TANI Kazutoshi
- Affiliation
- Center for Computational Sciences
- Official title
- Professor
- ORCID
- 0000-0003-4835-154X
- URL
- Research fields
Structural biochemistry - Research keywords
クライオ電子顕微鏡・膜タンパク質・光合成細菌 - Research projects
Electron crystallographic analysis of two dimensional crystals of membrane proteins maintaining proton gradient 2010-04 -- 2014-03 TANI Kazutoshi; FUJIYOSHI Yoshinori; ABE Kazuhiro Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B) 4,420,000Yen Structural and functional relationship of aqauporin-4 in brain 2014-04 -- 2017-03 Tani Kazutoshi; Fujiyoshi Yoshinori Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C) 4,940,000Yen Studies in structural physiology of channels 2015-05 -- 2020-03 FUJIYOSHI Yoshinori Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S) 180,050,000Yen Electron crystallographic analysis of tomographic volumes of 2D crystals of membrane proteins 2017-06 -- 2020-03 Tani Kazutoshi Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory) 6,240,000Yen 病原細菌エフェクターによるNF-κB経路を標的とした感染機構の解析 2020-04 -- 2024-03 水島 恒裕; 谷 一寿; Kim Minsoo 日本学術振興会/科学研究費助成事業 基盤研究(B) 17,680,000Yen Structural study of photo energy conversion system of light harvesting complex from photobacterium 2022-04 -- 2025-03 谷 一寿 Japan Society for the Promotion of Science/Grants-in-Aid for Scientific Research 4,030,000Yen 電子線トモグラフィーと結晶学を組み合わせた膜タンパク質の構造解析手法の確立 2017-06 -- (current) /科学研究費助成事業 0Yen クライオ電子顕微鏡を用いた膜タンパク質の高分解能動的構造解析と技術人材育成支援 2017-09 -- (current) 谷 一寿 日本医療研究開発機構(AMED)/創薬等ライフサイエンス研究支援基盤事業 0Yen - Career history
2012-04 -- 2015-03 Nagoya UniversityCellular and Structural Physiology Institute DivisionDesignated associate professor 2015-04 -- 2019-03 Nagoya UniversityCellular and Structural Physiology Institute DivisionDesignated professor 2019-04 -- 2023-11 Mie UniversityGraduate School of Medicine特任教授 2023-12 -- (current) University of TsukubaCenter for Computational SciencesProfessor - Academic background
1990-04 -- 1994-03 Tokyo Institute of Technology Faculty of Life Science and Engineering 生命理学科 1994-04 -- 1996-03 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering バイオサイエンス専攻 1996-04 -- 1999-08 The University of Tokyo Graduate School, Division of Science 生物化学 1996-04 -- 1999-08 東京大学 大学院理学系研究科 生物化学専攻 1994-04 -- 1996-03 東京工業大学 大学院生命工学研究科 バイオサイエンス専攻 1990-04 -- 1994-03 東京工業大学 生命理工学部 生命理学科 - Degree
1994-03 学士（理学） 東京工業大学 1996-03 修士（理学） 東京工業大学 2007-09 Ph.D. Nagoya University - Academic societies
-- (current) 日本生物物理学会 -- (current) 日本顕微鏡学会 -- (current) 日本分子生物学会 -- (current) 日本蛋白質科学会 - Articles
- High-resolution structure and biochemical properties of the LH1–RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum
Tani Kazutoshi; Kanno Ryo; Harada Ayaka; Kobayashi Yu...
Communications Biology/7(1), 2024-02-12 - Rhodobacter capsulatus forms a compact crescent-shaped LH1-RC photocomplex.
Tani Kazutoshi; Kanno Ryo; Ji Xuan-Cheng; Satoh Itsus...
Nature communications/14(1)/pp.846-846, 2023-02-15 - Advances in the Spectroscopic and Structural Characterization of Core Light-Harvesting Complexes from Purple Phototrophic Bacteria
Kimura Yukihiro; Tani Kazutoshi; Madigan Michael T; Wa...
The Journal of Physical Chemistry B, 2023-01-03 - An LH1–RC photocomplex from an extremophilic phototroph provides insight into origins of two photosynthesis proteins
Tani Kazutoshi; Kanno Ryo; Kurosawa Keigo; Takaichi S...
Communications Biology/5(1), 2022-11-07 - A Ca2+-binding motif underlies the unusual properties of certain photosynthetic bacterial core light-harvesting complexes.
Tani Kazutoshi; Kobayashi Kazumi; Hosogi Naoki; Ji Xu...
The Journal of biological chemistry/298(6)/pp.101967-101967, 2022-04-20 - Asymmetric structure of the native Rhodobacter sphaeroides dimeric LH1-RC complex.
Tani Kazutoshi; Kanno Ryo; Kikuchi Riku; Kawamura Sak...
Nature communications/13(1)/pp.1904-1904, 2022-04-07 - Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Kuzuya Maki; Hirano Hidemi; Hayashida Kenichi; Watanab...
Science signaling/15(720)/p.eabg6941, 2022-02-08 - A previously unrecognized membrane protein in the Rhodobacter sphaeroides LH1-RC photocomplex
Tani Kazutoshi; V. P. Nagashima Kenji; Kanno Ryo; Kawa...
Nature Communications/12(1)/p.6300, 2021-11 - Cryo-EM Structure of the Photosynthetic LH1-RC Complex from Rhodospirillum rubrum.
Tani Kazutoshi; Kanno Ryo; Ji Xuan-Cheng; Hall Malgor...
Biochemistry/62/pp.2483-2491, 2021-07-29 - Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
Hiragi Keito; Nishio Kazuya; Moriyama Shu; Hamaguchi ...
Journal of structural biology/213(3)/pp.107748-107748, 2021-05-24 - Leucine Dehydrogenase: Structure and Thermostability.
Yamaguchi Hiroki; Kamegawa Akiko; Nakata Kunio; Kashiw...
Sub-cellular biochemistry/96/pp.355-372, 2021 - Cryo-EM structure of a Ca2+-bound photosynthetic LH1-RC complex containing multiple αβ-polypeptides.
Tani Kazutoshi; Kanno Ryo; Makino Yuki; Hall Malgorza...
Nature communications/11(1)/pp.4955-4955, 2020-10-02 - Characterization of Critical Residues in the Extracellular and Transmembrane Domains of the Endothelin Type B Receptor for Propagation of the Endothelin-1 Signal.
Doi Tomoko; Kikuta Kohei; Tani Kazutoshi
Biochemistry/59(18)/pp.1718-1727, 2020-05-12 - Development of a deep learning-based method to identify “good” regions of a cryo-electron microscopy grid
Yokoyama Yuichi; Terada Tohru; Shimizu Kentaro; Nishik...
Biophysical Reviews/12/pp.349-354, 2020-03-11 - Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids
Burendei Batuujin; Shinozaki Ruriko; Watanabe Masakats...
Science Advances/6/p.eaax3157, 2020-02 - Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy
Yamaguchi Hiroki; Kamegawa Akiko; Nakata Kunio; Kashiw...
Journal of Structural Biology/205(1)/pp.11-21, 2019-01 - X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog
Shihoya Wataru; Nishizawa Tomohiro; Yamashita Keitaro; ...
NATURE STRUCTURAL & MOLECULAR BIOLOGY/24(9)/pp.758-+, 2017-09 - The cryo-EM structure of gastric H+, K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors
Abe Kazuhiro; Shimokawa Jun; Naito Mao; Munson Keith; ...
SCIENTIFIC REPORTS/7(1)/p.6632, 2017-07 - Crystal structures of claudins: insights into their intermolecular interactions
Suzuki Hiroshi; Tani Kazutoshi; Fujiyoshi Yoshinori
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES/1397(1)/pp.25-34, 2017-06 - Atomic structure of the innexin-6 gap junction channel determined by cryo-EM
Oshima Atsunori; Tani Kazutoshi; Fujiyoshi Yoshinori
NATURE COMMUNICATIONS/7/p.13681, 2016-12 - Activation mechanism of endothelin ETB receptor by endothelin-1
Shihoya Wataru; Nishizawa Tomohiro; Okuta Akiko; Tani ...
NATURE/537(7620)/pp.363-+, 2016-09 - Two-dimensional crystallization of monomeric bovine cytochrome c oxidase with bound cytochrome c in reconstituted lipid membranes
Osuda Yukiho; Shinzawa-Itoh Kyoko; Tani Kazutoshi; Mae...
MICROSCOPY/65(3)/pp.263-267, 2016-06 - Thermostabilization of the Human Endothelin Type B Receptor
Okuta Akiko; Tani Kazutoshi; Nishimura Shoko; Fujiyosh...
JOURNAL OF MOLECULAR BIOLOGY/428(11)/pp.2265-2274, 2016-06 - Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide
Kamegawa Akiko; Hiroaki Yoko; Tani Kazutoshi; Fujiyosh...
MICROSCOPY/65(2)/pp.177-184, 2016-04 - Hexadecameric structure of an invertebrate gap junction channel
Oshima Atsunori; Matsuzawa Tomohiro; Murata Kazuyoshi; ...
JOURNAL OF MOLECULAR BIOLOGY/428(6)/pp.1227-1236, 2016-03 - more...
- High-resolution structure and biochemical properties of the LH1–RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum
- Books
- STRUCTURE AND INHIBITOR OF WATER CHANNEL IN BRAIN
Tanimura Y.; 谷 一寿; Suzuki H.; Nishikawa K.; Kamegawa ...
Pan Stanford Publishing, 2011 - 現代生物科学入門 構造機能生物学・膜タンパク質構造機能生物学
藤吉 好則; 谷 一寿
岩波書店, 2011
- STRUCTURE AND INHIBITOR OF WATER CHANNEL IN BRAIN
- Conference, etc.
- ヌクレオソームリンカーDNAとH1存在下でのSSX2RD構造
渋谷 綾音; 堀越 直樹; 谷 一寿; 胡桃坂 仁志; 岩崎 憲治
2024年度TARAセミナー・生理研研究会/2024-10-29--2024-10-30 - High-resolution structural analysis of a membrane protein using a CRYO ARM300 II equipped with an omega filter.
原田 彩佳; 谷 一寿; 菅野 亮; 岩崎 憲治; 木村 行宏; 大友 征宇
第24回日本蛋白質科学会年会/2024-06-11--2024-06-13 - 分子動力学シミュレーションによるがん原因融合タンパク質SS18-SSXのC末端結合領域とヌクレオソームの相互作用解析
小淵 里恵; 段 炼; Kowit Hengphasatporn; 重田 育照; 谷 一寿; 鈴木 理...
第46回日本分子生物学会年会/2023-12-06--2023-12-08 - 天然変性タンパク質の部分構造解析
渋谷 綾音; 谷 一寿; 高橋 花南; 堀越 直樹; 宮ノ入 洋平; 吉永 匡希; 小淵 里恵; 原...
生理研研究会2023年度大会/2023-11-28--2023-11-29
- ヌクレオソームリンカーDNAとH1存在下でのSSX2RD構造
(Last updated: 2024-09-19)