東端孝博(ヒガシバタタカヒロ)

所属

医学医療系

職名

講師

ORCID

0000-0002-1024-1946

性別

男性

生年月

1982-03

科研費番号

60869577

URL

https://palliative.md.tsukuba.ac.jp/

eメール

研究室

緩和支持治療科

学外所属


日本疫学会
日本プライマリ・ケア連合学会
日本緩和医療学会

取得学位


2013-03	博士（医学）	名古屋大学

免許資格等


2008-04	医師免許

所属学協会


2010-04 -- (現在)	日本疫学会
2013-06 -- (現在)	日本プライマリ・ケア連合学会
2013-04 -- (現在)	日本緩和医療学会

論文

Multicentre, double-blind, randomised, placebo-controlled study on the prophylactic use of naldemedine for opioid-induced nausea and vomiting in patients with cancer (POSEIDON study): a protocol paper
Ishihara Yo; Ohira Mayumi; Hokabe Mitsuki; Yoshino Sa...
BMJ open/16(7), 2026-07-17
PubMed
Outcomes in patients with cancer following opioid initiation in Japan: an exploratory study
Kessoku Takaomi; Higashibata Takahiro; Oyamada Shunsuk...
BMC RESEARCH NOTES/19(1), 2026-03-05
Cost-Effectiveness of Prophylactic Naldemedine for Opioid-Induced Constipation in Patients with Cancer
Okubo Reiko; Higashibata Takahiro; Kondo Masahide; Kes...
JOURNAL OF PALLIATIVE MEDICINE, 2026-04-10
Novel antiemetic effect of naldemedine in patients initiating opioids for cancer pain: a secondary analysis of a randomized clinical trial
Higashibata Takahiro; Kessoku Takaomi; Kajiura Shinya; ...
The oncologist/31(4), 2026-03-09
PubMed
Establishing the minimal important change for Patient Assessment of Constipation Quality of Life questionnaire for the prevention of opioid-induced constipation in patients with cancer pain
Higashibata Takahiro; Oyamada Shunsuke; Hamano Jun; Ke...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer/33(12), 2025-11-28
PubMed
Work-Life Balance, Social Support, and Professional Quality of Life Among End-of-Life Care Nurses: A Secondary Analysis
Higashibata Takahiro; Hamano Jun; Nagaoka Hiroka; Sasa...
NURSING & HEALTH SCIENCES/27(3), 2025-08-08
No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW
Hinohara Yukako; Naito Mariko; Okada Rieko; Yin Guan; ...
Nagoya journal of medical science/75(1-2)/pp.93-100, 2013-02-01
PubMed
Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial
Hamano Jun; Higashibata Takahiro; Kessoku Takaomi; Kaj...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology/42(35)/p.JCO2400381, 2024-09-10
PubMed
Naldemedine and Magnesium Oxide as First-Line Medications for Opioid-Induced Constipation: A Comparative Database Study in Japanese Patients With Cancer Pain
Kessoku Takaomi; Higashibata Takahiro; Morioka Yasuhid...
CUREUS JOURNAL OF MEDICAL SCIENCE/16(3), 2024-03-10
PubMed
Tapentadol Safety and Patient Characteristics Associated with Treatment Discontinuation in Cancer Therapy: A Retrospective Multicentre Study in Japan
Iwaki Michihiro; Kessoku Takaomi; Kanamori Taro; Abe ...
PAIN AND THERAPY/10(2)/pp.1635-1648, 2021-12
PubMed
Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population.
N Hamajima; M Naito; R Okada; S Kawai; G Yin; E Mor...
Gene/503/pp.131-136, 2012-07
PubMed
Trends in smoking rates among urban civil servants in Japan according to occupational categories
Higashibata Takahiro; Nakagawa Hiroko; Okada Rieko; Wa...
Nagoya journal of medical science/77(3)/pp.417-423, 2015-08-01
PubMed
DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study
Higashibata Takahiro; Naito Mariko; Mori Atsuyoshi; Oz...
Nagoya journal of medical science/75(1-2)/pp.73-80, 2013-02-01
PubMed
Associations of smoking status with other lifestyle behaviors are modified by sex and occupational category among urban civil servants in Japan
Higashibata Takahiro; Wakai Kenji; Okada Rieko; Nakaga...
Environmental health and preventive medicine/21(6)/pp.539-546, 2016-11-01
PubMed
Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change
Higashibata Takahiro; Wakai Kenji; Naito Mariko; Morit...
Gene/594(1)/pp.16-22, 2016-12-05
PubMed
eNOS genotype modifies the effect of leisure-time physical activity on serum triglyceride levels in a Japanese population
Higashibata Takahiro; Hamajima Nobuyuki; Naito Mariko; ...
Lipids in health and disease/11/p.150, 2012-11-05
PubMed
Family-Integrated Advance Care Planning for Cancer Patients: A Mixed-Methods Feasibility Study
Kishino Megumi; Koffman Jonathan; Hamano Jun; Higashib...
Journal of pain and symptom management/69(6), 2025-03-11
PubMed
A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer
Higashibata Takahiro; Kessoku Takaomi; Morioka Yasuhid...
PAIN AND THERAPY/12(4)/pp.993-1003, 2023-08
PubMed
Work Environmental Factors Associated with Compassion Satisfaction and End-of-Life Care Quality Among Nurses in General Wards, Palliative Care Units, and Home Care Settings: A Cross-Sectional Survey
Takahiro Higashibata; Jun Hamano; Hiroka Nagaoka; Tomo...
INTERNATIONAL JOURNAL OF NURSING STUDIES/143(E-pub), 2023-04-29
PubMed
Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol
Higashibata Takahiro; Hamano Jun; Kessoku Takaomi; Kaj...
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS/29, 2022-10-01
PubMed
Association of a home-based nursing service during chemotherapy with the transfer to home care immediately after the last chemotherapy treatment in patients with advanced cancer
Higashibata Takahiro; Iwata Naoko; Kazama Ikuko; Irie ...
JAPANESE JOURNAL OF CLINICAL ONCOLOGY/52(9)/pp.1039-1044, 2022-06-02
PubMed
Differences among institutions in the prevalence of and indications for urinary catheterization of advanced cancer patients at palliative care units: A multicenter prospective cohort study (EASED)
Higashibata Takahiro; Hisanaga Takayuki; Hagiwara Shin...
Palliative medicine/35(4)/pp.799-805, 2021-01
PubMed
Barriers to inpatient palliative care consultation among patients with newly diagnosed cancer after emergency admission
Higashibata Takahiro; Hisanaga Takayuki; Kobayashi Mik...
ANNALS OF PALLIATIVE MEDICINE/9(4)/pp.1571-1576, 2020-07
PubMed
Usefulness of painDETECT and S-LANSS in identifying the neuropathic component of mixed pain among patients with tumor-related cancer pain
Higashibata Takahiro; Tagami Keita; Miura Tomofumi; Ok...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer/28/pp.279-285, 2019-04
PubMed

会議発表等

Minimal important change (MIC) for opioid-induced constipation deterioration of the Patient Assessment of Constipation Quality of Life (PAC-QOL) in patients with cancer pain
Higashibata Takahiro; Kessoku Takaomi; Kajiura Shinya; ...
16th Asia Pacific Hospice Palliative Care Conference/2025-04-23--2025-04-26
個人の社会的なつながりと人生の最期を迎える場所の選好との関連：一般住民対象横断研究
東端孝博; 矢澤亜季; 孫瑜; 任明夏; 西浦千尋; 濵野　淳; 前野貴美; 前野哲博
第17回日本プライマリ・ケア連合学会学術大会/2026-05-30--2026-05-31
医学生の緩和ケア実習での体験についてのインタビュー調査：質的研究
濵野淳; 川島夏希; 木澤義之; 東端孝博; 矢吹律子; 久永貴之
第30回日本緩和医療学会学術大会/2025-07-04--2025-07-05
医学生の緩和ケア実習を選択したプロセスについてのインタビュー調査：質的研究
川島夏希; 木澤義之; 矢吹律子; 東端孝博; 濵野淳; 久永貴之
第30回日本緩和医療学会学術大会/2025-07-04--2025-07-05
オピオイドを開始するがん患者の便秘増悪におけるPatient Assessment of Constipation-Symptoms (PAC-SYM)のMinimal Important Change (MIC)
濵野淳; 東端孝博; 結束貴臣; 梶浦新也; 平川麻美; 小山田隼佑; 有吉恵介
第30回日本緩和医療学会学術大会/2025-07-04--2025-07-05
Secondary effects of prophylactic naldemedine administration on opioid-induced nausea and vomiting in patients with cancer pain
Higashibata Takahiro; Jun Hamano
The Multinational Association of Supportive Care in Cancer 2024/2024-06-27--2024-06-29

学協会等委員


2026-08 -- (現在)	日本緩和医療学会	学術大会支援メンバー作業部会/作業部会員
2026-08 -- (現在)	日本緩和医療学会	消化器ガイドライン改訂部会/副部会長
2026-08 -- (現在)	日本緩和医療学会	緩和ケア研修モジュール検討作業部会/作業部会員
2026-08 -- (現在)	日本緩和医療学会	緩和ケアの質評価部会/部会員
2026-08 -- (現在)	日本緩和医療学会	Palliative Care Research編集委員会/委員
2022-10 -- 2026-07	日本緩和医療学会	緩和ケア研修WPG/WPG員
2019-09 -- 2026-07	日本緩和医療学会	消化器症状ガイドライン改訂WPG/副委員長

学内管理運営業績


2025-04 -- (現在)	診療情報管理委員会	委員

(最終更新日: 2026-08-09)

東端 孝博(ヒガシバタ タカヒロ)

東端孝博(ヒガシバタタカヒロ)