sleep is mediated by A2a receptors
Tsai Chia-Jung; Nagata Takeshi; Liu Chih-Yao; Suganuma...
Cell reports/36(7)/p.109558, 2021-08 - Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
Shokirova Hurramhon; Inomata Takenori; Saitoh Tsuyoshi...
SCIENTIFIC REPORTS/11(1), 2021-04 - Anodic Oxidation of Phenols: A Key Step for the Synthesis of Natural Products
Yamamoto Takashi; Saitoh Tsuyoshi; Einaga Yasuaki; Nis...
CHEMICAL RECORD/Epub, 2021-03 - Novel Baeyer–Villiger-type oxidation of 4,5-epoxymorphinan derivatives
Hino Tsubasa; Kutsumura Noriki; Saitoh Tsuyoshi; Yamamoto...
Tetrahedron Letters/63(19)/pp.152714-152714, 2021-01 - Novel Baeyer-Villiger-type oxidation of 4,5-epoxymorphinan derivatives
Hino Tsubasa; Kutsumura Noriki; Saitoh Tsuyoshi; Yamam...
TETRAHEDRON LETTERS/63, 2021-01 - Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine
Nagumo Yasuyuki; Katoh Koki; Iio Keita; Saitoh Tsuyoshi; ...
Bioorganic & Ｍedicinal Chemistry Letters/30(17), 2020-09 - Structure-Activity Relationship between Thiol Group-Trapping Ability of Morphinan Compounds with a Michael Acceptor and Anti-Plasmodium falciparum Activities
Kutsumura N.; Koyama Y.; Saitoh T.; Yamamoto N.; Nagumo ...
Molecules/25(5)/pp.1112-1112, 2020-03 - Essential structure of orexin 1 receptor antagonist YNT-707, part V: Structure-activity relationship study of the substituents on the 17-amino group
Saito Tsuyoshi; Seki Kazunori; Nakajima Ryo; Yamamoto Na...
Bioorg. Med. Chem. Lett./30(3), 2019-12 - Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity
Saitoh Tsuyoshi; Seki Kazunori; Nakajima Ryo; Yamamoto N...
Bioorganic & medicinal chemistry letters/29(18)/pp.2655-2658, 2019-09 - Oxidative Cleavage of the Acyl-Carbon Bond in Phenylacetone with Electrogenerated Superoxide Anions
Zhang Yan; Sugai Tomoya; Yamamoto Takashi; Yamamoto Naos...
CHEMELECTROCHEM/6(16:::SI)/pp.4194-4198, 2019-08 - Electrochemical Pinacol Coupling of Acetophenone Using Boron-Doped Diamond Electrode
Nakahara Kenshin; Naba Keisuke; Saitoh Tsuyoshi; Sugai T...
CHEMELECTROCHEM/6(16:::SI)/pp.4153-4157, 2019-08 - A NOVEL REARRANGEMENT REACTION OF MORPHINAN TO ARYLMORPHAN SKELETONS AND THE PHARMACOLOGIES OF ARYLMORPHAN DERIVATIVES
Yata Masahiro; Kutsumura Noriki; Nagumo Yasuyuki; Yamamot...
HETEROCYCLES/99(1)/pp.134-144, 2019-04 - Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring
Yamamoto Naoshi; Ohrui Sayaka; Okada Takahiro; Saitoh Ts...
Bioorganic & medicinal chemistry/27(8)/pp.1747-1758, 2019-04 - Electrochemical Tryptophan-Selective Bioconjugation
Toyama Eisho; Maruyama Katsuya; Sugai Tomoya; Kondo Mio; ...
<i>ChemRxiv<i/>, 2019-03 - Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function
Korkutata Mustafa; Saitoh Tsuyoshi; Cherasse Yoan; Iok...
Neuropharmacology/144/pp.122-132, 2018-10 - SYNTHESIS OF NOVEL 1,3-DIOXA-5-THIAZATRIQUINANE AND 1-OXA-3,5-DITHIAZATRIQUINANE DERIVATIVES AND THEIR PHARMACOLOGIES
Ohshita Ryuichiro; Kutsumura Noriki; Nagumo Yasuyuki; Yam...
HETEROCYCLES/97(2)/pp.687-695, 2018-09 - Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors
Wang Yibing; Cao Liqin; Lee Chia-Ying; Matsuo Tomohik...
Nature communications/9(1)/p.2041, 2018-05 - Orexin agonist improves inflammation-induced immobility
Uchida Shuntaro; Sakurai Takeshi; Irukayama Yoko T; Og...
Proceedings for Annual Meeting of The Japanese Pharmacological Society/2018/pp.OR23-1, 2018 - Controlled decoration of boron-doped diamond electrodes by electrochemical click reaction (e-CLICK)
Yamamoto Takashi; Akahori Miku; Natsui Keisuke; Saitoh T...
CARBON/130/pp.350-354, 2018-04 - Toward bioluminescence in the near-infrared region: Tuning the emission wavelength of firefly luciferin analogues by allyl substitution
Kitada Nobuo; Saitoh Tsuyoshi; Ikeda Yuma; Iwano Satoshi...
TETRAHEDRON LETTERS/59(12)/pp.1087-1090, 2018-03 - A solvent-directed stereoselective and electrocatalytic synthesis of diisoeugenol
Yamamoto Takashi; Riehl Barbara; Naba Keisuke; Nakahara ...
Chemical communications (Cambridge, England)/54(22)/pp.2771-2773, 2018-03 - Favorskii-Type Rearrangement of the 4,5-Epoxymorphinan Skeleton
Kutsumura Noriki; Koyama Yasuaki; Suzuki Yuko; Tominaga ...
Organic letters/20(6)/pp.1559-1562, 2018-03 - Nonpeptide Orexin-2 Receptor Agonist Attenuates Morphine-induced Sedative Effects in Rats
Toyama Satoshi; Shimoyama Naohito; Tagaito Yugo; Nagase ...
Anesthesiology/128(5)/pp.992-1003, 2018-03 - more...
- Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring