髙山 真理子(タカヤマ マリコ)
- 所属
- 生命環境系
- 職名
- 助教
- 職歴
- 2019-10 -- (現在) - 筑波大学生命環境系助教 - 2019-04 -- 2019-09 - サナテックシード 株式会社技術部研究員 - 2015-10 -- 2019-03 - 筑波大学生命環境系常勤研究員 
- 学歴
- 2012-04 -- 2015-09 - 筑波大学 生命環境科学研究科 生物圏資源科学専攻 - 2010-04 -- 2012-03 - 筑波大学 生命環境科学研究科 生物資源科学専攻 - 2006-04 -- 2010-03 - 筑波大学 第二学群 生物資源学類 
- 取得学位
- 2015-09 - 博士(農学) - 筑波大学 
- 所属学協会
- 2010-05 -- (現在) - 日本植物細胞分子生物学会 
- 受賞
- 2021-09 - 日本植物バイオテクノロジー学会 特別賞 
- 論文
- Characterization of the Fruit Quality and Yield of a Genome-Edited High-GABA Tomato Cultivar (Solanum lycopersicum) Cultivated under Salt Stress Conditions
 Suzuki Toon; Takayama Mariko; Sumiyoshi Minako; Ezura ...
 ACS AGRICULTURAL SCIENCE & TECHNOLOGY, 2025-05-06
- CREATION OF TOMATOES WITH HIGH GABA ACCUMULATION BY GENE EDITING AND THEIR HYPOTENSIVE EFFECTS
 Minako Sumiyoshi; Yatabe Junichi; Ezura Hiroshi; Takay...
 JOURNAL OF HYPERTENSION/41(1)/pp.E407-E407, 2023-01
- Genetic improvement of tomato using gene editing technologies
 Nagamine Ai; Takayama Mariko; Ezura Hiroshi
 JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY/98(1)/pp.1-9, 2023-01
- Modification of tomato breeding traits and plant hormone signaling by target-AID, the genome-editing system inducing efficient nucleotide substitution
 Kashojiya Sachiko; Yu Lu; Takayama Mariko; Shirasawa ...
 Horticulture research/9, 2022-02
- Challenges and Prospects of New Plant Breeding Techniques for GABA Improvement in Crops: Tomato as an Example
 Gramazio Pietro; Takayama Mariko; Ezura Hiroshi
 FRONTIERS IN PLANT SCIENCE/11, 2020-09
- Accumulation mechanism of γ-aminobutyric acid in tomatoes (Solanum lycopersicum L.) under low O2 with and without CO2
 Mae Nobukazu; Makino Yoshio; Oshita Seiichi; Kawagoe Yos...
 Journal of agricultural and food chemistry/60(4)/pp.1013-1019, 2012-02
- Utilization of a Genome-Edited Tomato (Solanum lycopersicum) with High Gamma Aminobutyric Acid Content in Hybrid Breeding
 Lee Jeongeun; Nonaka Satoko; Takayama Mariko; Ezura Hiroshi
 Journal of agricultural and food chemistry/66(4)/pp.963-971, 2018-01
- Efficient increase of ɣ-aminobutyric acid (GABA) content in tomato fruits by targeted mutagenesis
 Nonaka Satoko; Arai Chikako; Takayama Mariko; Matsukura ...
 Scientific reports/7(1)/p.7057, 2017-08
- An Agrobacterium tumefaciens Strain with Gamma-Aminobutyric Acid Transaminase Activity Shows an Enhanced Genetic Transformation Ability in Plants
 Nonaka Satoko; Someya Tatsuhiko; Zhou Sha; Takayama Mari...
 SCIENTIFIC REPORTS/7, 2017-02
- Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
 Shimatani Zenpei; Kashojiya Sachiko; Takayama Mariko; Ter...
 Nature biotechnology/35(5)/p.441, 2017-03
- Activating glutamate decarboxylase activity by removing the autoinhibitory domain leads to hyper gamma-aminobutyric acid (GABA) accumulation in tomato fruit
 Takayama Mariko; Matsukura Chiaki; Ariizumi Tohru; Ezura ...
 PLANT CELL REPORTS/36(1)/pp.103-116, 2017-01
- How and why does tomato accumulate a large amount of GABA in the fruit?
 Takayama Mariko; Ezura Hiroshi
 FRONTIERS IN PLANT SCIENCE/6, 2015-08
- Tomato Glutamate Decarboxylase Genes SlGAD2 and SlGAD3 Play Key Roles in Regulating γ-Aminobutyric Acid Levels in Tomato (Solanum lycopersicum)
 Takayama Mariko; Koike Satoshi; Kusano Miyako; Matsukura ...
 Plant Cell Physiology/56(8)/pp.1533-1545, 2015-08
- An E8 promoter-HSP terminator cassette promotes the high-level accumulation of recombinant protein predominantly in transgenic tomato fruits: a case study of miraculin.
 Kurokawa Natsuku; Hirai Tadayoshi; Takayama Mariko; Hiwas...
 Plant Cell Reports/32(4)/pp.529-536, 2013-04
- Suppression of gamma-aminobutyric acid (GABA) transaminases induces prominent GABA accumulation, dwarfism and infertility in the tomato (Solanum lycopersicum L.).
 Satoshi Koike; Matsukura Chiaki; Mariko Takayama; Erika ...
 PLANT AND CELL PHYSIOLOGY/54(5)/pp.793-807, 2013-05
 
- Characterization of the Fruit Quality and Yield of a Genome-Edited High-GABA Tomato Cultivar (Solanum lycopersicum) Cultivated under Salt Stress Conditions
- 会議発表等
- Development of dwarf, high-functionality, good-tasting tomato varieties through genome editing for cultivation on the lunar farm
 Kuya Noriyuki; Katsuyama Hiroaki; Naoi Takashi; Takaya...
 Plant and Animal Genome Conference/2025-01-10--2025-01-15
- Characterization of a genome-edited high-GABA tomato (Solanum lycopersicum) for fruit quality and yield under salt stress cultivation
 Suzuki Toon; Takayama Mariko; Sumiyoshi Minako; Ezura ...
 XIX International Solanaceae Conference/2024-11-25--2024-11-28
- Can interdisciplinary fusion of fundamental researches open up the future of food sustainability?
 Shohei Nosaki; Shingo Sakamoto; Hideki Yoshida; Peng ...
 TSUKUBA CONFERENCE 2023/2023-09-26--2023-09-28
- CREATION OF TOMATOES WITH HIGH GABA ACCUMULATION BY GENE EDITING AND THEIR HYPOTENSIVE EFFECTS
 Minako Sumiyoshi; Yatabe Junichi; Ezura Hiroshi; Takay...
 29th Scientific Meeting of the International Society of Hypertension (ISH)/2022-10-12--2022-10-16
- ゲノム編集技術により作出したGABA高蓄積トマトの果実品質評価
 髙山 真理子; 住吉 美奈子; 水戸 千穂; 長谷川 繁弥; 高桑 優子; 江面浩
 第38回日本植物バイオテクノロジー学会(つくば)大会/2021-09-09--2021-09-11
- Molecular mechanism regulating GABA accumulation in tomato fruits
 Takayama Mariko; Koike Satoshi; Matsukura Chiaki; Ezura ...
 JAPANESE SOLANACEAE GENOMICS INITIATIVE (JSOL) 10TH INTERNATIONAL SYMPOSIUM ON SOLANACEAE GENOMICS/2013-11-29--2013-11-30
- Contribution of glutamate decarboxylase gene homologs on GABA biosynthesis in tomato fruits
 Takayama Mariko; Koike Satoshi; Matsukura Chiaki; Ezura ...
 International Symposium on Diversifying Biological Resources ~Toward Food Security and Sustainable Society~/2013-11-20--2013-11-21
- SlGAD2 and SlGAD3 are the key genes regulating GABA accumulation in tomato fruits
 Takayama Mariko; Koike Satoshi; Kusano Miyako; Nakabayash...
 Tsukuba Global Science Week 2013/2013-10-02--2013-10-04
- Effects of SlGAD gene regulation on GABA biosynthesis in tomato fruits
 Takayama Mariko; Koike Satoshi; Matsukura Chiaki; Ezura ...
 15th International Conference of FFC/2014-05-10--2014-05-11
- 高日持ち性トマトの作出に向けた新規ゲノム編集技術の適用
 髙山 真理子; 小松拓樹; 有泉亨; 西田敬二; 近藤昭彦; 江面浩
 第35回日本植物細胞分子生物学会/2017-08-29--2017-08-31
- GABA低蓄積トマトのメタボローム解析
 髙山 真理子; 平井正良; 草野都; 及川彰; 中林亮; 福島敦史; 斉藤和季; 江面浩
 第30回日本植物細胞分子生物学会/2012-08-03--2012-08-05
- 遺伝子組換えによるトマト果実におけるGABA濃度の制御
 髙山 真理子; 小池悟志; Azzi Lamia; 松倉千昭; 江面浩
 第29回日本植物細胞分子生物学会/2011-09-06--2011-09-08
- トマト果実におけるGAD遺伝子の発現制御がGABA含量に及ぼす影響
 髙山 真理子; 小池悟志; Azzi Lamia; 松倉千昭; 江面浩
 第28回日本植物細胞分子生物学会/2010-09-02--2010-09-03
 
- Development of dwarf, high-functionality, good-tasting tomato varieties through genome editing for cultivation on the lunar farm
- 担当授業科目
- 2025-04 -- 2025-08 - 農林生物学特別研究IS - 筑波大学 - 2025-04 -- 2025-08 - 農林生物学特別研究IIS - 筑波大学 - 2025-04 -- 2025-08 - 農林生物学特別研究IIF(春) - 筑波大学 - 2025-10 -- 2026-02 - 農林生物学特別研究IIF - 筑波大学 - 2025-10 -- 2026-02 - 農林生物学特別研究IF - 筑波大学 - 2025-04 -- 2025-08 - 農林生物学演習IS - 筑波大学 - 2025-04 -- 2025-08 - 農林生物学演習IIS - 筑波大学 - 2025-04 -- 2025-08 - 農林生物学演習IIF(春) - 筑波大学 - 2025-10 -- 2026-02 - 農林生物学演習IIF - 筑波大学 - 2025-10 -- 2026-02 - 農林生物学演習IF - 筑波大学 - さらに表示... 
(最終更新日: 2025-08-20)