HO Kiong
- Affiliation
- Institute of Medicine
- Official title
- Associate Professor
- URL
- %FDJIBCJ^miH?gONPFP=<g<>gEKt
- Research fields
Parasitology (including sanitary zoology) Functional biochemistry Molecular biology - Research keywords
Parasitology, RNA Processing, RNA ligation, Trypanosoma - Research projects
Structure and biological targets of Trypanosome mRNA recapping enzyme 2021 -- 2023 HO KIONG Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C) 4,290,000Yen Mechanism of mRNA recapping pathway in trypanosome 2016-04 -- 2020-03 HO KIONG JSPS/Grant-in-Aid for Scientific Research(B) 17,290,000Yen Structural, Functional and Genetic Analysis of Archaea RNA Ligase 2011-04 -- 2016-03 Kiong Ho National Science Foundation/Div Of Molecular and Cellular Bioscience 76,500,000Yen Mechanism of mRNA cap formation in Trypanosoma brucei 2006-07 -- 2011-06 HO KIONG American Heart Association/Scientist Development Grant 26,000,000Yen Mechanism of Archaeal RNA ligase 2007-07 -- 2008-09 HO KIONG University at Buffalo/UB2020 Interdisciplinary Research Development Fund 4,000,000Yen - Career history
2003-01 -- 2010-10 State University of New York at BuffaloDepartment of Biological SciencesAssistant Professor 2000-01 -- 2003-10 Sloan Kettering Instite for Cancer ResearchProgram in Molecular BiologySenior Research Scientist 1997-04 -- 1999-12 Sloan Kettering Institute for Cancer ResearchProgram in Molecular BiologyPost-doctoral Fellow - Academic background
1986-09 -- 1990-01 Rutgers University, The State University of New Jersey College of Arts and Sciences Biochemistry 1990-09 -- 1997-03 Cornell University, Weill Graduate School of Medical Sciences Molecular Biology Molecular Biology - Degree
1997-02 Ph.D. Molecular Biology Cornell University, Weill Graduate School of Medical Sciences 1990-1 Bachelor of Arts, Biochemistry Rutgers College, State University of New Jersey, USA - Academic societies
2020-01 -- 2020-12 American Society for Biochemistry and Molecular Biology 1997-01 -- 2020-12 ASM (American Society of Microbiology) 2017-04 -- (current) THE JAPANESE SOCIETY OF PARASITOLOGY 2007-01 -- 2020-03 RNA Society (International) 2017-04 -- (current) THE RNA SOCIETY OF JAPAN - Honors & Awards
2024-03 Deans Award, Medicine and Medical Sciences - Articles
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
Ignatochkina Anna V; Iguchi Jesavel A; Kore Anilkumar ...
Nucleic Acids Research/Epub, 2024-07 - Factors Affecting Undergraduate Medical Science Students’ Motivation to Study during the COVID-19 Pandemic
Mayers Thomas David; Mathis Bryan J.; Ho C. Kiong; Morika...
Education Sciences/12(9), 2022-09 - Editorial: mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation
Kiss L. Daniel; Vasudevan Deepika; Ho Kiong; Caliskan Neva
FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-06 - Genetic and functional analyses of archaeal ATP-dependent RNA ligase in C/D box sRNA circularization and ribosomal RNA processing
Liu Yancheng; Takagi Yuko; Sugijanto Milyadi; Nguyen Kie...
FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-03 - The impact of the COVID-19 pandemic on medical science students’ motivation to study: Preliminary findings
Mayers Thomas David; Mathis Bryan J; Ho Kiong; Morikawa ...
Journal of Medical English Education./20(3)/pp.52-55, 2021-10 - An essential surface motif (WAQKW) of yeast RNA triphosphatase mediates formation of the mRNA capping enzyme complex with RNA guanylyltransferase
Ho Kiong; Lehman Kevin; Shuman Stewart
Nucleic Acids Research/27(24)/pp.4671-4678, 1999-01 - Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills
Ho C. Kiong; Mayers Thomas David; Morikawa Kazuya; Watana...
Journal of Medical English Education/20(3)/pp.39-46, 2021-10 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas; Morikawa Kazuya; Fukuda Aya; Watanabe Yuk...
J Med Eng Educ/19(1)/pp.40-44, 2020-02 - Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5' end of the RNA substrate
Takagi Yuko; Kuwabara Naoyuki; Dang Truong Tat; Furukawa ...
Journal of Biological Chemistry/295(27)/pp.9076-9086, 2020-05 - Mutational Analyses of Yeast RNA Triphosphatases Highlight a Common Mechanism of Metal-dependent NTP Hydrolysis and a Means of Targeting Enzymes to Pre-mRNAs in Vivo by Fusion to the Guanylyltransferase Component of the Capping Apparatus
Pei Yi; Ho Kiong; Schwer Beate; Shuman Stewart
Journal of Biological Chemistry/274(41)/pp.28865-28874, 1999-10 - An international exchange program for undergraduate medical science students.
Mayers Thomas; Morikawa Kazuya; Ho Kiong; Ohneda Osamu
J Med Eng Educ/17(1)/pp.7-13, 2018-04 - Cleavage of 3'-terminal adenosine by archaeal ATP-dependent RNA ligase
Yoshinari Shigeo; Liu Yancheng; Gollnick Paul; Ho C Kiong
Scientific reports/7(1), 2017-09 - Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis
Gu H; Yoshionari S; Ghosh R; Ignatochkina AV; Gollnick PD; Mur...
Nucleic acids research/44(5)/pp.2337-2347, 2016-03 - Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase
Paul Smith; Ho Kiong; Yuko Takagi; Hakim Djaballah; Stewart S...
mBIO/7(1)/p.10.1128/mBio.00058-16, 2016-02 - Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
Ho Kiong
The Journal of Medical English Education/14(3)/pp.93-98, 2015-10 - The messenger RNA decapping and recapping pathway in Trypanosoma
Ignatochkina AV; Takagi Y; Liu Y; Negate K; Ho Kiong
Proceedings of the National Academy of Sciences USA/112(22)/pp.6967-6972, 2015-06 - Archaea RNA Ligase is a Homodimeric Protein that Catalyzes Intramolecular Ligation of Single-Stranded RNA and DNA.
Torchea C Takagi Y and Ho CK.
Nucleic Acid Research/36/p.6218-6227, 2008-01 - Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events.
Dong H; Ray D; Ren S; Zhang B; Puig-Basagoiti F; Takagi ...
J. Virol./81/p.4412-4421, 2007-01 - Trypanosoma brucei Encodes a Bifunctional Capping Enzyme Essential for Cap 4 Formation on the Spliced Leader RNA.
Takagi Y Sindkar S Ekonomidis D Hall MP and Ho CK.
J. Biol. Chem/282/p.15995-16005, 2007-01 - Characterization of a Trypanosoma brucei mRNA Cap (Guanine N-7) Methyltransferase.
Hall MP and Ho CK.
RNA/12/p.488 -497, 2006-01 - Functional Characterization of a 48-kDa Trypanosoma brucei Cap 2 RNA Methyltransferase.
Hall MP and Ho CK.
Nucleic Acid Research/34/p.5594 - 5602, 2006-01 - Identification of the MicroRNAs of the Herpesvirus Family.
Pfeffer S Sewer A Lagos-Quintana M Sheridan R Sander...
Nature Method/2/p.269-276, 2005-01 - Structure and Mechanism of RNA Ligase.
Ho CK Wang LK Lima CD and Shuman S.
Structure/12/p.327-339, 2004-01 - Portability and Fidelity of RNA Repair Systems.
Schwer B; Sawaya R; Ho CK; Shuman S.; +HO KIONG
Proc. Natl. Acad. Sci. USA/101/p.2788-2793, 2004-01 - Characterization of Bacteriophage KVP40 and T4 RNA Ligase 2.
Yin S Ho CK Miller ES and Shuman S.
Virology/319/p.141-151, 2004-01 - more...
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
- Books
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
Ho Kiong
Methods Molecular Biology/Humana Press, New York, NY/pp.1-9, 2017-08
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
- Conference, etc.
- Identification of Cytoplasmic mRNA Capping Targets in Trypanosoma cruzi
HO Kiong
第93回日本寄生虫学会大会/2024-03-09--2024-03-10 - Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
HO Kiong; Ignatochikina Anna; Akichika Shinichiro; Suz...
24th Annual meeting of RNA Society Japan/2023-07-03--2023-07-05 - The Analysis of Uncapped mRNA Transcriptome in Trypanosoma Parasites
Nguyen Kieu DM; Takagi Yuko; HO Kiong
24th Annual Meeting of the RNA Society of Japan/2023-07-05--2023-07-07 - University of Tsukuba Joint Symposium in Biomedical Science
Ho Kiong
The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18 - The Identification and Characterization of RNA Recapping Targets in Trypanosomes
Ho Kiong
The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18 - Unique Cap-dependent RNA Methyltransferase activity in Trypanosoma brucei
Ho Kiong
The 23rd Annual Meeting of the RNA Society/2022-07-20--2022-07-22 - Circularization of C/D Box sRNA by Archaeal ATP-Dependent RNA Ligase.
Ho Kiong
23rd Annual RNA Meeting Japan/2022-07-20--2022-07-22 - Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
Ho Kiong
92nd Annual Meeting of the Japanese Society for Parasitology./2023-03-30--2023-03-31 - Medical science summer research program in the University of Tsukuba in the era of COVID-19
Mayers Thomas David; Ho C. Kiong
The 55th Annual Meeting of the Japan Society for Medical Education/2023-07-28--2023-07-29 - The impact of the COVID-19 pandemic on medical science students’ motivation to study
Mayers Thomas David; Mathis Bryan James; Ho C. Kiong; Mor...
24th JASMEE Academic Meeting/2021-07-17--2021-07-18 - Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
Ho Kiong; Anna Ignatochkina
3rd - Tsukuba Purification Forum/2021-02-19--2021-02-19 - Regulation of Protozoa Gene Expression by mRNA Recapping Pathway
Ho Kiong
The 2nd Joint Young Researcher Meeting in Biomedical Sciences/2020-01-10--2020-01-11 - Crystal structure of Trypanosoma RNA triphosphatase illuminates the mechanism of triphosphate and nucleic acid recognition.
Ho Kiong; Takagi Yuko; Kuwabara Naoyuki; Truong Dang; Fur...
The 42nd Annual Meeting of the Molecular Biology Society of Japan/2019-12-03--2019-12-06 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
The 22nd JASMEE Academic Meeting/2019-08-03--2019-08-04 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
The 22nd JASMEE Academic Meeting/2019-08-03--2019-08-04 - Targeting of mRNA Cap Formation for Treatment of Parasitic Infections
Ho Kiong
The Joint Symposium in Infectious Diseases/2019-02-22--2019-02-22 - Structural and Functional Analysis of protozoan mRNA capping enzyme
HO KIONG
20th RNA Meeting in Japan/2018-07-09--2018-07-12 - The messenger RNA recapping pathway in Trypanosome
Ho Kiong
88th Japan Parasitology Meeting/2019-03-14--2019-03-16 - Structural and Functional Analysis of Trypanosoma RNA Triphosphatase
HO KIONG
第88回日本寄生虫学会大会/2019-03-14--2019-03-16 - RNA methylation at the 5’-end of the mRNA stimulates Trypanosoma mRNA recapping activities
Ho Kiong
Cold Spring Harbor Meeting, Translational Control Meeting/2018-09-04--2018-09-08 - Structure and mechanism of archaeal ATP-dependent RNA ligase
Ho Kiong; Yoshinari Shigeo; Murakami Katsuhiko S.
Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17 - Messenger RNA recapping enzyme is regulated by hypermethylation at the 5’-end of the RNA
Ho Kiong; Ignatochkina Anna V.; Iguchi Jesavel; Kore Ani...
Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17 - Molecular Mechanism of mRNA Recapping in Trypanosome
HO KIONG
2017年度生命科学系学会合同年次大会/2017-12-06--2017-12-09 - Identification and characterization of a novel 5'-monophosphate RNA kinase in Trypanosoma brucei
Ho Kiong
21th Annual RNA Society Meeting/2016-06-28--2016-07-02 - Recapping the Message: The mRNA Decapping and Recapping Pathway in Trypanosomes
Ho Kiong
21th Annual RNA Society International Meeting/2016-06-28--2016-07-02 - more...
- Identification of Cytoplasmic mRNA Capping Targets in Trypanosoma cruzi
- Teaching
2024-10 -- 2025-02 Basic Experiments in Human Biology University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Human Biology I University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Human Biology II University of Tsukuba. 2024-10 -- 2025-02 Special Lectures in Human Biology II University of Tsukuba. 2024-10 -- 2025-02 Special Research in Human Biology II University of Tsukuba. 2024-04 -- 2024-08 Special Lectures in Human Biology I University of Tsukuba. 2024-04 -- 2024-08 Laboratory Training in Human Biology I University of Tsukuba. 2024-10 -- 2024-11 Invitation to Arts and Sciences University of Tsukuba. 2024-04 -- 2024-08 Infectious Diseases: Basic and Clinical Aspects University of Tsukuba. 2024-04 -- 2024-08 Lecture and Discussion in Human Medical Biology I University of Tsukuba. more... - Other educational activities
2023-08 -- 2023-08 Infection Diagnosis Workshop VNU International University (HCMC), Vietnam 2023-08 -- 2023-08 Undergraduate Medical Science Course in Tsukuba 筑波大学 2023-07 -- 2023-07 Summer Research Program Online 2023 筑波大学医学医療系 2023-10 -- 2023-10 Summer Research Program Plus 2023 筑波大学医学医療系 2021-06 -- 2023-06 Frontiers in Molecular Biosciences 2022-02 -- 2022-02 Infection Biology Workshop 2022-10 -- 2022-10 Summer Research Program Plus 2022 フロンティア医科学 2022-07 -- 2022-07 Summer Research Program Online 2022 2023-02 -- 2023-02 Undergraduate Medical Science Course in Tsukuba 2022-02 -- 2022-02 Medical Science Course in Tsukuba Online Univeristy of Tsukuba, Undergraduate Medical Science more... - Talks
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
Ho Kiong; Anna Ignatochkina
3rd Tsukuba Purification Forum/2021-02-19--2021-02-19 - Structure and Mechanism of RNA Repair Enzymes
Ho Kiong
生命と機能とかたち/2018-03-07--2018-03-07
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
- University Management
2018-04 -- (current) 全学 学群教育課程委員会 委員 2020-04 -- (current) 全学 国際交流支援室企画・審査委員会 委員 2020-04 -- (current) 全学 海外生教育プログラム等検討委員会 委員 2018-04 -- (current) 全学 国際戦略委員会 委員 2021-04 -- (current) 医学医療系 国際連携委員会 委員長 2021-04 -- (current) 医学医療系 企画委員会 委員 2019-04 -- (current) ヒューマンバイオロジープログラム 学位審査委員会 委員長 2014-04 -- (current) HBP Publicity Committee Member 2013-04 -- (current) HBP International Affairs Member 2020-04 -- (current) 医学学位プログラム 国際推進委員会 委員 more... - Other activities
2021-04 -- (current) Frontiers in Molecular Bioscience - Associate Editor
(Last updated: 2024-08-30)