Hagiwara Daisuke

Affiliation

Faculty of Life and Environmental Sciences

Official title

Associate Professor

Research fields

Applied microbiology

Bacteriology (including mycology)

Research keywords

環境応答、シグナル伝達、病原性、薬剤耐性、トランスクリプトーム

Degree

2006-03

Ph.D.(Agriculture)

Nagoya University

Academic societies

2019 -- (current)	JAPANESE SOCIETY OF SOIL MICROBIOLOGY
2001 -- (current)	JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
2011 -- (current)	THE JAPANESE SOCIETY FOR MEDICAL MYCOLOGY
2006 -- (current)	Society of Genome Microbiolgy, Japan
2005 -- (current)	Fungal Molecular Biology Society of Japan

Honors & Awards

2019-10	日本医真菌学会奨励賞
2012	糸状菌遺伝子研究会奨励賞

Refereed academic journal/Refereed international conference paper

• Fungal mycelia and bacterial thiamine establish a mutualistic growth mechanism
  Gayan Abeysinghe; Kuchira Momoka; Masuo Shunsuke; Takahas...
  LIFE SCIENCE ALLIANCE/3(12), 2020-09
  PubMed
• Mycovirus-Induced Tenuazonic Acid Production in a Rice Blast FungusMagnaporthe oryzae
  Ninomiya Akihiro; Urayama; Suo Rei; Itoi Shiro; Fuji Shin...
  FRONTIERS IN MICROBIOLOGY/11, 2020-07
  PubMed Tsukuba Repository
• A method for the preparation of electrocompetent cells to transform unicellular green algae, Coccomyxa (Trebouxiophyceae, Chlorophyta) strains Obi and KJ
  Tatara Hiroshi; Sato Yusuke; Kasai Yuki; Hagiwara Daisuke...
  ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS/48, 2020-06
• Viral RNA Genomes Identified from Marine Macroalgae and a Diatom
  Chiba Yuto; Tomaru Yuji; Shimabukuro Hiromori; Kimura Kei...
  Microbes and Environments/35(3), 2020-05
  CiNii PubMed
• Isolation of azole-resistant Aspergillus fumigatus from imported plant bulbs in Japan and the effect of fungicide treatment
  Hagiwara Daisuke
  Journal of Pesticide Science/45(3)/pp.147-150, 2020-05
  CiNii PubMed
• dsRNA-seq Reveals Novel RNA Virus and Virus-Like Putative Complete Genome Sequences from Hymeniacidon sp. Sponge
  Urayama Syun-Ichi; Takaki Yoshihiro; Hagiwara Daisuke; Nu...
  Microbes and environments/35(2), 2020-04
  CiNii PubMed
• Biosynthesis of β-(1→5)-Galactofuranosyl Chains of Fungal-Type and -Mannose-Type Galactomannans within the Invasive Pathogen Aspergillus fumigatus
  Chihara Yuria; Tanaka Yutaka; Izumi Minoru; Hagiwara Dais...
  mSphere/5(1), 2020-04
  PubMed
• The Cell Wall Integrity Pathway Contributes to the Early Stages of Asexual Development
  Rocha Marina Campos; Fabri João Henrique Tadini Marilhano...
  Applied and environmental microbiology/86(7), 2020-03
  PubMed
• Nutritional Heterogeneity Among Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner
  Ries Laure Nicolas Annick; Steenwyk Jacob L; de Castro Pa...
  Frontiers in microbiology/10/p.854, 2019-04
  PubMed
• A Novel Antifungal Compound Z-705 Specifically Inhibits Protein Kinase C of Filamentous Fungi
  Sugahara Asumi; Yoshimi Akira; Shoji Fumio; Fujioka Tomon...
  Applied and environmental microbiology/85(10), 2019-03
  PubMed
• AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus
  Paul Sanjoy; Stamnes Mark; Thomas Grace Heredge; Liu Hong...
  mBio/10(2), 2019-03
  PubMed Tsukuba Repository
• Heterogeneity in Pathogenicity-related Properties and Stress Tolerance in Aspergillus fumigatus Clinical Isolates
  Hagiwara Daisuke; Takahashi Hiroki; Takagi Hiroshi; Watan...
  Medical Mycology Journal/59(4)/pp.E63-E70, 2018-04
  CiNii PubMed
• Current Status of Azole-resistant Aspergillus fumigatus Isolates in East Asia:China, Japan, Korea, and Taiwan
  Hagiwara Daisuke
  Medical Mycology Journal/59(4)/pp.E71-E76, 2018-04
  CiNii PubMed
• Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in
  de Assis Leandro José; Manfiolli Adriana; Mattos Eliciane...
  mBio/9(6), 2018-11
  PubMed Tsukuba Repository
• Emerging Antifungal Drug Resistance in Aspergillus fumigatus and Among Other Species of Aspergillus
  Toyotome Takahito; Hagiwara Daisuke; Takahashi Hiroki; Wa...
  CURRENT FUNGAL INFECTION REPORTS/12(3)/pp.105-111, 2018-09
• Non-cyp51A Azole-Resistant Aspergillus fumigatus Isolates with Mutation in HMG-CoA Reductase
  Hagiwara Daisuke; Arai Teppei; Takahashi Hiroki; Kusuya Y...
  EMERGING INFECTIOUS DISEASES/24(10)/pp.1889-1897, 2018-10
• Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi
  Hagiwara Daisuke; A Watanabe; K Kamei; GH Goldman
  Front Microbiol, 2016-09
  PubMed
• Comparative transcriptome analysis revealing dormant conidia and germination associated genes in Aspergillus species: an essential role for AtfA in conidial dormancy
  Hagiwara Daisuke; H Takahashi; Y Kusuya; S Kawamoto; K Ka...
  BMC Genomics, 2016-05
  PubMed
• Genome-wide transcriptome analysis of Aspergillus fumigatus exposed to osmotic stress reveals regulators of osmotic and cell wall stresses that are SakA(HOG1) and MpkC dependent
  L Pereira Silva; P Alves de Castro; TF Dos Reis; MH Pazia...
  Cell Microbiol, 2017-04
  PubMed
• Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene
  萩原 大祐; Watanabe A; Kamei K
  Sci Rep., 2016-12
  PubMed
• A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions
  Hagiwara Daisuke; D Miura; K Shimizu; S Paul; A Ohba; T G...
  PLoS Pathog, 2017-01
  PubMed
• First clinical isolation report of azole-resistant Aspergillus fumigatus with TR(34)/L98H-type mutation in Japan
  T Toyotome; Hagiwara Daisuke; H Kida; T Ogi; A Watanabe; ...
  J Infect Chemother, 2017-01
  PubMed
• Transcription factor Afmac1 controls copper import machinery in Aspergillus fumigatus
  Y Kusuya; Hagiwara Daisuke; K Sakai; T Yaguchi; T Gonoi; ...
  Curr Genet, 2017-08
  PubMed
• Temperature during conidiation affects stress tolerance, pigmentation, and trypacidin accumulation in the conidia of the airborne pathogen Aspergillus fumigatus
  Hagiwara Daisuke; K Sakai; S Suzuki; M Umemura; T Nogawa;...
  PLoS One, 2017-05
  PubMed
• Azole-resistant Aspergillus fumigatus Containing a 34-bp Tandem Repeat in cyp51A Promoter is Isolated from the Environment in Japan
  K Onishi; B Muhammad Sarumoh; Hagiwara Daisuke; A Watanab...
  Med Mycol J, 2017-05
  PubMed

more...

Other articles

• Phenotypic and Molecular Biological Analysis of Polymycovirus AfuPmV-1M From : Reduced Fungal Virulence in a Mouse Infection Model
  Takahashi-Nakaguchi Azusa; Shishido Erika; Yahara Misa; U...
  Frontiers in microbiology/11, 2020-04
  PubMed
• Discovery of divided RdRp sequences and a hitherto unknown genomic complexity in fungal viruses
  Chiba Yuto; Oiki Sayoko; Yaguchi Takashi; Urayama Syun-Ic...
  Virus evolution/7(1)/p.veaa101, 2021-01
  PubMed
• Diverged and Active Partitiviruses in Lichen
  Urayama Syun-ichi; Doi Nobutaka; Kondo Fumie; Chiba Yuto;...
  FRONTIERS IN MICROBIOLOGY/11, 2020-10
  PubMed

Books

• Aspergillus: Molecular Biology and Genomics
  Daisuke Hagiwara
  Caister Academic Press, 2010-01
• Stress Biology of Yeasts and Fungi: Applications for Industrial Brewing and Fermentation
  Daisuke Hagiwara
  Springer, 2015-02

Conference, etc.

• 真菌細胞内で“家畜化”されたウイルス
  浦山 俊一; 二宮章洋; 千葉悠斗; 池田彩乃; 趙彦杰; 老木紗予...
  第94回日本細菌学会総会/2021-03-23--2021-03-23
• 菌類ウイルスの効率的な治癒株作成法の発見
  池田彩乃; 千葉悠斗; 浦山 俊一; 萩原大祐
  ウイルス学若手研究集会2020/2020-12-19--2020-12-19
• 菌類ウイルスの効率的な治癒株作成法の発見
  池田彩乃; 千葉悠斗; 浦山俊一; 萩原大祐
  ウイルス学若手研究集会2020/2020-12-19--2020-12-19
• 菌類RNAウイルスの持つゲノム構造多様性の探索
  千葉 悠斗; 老木紗代子; 矢口貴志; 浦山 俊一; 萩原大祐
  ウイルス学若手研究集会2020/2020-12-19--2020-12-19
• Aspergillus fumigatusのファルネソール応答機構における一酸化窒素の機能解析
  老木 紗予子; 二宮章洋; 浦山俊一; 萩原 大祐
  2020年度日本農芸化学会大会/2020-03-26
• 産業利用糸状菌における細胞外膜小胞の発見
  岩橋由佳; 浦山俊一; 桝尾俊介; 兼松周作; 高谷直樹; 野村暢...
  2020年度日本農芸化学会大会/2020-03-26
• Trichoderma reeseiによるもみ殻分解に対する微生物叢の影響解析
  岩波 明季; 浦山俊一; 萩原 大祐
  2020年度日本農芸化学会大会/2020-03-26
• トティウイルスによるイネいもち病菌のカビ毒テヌアゾン酸産生誘導
  二宮章洋; 浦山俊一; 周防 玲; 藤晋一; 森山裕充; 萩原 大祐
  2020年度日本農芸化学会大会/2020-03-26
• 共培養によるAspergillus nigerの黄色色素生産誘導の発見
  辻遥佳; 二宮章洋; 甲斐建次; 浦山俊一; 萩原 大祐
  2020年度日本農芸化学会大会/2020-03-26
• Investigation of adaptation to hypoxia in Aspergillus fumigatus
  Bian Cai; Kusuya Yoko; Hagiwara Daisuke; Watanabe Akira; ...
  9th Advances Against Aspergillosis and Mucormycosis/2020-2-27
• Investigation of the molecular mechanisms of copper homeostasis in Aspergillus fumigatus
  Kusuya Yoko; Bian Cai; Hagiwara Daisuke; Yaguchi Takashi;...
  9th Advances Against Aspergillosis and Mucormycosis/2020-2-27
• Characterization of azole resistant Aspergillus fumigatus strains isolated from imported tulip bulbs that were purchased in Japan
  Hagiwara Daisuke
  Asperfest17/2020-02-16
• Secondary metabolic response of Aspergillus nidulans to intimate interaction with Aspergillus fumigatus
  Ninomiya Akihiro; Urayama Syun-ichi; Hagiwara Daisuke
  Asperfest17/2020-02-16
• Characterization of extracellular membrane vesicle in liquid culture of Magnaporthe oryzae and Aspergillus oryzae
  Urayama Syun-ichi; Iwahashi Yuka; Masuo Shunsuke; Kanemat...
  Asperfest17/2020-02-16
• Cellular response to farnesol and the role of nitric oxide production in Aspergillus fumigatus
  Oiki Sayoko; Ninomiya Akihiro; Urayama Syun-ichi; Hagiwar...
  Asperfest17/2020-02-16
• Characterization of azole resistant Aspergillus fumigatus strains isolated from imported tulip bulbs that were purchased in Japan
  Hagiwara Daisuke
  15th European Conference on Fungal Genetics/2020-02-17
• Cellular response to farnesol and the role of nitric oxide production in Aspergillus fumigatus
  Oiki Sayoko; Ninomiya Akihiro; Urayama Syun-ichi; Hagiwar...
  15th European Conference on Fungal Genetics/2020-02-17
• Secondary metabolic response of Aspergillus nidulans to intimate interaction with Aspergillus fumigatus
  Ninomiya Akihiro; Urayama Syun-ichi; Hagiwara Daisuke
  15th European Conference on Fungal Genetics/2020-02-17
• Characterization of extracellular membrane vesicle in liquid culture of Magnaporthe oryzae and Aspergillus oryzae
  Urayama Syun-ichi; Iwahashi Yuka; Masuo Shunsuke; Kanemat...
  15th European Conference on Fungal Genetics/2020-02-17
• Cellular response to antifungals and the role of nitric oxide production in Aspergillus fumigatus
  Oiki Sayoko; Ninomiya Akihiro; Urayama Syun-ichi; Hagiwar...
  The 8th Global Network Forum on Infection and Immunity: Microbiome/2020-01-10
• RNA virus diversity in Aspergillus fumigatus and its related species revealed by deep-sequencing method
  Chiba Yuto; Urayama Syun-ichi; Yaguchi Takashi; Hagiwara ...
  The 8th Global Network Forum on Infection and Immunity: Microbiome/2020-01-10
• Identification of antibiotics produced by Trichophyton rubrum and analysis of the biosynthetic gene
  Masuda Keisuke; Ninomiya Akihiro; Ueno Keigo; Yngihara Ns...
  The 8th Global Network Forum on Infection and Immunity: Microbiome/2020-01-10
• Isolation of azole resistant Aspergillus fumigatus strains from imported plant bulbs in japan
  Hagiwara Daisuke
  The 8th Global Network Forum on Infection and Immunity: Microbiome/2020-01-10
• 輸入植物球根の薬剤耐性ヒト病原真菌による汚染と農薬浸漬処理の効果
  萩原 大祐
  日本農薬学会第45回大会/2020-03-08
• 白癬菌が産生する抗生物質の同定とその生合成遺伝子の解析
  増田 圭恭; 二宮章洋; 矢口貴志; 浦山俊一; 萩原 大祐
  第19回糸状菌分子生物学コンファレンス/2019-11-06

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Teaching

2020-10 -- 2021-02	Seminar in Applied Biochemistry IIF	University of Tsukuba.
2020-10 -- 2021-02	Fungal Interaction and Molecular Biology III	University of Tsukuba.
2020-04 -- 2020-08	Fungal Interaction and Molecular Biology III	University of Tsukuba.
2020-08 -- 2020-09	Specialized Laboratory in Applied Biological Chemistry	University of Tsukuba.
2020-10 -- 2021-02	Research in Applied Biochemistry IIF	University of Tsukuba.
2020-10 -- 2021-02	Research in Fungal Molecular Microbiology I	University of Tsukuba.
2020-04 -- 2020-08	Research in Fungal Molecular Microbiology I	University of Tsukuba.
2020-10 -- 2021-02	Fungal Interaction and Molecular Biology I	University of Tsukuba.
2020-04 -- 2020-08	Fungal Interaction and Molecular Biology I	University of Tsukuba.
2020-10 -- 2021-02	Fungal Interaction and Molecular Biology II	University of Tsukuba.

more...

Professional activities

2019 -- (current)	Frontiers in Microbiology	Associate Editor
2018 -- (current)	PLoS One	Academic Editor
2012 -- 2018	糸状菌分子生物が研究会若手の会	運営委員（会計）

(Last updated: 2020-08-19)