HO Kiong(ホー キョン)
- 所属
- 医学医療系
- 職名
- 准教授
- URL
- eメール
- 564:923:N]Y8/W?>@6@-,W,.W5;d
- 研究分野
寄生虫学(含衛生動物学) 機能生物化学 分子生物学 - 研究キーワード
Parasitology, RNA Processing, RNA ligation, Trypanosoma - 研究課題
Structure and biological targets of Trypanosome mRNA recapping enzyme 2021 -- 2023 HO KIONG 日本学術振興会/基盤研究(C) 4,290,000円 Mechanism of mRNA recapping pathway in trypanosome 2016-04 -- 2020-03 HO Kiong 日本学術振興会/科研費/基盤研究(B) 17,290,000円 Structural, Functional and Genetic Analysis of Archaea RNA Ligase 2011-04 -- 2016-03 Kiong Ho アメリカ国立科学財団/Div Of Molecular and Cellular Bioscience 76,500,000円 Mechanism of mRNA cap formation in Trypanosoma brucei 2006-07 -- 2011-06 HO KIONG アメリカ心臓協会/Scientist Development Grant 26,000,000円 Mechanism of Archaeal RNA ligase 2007-07 -- 2008-09 HO KIONG University at Buffalo/UB2020 Interdisciplinary Research Development Fund 4,000,000円 - 職歴
2003-01 -- 2010-10 ニューヨーク州立大学、バッファロー校Department of Biological Sciences助教授 2000-01 -- 2003-10 スローンケタリンがん研究所Program in Molecular Biology主任研究員 1997-04 -- 1999-12 スローンケタリンがん研究所(米国)Program in Molecular BiologyPost-doctoral Fellow - 学歴
1986-09 -- 1990-01 米国ラトガース大学 ニュージャージー州立大学 College of Arts and Sciences 生物化学 1990-09 -- 1997-03 米国コーネル大学医科学大学院 分子生物 Ph.D. 分子生物 - 取得学位
1997-02 Ph.D. Molecular Biology 米国コーネル大学医科学大学院 1990-1 Bachelor of Arts, Biochemistry ラトガーズ、ニュージャージ州立大学 - 所属学協会
2020-01 -- 2020-12 American Society for Biochemistry and Molecular Biology 1997-01 -- 2020-12 ASM (American Society of Microbiology) 2017-04 -- (現在) 日本寄生虫学会 2007-01 -- 2020-03 RNA Society (International) 2017-04 -- (現在) 日本RNA学会 - 受賞
2024-03 医学学群長賞 - 論文
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
Ignatochkina Anna V; Iguchi Jesavel A; Kore Anilkumar ...
Nucleic Acids Research/Epub, 2024-07 - Factors Affecting Undergraduate Medical Science Students’ Motivation to Study during the COVID-19 Pandemic
Mayers Thomas David; Mathis Bryan J.; Ho C. Kiong; Morika...
Education Sciences/12(9), 2022-09 - Editorial: mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation
Kiss L. Daniel; Vasudevan Deepika; Ho Kiong; Caliskan Neva
FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-06 - Genetic and functional analyses of archaeal ATP-dependent RNA ligase in C/D box sRNA circularization and ribosomal RNA processing
Liu Yancheng; Takagi Yuko; Sugijanto Milyadi; Nguyen Kie...
FRONTIERS IN MOLECULAR BIOSCIENCES/9, 2022-03 - The impact of the COVID-19 pandemic on medical science students’ motivation to study: Preliminary findings
Mayers Thomas David; Mathis Bryan J; Ho Kiong; Morikawa ...
Journal of Medical English Education./20(3)/pp.52-55, 2021-10 - An essential surface motif (WAQKW) of yeast RNA triphosphatase mediates formation of the mRNA capping enzyme complex with RNA guanylyltransferase
Ho Kiong; Lehman Kevin; Shuman Stewart
Nucleic Acids Research/27(24)/pp.4671-4678, 1999-01 - Advanced Topics in Biotechnology and Medicine: An intensive literature-based course to encourage critical thinking in science and build academic English skills
Ho C. Kiong; Mayers Thomas David; Morikawa Kazuya; Watana...
Journal of Medical English Education/20(3)/pp.39-46, 2021-10 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas; Morikawa Kazuya; Fukuda Aya; Watanabe Yuk...
J Med Eng Educ/19(1)/pp.40-44, 2020-02 - Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5' end of the RNA substrate
Takagi Yuko; Kuwabara Naoyuki; Dang Truong Tat; Furukawa ...
Journal of Biological Chemistry/295(27)/pp.9076-9086, 2020-05 - Mutational Analyses of Yeast RNA Triphosphatases Highlight a Common Mechanism of Metal-dependent NTP Hydrolysis and a Means of Targeting Enzymes to Pre-mRNAs in Vivo by Fusion to the Guanylyltransferase Component of the Capping Apparatus
Pei Yi; Ho Kiong; Schwer Beate; Shuman Stewart
Journal of Biological Chemistry/274(41)/pp.28865-28874, 1999-10 - An international exchange program for undergraduate medical science students.
Mayers Thomas; Morikawa Kazuya; Ho Kiong; Ohneda Osamu
J Med Eng Educ/17(1)/pp.7-13, 2018-04 - Cleavage of 3'-terminal adenosine by archaeal ATP-dependent RNA ligase
Yoshinari Shigeo; Liu Yancheng; Gollnick Paul; Ho C Kiong
Scientific reports/7(1), 2017-09 - Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis
Gu H; Yoshionari S; Ghosh R; Ignatochkina AV; Gollnick PD; Mur...
Nucleic acids research/44(5)/pp.2337-2347, 2016-03 - Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase
Paul Smith; Ho Kiong; Yuko Takagi; Hakim Djaballah; Stewart S...
mBIO/7(1)/p.10.1128/mBio.00058-16, 2016-02 - Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
Ho Kiong
The Journal of Medical English Education/14(3)/pp.93-98, 2015-10 - The messenger RNA decapping and recapping pathway in Trypanosoma
Ignatochkina AV; Takagi Y; Liu Y; Negate K; Ho Kiong
Proceedings of the National Academy of Sciences USA/112(22)/pp.6967-6972, 2015-06 - Archaea RNA Ligase is a Homodimeric Protein that Catalyzes Intramolecular Ligation of Single-Stranded RNA and DNA.
Torchea C Takagi Y and Ho CK.
Nucleic Acid Research/36/p.6218-6227, 2008-01 - Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events.
Dong H; Ray D; Ren S; Zhang B; Puig-Basagoiti F; Takagi ...
J. Virol./81/p.4412-4421, 2007-01 - Trypanosoma brucei Encodes a Bifunctional Capping Enzyme Essential for Cap 4 Formation on the Spliced Leader RNA.
Takagi Y Sindkar S Ekonomidis D Hall MP and Ho CK.
J. Biol. Chem/282/p.15995-16005, 2007-01 - Characterization of a Trypanosoma brucei mRNA Cap (Guanine N-7) Methyltransferase.
Hall MP and Ho CK.
RNA/12/p.488 -497, 2006-01 - Functional Characterization of a 48-kDa Trypanosoma brucei Cap 2 RNA Methyltransferase.
Hall MP and Ho CK.
Nucleic Acid Research/34/p.5594 - 5602, 2006-01 - Identification of the MicroRNAs of the Herpesvirus Family.
Pfeffer S Sewer A Lagos-Quintana M Sheridan R Sander...
Nature Method/2/p.269-276, 2005-01 - Structure and Mechanism of RNA Ligase.
Ho CK Wang LK Lima CD and Shuman S.
Structure/12/p.327-339, 2004-01 - Portability and Fidelity of RNA Repair Systems.
Schwer B; Sawaya R; Ho CK; Shuman S.; +HO KIONG
Proc. Natl. Acad. Sci. USA/101/p.2788-2793, 2004-01 - Characterization of Bacteriophage KVP40 and T4 RNA Ligase 2.
Yin S Ho CK Miller ES and Shuman S.
Virology/319/p.141-151, 2004-01 - さらに表示...
- Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
- 著書
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
Ho Kiong
Methods Molecular Biology/Humana Press, New York, NY/pp.1-9, 2017-08
- Detection and Identification of Uncapped RNA by Ligation-Mediated Reverse Transcription Polymerase Chain Reaction
- 会議発表等
- Identification of Cytoplasmic mRNA Capping Targets in Trypanosoma cruzi
HO Kiong
第93回日本寄生虫学会大会/2024-03-09--2024-03-10 - Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
HO Kiong; Ignatochikina Anna; Akichika Shinichiro; Suz...
第24回日本RNA学会/2023-07-03--2023-07-05 - The Analysis of Uncapped mRNA Transcriptome in Trypanosoma Parasites
Nguyen Kieu DM; Takagi Yuko; HO Kiong
第24回日本RNA学会年会/2023-07-05--2023-07-07 - University of Tsukuba Joint Symposium in Biomedical Science
Ho Kiong
The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18 - The Identification and Characterization of RNA Recapping Targets in Trypanosomes
Ho Kiong
The 3rd University of Science – University of Tsukuba Joint Symposium in Biomedical Science/2023-02-18--2023-02-18 - Unique Cap-dependent RNA Methyltransferase activity in Trypanosoma brucei
Ho Kiong
第23回日本RNA学会年会/2022-07-20--2022-07-22 - Circularization of C/D Box sRNA by Archaeal ATP-Dependent RNA Ligase.
Ho Kiong
第23回日本RNA学会年会/2022-07-20--2022-07-22 - Modification Beyond the Hypermethylated Cap 4 Structure in Trypanosoma Spliced Leader RNA
Ho Kiong
第92回日本寄生虫学会大会/2023-03-30--2023-03-31 - Medical science summer research program in the University of Tsukuba in the era of COVID-19
Mayers Thomas David; Ho C. Kiong
第 55 回日本医学教育学会大会/2023-07-28--2023-07-29 - The impact of the COVID-19 pandemic on medical science students’ motivation to study
Mayers Thomas David; Mathis Bryan James; Ho C. Kiong; Mor...
日本医学英語教育学会学術集会/2021-07-17--2021-07-18 - Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
Ho Kiong; Anna Ignatochkina
第3回つくば精製フォーラム/2021-02-19--2021-02-19 - Regulation of Protozoa Gene Expression by mRNA Recapping Pathway
Ho Kiong
The 2nd Joint Young Researcher Meeting in Biomedical Sciences/2020-01-10--2020-01-11 - トリパノソーマRNA triphosphataseの結晶構造解析による三リン酸ならびに核酸認識機構の解明
Ho Kiong; Takagi Yuko; Kuwabara Naoyuki; Truong Dang; Fur...
第42回日本分子生物学会/2019-12-03--2019-12-06 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
第22回日本医学英語教育学会学術集会/2019-08-03--2019-08-04 - Involving high school students in medical science exchange programs: Experiences from the University of Tsukuba
Mayers Thomas David; Ho Kiong; Fukuda Aya; Watanabe Yuki...
第22回日本医学英語教育学会学術集会/2019-08-03--2019-08-04 - Targeting of mRNA Cap Formation for Treatment of Parasitic Infections
Ho Kiong
The Joint Symposium in Infectious Diseases/2019-02-22--2019-02-22 - Structural and Functional Analysis of protozoan mRNA capping enzyme
HO KIONG
第20回日本RNA学会年会/2018-07-09--2018-07-12 - The messenger RNA recapping pathway in Trypanosome
Ho Kiong
第88回日本寄生虫学会大会/2019-03-14--2019-03-16 - Structural and Functional Analysis of Trypanosoma RNA Triphosphatase
HO KIONG
第88回日本寄生虫学会大会/2019-03-14--2019-03-16 - RNA methylation at the 5’-end of the mRNA stimulates Trypanosoma mRNA recapping activities
Ho Kiong
Cold Spring Harbor Meeting, Translational Control Meeting/2018-09-04--2018-09-08 - Structure and mechanism of archaeal ATP-dependent RNA ligase
Ho Kiong; Yoshinari Shigeo; Murakami Katsuhiko S.
Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17 - Messenger RNA recapping enzyme is regulated by hypermethylation at the 5’-end of the RNA
Ho Kiong; Ignatochkina Anna V.; Iguchi Jesavel; Kore Ani...
Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17 - Molecular Mechanism of mRNA Recapping in Trypanosome
HO KIONG
2017年度生命科学系学会合同年次大会/2017-12-06--2017-12-09 - Identification and characterization of a novel 5'-monophosphate RNA kinase in Trypanosoma brucei
Ho Kiong
21th Annual RNA Society Meeting/2016-06-28--2016-07-02 - Recapping the Message: The mRNA Decapping and Recapping Pathway in Trypanosomes
Ho Kiong
21th Annual RNA Society International Meeting/2016-06-28--2016-07-02 - さらに表示...
- Identification of Cytoplasmic mRNA Capping Targets in Trypanosoma cruzi
- 担当授業科目
2024-10 -- 2025-02 ヒューマンバイオロジー基礎実験 筑波大学 2024-04 -- 2024-08 ヒューマンバイオロジー演習I 筑波大学 2024-10 -- 2025-02 ヒューマンバイオロジー演習II 筑波大学 2024-10 -- 2025-02 ヒューマンバイオロジー特論II 筑波大学 2024-10 -- 2025-02 ヒューマンバイオロジー実験実習II 筑波大学 2024-04 -- 2024-08 ヒューマンバイオロジー特論I 筑波大学 2024-04 -- 2024-08 ヒューマンバイオロジー研究室演習I 筑波大学 2024-10 -- 2024-11 Invitation to Arts and Sciences 筑波大学 2024-04 -- 2024-08 感染症と基礎と臨床 筑波大学 2024-04 -- 2024-08 システム統御医学特論I 筑波大学 さらに表示... - 授業以外の教育活動
2023-08 -- 2023-08 感染生物ワークショップ VNU International University (HCMC), Vietnam 2023-08 -- 2023-08 Undergraduate Medical Science Course in Tsukuba 筑波大学 2023-07 -- 2023-07 Summer Research Program Online 2023 筑波大学医学医療系 2023-10 -- 2023-10 Summer Research Program Plus 2023 筑波大学医学医療系 2021-06 -- 2023-06 Frontiers in Molecular Biosciences 2022-02 -- 2022-02 感染生物ワークショップ 2022-10 -- 2022-10 Summer Research Program Plus 2022 フロンティア医科学 2022-07 -- 2022-07 Summer Research Program Online 2022 2023-02 -- 2023-02 Undergraduate Medical Science Course in Tsukuba 2022-02 -- 2022-02 Medical Science Course in Tsukuba Online 医療科学 さらに表示... - 一般講演
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
Ho Kiong; Anna Ignatochkina
第3回つくば精製フォーラム/2021-02-19--2021-02-19 - Structure and Mechanism of RNA Repair Enzymes
Ho Kiong
生命と機能とかたち/2018-03-07--2018-03-07
- Purification of a Putative Cap-dependent RNA Methyltransferase in Trypanosoma brucei
- 学内管理運営業績
2018-04 -- (現在) 全学 学群教育課程委員会 委員 2020-04 -- (現在) 全学 国際交流支援室企画・審査委員会 委員 2020-04 -- (現在) 全学 海外生教育プログラム等検討委員会 委員 2018-04 -- (現在) 全学 国際戦略委員会 委員 2021-04 -- (現在) 医学医療系 国際連携委員会 委員長 2021-04 -- (現在) 医学医療系 企画委員会 委員 2019-04 -- (現在) ヒューマンバイオロジープログラム 学位審査委員会 委員長 2014-04 -- (現在) ヒューマンバイオロジープログラム 広告委員会 委員 2013-04 -- (現在) ヒューマンバイオロジープログラム 国際連携委員会 委員 2020-04 -- (現在) 医学学位プログラム 国際推進委員会 委員 さらに表示... - その他の活動
2021-04 -- (現在) Frontiers in Molecular Bioscience - Associate Editor
(最終更新日: 2024-08-30)