TAKEI Yosuke

Affiliation
Institute of Medicine
Official title
Professor
Sex
Male
Birth date
1964-08
KAKEN ID
20272487
URL
Email
+NI6@:>XgcB9aIHJ@J76a68a?E
Office
Laboratory of Anatomy and Neuroscience
Phone
029-853-3100
Research fields
General anatomy (including histology/embryology)
Psychiatric science
Cell biology
Research projects
IL-17シグナリングを介した大脳皮質-視床フィードバック回路の発達制御2025 -- 2028武井 陽介Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)4,680,000Yen
Elucidation of the mechanism of IL-17A receptor transport focusing on molecular motors2022-04 -- 2025-03TAKEI YosukeJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)4,290,000Yen
特定のT細胞サブセットによる中枢神経障害の解明2019-04 -- 2024-03TAKEI YosukeJapan Society for the Promotion of Science (JSPS)/Grant-in-Aid for Scientific Research (C)4,420,000Yen
Analysis of molecular-motor in animal models2018-04 -- 2019-03Kiyoto KASAIJapan Agency for Medical Research and Development (AMED)/脳科学研究戦略推進プログラム (分担者)10,400,000Yen
Analysis of molecular-motor in animal models2017-04 -- 2018-03Kiyoto KASAIJapan Agency for Medical Research and Development (AMED)/脳科学研究戦略推進プログラム (分担者)10,400,000Yen
スパイン内NMDA受容体輸送機構の解明2016-04 -- 2017-03Yosuke TAKEIthe Uehara memorial foundation/助成金5,000,000Yen
Analysis of molecular-motor in animal models2016-04 -- 2017-03Kiyoto KASAIThe Japan Agency for Medical Research and Development (AMED)/脳科学研究戦略推進プログラム (分担者)10,400,000Yen
Analysis of molecular-motor in animal models2015-04 -- 2016-03Kiyoto KASAIThe Japan Agency for Medical Research and Development (AMED)/脳科学研究戦略推進プログラム (分担者)10,000,000Yen
Career history
1990-06 -- 1992-03東京大学医学部附属病院 精神神経科 研修医
1995-04 -- 1997-03東京大学薬学部 機能病態学教室助手相当(寄付講座教員)
1997-04 -- 2003-03東京大学大学院医学系研究科 細胞生物・解剖学講座助手
2003-04 -- 2007-03東京大学大学院医学系研究科 細胞生物・解剖学講座助教授
2007-04 -- 2015-06東京大学大学院医学系研究科 細胞生物・解剖学講座准教授
2015-07 -- (current)筑波大学医学医療系教授
Academic background
1984-04 -- 1990-03東京大学 医学部 医学科
1992-04 -- 1995-04東京大学 大学院医学系研究科 解剖学
Degree
1998-05博士(医学)東京大学
Licenses and qualifications
1990-05医師免許
Academic societies
2016-09 -- (current)Japanese Society of Biological Psychiatry
1996 -- (current)Japanese Association of Anatomists
1996 -- (current)THE JAPAN NEUROSCIENCE SOCIETY
Articles
  • IL-17A-mediated Neuroimmune Dysregulation in the CNS: Implications for Psychiatric Disease Pathogenesis
    Sanaka Sae; Kamiya Sara; Kubo Asumi; Nakamura Kenyu; ...
    JOURNAL OF PHYSIOLOGICAL SCIENCES/pp.446-446, 2025-03-17
  • Enhanced maternal ROR γt enhances the effect of poly (I:C) in inducing fetal loss.
    Sasaki Tetsuya; Kubo Adumi; Kamiya Sara; Higuchi Koki...
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY/169, 2025-06
  • Elucidation of the role of psychiatric disorder-related kinesins in microglial morphology
    Mitsuhiro Hyugaji; Suguru Iwata; Yohei Soga; Momo Morika...
    Proceeding of the 48th Annual Meeting of the Japan Neuroscience Society, 2025-07-24
  • KIF1Bα mutation causes early-onset Charcot-Marie-Tooth disease with atypical neurological symptoms
    Takaishi Sara; Morikawa Momo; Iwata Suguru; Sasaki Te...
    Proceeding of the 48th Annual Meeting of the Japan Neuroscience Society, 2025-07-24
  • Spatiotemporal analysis of IL-17RA/RC expression in the cerebral cortex: examination of neuroimmunological links using a model of ASD
    Kubo Asumi; Kamiya Sara; Sanaka Sae; Nakamura Kenyu; ...
    JOURNAL OF PHYSIOLOGICAL SCIENCES/pp.447-447, 2025-07-24
  • Exploring the novel functions of the axon guidance molecules in neuronal morphogenesis
    Kenyu Nakamura; Sara Kamiya; Sae Sanaka; Asumi Kubo; Yosu...
    Proceeding of the First laboratory exercise report meeting for the 2026 academic year/pp.11-12, 2025-04-18
  • IL-17RA protein localization in the cerebral cortex and changes in an ASD model
    Chikako Sakamoto; Asumi Kubo; Sara Kamiya; Sae Sanaka; Ke...
    Proceeding of the First laboratory exercise report meeting for the 2026 academic year/pp.8-8, 2025-04-18
  • Spatiotemporal expression of IL-17RA/RC in the cerebral cortex and analysis of neuro-immune interactions
    Sae Sanaka; Sara Kamiya; Asumi Kubo; Kenyu Nakamura; ...
    Proceedings of the First laboratory exercise report meeting for the 2026 academic year/pp.7-7, 2025-04-18
  • High-speed three-dimensional cross-sectional measurement of cultured neurons by scatterometry that improves resolution by an order of magnitude
    岩田 卓; 星野 鉄哉; 青木 貞雄; 武井 陽介; 伊藤 雅英
    Optics Express/33(5)/pp.11398-11408, 2025-03
  • Neuroimmune Interactions in Autism Spectrum Disorder: IL-17A-dependent Microglial Modulation and Pathophysiology
    左中 彩恵; 佐々木 哲也; 武井 陽介
    Clinical psychiatry/67(3), 2025-07
  • Expression patterns of IL-17 receptors in the cerebral cortex during postnatal development and its alteration by maternal immune activation.
    Sasaki Tetsuya; Kamiya Sara; Kishi Kyoko; Iwata Sugur...
    The international journal of neuropsychopharmacology/28(1)/pp.i259-i259, 2025-02
  • Elucidation of the role of the schizophrenia-related kinesin KIF17 in microglial morphological changes.
    Mitsuhiro Hyugaji; Tetsuya Sasaki; Momo Morikawa; Sugu...
    Tsukuba Journal of Biology/24(1)/pp.50-50, 2025-02
  • Effects of visual memory on aggression in mice by glutamate receptors in the brain.
    篠田 希乃佳; 佐々木 哲也; 武井 陽介
    The final report of the ARE for the 2024 academic year, 2025-02
  • Mechanisms of psychiatric disease onset by activation of maternal immune response.
    坂本 智佳子; 佐々木 哲也; 武井 陽介
    The final report of the ARE for the 2024 academic year, 2025-02
  • Gene expression of psychiatric disorder-related kinesin superfamily proteins (Kifs) is potentiated in alternatively activated primary cultured microglia
    Iwata Suguru; Hyugaji Mitsuhiro; Soga Yohei; Morikawa ...
    BMC research notes/18(1)/p.44, 2025-01-30
  • 大脳皮質におけるIL-17RA mRNA 発現動態と ASD 動物モデルにおけるその変化
    久保 明澄; 神谷 沙羅; 中村 賢祐; 樋口 浩輝; 左中 彩恵; 岸 恭子; 武井 陽介; 佐々...
    DOHad Research/12(3)/pp.186-186, 2025-01
  • Spatiotemporal analysis of IL-17RA/RC expression in the cerebral cortex: examination of neuroimmunological links using a model of psychiatric disorders.
    Asumi Kubo; Momo Morikawa; Suguru Iwata; Tetsuya Sasa...
    Tsukuba Journal of Biology/24(1)/pp.51-51, 2025-02
  • SLIT2 is preferentially expressed in the higher-order association area of primate cortex: Functional Implications through Co-expression with RBP4/PNMA5
    Sasaki Tetsuya; Kamiya Sara; Kenyu Nakamura; Sanaka S...
    JOURNAL OF PHYSIOLOGICAL SCIENCES/pp.588-588, 2025-03-17
  • Localization Properties and Regulatory Mechanisms of ASD Risk Factor Myosin Id in Hippocampal Neurons
    Nakamura Kenyu; Higuchi Koki; Sanaka Sae; Sakamoto Ch...
    JOURNAL OF PHYSIOLOGICAL SCIENCES/pp.445-445, 2025-03-17
  • IL-17A-mediated Neuroimmune Dysregulation in the CNS: Implications for Psychiatric Disease Pathogenesis
    Sanaka Sae; Kamiya Sara; Kubo Asumi; Nakamura Kenyu; ...
    JOURNAL OF PHYSIOLOGICAL SCIENCES/pp.446-446, 2025-03-17
  • The Role of Immune Molecules in Central Nervous System Development and Their Dysregulation in ASD.
    Sara Kamiya; Asumi Kubo; Kenyu Nakamura; Koki Higuchi...
    DOHad Research/12(3)/pp.186-186, 2025-01
  • Expression Dynamics of IL-17RA mRNA in the Cerebral Cortex and Its Changes in Animal Models of ASD.
    Asumi Kubo; Sara Kamiya; Koki Higuchi; Kenyu Nakamura...
    DOHad Research/12(3)/pp.186-186, 2025-01
  • A case report of an Adachi-Williams type CG plus H aortic arch anomaly and implications for the development of the cervicothoracic circulation
    Yoshihara Masaharu; Watabe Yoshitoku; Morikawa Momo; I...
    Folia Morphologica, 2024-10
  • Microstructural abnormalities of the cerebral cortex and autism spectrum disorders: from human pathology to animal models
    Sae Sanaka; Koki Higuchi; Kenyu Nakamura; Momo Morika...
    Medical Science Digest, 2024-09
  • IL-17A mRNA expression in the cerebral cortex during postnatal development and its alternations in an animal model of ASD
    Sara Kamiya; Yosuke Takei; Suguru Iwata; Tetsuya Sasaki
    Tsukuba Journal of Biology/23(1), 2024-02
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Conference, etc.
  • Welcome to the Department of Anatomy — An Invitation to Explore the Human Body
    Tetsuya Sasaki; Momo Morikawa; Suguru Iwata; Yosuke T...
    The 2nd Poster Presentation of the Faculty of Medicine, 2025/2025-10-10--2025-12-27
  • Investigating the Role of KIF17 in Schizophrenic Behaviour in Mice
    Halim Stephanie Arsanti; Morikawa Momo; Sasaki Tetsuya...
    2025 Presentation of research plans by third-year students in international medical science/2025-09-01--2025-09-02
  • Neuroanatomical Distribution and Subcellular Localization of the IL-17A Receptor.
    Itagaki Kentaro; Morikawa Momo; Iwata Suguru; Sasaki ...
    2025 Presentation of research plans by third-year students in international medical science/2025-09-01--2025-09-02
  • Elucidation of the mechanism of mental disorder onset by IL-17A-induced neuroimmunoregulatory abnormalities
    Sae Sanaka; Asumi Kubo; Sara Kamiya; Kenyu Nakamura; ...
    BPCNPNP2025/2025-11-13--2025-11-15
  • KIF1Bα mutation causes early-onset Charcot-Marie-Tooth disease with atypical neurological symptoms
    Sara Takaishi; Momo Morikawa; Suguru Iwata; Tetsuya S...
    BPCNPNP2025/2025-11-13--2025-11-15
  • Exploration of a new function of axon guidance factor SLIT/ROBO in neural cell morphogenesis
    Kenyu Nakamura; Asumi Kubo; Sae Sanaka; Kyoko Kishi; ...
    BPCNPNP2025/2025-11-13--2025-11-15
  • Neuroanatomical Localization of the Inflammatory Cytokine Receptor IL-17RA and Its Implication in Autism Spectrum Disorder
    Itagaki Kenetaro; Nakamura Kenyu; Kubo Asumi; Sanaka ...
    TSUKUBA CONFERENCE 2025/2025-10-01--2025-10-03
  • IL-17RA/RC as a Neuroimmune Interface in Cortical Maturation and Autism Pathophysiology
    Kubo Asumi; Kamiya Sara; Sanaka Sae; Nakamura Kenyu; ...
    TSUKUBA CONFERENCE 2025/2025-10-01--2025-10-03
  • Elucidation of the developmental dependence of receptor expression dynamics in neuroimmunological interactions and their contribution to mental disorders
    Asumi Kubo; Momo Morikawa; Suguru Iwata; Yosuke Takei...
    2025 Master's Thesis Research Plan Presentation/2025-07-10--2025-07-10
  • Elucidation of the role of psychiatric disorder-related kinesins in microglial morphology
    Mitsuhiro Hyugaji; Suguru Iwata; Yohei Soga; Momo Mor...
    The 48th Annual Meeting of the Japan Neuroscience Society/2025-07-24--2025-07-27
  • KIF1Bα mutation causes early-onset Charcot-Marie-Tooth disease with atypical neurological symptoms
    Takaishi Sara; Morikawa Momo; Iwata Suguru; Sasaki Te...
    The 48th Annual Meeting of the Japan Neuroscience Society/2025-07-24--2025-07-27
  • Spatiotemporal analysis of IL-17RA/RC expression in the cerebral cortex: examination of neuroimmunological links using a model of ASD
    Kubo Asumi; Kamiya Sara; Sanaka Sae; Nakamura Kenyu; ...
    The 48th Annual Meeting of the Japan Neuroscience Society/2025-07-24--2025-07-27
  • Temporal and spatial mapping of IL-17 receptor expression in the cerebral cortex: Analysis using an ASD model
    Sasaki Tetsuya; Kamiya Sara; Kubo Asumi; Nakamura Ken...
    Neuroscinece2025 (Annual Meeting of Society for Neuroscience)/2025-11-15--2025-11-19
  • Spatiotemporal expression of IL-17RA/RC in the cerebral cortex and analysis of neuro-immune interactions
    Sae Sanaka; Sara Kamiya; Asumi Kubo; Kenyu Nakamura; ...
    First laboratory exercise report meeting for the 2026 academic year/2025-04-18--2025-04-18
  • IL-17RA protein localization in the cerebral cortex and changes in an ASD model
    Chikako Sakamoto; Asumi Kubo; Sara Kamiya; Sae Sanaka...
    First laboratory exercise report meeting for the 2026 academic year/2025-04-18--2025-04-18
  • Exploring the novel functions of the axon guidance molecules in neuronal morphogenesis
    Kenyu Nakamura; Sara Kamiya; Sae Sanaka; Asumi Kubo; ...
    First laboratory exercise report meeting for the 2026 academic year/2025-04-18--2025-04-18
  • Effects of Antipsychotic Drugs on Microglia in a Schizophrenia Model
    曽我 鷹平; 岩田 卓; 佐々木 哲也; 神谷 沙羅; 樋口 浩輝; 武井 陽介
    The 45th Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP)/2023-11-06--2023-11-07
  • The role of maternal immune molecules in the formation of the fetal cerebral cortex and their abnormalities in psychiatric disorders.
    神谷沙羅; 久保明澄; 中村賢祐; 樋口浩輝; 佐々木 哲也; 武井 陽介
    The 12th Annual Meeting of The Japan Society of Developmental Origins of Health and Disease/2023-08-01--2024-08-03
  • Elucidation of the role of the schizophrenia-related kinesin KIF17 in microglial morphological changes
    Mitsuhiro Hyugaji; Momo Morikawa; Tetsuya Sasaki; Sugu...
    Graduation Research Presentation (College of Biology)/2025-02-18--2025-02-18
  • Spatiotemporal analysis of IL-17RA/RC expression in the cerebral cortex: examination of neuroimmunological links using a model of psychiatric disorders.
    Asumi Kubo; Momo Morikawa; Suguru Iwata; Tetsuya Sasa...
    Graduation Research Presentation (College of Biology)/2025-02-18--2025-02-18
  • Past and future of the Laboratory of Anatomy and Neuroscience
    佐々木 哲也; 森川 桃; 岩田 卓; 武井 陽介
    The 3rd poster presentation in 2024 (Division of Life and Medical Sciences)/2025-01-20--2025-02-28
  • Effects of visual memory on aggression in mice by glutamate receptors in the brain.
    篠田希乃佳; 佐々木 哲也; 武井 陽介
    Final ARE Report Meeting/2025-01-20--2025-01-20
  • Mechanisms of psychiatric disease onset by activation of maternal immune response.
    坂本智佳子; 佐々木 哲也; 武井 陽介
    Final ARE Report Meeting/2025-01-20--2025-01-20
  • Analysis of the subcellular localization of the ASD risk gene Myosin Id
    Kenyu Nakamura; Asumi Kubo; Sara Kamiya; Sae Sanaka; ...
    The 112th Annual Meeting of the Kanto Branch of the Japanese Association of Anatomists./2024-12-01--2024-12-01
  • Distribution of IL-17RA mRNA in the developing cortex and its changes in animal models of ASD.
    Asumi Kubo; Sara Kamiya; Kenyu Nakamura; Koki Higuchi...
    The 112th Annual Meeting of the Kanto Branch of the Japanese Association of Anatomists./2024-12-01--2024-12-01
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Intellectural property rights
  • 軟 X 線回折の波長依存性を用いた厳密な3次元断面形状計測
    伊藤 雅英; 岩田 卓; 武井 陽介; 青木 貞雄; 星野 鉄哉
Teaching
2025-04 -- 2025-06Clinical AnatomyUniversity of Tsukuba.
2025-10 -- 2026-02Lecture and Discussion in Molecular Medical Sciences IIUniversity of Tsukuba.
2025-04 -- 2025-08Lecture and Discussion in Molecular Medical Sciences IUniversity of Tsukuba.
2025-10 -- 2026-02Practice in Molecular Medical Sciences IIUniversity of Tsukuba.
2025-04 -- 2025-08Practice in Molecular Medical Sciences IUniversity of Tsukuba.
2025-10 -- 2026-02Seminar in Molecular Medical Sciences IIUniversity of Tsukuba.
2025-04 -- 2025-08Seminar in Molecular Medical Sciences IUniversity of Tsukuba.
2025-10 -- 2026-03Neuroscience Dissertation Research 6University of Tsukuba.
2025-04 -- 2025-09Neuroscience Dissertation Research 5University of Tsukuba.
2025-10 -- 2026-03Neuroscience Dissertation Research 4University of Tsukuba.
more...
Other educational activities
2018-04 -- (current)日本保健医療大学 非常勤講師
2017-08 -- (current)茨城県立盲学校 非常勤講師
2011 -- (current)東京医科歯科大学非常勤講師 (神経解剖学特別講義)
2016 -- 2016東京大学医学系研究科非常勤講師
Talks
  • 精神神経疾患の動物モデル研究と解剖学教育
    武井 陽介
    生命医科学域令和元年度公開講演会/2019-12-20--2019-12-20
  • 精神疾患動物モデルの開発~新しい治療法と予防法を目指して~
    武井 陽介
    豊後荘病院 第20回 Veritus Club/2019-04-17
  • 細胞内輸送と統合失調症モデル動物
    武井 陽介
    医学医療系研究発表会/2016-10-27
  • 神経伝達と可塑性の基盤となる細胞内輸送メカニズム
    武井 陽介
    つくばブレインサイエンス・セミナー/2015-10-27
  • 神経細胞における微小管系細胞骨格蛋白の機能
    武井 陽介
    筑波大学解剖学特別講演会/2015-2-13
Professional activities
2020-04 -- (current)篤志解剖全国連合会団体部会監事
2015-09 -- (current)Japanese Association of Anatomists代議員
2019-04 -- 2022-03Japanese Association of Anatomists若手育成委員会 委員長
2017-04 -- 2019-03日本解剖学会賞・研究費候補者選考委員
2006 -- 2010日本細胞生物学会評議員
University Management
2022-04 -- (current)医学類長
2016-04 -- (current)医学類 神経系コースコーディネータ
2016-04 -- (current)医学類 解剖学コースコーディネータ
2021-04 -- (current)医学医療系 広報・情報委員会委員
2020-04 -- (current)医学医療系 運営委員会委員
2019-04 -- (current)アドミッションセンター運営委員会委員
2020-04 -- (current)感性認知脳科学専攻 財務委員会委員長
2020-04 -- (current)感性認知脳科学専攻 学生表彰委員会委員長
2020-04 -- 2021-04ニューロサイエンス学位プログラム(前期・後期) 学位プログラムリーダー
2017-04 -- 2021-03M2 総コーディネータ―
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Other activities
2019-08 -- 2019-08江戸川取手高校 筑波大学 医学群 連携講義
2019-07 -- 2019-07令和1年度医学・歯学教育指導者のためのワークショップ(文部科学省主宰)に参加
2018-10 -- 2018-10駿台予備校市ヶ谷校 全国国公立大学医学部医学科説明会にて講演
2018-09 -- 2018-09第38回「国内医科大学視察と討論の会」(岡山大学)参加
2018-07 -- 2018-07平成30年度医学・歯学教育指導者のためのワークショップ(文部科学省主宰)に参加
2017-07 -- 2017-07平成29年度医学・歯学教育指導者のためのワークショップ(文部科学省主宰)に参加
2016-11 -- 2016-11河合塾麹町校『全国国公立大学医学部医学科入試相談会』にて講演
2015-07 -- (current)筑波白菊会 理事
2015-07 -- (current)篤志解剖全国連合会 代議員

(Last updated: 2024-10-30)