CHIBA Tomoki
- Affiliation
- Institute of Life and Environmental Sciences
- Official title
- Professor
- Research fields
Molecular biology Cell biology - Research keywords
Ubiquitin posttranslational modification protein degradation stress response - Research projects
The Biology of the Ubiquitin system -- (current) /Grant-in-Aid for Scientific Research プロテアソーム活性化因子の機能的相互作用の解析 2011 -- 2013 Japan Society of for the Promotion of Science/基盤研究(C) 4,420,000Yen ユビキチンシステムの個体生物学 2006 -- 2010 Ministry of Education, Culture, Sports, Science and Technology, Japan/特定領域研究 55,300,000Yen - Career history
2005-11 -- (current) University of Tsukuba大学院生命環境科学研究科Professor 1998-07 -- 2005-11 東京都医学研究機構東京都臨床医学総合研究所主事 - Degree
1994-01 博士(医学) University of Tsukuba - Academic societies
-- (current) THE JAPANESE BIOCHEMICAL SOCIETY -- (current) The Molecular Biology Society of Japan -- (current) Japan Society for Cell Biology - Articles
- Cold shock protein RBM3 is upregulated in the autophagy-deficient brain
Nakamura Junnosuke; Aihara Takuma; Chiba Tomoki; Tsuru...
MicroPubl Biol., 2022-12 - Propagation of neuronal micronuclei regulates microglial states
Yano Sarasa; Asami Natsu; Kishi Yusuke; Kubotani Hika...
bioRxiv, 2023-8 - Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis
Ban Sato; Jiwoo Kim; Kazunori Morohoshi; Woojin Kang; ...
BIOMOLECULES/13(4)/p.586, 2023-03-24 - ECPAS/Ecm29-Mediated 26S Proteasome Disassembly Is an Adaptive Response to Glucose Starvation
Choi Won Hoon; Yun Yejin; Byun Insuk; Kim Sumin; Lee ...
CELL REPORTS/42(7), 2023-07 - A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain
Yano Sarasa; Akiyama Kaito; Tsuchiya Rio; Kubotani Hikar...
SCIENTIFIC REPORTS/11(1), 2021-09 - Proteasome activator PA200 maintains stability of histone marks during transcription and aging
Jiang Tian-Xia; Ma Shuang; Han Xia; Luo Zi-Yu; Zhu Q...
THERANOSTICS/11(3)/pp.1458-1472, 2021 - Quantification of Endosome and Lysosome Motilities in Cultured Neurons Using Fluorescent Probes
Tsuruta Fuminori; Okajima Tomomi; Yano Sarasa; Chiba Tomoki
Journal of visualized experiments : JoVE, 2017-05 - Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis
Qian MX; Pang Y; Liu CH; Haratake K; Du BY; Ji DY; Wang GF; Zhu ...
Cell/153(5)/pp.1012-1024, 2013-5 - A method for inducing antigen-specific IgG production by in vitro immunization
Kato Mieko; Yan Huimin; Tsuji Noriko M.; Chiba Tomoki; Ha...
JOURNAL OF IMMUNOLOGICAL METHODS/386(1-2)/pp.60-69, 2012-12 - Smad7-deficient mice show growth retardation with reduced viability
Tojo Masayoshi; Takebe Ai; Takahashi Satoru; Tanaka Keij...
JOURNAL OF BIOCHEMISTRY/151(6)/pp.621-631, 2012-06 - Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky Daniel J.; Abdalla Fabio C.; Abeliovich Hagai; A...
AUTOPHAGY/8(4)/pp.445-544, 2012-04 - Spermatogenesis arrest caused by conditional deletion of Hsp90α in adult mice
Kajiwara C; Kondo S; Uda S; Dai L; Ichiyanagi T; Chiba T...
Biology Open/1/p.977-982, 2012 - Inhibition of Gaussia luciferase Activity by a Monoclonal Antibody
Chiba Tomoki
Current Enzyme Inhibition/7(4)/pp.229-235, 2011-12 - Cell activation by CpG ODN leads to improved electrofusion in hybridoma production
Kato Mieko; Sasamori Eriko; Chiba Tomoki; Hanyu Yoshiro
JOURNAL OF IMMUNOLOGICAL METHODS/373(1-2)/pp.102-110, 2011-10 - Ubiquitin Ligase Activity of Cul3-KLHL7 Protein Is Attenuated by Autosomal Dominant Retinitis Pigmentosa Causative Mutation
Kigoshi Yu; Tsuruta Fuminori; Chiba Tomoki
JOURNAL OF BIOLOGICAL CHEMISTRY/286(38)/pp.33613-33621, 2011-09 - PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo
de Graaf Natascha; van Helden Mary J. G.; Textoris-Taube ...
EUROPEAN JOURNAL OF IMMUNOLOGY/41(4)/pp.926-935, 2011-04 - Bioluminescence Assay for Detecting Cell Surface Membrane Protein Expression
Kato Mieko; Chiba Tomoki; Li Min; Hanyu Yoshiro
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES/9(1)/pp.31-39, 2011-02 - Bioluminescence assay for detecting cell surface membrane protein expression.
Kato M; Chiba T; Li M; Hanyu Y.
Assay Drug Dev Technol./9/pp.31-39, 2010-01 - 2Ep14 The analysis of gene expression in vitro immune-system
加藤 三恵子; 笹森 えりこ; 千葉 智樹; 羽生 義郎
日本生物工学会大会講演要旨集/21(0)/p.64, 2009-08 - The mechanism of poly-NEDD8 chain formation in vitro
Ohki Yu; Konishi Natsumi; Funatsu Norikazu; Chiba Tomoki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS/381(3)/pp.443-447, 2009-04 - PML Activates Transcription by Protecting HIPK2 and p300 from SCFFbx3-Mediated Degradation
Shima Yutaka; Shima Takito; Chiba Tomoki; Irimura Tatsur...
MOLECULAR AND CELLULAR BIOLOGY/28(23)/pp.7126-7138, 2008-12 - Hsp90-mediated assembly of the 26 S proteasome is involved in major histocompatibility complex class I antigen processing
Yamano Taketoshi; Mizukami Shusaku; Murata Shigeo; Chiba ...
JOURNAL OF BIOLOGICAL CHEMISTRY/283(42)/pp.28060-28065, 2008-10 - A new ubiquitin ligase involved in p57(KIP2) proteolysis regulates osteoblast cell differentiation
Kim Minsoo; Nakamoto Takashi; Nishimori Shigeki; Tanaka ...
EMBO REPORTS/9(9)/pp.878-884, 2008-09 - Allele-selective effect of PA28 in MHC class I antigen processing
Yamano Taketoshi; Sugahara Hidetoshi; Mizukami Shusaku; M...
JOURNAL OF IMMUNOLOGY/181(3)/pp.1655-1664, 2008-08 - Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.
Koyama S; Hata S; Witt CC; Ono Y; Lerche S; Ojima K; Chib...
J Mol Biol./376/pp.1224-1236, 2008-01 - more...
- Cold shock protein RBM3 is upregulated in the autophagy-deficient brain
- Books
- 生物学事典
千葉 智樹
東京化学同人, 2010-12 - CELL BIOLOGY
沼田治; 中野賢太郎; 中田和人; 千葉 智樹
化学同人, 2012 - ヒトの生物学
千葉 智樹
2007-01 - 分子細胞生物学事典
千葉 智樹
2009-01
- 生物学事典
- Conference, etc.
- ⼤脳⽪質構造の維持におけるUSP15の機能の解明
植松雪乃; Kiwon Park; 濱⽥ 千晴; 千葉 智樹; 鶴田 文憲
第46回日本分子生物学会/2023-12-06--2023-12-08 - Elucidating the role of USP15 in the cortical layer formation
植松 雪乃; Park Kiwon; 濱田 千晴; 千葉 智樹; 鶴田文憲
第16回神経発生討論会/2023-03-10--2023-03-11 - 大脳皮質層形成におけるUSP15の役割の解明
植松 雪乃; Park Kiwon; 濱田 千晴; 千葉 智樹; 鶴田 文憲
第45回日本分子生物学会/2022-11-30--2022-12-02 - ASD-like phenotypes and brain abnormalities in USP15 KO mouse
Park Kiwon; Uematsu Yukino; Hamada Chiharu; Chiba Tomoki...
TGSW2022/2022-09-26--2022-09-30 - Elucidating the role of USP15 in the cortical layer formation
Uematsu Yukino; Park Kiwon; Hamada Chiharu; Chiba Tomoki...
TGSW2022/2022-09-26--2022-09-30 - A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain
Yano Sarasa; Akiyama Kaito; Tsuchiya Rio; Kubotani Hikar...
SCIENTIFIC REPORTS/2021-09 - 発達過程において神経細胞のオートファジーはグリア細胞の活性制御に重要である
秋山 海大; 矢野 更紗; 窪谷 ひかり; 佐藤伴; 千葉智樹; 鶴田 文憲
第43回 日本分子生物学会/2020-12-02--2020-12-04 - EFハンド機能欠損SPARCL1変異体は小胞体ストレスを誘導する: 自閉症発症メカニズムの新たな可能性
武富 巧; 濱田 千晴; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本分子生物学会/2020-12-02--2020-12-04 - アストロサイトによる双極性障害関連遺伝子RBM3の発現制御機構の解明
土屋 里緒; 中村 準之助; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本分子生物学会/2020-12-02--2020-12-04 - 発達過程における微小核を介した神経細胞―ミクログリア間の情報伝播
矢野 更紗; 窪谷 ひかり; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第1回 脳科学サロン/2020-08-15 - Usp15欠損により産生されるSparcl1変異体は小胞体ストレスを引き起こす:自閉症責任遺伝子との関連性
武富 巧; 濱田 千晴; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - 脳構築時期におけるUSP15は興奮性シナプスと抑制性シナプスのバランスを制御する
濱田 千晴; 中村 準之助; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - 神経活動依存的なミクログリア形質変化を制御する新規因子の探索
顧 伊晨; 岡島 智美; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - 発達過程におけるミクログリアcGAS-STING経路の活性制御
窪谷 ひかり; 矢野 更紗; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - オートファジーはRBM3を介して低温下における体温を制御する
中村 準之助; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - 発達過程における微小核を介した神経細胞―ミクログリア間の情報伝播
矢野 更紗; 窪谷 ひかり; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - 非定型カドヘリンFat3は若齢期のミクログリア形態変化に重要である
岡島 智美; 顧 伊晨; 佐藤 伴; 千葉 智樹; 鶴田 文憲
第43回 日本神経科学大会/2020-07-29--2020-08-01 - Analysis of male infertility in proteasome-associated protein PA200/Ecm29 double knockout mouse.
佐藤 伴; 千葉智樹
Consortium of Biological Sciences 2017/2017-12-07 - The Regulation of Nrf2-Keap1 Antioxidant Response by a Novel Cullin-like Protein
Chiba Tomoki
Cold Spring Harbor Laboratory Meeting (The Ubiquitin Family)/2013-05-14 - A novel NEDD8-binding protein modulates NF-kappa B signaling pathway
Takashima Osamu; Tsuruta Fuminori; Ebina Manato; Kigoshi ...
8th Meeting of the Global Arthritis Research Network (GARN)/1st Bio-Rheumatology International Congress (BRIC)/2011-11-14--2011-11-16
- ⼤脳⽪質構造の維持におけるUSP15の機能の解明
- Teaching
2024-04 -- 2024-08 Special Research in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Humanics IIIb University of Tsukuba. 2024-10 -- 2025-02 Basic Experiments in Human Biology University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Human Biology I University of Tsukuba. 2024-10 -- 2025-02 Special Lectures in Humanics IIIb University of Tsukuba. 2024-04 -- 2024-09 Cooperative Education through Research Internships( Life and Earth Sciences) University of Tsukuba. 2024-10 -- 2025-03 Cooperative Education through Research Internships( Life and Earth Sciences) University of Tsukuba. 2024-04 -- 2024-08 Special Lectures in Humanics IIIa University of Tsukuba. 2024-04 -- 2024-08 Special Seminars in Humanics IIIa University of Tsukuba. 2024-10 -- 2025-02 Special Seminars in Human Biology II University of Tsukuba. more... - Professional activities
-- (current) THE JAPANESE BIOCHEMICAL SOCIETY 評議員
(Last updated: 2024-08-26)