YAMASHITA Yasunobu

Researcher's full information

Articles

• Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates
  Ota Yosuke; Itoh Yukihiro; Kurohara Takashi; Singh Ri...
  ACS medicinal chemistry letters/13(10)/pp.1568-1573, 2022-10-13
  
  PubMed
• Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation
  Itoh Yukihiro; Zhan Peng; Tojo Toshifumi; Jaikhan Pat...
  Journal of medicinal chemistry/66(22)/pp.15171-15188, 2023-11-23
  
  PubMed
• Identification of a Histone Deacetylase 8 Inhibitor through Drug Screenings Based on Machine Learning
  Nurani Atika; Yamashita Yasunobu; Taki Yuuki; Takada ...
  Chemical & pharmaceutical bulletin/72(2)/pp.173-178, 2024-04-01
  
  PubMed
• A Structure-Activity Relationship Study of SNAIL1 Peptides as Inhibitors of Lysine-Specific Demethylase 1
  Takada Yuri; Adachi Kyohei; Fujinaga Yuka; Yamashita ...
  Chemical & pharmaceutical bulletin/72(2)/pp.155-160, 2024-04-01
  
  PubMed
• Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells
  Ota Yosuke; Itoh Yukihiro; Takada Yuri; Yamashita Yas...
  Bioorganic & medicinal chemistry/100, 2024-02-15
  
  PubMed
• Identification of a novel histone H2A mono-ubiquitination-inhibiting cell-active small molecule
  Ni Siyao; Takada Yuri; Ando Takaaki; Yu Shengwang; Ya...
  Bioorganic & medicinal chemistry letters/105, 2024-06-01
  
  PubMed
• Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity
  Iida Tetsuya; Itoh Yukihiro; Takahashi Yukari; Miyake ...
  Chemical & pharmaceutical bulletin/72(7)/pp.638-647, 2024-04-01
  
  PubMed
• Structural optimization of a lysine demethylase 5 inhibitor for improvement of its cellular activity
  Terao Mitsuhiro; Yamashita Yasunobu; Takada Yuri; Itoh...
  Bioorganic & medicinal chemistry/98, 2024-01-15
  
  PubMed
• A Deep-Learning-Aided Drug Screening Based on Visualization of a Hidden Layer as Chemical Space
  Yamashita Yasunobu; Taki Yuuki; Wakabayashi Yoshinori; ...
  ACS medicinal chemistry letters/16(7)/pp.1299-1304, 2025-07-10
  
  PubMed
• A Novel PROTAC G9a/GLP Degrader that Inhibits, Similar to G9a siRNA, the Migration of MCF-7 Breast-Cancer Cells without Affecting Proliferation
  Mukherjee Anirban; Yamashita Yasunobu; Maeda Ryo; Akiy...
  Journal of medicinal chemistry/68(17)/pp.18258-18271, 2025-09-11
  
  PubMed
• Identification of a novel small-molecule inhibitor of heterochromatin protein 1
  Tokuyama Akari; Yamashita Yasunobu; Maeda Ryo; Akiyama...
  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS/131, 2026-02-01
  
  PubMed