SHIMANO Hitoshi

Researcher's full information

Articles
  • Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice.
    Yamamoto K; Shimano H.; Shimada M; Kawamura M; Gotoda T; ...
    Diabetes/44/p.580-585, 1995-01
  • Role of apolipoprotein E in lipoprotein metabolism and in the process of atherosclerosis.
    Yamada N; Shimano H.; Yazaki Y
    J Atheroscler Thromb/2/p.S29-33, 1995-01
  • Effects of platelet-derived growth factor on the synthesis of lipoprotein lipase in human monocyte-derived macrophages.
    Inaba T; Kawamura M; Gotoda T; Harada K; Shimada M; Ohsug...
    Arterioscler Thromb Vasc Biol./15(4)/p.522-528, 1995-01
  • Dextran sulfate, a competitive inhibitor for scavenger receptor, prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits.
    Tsubamoto Y; Yamada N; Watanabe Y; Inaba T; Shiomi M; Shi...
    Atherosclerosis./106(1)/p.43-50, 1994-01
  • Overexpression of human lipoprotein lipase enhances uptake of lipoproteins containing apoliprotein B-100 in transfected cells.(共著)
    Kawamura M; Shimano H.; Gotoda T; Harada K; Shimada M; Oh...
    Arterioscler Thromb/14/p.235-242, 1994-01
  • Establishment of enzyme-linked immunosorbent assays for lipoprotein lipase with newly developed antibodies.
    Kawamura M; Gotoda T; Mori N; Shimano H.; Kozaki K; Harad...
    J Lipid Res./35(9)/p.1688-1697, 1994-01
  • Secretion-recapture process of apolipoprotein E in hepatic uptake of chylimicron remnants in transgenic mice.(共著)
    Shimano H.; Namba Y; Ohsuga J; Kawamura M; Yamamoto K; Sh...
    J Clin Invest/93(5)/p.2215-2223, 1994-01
  • Elevated serum and urinary thrombomodulin levels in patients with non-insulin-dependent diabetes mellitus.
    Shimano H.; Takahashi K; Kawakami M; Gotoda T; Harada K; ...
    Clin Chim Acta./225(2)/p.89-96, 1994-01
  • Metabolism of chylomicron remnants in transgenic mice expressing apolipoprotein E in the intestine.(共著)
    Shimano H.; Namba Y; Ohsuga J; Yamamoto K; Shimada M; Got...
    Biophys Res Commun/200/p.716-721, 1994-01
  • Regulation of low density lipoprotein receptor activity in Chinese hamster ovary cells transfected with the c-fms gene.(共著)
    Yamamoto K; Shimano H.; Inaba T; Gotoda T; Harada K; Shim...
    FEBS Lett/356(1)/p.72-75, 1994-01
  • Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia.(共著)
    Shimada M; Shimano H.; Gotoda T; Yamamoto K; Kawamura M; ...
    J Biol Chem/269/p.11673, 1994-01
  • Increased risk factors for coronary artery disease in Japanese subjects with hyperinsulinemia or glucose intolerance.(共著)
    Yamada N; Yoshinaga H; Sakurai N; Shimano H.; Gotoda T; O...
    Diabetes Care/17/p.107-114, 1994-01
  • Induction of LDL receptor-related protein during the differentiation of monocyte-macrophages. Possible involvement in the atherosclerotic process.
    Watanabe Y; Inaba T; Shimano H.; Gotoda T; Yamamoto K; Mo...
    Arterioscler Thromb/14/p.1000-1006, 1994-01
  • Macrophage colony-stimulating factor regulates both activities of neutral and acidic cholesteryl ester hydrolases in human monocyte-derived macrophages
    Inaba T; Shimano H.; Gotoda T; Harada K; Shimada M; Kawam...
    J Clin Invest/92(2)/p.750-757, 1993-01
  • Effect of macrophage colony-stimulating factor on the development of diabetes mellitus in BB rats.
    Watanabe Y; Inoue I; Inaba T; Shimano H.; Gotoda T; Harad...
    Horm Metab Res./25(6)/p.323-324, 1993-01
  • Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function.
    Inaba T; Shimano H.; Gotoda T; Harada K; Shimada M; Ohsug...
    J Biol Chem./268(32)/pp.24353-24360, 1993-01
  • Mutational analysis of human lipoprotein lipase by carboxy-terminal truncation.(共著)
    Kozaki K; Gotoda T; Kawamura M; Shimano H.; Yazaki Y; Ouc...
    J Lipid Res/34/p.1765-1772, 1993-01
  • Cholesteryl ester transfer protein deficiency caused by a nonsense mutation detected in the patient's macrophage mRNA.
    Gotoda T; Kinoshita M; Shimano H.; Harada K; Shimada M; O...
    Biochem Biophys Res Commun./194(1)/p.519-524, 1993-01
  • Apolipoprotein E metabolism in sciatic nerves of diabetic rats. Implication for diabetic neuropathy.
    Ishibashi S; Mori N; Shimada M; Oka T; Shimano H.; Gotoda...
    Horm Metab Res./25(2)/p.82-87, 1993-01
  • Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM.(共著)
    Murakami K; Shimizu M; Yamada N; Ishibashi S; Shimano H....
    Diabetes Care/16/p.564-569, 1993-01
  • Overexpression of apolipoprotein E in transgenic mice : marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.(共著)
    Shimano H.; Yamada N; Katsuki M; Shimada M; Gotoda T; Har...
    Proc Natl Acad Sci USA/89/p.1750-1754, 1992-01
  • Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells.(共著)
    Inaba T; Gotoda T; Shimano H.; Shimada M; Harada K; Kozak...
    J Biol Chem/267(18)/pp.13107-13112, 1992-01
  • Macrophage colony stimulating factor prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits.(共著)
    Inoue I; Inaba T; Motoyoshi K; Harada K; Shimano H.; Kawa...
    Atherosclerosis/93/p.245-254, 1992-01
  • Plasma lipoprotein metabolism in transgenic mice overexpressing apoliprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.(共著)
    Shimano H.; Yamada N; Katsuki M; Yamamoto K; Gotoda T; Ha...
    J Clin Invest/90(5)/p.2084-2091, 1992-01
  • Expression of M-CSF receptor encoded by c-fms on smooth muscle cells derived from arteriosclerotic lesion.
    Inaba T; Yamada N; Gotoda T; Shimano H.; Shimada M; Momom...
    J Biol Chem./267(8)/p.5693-5699, 1992-01
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