坂本 竜弘(サカモト タツヒロ)

所属

医学医療系

職名

講師

研究課題

急性骨髄性白血病において非腫瘍細胞が果たす役割の解明	2021 -- 2023	坂本 竜弘	日本学術振興会/若手研究	4,550,000円

取得学位

2007-03	学士（医学）	筑波大学
2017-03	博士(医学)	筑波大学

論文

• Impact of CD34 positive cell dose in donor graft on the outcomes after haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide - A retrospective single-center study with a Japanese cohort
  Maruyama Yumiko; Nishikii Hidekazu; Kurita Naoki; Saka...
  Blood cells, molecules & diseases/105, 2023-12-30
  
  PubMed
• 同種造血幹細胞移植により長期寛解を得たCLEC16A::IL2融合遺伝子を有するT細胞前リンパ球性白血病
  百瀬 春佳; 栗田 尚樹; 錦井 秀和; 遊佐 希; 横山 和明; 清水 英吾; 井元 清哉; 南木...
  臨床血液/65(1)/pp.35-40, 2024-01
  
  PubMed
• Female and preserved platelet count subgroups of myelodysplastic syndrome patients benefit from standard-dose azacitidine
  Ogawa Shinichi; Sakamoto Tatsuhiro; Matsuoka Ryota; Is...
  CANCER REPORTS/Epub, 2023-11-28
• Tumor heterogeneity and immune-evasive T follicular cell lymphoma phenotypes at single-cell resolution
  Suma Sakurako; Suehara Yasuhito; Fujisawa Manabu; Abe ...
  LEUKEMIA/38(2)/pp.340-350, 2023-11-27
• Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group
  Sato Atsushi; Hatta Yoshihiro; Imai Chihaya; Oshima K...
  LANCET HAEMATOLOGY/10(6)/pp.419-432, 2023-05
• Safety of romiplostim administered immediately after cord-blood transplantation: a phase 1 trial
  Kurita Naoki; Nishikii Hidekazu; Maruyama Yumiko; Sueh...
  ANNALS OF HEMATOLOGY/102(10)/pp.2895-2902, 2023-08-17
  
  PubMed
• Repeated immunosuppressive rabbit antithymocyte globulin therapy for adult patients with relapsed or refractory aplastic anemia
  Sakamoto Tatsuhiro; Obara Naoshi; Maruyama Yumiko; Kat...
  EUROPEAN JOURNAL OF HAEMATOLOGY/111(5)/pp.768-776, 2023-08-07
  
  PubMed
• Tumor Necrosis Factor from Leukemic Microenvironment Provides Non-Leukemic Hematopoietic Stem Cells with Megakaryocyte Lineage Bias
  Nishikii Hidekazu; Saito Mizuki; Kimura Takaharu; Kiyo...
  BLOOD/140(1)/pp.5774-5775, 2022-11
• Elongation of Long-Chain Fatty Acids Is Crucial for Hematopoietic Stem Cell Engraftment and Leukemia Propagation
  Kato Takayasu; Kiyoki Yusuke; Kito Sakura; Matsuzaka ...
  BLOOD/140(1), 2022-11
• Risk Stratified Therapy with Nelarabine and Intensified Administration of L-Asparaginase for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia in Adolescents and Young Adults (JPLSG T-11/JALSG T-ALL-211-U): An Intergroup Phase 2 Study
  Hatta Yoshihiro; Sato Atsushi; Kada Akiko; Saito Akik...
  BLOOD/140(1), 2022-11
• Impact of Nelarabine, Intensive L-Asparaginase, and Protracted Intrathecal Therapy on Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group and the Japan Adult Leukemia Study Group
  Sato Atsushi; Hatta Yoshihiro; Imai Chihaya; Oshima K...
  BLOOD/138(1), 2021-11
• A Single-Cell Atlas of Nonhematopoietic Cells in Human Lymph Node and Lymphoma Reveals Landscape of Stromal Remodeling
  Abe Yoshiaki; Sakata-Yanagimoto Mamiko; Fujisawa Manabu; ...
  BLOOD/138(1), 2021-11
• NUP98::DDX10融合遺伝子を有した急性骨髄性白血病
  Kurita Naoki; Kato Takayasu; Nanmoku Toru; Maruyama Yumi...
  臨床血液/63(10)/pp.1397-1401, 2022-10
  
  PubMed
• The fatty acid elongase Elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation
  Kiyoki Yusuke; Kato Takayasu; Kito Sakura; Matsuzaka ...
  LEUKEMIA/37(4)/pp.910-913, 2023-03-08
  
  PubMed
• Novel translocation of POGZ/STK11 in de novo mast cell leukemia with KIT D816H mutation
  Ishitsuka Kantaro; Yoshizawa Yuki; Nishikii Hidekazu; Kus...
  LEUKEMIA & LYMPHOMA/63(14)/pp.3475-3479, 2022-09
  
  PubMed
• 高度な骨髄線維化を認めたリンパ形質細胞性リンパ腫
  Takarada Ayako; Momose Haruka; Kurita Naoki; Matsuoka Ry...
  臨床血液/64(1)/pp.54-59, 2023-01
  
  PubMed
• 免疫抑制療法後にASXL1変異クローンで造血が回復した重症再生不良性貧血
  Shimizu Yumoe; Nishikii Hidekazu; Iitsuka Tadashi; Matsuo...
  臨床血液/64(1)/pp.49-53, 2023-01
  
  PubMed
• 神経浸潤による末梢神経障害を合併した原発性マクログロブリン血症
  Norioka Natsuki; Kurita Naoki; Kamura Yuya; Sakamoto Tat...
  臨床血液/64(1)/pp.18-22, 2023-01
  
  PubMed
• Tet2-deficent inflammatory cells exacerbates lung cancer progression through promoting tumor angiogenesis
  Nguyentm Yen; Fujisawa Manabu; Nguyen Tran B.; Suehara Y...
  CANCER SCIENCE/113(1:SI), 2022-02
• Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuria
  Kamura Yuya; Sakamoto Tatsuhiro; Yokoyama Yasuhisa; Nishi...
  INTERNATIONAL JOURNAL OF HEMATOLOGY/116(1:SI)/pp.55-59, 2022-06
• Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations
  Tsuboi Yuri; Sakamoto Tatsuhiro; Makishima Kenichi; Su...
  Internal medicine (Tokyo, Japan)/62(10)/pp.1527-1530, 2022-09-13
  
  PubMed
• Administration of brentuximab vedotin to a Hodgkin lymphoma patient with liver dysfunction due to vanishing bile duct syndrome resulting in a partial response without any severe adverse events
  Ishitsuka Kantaro; Yokoyama Yasuhisa; Baba Naoko; Matsuok...
  JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY/62(3)/pp.154-157, 2022-07-12
  
  PubMed
• Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion
  Tsuboi Yuri; Iimura Yumoe; Matsumura Fumiaki; Nanmoku ...
  INTERNAL MEDICINE/62(4)/pp.595-600, 2022-06-21
  
  PubMed
• A Case of Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion
  Tsuboi Yuri; Iimura Yumoe; Matsumura Fumiaki; Nanmoku To...
  Internal medicine (Tokyo, Japan), 2022-06-21
  
  PubMed
• Salvage Cord Blood Transplantation Using a Short-term Reduced-intensity Conditioning Regimen for Graft Failure.
  Suma S; Yokoyama Y; Momose H; Makishima K; Kiyoki Y; ...
  INTERNAL MEDICINE/61(11)/pp.1673-1679, 2021-11
• さらに表示...

著書

• Animal Models of T-cell Lymphoma
  Hattori Keiichiro; Shrestha Raksha; Sakamoto Tatsuhiro...
  The Peripheral T‐Cell Lymphomas/John Wiley & Sons Ltd./pp.47-55, 2021-04
• Animal Models of T-cell Lymphoma
  Keiichiro Hattori Raksha Shrestha Tatsuhiro Sakamoto Man...
  The Peripheral T-Cell Lymphomas/John Wiley & Sons Ltd., 2021-02

会議発表等

• 茨城県における Tisagenlecleucel での治療状況に関する検討
  樽井 裕太朗; 錦井 秀和; 栗田 尚樹; 丸山 ゆみ子; 小川 晋一; 清水 誠一; 渡邉 真威; ...
  第46回日本造血･免疫細胞療法学会　総会/2024-03-21--2024-03-23
• 骨髄線維症に対する、移植後シクロフォスファミドを用いた HLA 半合致移植
  宮越敏宏; 栗田 尚樹; 丸山 ゆみ子; 小田 卓也; 海江田 拓実; 樽井 裕太朗; 松村 文明; ...
  第46回日本造血･免疫細胞療法学会　総会/2024-03-21--2024-03-23
• カルフィルゾミブ長期投与後に血栓性微小血管障害をきたした 1 例
  小田 卓弥; 横山 泰久; 海江田 拓実; 宮越 俊宏; 樽井 裕太朗; 松村 文明; 清木 祐介; ...
  第20回 日本血液学会関東甲信越地方会/2024-03-09--2024-03-09
• 単一細胞解像度での T 濾胞ヘルパー細胞リンパ腫の腫瘍細胞不均一性と腫瘍進化の解明
  須摩 桜子; 末原 泰人; 藤澤 学; 安部 佳亮; 槇島 健一; 坂本 竜弘; 千葉 滋; 坂田（...
  第28回 造血器腫瘍研究会/2024-01-26--2024-01-27
• Elucidating The Roles Of Immune Cells Arising From Clonal Hematopoiesis In Colon Cancer Metastasis
  Thi Ai Nhan Le; Nguyen Tran Bich; Duan YuanJiao; Nguye...
  第52回日本免疫学会学術集会/2024-01-17--2024-01-19
• The Roles of Immune Cells Derived from Clonal Hematopoiesis in Colorectal Cancer Metastasis
  Nguyen Tran Bich; Le Ai Nhan Thi; Duan YuanJiao; Abe ...
  65th ASH Annual Meeting and Exposition/2023-12-09--2023-12-12
• Distinct Minor Neoplastic Follicular T-Cell Subsets Dictate Lymphoma Fates through Functional Specialization
  Abe Yoshiaki; Zenkoh Junko; Ikeda Daisuke; Aya Sawa; ...
  65th ASH Annual Meeting and Exposition/2023-12-09--2023-12-12
• Outcome of TP53-mutated myelodysplastic syndrome: a single center experience
  Yutaro Tarui; Tatsuhiro Sakamoto; Naoki Kurita; Yumiko...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• The roles of immune cells derived from clonal hematopoiesis in colon cancer metastasis
  Nguyen Tran B.; Duan YuanJiao; Le Ai-Nhan T.; Nguyen ...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• Investigation of clonal hematopoiesis in new Japanese cohort
  Kenichi Makishima; Yukie Kashima; Yuta Kuze; Sakurako ...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• 造血幹細胞移植患者におけるタクロリムスとレテルモビルの薬物相互作用： タクロリムスの投与経路が薬物相互作用に及ぼす影響（第2報）
  森山 侑太; 末原 泰人; 坂本 竜弘; 加藤 貴康; 横山 泰久; 錦井 秀和; 千葉　滋; 鈴木 ...
  第49回日本臓器保存生物医学会学術集会/2023-10-20--2023-10-21
• Inter- and intra-tumor heterogeneity of T follicular helper cell lymphomas at single-cell resolution
  Sakurako Suma; Yasuhito Suehara; Manabu Fujisawa; Yosh...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• Pan-cancer single T-cell landscape delineates distinct neoplastic follicular T-cell subsets
  Yoshiaki Abe; Junko Zenkoh; Daisuke Ikeda; Aya Sawa; ...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• Safety of romiplostim administered immediately after CBT: A phase 1 trial (PROMPT-1)
  Naoki Kurita; Hidekazu Nishikii; Yumiko Maruyama; Yasu...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15
• The roles of immune cells derived from clonal hematopoiesis in colorectal liver metastasis
  Nguyen Tran B.; Duan Yuan J.; Le Ainhan T.; Nguyen Ye...
  第82回 日本癌学会学術総会/2023-09-21--2023-09-23
• Survival of CB and haploidentical transplantation were comparable to HLA-matched transplantation
  Yoshizawa Yuki; Kurita Naoki; Maruyama Yumiko; Nishiki...
  The 13th JSH International Symposium 2023 in Tsukuba/2023-07-21--2023-07-22
• Single-Cell analysis reveals immune-escape profiles in T-cell lymphoma microenvironment
  Suma Sakurako; Suehara Yasuhito; Fujisawa Manabu; Abe ...
  The 13th JSH International Symposium 2023 in Tsukuba/2023-07-21--2023-07-22
• The genetic subtypes and the tumor microenvironment signatures in peripheral T-cell lymphoma
  Suehara Yasuhito; Sakamoto Kana; Fujisawa Manabu; Abe ...
  The 13th JSH International Symposium 2023 in Tsukuba/2023-07-21--2023-07-22
• エトポシド投与を回避し，正常分娩に至った妊娠 9 週発症血球貪食性リンパ組織球症の 1 例
  樽井 祐太朗; 末原 泰人; 服部 圭一朗; 佐々木 裕哉; 丸山 ゆみ子; 坂本 竜弘; 加藤 貴...
  第19回 日本血液学会関東甲信越地方会/2023-07-15--2023-07-15
• ELOVL6 regulates engraftment of hematopoietic cells through the PI3K pathway
  Kiyoki Yusuke; Kato Takayasu; Kito Sakura; Matsuzaka ...
  2nd JCA-AACR Precision Cancer Medicine International Conference/2023-06-28--2023-06-30
• Single-Cell analysis reveals immune-escape profiles in T follicular helper cell lymphoma microenvironment
  Suma Sakurako; Suehara Yasuhito; Fujisawa Manabu; Abe ...
  2nd JCA-AACR Precision Cancer Medicine International Conference/2023-06-28--2023-06-30
• The genetic subtypes and the tumor microenvironment signatures are associated with distinct outcomes in peripheral T-cell lymphoma
  Suehara Yasuhito; Sakamoto Kana; Fujisawa Manabu; Fuku...
  2nd JCA-AACR Precision Cancer Medicine International Conference/2023-06-28--2023-06-30
• 脊柱管内に腫瘤を形成したリンパ形質細胞性リンパ腫に対するチラブルチニブと放射線照射の併用療法
  普天間 幸愛; 栗田 尚樹; 坂本 竜弘; 加藤 貴康; 服部 圭一朗; 末原 泰人; 横山泰久; 錦...
  第63回 日本リンパ網内系学会学術集会・総会/2023-06-22--2023-06-24
• The fatty acid elongase elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation
  Kiyoki Yusuke; Kato Takayasu; Kito Sakura; Matsuzaka ...
  The EHA 2023 Hybrid Congress/2023-06-08--2023-06-11
• Elongation of long-chain fatty acids is crucial for hematopoietic stem cell engraftment and leukemia propagation
  Kato Takayasu; Kiyoki Yusuke; Kito Sakura; Matsuzaka ...
  The 20th Stem Cell Research Symposium/2023-05-19--2023-05-20
• さらに表示...

担当授業科目

2024-01 -- 2024-02	ためになる血液学	筑波大学
2023-01 -- 2023-02	ためになる血液学	筑波大学
2022-01 -- 2022-02	ためになる血液学	医療科学類
2022-04 -- 2022-05	機能・構造と病態 II　#2 血液学	医学類

一般講演

• Association between microenvironment-related genes and prognosis of primary CNS lymphoma
  Keiichiro Hattori; Kenichi Makishima; Sakurako Suma; Y...
  第85回 日本血液学会学術集会/2023-10-13--2023-10-15

(最終更新日: 2024-04-10)