MURATANI Masafumi
- Affiliation
- Institute of Medicine
- Official title
- Professor
- ORCID
- 0000-0002-0276-8000
- URL
- +BJG6I6C>XgcB9aIHJ@J76a68a?E
- Office
- Department of Genome Biology
- Phone
- 029-853-7645
- Fax
- 029-853-3333
- Research fields
Genome biology Molecular biology - Research keywords
Space Life Sciences Laboratory automation Gene regulation Epigenome, epigenetics Genome, genomics - Research projects
Astronaut Digital Twins: the application of iPS cells and artificial intelligence for personalized space medicine 2024-01 -- (current) JAXA/ 細胞外ミトコンドリアと血漿中の細胞外小胞から探る宇宙環境応答 2023 -- 2025 村谷 匡史 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 18,070,000Yen Space life science research to predict the future of life on and beyond Earth 2022-06 -- 2023-03 Masafumi Muratani Tsukuba Innovative Area/ 1,000,000Yen 宇宙飛行士の血漿中核酸エピゲノム解析による宇宙環境応答の統合評価 2020 -- 2022 村谷 匡史 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 17,420,000Yen 宇宙滞在中の液体生検による血漿中核酸のゲノム・エピゲノム解析 2015-04 -- (current) 村谷匡史 JAXA宇宙航空研究開発機構/ライフサイエンスおよび宇宙医学分野の国際宇宙ステーション利用実験 3,000,000Yen 癌特異的クリプティック遺伝子プロモーターの転写サイクルプロファイリング 2015-04 -- (current) 村谷匡史 Japan Society of for the Promotion of Science/科研費補助金 新学術領域研究(公募研究) 11,440,000Yen 肺癌に関わる非コードゲノム制御領域のゲノム・エピゲノム統合解析 2015-04 -- (current) 村谷匡史 Japan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research 23,270,000Yen 前庭系可塑性応答の統合的理解と適応障害対策 2015-07 -- (current) 森田啓之 Japan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas 14,360,000Yen マウスを用いた宇宙環境応答の網羅的解析 2014-02 -- (current) 高橋智 JAXA宇宙航空研究開発機構/ - Career history
2019-03 -- (current) 筑波大学医学医療系教授 2024-12 -- (current) Impact Science Co. Ltd.Reserach Advisor 2018-12 -- (current) Robotic Biology Institute Inc.Research Advisor 2018-12 -- (current) LSI Medience CorporationGenome Science Reserach CenterSenior Research Fellow 2014-02 -- 2019-02 University of TsukubaFaculty of MedicineAssociate Professor 2008-07 -- 2014-01 Genome Institute of SingaporeResearch Associate 2006-09 -- 2008-07 Human Frontier Science ProgramLong-term Fellow 2006-04 -- 2006-09 日本学術振興会海外特別研究員 2005-09 -- 2008-07 Cancer Research UK, London Research InstituteResearch Fellow 2005-04 -- 2005-09 Cold Spring Harbor LaboratoryPostdoc - Academic background
2000-08 -- 2005-04 Watson School of Biological Sciences, Cold Spring Harbor Laboratyory 1996-04 -- 2000-03 University of Tsukuba College of Biological Sciences Human Biology Course - Degree
2005-04 Ph.D. Watson School of Biological Sciences, Cold Spring Harbor Laboratory 2000-03 B.Sc. University of Tsukuba - Academic societies
2023-08 -- (current) American Geophysical Union 2023-01 -- (current) Sigma Xi 2021-12 -- (current) GeneLab Analysis Working Group 2020-10 -- (current) International Standards for Space Omics Processing (ISSOP) 2020-06 -- (current) American Society for Gravitational and Space Research 2018-08 -- (current) 日本宇宙放射線研究会 2018-08 -- (current) 日本宇宙生物科学会 2017-12 -- 2019-11 Human Genome Organization - Honors & Awards
1999-07 Atsushi Kitaueda Memorial Fund Travel support for Cold Spring Harbor Laboratory Undergraduate Research Program 1998-06 Atsushi Kitaueda Memorial Fund Travel support for summer internship at Rockefeller University - Articles
- Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel
Okamura Yui; Gochi Kei; Ishikawa Tatsuya; Hayashi Tak...
Scientific reports/14(1), 2024-11-20 - A second space age spanning omics, platforms and medicine across orbits
Mason Christopher E; Green James; Adamopoulos Konstant...
Nature/632(8027)/pp.995-1008, 2024-08-01 - Aging and putative frailty biomarkers are altered by spaceflight
Camera Andrea; Tabetah Marshall; Castañeda Veronica; K...
Scientific reports/14(1), 2024-06-11 - Protective alleles and precision healthcare in crewed spaceflight
Rutter Lindsay A; MacKay Matthew J; Cope Henry; Szewcz...
Nature communications/15(1)/p.6158, 2024-07-22 - Variations in S100A8/A12 Gene Expression Are Associated with the Efficacy of Nintedanib and Acute Exacerbation Development in Idiopathic Pulmonary Fibrosis Patients
Arai Naoki; Nakajima Masayuki; Matsuyama Masashi; Mats...
American journal of respiratory cell and molecular biology/69(2)/pp.242-246, 2023-08-01 - Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
McDonald J. Tyson; Kim JangKeun; Farmerie Lily; Johnso...
NATURE COMMUNICATIONS/15(1), 2024-06-11 - Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Cope Henry; Elsborg Jonas; Demharter Samuel; McDonald ...
COMMUNICATIONS MEDICINE/4(1), 2024-06-11 - Spaceflight induces changes in gene expression profiles linked to insulin and estrogen
Mathyk Begum Aydogan; Tabetah Marshall; Karim Rashid; ...
COMMUNICATIONS BIOLOGY/7(1), 2024-06-11 - Astronaut omics and the impact of space on the human body at scale
Rutter Lindsay A.; Cope Henry; MacKay Matthew J.; Herr...
NATURE COMMUNICATIONS/15(1), 2024-06-11 - Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight
Wu Fei; Du Huixun; Overbey Eliah; Kim Jangkeun; Makhi...
NATURE COMMUNICATIONS/15(1), 2024-06-11 - Spatiotemporal expression and control of haemoglobin in space
Borg Josef; Loy Conor; Kim Jangkeun; Buhagiar Alfred; ...
Nature Communications/15(1), 2024-06-11 - Release of CD36-associated cell-free mitochondrial DNA and RNA as a hallmark of space environment response
Husna Nailil; Aiba Tatsuya; Fujita Shin-Ichiro; Saito ...
Nature communications/15(1)/p.4814, 2024-06-11 - Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation
Takuto Hayashi; Shunya Sadaki; Ryosuke Tsuji; Risa Ok...
Stem Cells/42(9)/pp.830-847, 2024-09 - Transcriptome Analysis by RNA Sequencing of Mouse Embryonic Stem Cells Stocked on International Space Station for 1584 Days in Frozen State after Culture on the Ground
Yoshida Kayo; Hada Megumi; Hayashi Masami; Kizu Akane...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES/25(6), 2024-03 - Comparing the effects of microgravity and amyotrophic lateral sclerosis on mouse dorsal root ganglia
Yoshikawa Masaaki; Matsukawa Mutsumi; Oshima Hideki; I...
FRONTIERS IN SPACE TECHNOLOGIES/4, 2023-07-03 - Kinase signalling in excitatory neurons regulates sleep quantity and depth
Kim Staci J; Hotta-Hirashima Noriko; Asano Fuyuki; Kit...
NATURE/612(7940)/pp.512-518, 2022-12-01 - Blood eosinophil phenotype during treatment with mepolizumab in patients with severe eosinophilic asthma
Sakai Chio; Matsuyama Masashi; Nakajima Masayuki; Mats...
Allergology international : official journal of the Japanese Society of Allergology/73(3)/pp.473-476, 2024-04-05 - Association between idiopathic hypersomnia and a genetic variant in the PER3 gene
Cherasse Yoan; Taira Yuki; Rassu Anna Laura; Barateau ...
JOURNAL OF SLEEP RESEARCH/Epub, 2024-01-22 - Themis2 regulates natural killer cell memory function and formation
Nabekura Tsukasa; Deborah Elfira Amalia; Tahara Saeko; ...
NATURE COMMUNICATIONS/14(1)/p.7200, 2023-11-08 - Throwback phenotypes under microgravity provide new insights on physiological adaptation and evolution of life on and beyond Earth
村谷 匡史; Sadier、Alexa
The Cell, 2023-11 - DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions.
Sato Kazuki; Yamashita-Kanemaru Yumi; Abe Fumie; Murat...
Proc Natl Acad Sci U S A., 2021-05 - Caenorhabditis elegans in microgravity: An omics perspective
Scott Amanda; Willis Craig R. G.; Muratani Masafumi; H...
ISCIENCE/26(7), 2023-07-21 - Variations in S100A8/A12 Gene Expression Are Associated with the Efficacy of Nintedanib and Acute Exacerbation Development in Idiopathic Pulmonary Fibrosis Patients
Arai Naoki; Nakajima Masayuki; Matsuyama Masashi; Mats...
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY/69(2)/pp.242-246, 2023-08 - Roles of Peripheral Myelin Protein 22 in the Effects of Chronic Exercise on Bone Metabolism in Mice
Kawao Naoyuki; Kawaguchi Miku; Muratani Masafumi; Taka...
JOURNAL OF BONE AND MINERAL RESEARCH/38(1)/pp.50-50, 2023-02 - Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Nishimura Haruki; Yoshimura Mitsuhiro; Shimizu Makiko; ...
COMMUNICATIONS BIOLOGY/5(1), 2022-09 - more...
- Impact of microgravity and lunar gravity on murine skeletal and immune systems during space travel
- Books
- 第6章 データ解析時のファイルのフォーマット
橋本 幸枝; 関根 郁夫; 村谷 匡史
がんゲノム医療 結果報告書の読み方と患者への伝え方〜エキスパートパネルの実際〜/医学と看護社/pp.40-47, 2020-05 - がんゲノム医療結果報告書の読み方と患者への伝え方〜エキスパートパネルの実際
野口 惠美子; 関根郁夫; 村谷匡史; 千葉 滋
株式会社医学と看護社, 2020-06 - 臨床情報とがんゲノム医療の適応
鈴木 英雄; 関根郁夫; 村谷匡史; 千葉滋; 野口恵美子; 池見亜也子
医学と看護社, 2020
- 第6章 データ解析時のファイルのフォーマット
- Conference, etc.
- Analysis of the plastic changes induced in the soleus muscle under microgravity conditions
諒介 辻; 林 卓杜; 工藤 崇; 藤田 諒; 濱田 理人; 岡田 理沙; 村谷 匡史; 芝 大; ...
74th International Astronautical Congress/2023-10 - 微小重力環境を利用した新規骨格筋制御遺伝子の探索
林 卓杜; 藤田 諒; 岡田 理沙; 濱田 理人; 布施谷 清香; 金井 真帆; 井上 由理; 定木 駿弥; 村谷...
第9回(2023年度)日本筋学会学術集会/2023-08 - 月重力1/6 gは微小重力による筋萎縮を抑制するが、筋線維タイプの変化は抑制しない
林 卓杜; 藤田 諒; 岡田 理沙; 濱田 理人; 布施谷 清香; 金井 真帆; 井上 由理; 定木...
第70回(2023年度)日本実験動物学会総会/2023-05-24--2023-05-26 - Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
50TH EUROPEAN MUSCLE CONFERENCE/2023-09 - 速筋線維を制御する大Maf群転写因子の解析
定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
第10回サルコペニア・フレイル学会大会/2023-11 - Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination
定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
第31回(2023年度)日本運動生理学会大会/2023-08 - 大Maf群転写因子はtype IIb筋線維を制御する主要な因子である
定木 駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 ...
第70回(2023年度)日本実験動物学会総会/2023-05-24--2023-05-26 - SNRNP200は姉妹染色分体の接着と中心体周期の制御に機能する
甲田愛奈; 加藤かざし; 柳下 玲奈; 宇田川里奈; 林優樹; 村谷 匡史; 金俊達; 木村 圭志
第46回 日本分子生物学会年会/2023-12-06--2023-12-08 - Space Radiation Damage Rescued by Inhibition of Key Spaceflight Associated miRNAs
McDonald J. Tyson; Kim JangKeun; Farmerie Lily; Johnso...
American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18 - Spaceflight induces changes in gene expression profiles linked to insulin and estrogen signaling (IN57)
Mathyk Begum; Tabetah Marshall; Karim Rashid; Zaksas ...
American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18 - Cosmic Kidney Disease: A Pan-Omic investigation of the health consequnce of a trip to Mars and back
Siew Keith; Nestler Kevin A.; Nelson Charlotte; D'Ambr...
American Society for Gravity and Space Research (ASGSR) Annual Conference 2023/2023-11-14--2023-11-18 - Space, Adaptation and Evolution: an open science theme for predicting the future of life on and beyond Earth
Muratani Masafumi; Sadier Alexa
12th Annual International Space Station Research and Development Conference/2023-07-31--2023-08-03 - DONSONおよびsororinのpre-mRNAの適切なスプライシングを介した細胞分裂期制御の解明
加藤 かざし; 柳下 玲奈; 林 優樹; 村谷 匡史; 金 俊達; 木村 圭志
第45回日本分子生物学会年会/2022-11-30--2022-12-2 - 宇宙研究からアプローチする適応・進化の理解と地球生命の未来予測
村谷 匡史
第45回日本分子生物学会年会,ワークショップ,クロマチン潜在能に働きかけるエピゲノムと核内構造体/2022-12-01 - Identification and validation of multi-omics frailty biomarkers in human spaceflight
Camera A; Galsinh AS; Kim JK; Barker RJ; Enguita FJ; MN ...
American Society for Gravity and Space Research (ASGSR) Annual Conference 2022/2022-11-09--2022-11-12 - Molecular characterization of space environment responses in internal tissues by cell-free DNA and RNA analysis of plasma samples collected from six astronauts.
Rutter Lindsay; Husna Nailil; Fujita Shin-ichiro; Saito ...
American Society for Gravity and Space Research (ASGSR) Annual Conference 2022/2022-11-09--2022-11-12 - 速筋線維の形成に不可欠な新規制御因子である大Maf転写因子の機能解析
定木駿弥; 藤田 諒; 林 卓杜; 中村 綾乃; 岡村 結; 布施谷 清香; 濱田 理人; 蕨 栄治; 久野 朗広...
日本分子生物学会年会/2022-12 - 月重力による骨格筋可塑性への影響
林 卓杜; 藤田 諒; 岡田理沙; 濱田理人; 布施谷清香; 金井真帆; 井上由理; 定木駿弥; 村谷匡史; 蕨栄治; 工藤 崇...
第95回日本生化学会大会/2022-11-09--2022-11-11 - Lunar Gravity Prevents Skeletal Muscle Atrophy, But Not Muscle Fiber Type Transition
HAYASHI Takuto; Fujita Ryo; Okada Risa; Hamada Michito; S...
15th Annual Wernher von Braun Memorial Symposium/2022-10-26--2022-10-28 - Tissue deconvolution and cross-species analysis of plasma cell-free RNA highlight homeostatic throwback phenotypes in space
Rutter Lindsay; Husna Nailil; Aiba Tatsuya; Fujita Shin-...
ISS R&D Conference 2022/2022-07-25--2022-07-28 - 糖鎖医学に根ざした透析腎癌のバイオマーカー探索
川西 邦夫; 岡谷 千晶; 藤田 晋一郎; 村谷 匡史; 佐藤 隆; 加藤 光保; 梶 裕之; 久野 敦
第11回腎不全研究会/2021-11-20 - シアル酸生物学からみた後天性嚢胞腎随伴性腎細胞癌の新規バイオマーカー開発
川西 邦夫; 岡谷 千晶; 藤田 晋一郎; 村谷 匡史; 佐藤 隆; 加藤 光保; 梶 裕之; 久野 敦
第11回分子腎臓フォーラム/2021-09-18 - 大Maf転写因子は速筋線維を制御する主要な因子である
定木駿弥; 藤田 諒; 林卓杜; 中村綾乃; 岡村結; 布施谷清香; 濱田理人; 蕨栄治; 久野朗広; 村谷匡史; 岡田理沙; 芝大; ...
第8回日本筋学会学術集会/2022-08-05--2022-08-06 - 宇宙飼育マウスを用いた新規骨格筋萎縮関連遺伝子の探索
加藤 千尋; 林 卓杜; 定木 駿弥; 鈴木 陸; 布施谷 清香; 村谷 匡史; 岡田 理沙; 芝 大; 藤田 ...
第94回日本生化学会大会/2021-11-03 - 微小重力下でのNrf2によるヒラメ筋可塑性制御機能
林 卓杜; 工藤 崇; 藤田 諒; 藤田 晋一郎; 布施谷 清香; 鈴木 陸; 濱田 理人; 岡田 理沙; 村谷 ...
第94回日本生化学会大会/2021-11-03 - more...
- Analysis of the plastic changes induced in the soleus muscle under microgravity conditions
- Teaching
2024-04 -- 2024-08 Special Research in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Humanics IIIb University of Tsukuba. 2024-10 -- 2025-02 Basic Experiments in Human Biology University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Human Biology I University of Tsukuba. 2024-10 -- 2025-02 Special Lectures in Humanics IIIb University of Tsukuba. 2024-04 -- 2024-08 Special Lectures in Humanics IIIa University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Human Biology II University of Tsukuba. 2024-10 -- 2025-02 Special Lectures in Human Biology II University of Tsukuba. 2024-10 -- 2025-02 Special Research in Human Biology II University of Tsukuba. more... - Other educational activities
2022-08 -- (current) Virtual Summer Course 2022 Faculty of Pharmacy Universitas Indonesia 2018-01 -- 2018-01 Bioinformatics Course 筑波大学、Biotechnology Center, Ho Chi Minh City, Vietnam 2017-02 -- 2017-02 Bioinformatics Course 筑波大学、Biotechnology Center, Ho Chi Minh City, Vietnam 2016-01 -- 2016-01 Molecular Biology Course 筑波大学、Science University, Ho Chi Minh City, Vietnam 2016-10 -- 2016-10 出張講義 麗澤高校 2015-11 -- 2015-11 初級者向けインフォマティクス講習会 新学術領域「転写サイクル」 2015-09 -- 2015-09 インフォマティクス講習会 JAXAプロジェクト研究者 - Talks
- Space life science research to predict the future of life on and beyond Earth
村谷 匡史
GeneLab Analysis Working Group Symposium 2022/2022-06-30 - 網羅的遺伝子診断の方向性- NGS次世代遺伝子解析と病理検査 -
Muratani Masafumi
第7回病理技術向上講座/2018-02-13--2018-02-13 - 微量検体ゲノム・エピゲノム解析の環境ストレス研究への応用
村谷 匡史
第14回日本予防医学会学術総会/2016-06-18--2016-06-19 - 臨床検体のゲノム・エピゲノム統合解析で探る疾患メカニズム
村谷 匡史
第34回分子病理学研究会 神戸シンポジウム/2015-07-25--2015-07-26 - Ectopic induction of developmental gene regulatory network by cryptic promoters in gastric cancer
村谷 匡史
Joint International Symposium on TGF-β and Cancer/2015-01-12--2015-01-13
- Space life science research to predict the future of life on and beyond Earth
- Professional activities
2023-09 -- (current) JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE 科学者生活委員会 2023-09 -- (current) JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE 長期構想委員会 2023-09 -- (current) JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE 編集委員会 2023-09 -- (current) JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE 理事 2023-01 -- (current) International Standards for Space Omics Processing (ISSOP) Co-Chair 2022-09 -- (current) The Japanese Society for Biological Sciences in Space 若手研究者育成委員会 2022-09 -- (current) JAPANESE SOCIETY FOR BIOLOGICAL SCIENCES IN SPACE 代議員 2020-10 -- (current) International Standards for Space Omics Processing (ISSOP) Japan contact 2015-12 -- 2019-03 新学術領域「宇宙に生きる」 若手の会幹事会 - University Management
2022-04 -- (current) 医学医療系 施設・設備委員会 委員 2016-04 -- (current) 医学医療系 広報・情報委員会 委員(生命医科学域) 2014-04 -- (current) つくばヒト組織バイオバンクセンター運営委員会 委員
(Last updated: 2024-12-03)