SAIKI Shinji
- Articles
- 【細胞内のリノベーション機構 タンパク質分解系による生体制御 ユビキチン、プロテアソーム、オートファジー、調節性プロテアーゼによる恒常性維持・刷新の新機構と、疾患への関与から創薬戦略まで】(第5章)細胞内分解を標的とした創薬 オートファジーをターゲットとした創薬
斉木 臣二
実験医学/29(12)/pp.2042-2046, 2011-08 - Novel pathogenic mutations and copy number variations in the VPS13A Gene in patients with chorea-acanthocytosis
Tomiyasu Akiyuki; Nakamura Masayuki; Ichiba Mio; Ueno ...
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics/156(5)/pp.620-631, 2011-07 - The Pathogenesis of Parkinson disease (PD): A hint from gene products for Familial PD
Hattori Nobutaka; Eguchi Hiroto; Saiki Shinji; Usami ...
NEUROSCIENCE RESEARCH/71/pp.E27-E27, 2011 - Lysosomal positioning coordinates cellular nutrient responses
Korolchuk Viktor I.; Saiki Shinji; Lichtenberg Maike; H. ...
NATURE CELL BIOLOGY/13(4)/pp.453-U242, 2011-04 - Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition
Saiki Shinji; Sasazawa Yukiko; Imamichi Yoko; Kawajiri...
AUTOPHAGY/7(2)/pp.176-187, 2011-02 - Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects
Amo Taku; Sato Shigeto; Saiki Shinji; Wolf Alexander M.; ...
NEUROBIOLOGY OF DISEASE/41(1)/pp.111-118, 2011-01 - Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD
Kawajiri Sumihiro; Machida Yutaka; Saiki Shinji; Sato ...
NEUROSCIENCE LETTERS/481(2)/pp.88-91, 2010-09 - 神経変性疾患に関する調査研究 家族性パーキンソン病の原因遺伝子PINK1のmitophagy調節機構について
服部 信孝; 河尻 澄宏; 斉木 臣二; 佐藤 栄人; 波田野 琢; 里 史明; 江口 博人
神経変性疾患に関する調査研究 平成21年度 総括・分担研究報告書/pp.168-170, 2010 - PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Matsuda Noriyuki; Sato Shigeto; Shiba Kahori; Okatsu ...
JOURNAL OF CELL BIOLOGY/189(2)/pp.211-221, 2010-04 - PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
Kawajiri Sumihiro; Saiki Shinji; Sato Shigeto; Sato F...
FEBS LETTERS/584(6)/pp.1073-1079, 2010-03 - 【いきなり名医! パーキンソン病Q&A 押さえておきたいポイント33】パーキンソン病の内科的治療 治療薬の使い方とそのコツ パーキンソン病におけるCOMT阻害薬の位置づけは?
斉木 臣二
jmed mook/(4)/pp.66-68, 2009-10 - Extensive hemispheric lesions with radiological evidence of blood-brain barrier integrity in a patient with neuromyelitis optica
Saiki Shinji; Ueno Yuji; Moritani Toshio; Sato Takesh...
JOURNAL OF THE NEUROLOGICAL SCIENCES/284(1-2)/pp.217-219, 2009-09 - Molecular Genetics and Pathogenesis of Parkinson Disease
斉木 臣二; 服部 信孝
NEUROLOGICAL SURGERY/37(6)/pp.531-541, 2009-06 - A neuropathological study of autosomal-dominant chorea-acanthocytosis with a mutation of VPS13A
Ishida Chiho; Makifuchi Takao; Saiki Shinji; Hirose G...
ACTA NEUROPATHOLOGICA/117(1)/pp.85-94, 2009-01 - Huntington's disease: from pathology and genetics to potential therapies
Imarisio Sara; Carmichael Jenny; Korolchuk Viktor; Chen ...
BIOCHEMICAL JOURNAL/412(2)/pp.191-209, 2008-06 - Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Williams Andrea; Sarkar Sovan; Cuddon Paul; Ttofi Evange...
NATURE CHEMICAL BIOLOGY/4(5)/pp.295-305, 2008-05 - A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
Sarkar Sovan; Krishna Gauri; Imarisio Sara; Saiki Shinji...
HUMAN MOLECULAR GENETICS/17(2)/pp.170-178, 2008-01 - Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification
Saiki Misuzu; Saiki Shinji; Sakai Koichiro; Matsunari ...
MOVEMENT DISORDERS/22(7)/pp.1027-1030, 2007-05 - Primary skeletal muscle involvement in chorea-acanthocytosis
Saiki Shinji; Sakai Koichiro; Murata Ken-ya; Saiki Mi...
MOVEMENT DISORDERS/22(6)/pp.848-852, 2007-04 - Varicose veins associated with CADASIL result from a novel mutation in the Notch3 gene
Saiki S.; Sakai K.; Saiki M.; Kitagawa Y.; Umemori T.; Mu...
NEUROLOGY/67(2)/pp.337-339, 2006-07 - Aggregate-prone proteins are cleared from the cytosol by autophagy: Therapeutic implications
Williams Andrea; Jahreiss Luca; Sarkar Sovan; Saiki S...
CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 76/76/pp.89-101, 2006 - Induction of humoral responses specific for paraneoplastic cerebellar degeneration-associated antigen by whole recombinant yeast immunization
Saiki M; Sakai K; Saiki S; Kitagawa Y; Nakanishi M; ...
JOURNAL OF AUTOIMMUNITY/24(3)/pp.203-208, 2005-05 - Ictal alteration of 99mTc ECD SPECT imaging in a patient with secondary paroxysmal kinesigenic dyskinesia caused by hyperglycemia
Saiki Misuzu; Saiki Shinji; Gondo Yuichiro; Murata Ke...
Clinical Neurology/45(4)/pp.312-316, 2005-04 - Huntington's disease-like 2 can present as chorea-acanthocytosis
Saiki S; Sakai K; Saiki M; Hirose G
NEUROLOGY/63(5)/pp.939-940, 2004-09 - Chorea-acanthocytosis associated with Tourettism
Saiki Shinji; Hirose Genjiro; Sakai Koichiro; Matsunar...
Movement Disorders/19(7)/pp.833-836, 2004-07 - more...
- 【細胞内のリノベーション機構 タンパク質分解系による生体制御 ユビキチン、プロテアソーム、オートファジー、調節性プロテアーゼによる恒常性維持・刷新の新機構と、疾患への関与から創薬戦略まで】(第5章)細胞内分解を標的とした創薬 オートファジーをターゲットとした創薬