土屋 輝一郎(ツチヤ キイチロウ)

研究者情報全体を表示

論文

• Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells
  Tatsuro Murano Ryuichi Okamoto Go Ito Toru Nakata Shu...
  Biochemical and Biophysical Research Communications/443(3)/pp.840-846, 2014-01
  
  PubMed
• Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine
  Hiromichi Shimizu Ryuichi Okamoto Go Ito Satoru Fujii ...
  PEERJ/2(1)/pp.e370-e370, 2014-05
  
  PubMed
• Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt
  Nobukatsu Horita Kiichiro Tsuchiya Ryohei Hayashi Keit...
  Biochemical and Biophysical Research Communications/454(4)/pp.493-499, 2014-11
  
  PubMed
• The Effect of TNF-α on the Regulation of Epithelial Function in Inflammatory Bowel Disease.
  Kiichiro Tsuchiya
  Frontiers of Gastrointestinal Research/34/pp.1-8, 2015-01
• TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy.
  Matsuzawa Yu; Oshima Shigeru; Takahara Masahiro; Maeyashi...
  Autophagy/11(7)/pp.1052-1062, 2015-01
  
  PubMed
• RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62
  Yu Matsuzawa Shigeru Oshima Yoichi Nibe Masanori Kobay...
  Biochemical and Biophysical Research Communications/456(1)/pp.298-304, 2015-01
  
  PubMed
• Associations of HLA class i alleles in Japanese patients with Crohn's disease
  Oryoji D.; Hisamatsu T.; Tsuchiya K.; Umeno J.; Ueda S.; ...
  Genes and Immunity/16(1)/pp.54-56, 2015-01
  
  PubMed
• Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer.
  Oshima Hiroko; Nakayama Mizuho; Han Tae-Su; Naoi Kuni...
  Cancer research/75(4)/pp.766-776, 2015-02
  
  PubMed
• Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line.
  Keita Fukushima Kiichiro Tsuchiya Yoshihito Kano Nobuk...
  CANCER SCIENCE/106(8)/pp.1000-1007, 2015-08
  
  PubMed
• Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease.
  Ryohei Hayashi Kiichiro Tsuchiya Keita Fukushima Nobuk...
  Inflammatory Bowel Diseases/22(5)/pp.1119-1128, 2016-05
  
  PubMed
• Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R
  Toshiyuki Kojima Kiichiro Tsuchiya Shinji Ikemizu Soic...
  SCIENTIFIC REPORTS/6/pp.36457-36457, 2016-11
  
  PubMed
• The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development
  Masanori Kobayashi Shigeru Oshima Chiaki Maeyashiki Yo...
  SCIENTIFIC REPORTS/6/pp.36780-36780, 2016-11
  
  PubMed
• PGE(2) is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells
  Satoru Fujii Kohei Suzuki Ami Kawamoto Fumiaki Ishibas...
  SCIENTIFIC REPORTS/6/pp.36795-36795, 2016-11
  
  PubMed
• Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors
  Toru Nakata Hiromichi Shimizu Sayaka Nagata Go Ito Sa...
  Biochemical and Biophysical Research Communications/482(4)/pp.1296-1303, 2017-01
  
  PubMed
• Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine
  Toru Nakata Hiromichi Shimizu Sayaka Nagata Go Ito Sa...
  Data in Brief/10/pp.551-556, 2017-02
  
  PubMed
• Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186
  Kosuke Fujimoto Makoto Kinoshita Hiroo Tanaka Daisuke ...
  MUCOSAL IMMUNOLOGY/10(2)/pp.446-459, 2017-03
  
  PubMed
• HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells
  Chiaki Maeyashiki Shigeru Oshima Kana Otsubo Masanori ...
  Biochemical and Biophysical Research Communications/484(3)/pp.636-641, 2017-03
  
  PubMed
• Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids
  Shuji Hibiya Kiichiro Tsuchiya Ryohei Hayashi Keita Fu...
  JOURNAL OF CROHNS & COLITIS/11(5)/pp.621-630, 2017-05
  
  PubMed
• Caudal type homeobox 2 expression induced by leukocytapheresis might be associated with mucosal healing in ulcerative colitis
  Kiichiro Tsuchiya Ryohei Hayashi Keita Fukushima Shuji...
  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY/32(5)/pp.1032-1039, 2017-05
  
  PubMed
• Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
  Fumiaki Ishibashi Hiromichi Shimizu Toru Nakata Satoru...
  Stem Cell Reports/10(1)/pp.27-42, 2018-01
  
  PubMed
• Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties
  Suzuki Kohei; Murano Tatsuro; Shimizu Hiromichi; Ito ...
  Journal of Gastroenterology/pp.1-13, 2018-01
  
  PubMed
• Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by SQSTM1/p62
  Yoichi Nibe Shigeru Oshima Masanori Kobayashi Chiaki M...
  Autophagy/14(2)/pp.347-358, 2018-02
  
  PubMed
• Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids.
  Ryu Nishimura Tomoaki Shirasaki Kiichiro Tsuchiya Yosh...
  J Gastroenterol/54(7)/pp.608-620, 2019-01
  
  PubMed
• Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients.
  Kawamoto Ami; Nagata Sayaka; Anzai Sho; Takahashi Jun...
  J Crohns Colitis/13(4)/pp.495-509, 2019-03
  
  PubMed
• A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors.
  Hiroshi Fukamachi Seon-Kyu Kim Jiwon Koh Hye Seung Lee...
  Journal of experimental & clinical cancer research : CR/38(1)/pp.127-127, 2019-03
  
  PubMed
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