SHIMANO Hitoshi
- Articles
- Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.
Matsuzaka T; Shimano H.; Yahagi N; Yoshikawa T; Amemiya-K...
J Lipid Res/43/p.911-20., 2002-01 - Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules.
Song H; Shojima N; Sakoda H; Ogihara T; Fujishiro M; Kata...
Biochem Biophys Res Commun/299/p.291-8, 2002-01 - Cerebral hemorrhagic infarction after radiation for pituitary adenoma.
Ogaki S; Suzuki S; Suzuki H; Suzuki M; Shimano H.; Toyosh...
Intern Med/41/p.834-8, 2002-01 - Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases.
Okazaki H; Osuga J; Tamura Y; Yahagi N; Tomita S; Shionoi...
Diabetes/51/p.3368-75, 2002-01 - Insulin up-regulates tumor necrosis factor-alpha production in macrophages through an extracellular-regulated kinase-dependent pathway.
Iida KT; Shimano H; Kawakami Y; Sone H; Toyoshima H; Suzu...
J Biol Chem./276(35)/pp.32531-32537, 2001-08 - Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes.
Shimano H
Progress in Lipid Research/40(6)/pp.439-452, 2001-01 - Neutralization of vascular endothelial growth factor prevents collagen-induced arthritis and ameliorates established disease in mice.(共著)
Sone H; Kawakami Y; Sakauchi M; Nakamura Y; Takahashi A; ...
Biochem Biophys Res Commun/281(2)/p.562-568, 2001-01 - Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice : pleiotropic effects on CD36 expression and HDL.(共著)
Chen Z; Ishibashi S; Perrey S; Osuga Ji; Gotoda T; Kitami...
Arterioscler Thromb Vasc Biol/21(3)/p.372-377, 2001-01 - Asialoglycoprotein receptor deficiency in mice lacking the major receptor subunit. Its obligate requirement for the stable expression of oligomeric receptor.(共著)
Tozawa R; Ishibashi S; Osuga J; Yamamoto K; Yagyu H; Ohas...
J Biol Chem/276(16)/p.12624-12628, 2001-01 - Identification of LXR/RXR as an Activator of the Sterol Regulatory Element-Binding Protein(SREBP)-1c Gene Promoter.(共著)
Yoshikawa T; Shimano H.; Amemiya-Kudo M; Yahagi N; Hasty ...
Mol Cell Biol/21/p.2991-3000, 2001-01 - Severe Hypercholesterolemia, Hypertriglyceridemia and Atherosclerosis in mice Lacking Both Leptin and the Low Density Lipoprotein Receptor.
Hasty AH; Shimano H.; Osuga J; Namatame I; Takahashi A; Y...
J Biol Chem/276/p.37402-37408, 2001-01 - Effects of probucol on atherosclerosis of apoE-deficient or LDL receptor-deficient mice.
Yoshikawa T; Shimano H.; Chen Z; Ishibashi S; Yamada N
Horm Metab Res/33/p.472-9, 2001-01 - Elevated levels of vascular endothelial growth factor in the sera of patients with rheumatoid arthritis correlation with disease activity.
Sone H; Sakauchi M; Takahashi A; Suzuki H; Inoue N; Iida ...
Life sciences/69(16)/pp.1861-1869, 2001-01 - Sterol Regulatory Element-Binding Proteins Induce an Entire Pathway of Cholesterol Synthesis.
Sakakura Y; Shimano H.; Sone H; Takahashi A; Inoue K; Toy...
Biochem Biophys Res Commun/286/p.176-83, 2001-01 - Sterol regulatory element-binding protein-1 as a dominant transcription factor for gene regulation of lipogenic enzymes in the liver Trends in Cardiovascular Medicine
Shimano H
Trends in Cardiovascular Medicine/10/p.275-8, 2000-01 - Sterol regulatory element-binding protein-1 as a dominant transcription factor for gene regulation of lipogenic enzymes in the liver.
Shimano H
Trends in Cardiovascular Medicine/10/p.275-278, 2000-01 - Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins.(共著)
Sato R; Okamoto A; Inoue J; Miyamoto W; Sakai Y; Emoto N...
J Biol Chem/275/p.12497-12502, 2000-01 - Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.(共著)
Yagyu H; Kitamine T; Osuga J; Tozawa R; Chen Z; Kaji Y; O...
J Biol Chem/275/p.21324-21330, 2000-01 - Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.(共著)
Hasty AH; Shimano H.; Yahagi N; Amemiya-Kudo M; Perrey S...
J Biol Chem/275/p.31069-31077, 2000-01 - Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene.(共著)
Amemiya-Kudo M; Shimano H.; Yoshikawa T; Yahagi N; Hasty ...
J Biol Chem/275/pp.31078-31085, 2000-01 - Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes.(共著)
Shimano H.; Yahagi N; Amemiya-Kudo M; Hasty AH; Osuga J; ...
J Biol Chem/274/p.35832-35839, 1999-01 - Absence of Cd36 mutation in the original spontaneously hypertensive rats with insulin resistance [letter].(共著)
Gotoda T; Lizuka Y; Kato N; Osuga J; Bihoreau MT; Murakam...
Nat Genet/22/p.226-228, 1999-01 - Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL.(共著)
Horton JD; Shimano H.; Hamilton RL; Brown MS; Goldstein JL
J Clin Invest/103/p.1067-1076, 1999-01 - A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids.
Yahagi N; Shimano H.; Hasty AH; Amemiya-Kudo M; Okazaki H; Tam...
J Biol Chem/274/pp.35840-35844, 1999-01 - Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver.(共著)
Shimomura I; Shimano H.; Korn BS; Bashmakov Y; Horton JD
J Biol Chem/273/p.35299-35306, 1998-01 - more...
- Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.