TAKAYA Naoki

Affiliation

Institute of Life and Environmental Sciences

Official title

Professor

Research projects


超地球生命体を解き明かすポストコッホ生態学	2024-04 -- 2025-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area)	3,900,000Yen
Modeling the post-Koch ecosystem	2019-07 -- 2024-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas	176,800,000Yen
Post-Koch Ecology - The next-era microbial ecology	2019-07 -- 2024-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)	106,860,000Yen
Development of natural inducers for producing fungal dormant secondary metabolites	2019-04 -- 2022-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B)	17,550,000Yen
バイオマスプラスチック原料生産における課題抽出、対策検討	2017-10 -- (current)	TAKAYA Naoki	Japan Advanced Institute of Science and Technology/	19,872,000Yen
Heterogenous organization of multicellular fungal hyphal cells	2016-04 -- 2019-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for challenging Exploratory Research	3,640,000Yen
Fungal mechanisms for tolerance and adaptation to environmental stresses	2015-04 -- 2019-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(A)	24,310,000Yen
Research of microbial metabolisms that function in soil-humic acid homeostasis	2014-07 -- 2017-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (B)	16,380,000Yen
汎用的な生合成マシナリー発現誘導物質の検索と物質生産	2013-04 -- 2015-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)	6,760,000Yen
Diversity and molecular evolution of eukaryotic electron transfer mechanisms	2012-04 -- 2015-03	TAKAYA Naoki	Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (B)	15,990,000Yen
more...

Academic background


-- 1991	The University of Tokyo Faculty of Agriculture 農芸化学科
-- 1996	The University of Tokyo Graduate School, Division of Agriculture 応用生命工学

Degree


1968-03	Ph. D. (Agriculture)	The University of Tokyo

Academic societies


-- (current)	JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

Honors & Awards


2012-02-27	第8回日本学術振興会賞

Articles

Fungal glyceraldehyde 3-phosphate dehydrogenase GpdC maintains glycolytic mechanism against reactive nitrogen stress-induced damage
Kadooka Chihiro; Katsuki Nozomi; Masuo Shunsuke; Kojim...
FRONTIERS IN MICROBIOLOGY/15, 2024-10-11
Photocatalytic scaffolds enhance anticancer performances of bacterial consortium AUN
Miyahara Mikako; Doi Yuki; Takaya Naoki; Miyako Eijiro
CHEMICAL ENGINEERING JOURNAL/499, 2024-11-01
Temporal and fertilizer-dependent dynamics of soil bacterial communities in buckwheat fields under long-term management
Morigasaki Susumu; Matsui Motomu; Ohtsu Iwao; Doi Yuk...
SCIENTIFIC REPORTS/14(1), 2024-04-30
Roseiterribacter gracilis gen. nov., sp. nov., a novel filterable alphaproteobacterium isolated from soil using a gel-filled microwell array device
Nakai Ryosuke; Kusada Hiroyuki; Sassa Fumihiro; Makino...
PLOS ONE/19(6), 2024-06-10
Metabolic engineering for 4-aminophenylalanine production from lignocellulosic biomass by recombinant Escherichia coli.
Kawaguchi Hideo; Masuo Shunsuke; Wakai Keiko; Takaya ...
RSC Sustain., 2023-05
Gallic acid fermentation by metabolically engineered Escherichia coli producing p-hydroxybenzoate hydroxylase from Hylemonella gracilis NS1
Katsuki Nozomi; Masuo Shunsuke; Nukui Noriyuki; Minaka...
JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY/69(6)/pp.301-308, 2023-08-30
PubMed
Protocatechuate hydroxylase is a novel group A flavoprotein monooxygenase with a unique substrate recognition mechanism
Katsuki Nozomi; Fukushima Riku; Doi Yuki; Masuo Shuns...
The Journal of biological chemistry/300(1), 2024-01-01
PubMed
The Metabolic Regulation of Amino Acid Synthesis Counteracts Reactive Nitrogen Stress via Aspergillus nidulans Cross-Pathway Control
Amahisa Madoka; Tsukagoshi Madoka; Kadooka Chihiro; Ma...
JOURNAL OF FUNGI/10(1), 2024-01-10
PubMed
Metallothionein Cup1 attenuates nitrosative stress in the yeast Saccharomyces cerevisiae
Yoshikawa Yuki; Nasuno Ryo; Takaya Naoki; Takagi Hiroshi
MICROBIAL CELL/10(8)/pp.170-177, 2023-08
Cytosol Peroxiredoxin and Cell Surface Catalase Differentially Respond to H₂O₂ Stress in Aspergillus nidulans
Yan Yunfeng; Huang Xiaofei; Zhou Yao; Li Jingyi; Liu ...
ANTIOXIDANTS/12(7), 2023-07
Microbial pyrazine diamine is a novel electrolyte additive that shields high-voltage LiNi_1/3Co_1/3Mn_1/3O₂ cathodes
Gupta Agman; Badam Rajashekar; Takamori Noriyuki; Mina...
Scientific reports/12(1), 2022-11-25
PubMed
Carboxypeptidase G and pterin deaminase metabolic pathways degrade folic acid in Variovorax sp. F1
You Yungmi; Doi Yuki; Maeda Norifumi; Masuo Shunsuke; ...
BMC microbiology/22(1)/p.225, 2022-09-27
PubMed
Machine learning-assisted medium optimization revealed the discriminated strategies for improved production of the foreign and native metabolites
Aida Honoka; Uchida Keisuke; Nagai Motoki; Hashizume Tak...
Computational and structural biotechnology journal/21/pp.2654-2663, 2023-04-23
PubMed
Local calcium signal transmission in mycelial network exhibits decentralized stress responses
Itani Ayaka; Masuo Shunsuke; Yamamoto Riho; Serizawa ...
PNAS NEXUS/2(3)/p.pgad012, 2023-03-01
PubMed
Machine learning-assisted medium optimization revealed the discriminated strategies for improved production of the foreign and native metabolites.
AIDA Honoka; UCHIDA Keisuke; NAGAI Motoki; HASHIZUME ...
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL/21/pp.2654-2663, 2023-02
Carboxypeptidase G and pterin deaminase metabolic pathways degrade folic acid in Variovorax sp. F1
You Yungmi; Doi Yuki; Maeda Norifumi; Masuo Shunsuke; Tak...
BMC MICROBIOLOGY/22(1)/p.225, 2022-09-27
PubMed
Glucose-Derived Raspberry Ketone Produced via Engineered Escherichia coli Metabolism
Masuo Shunsuke; Saga Chisa; Usui Kurumi; Sasakura Yum...
Frontiers in bioengineering and biotechnology/10, 2022-02-14
PubMed
Fermentative production of 2-(4-aminophenyl)ethylamine to synthesize a novel heat-resistant biopolyurea
Minakawa Hajime; Masuo Shunsuke; Takada Kenji; Kumakur...
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY/86(8)/pp.1114-1121, 2022-07-22
PubMed
Draft genome sequence of novel filterable Rhodospirillales bacterium strain TMPK1, isolated from soil
Nakai Ryosuke; Kusada Hiroyuki; Sassa Fumihiro; Morigasak...
Microbiology Resource Announcements/10(28)/p.e00393-21, 2021-07
Trade-off between Plasticity and Velocity in Mycelial Growth
Fukuda Sayumi; Yamamoto Riho; Yanagisawa Naoki; Takaya...
mBio/12(2), 2021-04-16
PubMed
Ultrahigh Thermoresistant Lightweight Bioplastics Developed from Fermentation Products of Cellulosic Feedstock
Nag Aniruddha; Ali Mohammad Asif; Kawaguchi Hideo; Sai...
ADVANCED SUSTAINABLE SYSTEMS/5(1), 2020-10
Fungal mycelia and bacterial thiamine establish a mutualistic growth mechanism
Gayan Abeysinghe; Kuchira Momoka; Masuo Shunsuke; Takahas...
LIFE SCIENCE ALLIANCE/3(12), 2020-09
PubMed
Invasive growth of Aspergillus oryzae in rice koji and increase of nuclear number
Yasui Mizuki; Oda Ken; Masuo Shunsuke; Hosoda Shuji; Kata...
Fungal Biology and Biotechnology, 2020-06
Invasive growth of Aspergillus oryzae in rice koji and increase of nuclear number
Yasui Mizuki; Oda Ken; Masuo Shunsuke; Hosoda Shuji; Kata...
Fungal Biology and Biotechnology/7/p.8, 2020-06
PubMed
Symbiotic riboflavin degradation by Microbacterium and Nocardioides bacteria
Kanazawa Hiroshi; Ozaki Sayoko; Doi Yuki; Masuo Shunsuke...
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY/84(5)/pp.1056-1061, 2020-05
PubMed
more...

Books

第6章　微生物の遺伝と遺伝子工学
中西　載慶; 青柳　秀紀; 石川　森夫; 泉　秀美; 北村　義明; 篠山　浩文; 高橋　将人; 高谷　直樹; 中島...
エッセンシャル　応用微生物学/講談社/pp.114-149, 2025-05
大腸菌への人工生合成経路の導入によるラズベリーケトン生産
桝尾俊介; 薄井くるみ; 高谷直樹
B&I バイオサイエンスとインダストリー/（一財）バイオインダストリー協会, 2023-09-10

Conference, etc.

Novel electron transfer protein to cytochrome P450 monooxygenase to catalyze fatty acid β-hydroxylation
小島才卓; 鈴木康太; 勝木希; 進士恭誠; 桝尾俊介; 志水元亨; 高谷直樹
第23 回糸状菌分子生物学コンファレンス/2024-11-03--2024-11-04
Medium-chain fatty acid degradation tolerates nitric oxide stress in Aspergillus nidulans.
進士恭誠; 小島才卓; 桝尾俊介; 高谷直樹
第23 回糸状菌分子生物学コンファレンス/2024-11-03--2024-11-04
Analysis of defense response and recognition mechanism of filamentous fungi against bacteria
笠井拓実; 戸田征宏; ABEYSINGHE Gayan; 菅澤威仁; 桝尾俊介; 高谷直樹; 竹下典男
日本農芸化学会2025年度大会/2025-03-04--2025-03-08
Exploration of transcriptional regulators involved in ergothionein biosynthesis in Aspergillus oryzae.
佐々木優; 薄井くるみ; 桝尾俊介; 高谷直樹
日本農芸化学会2025年度大会/2025-03-04--2025-03-08
Development of a microbial production system for diphenylpyrazine
森下希; 桝尾俊介; 高谷直樹
日本農芸化学会2025年度大会/2025-03-04--2025-03-08
Exploration of Novel Oxo-Amine Synthases Enabling the Bioproduction of Symmetric Pyrazines
戸塚璃々; 桝尾俊介; 高谷直樹
日本農芸化学会2025年度大会/2025-03-04--2025-03-08
High production of Raspberry ketone through ribosome binding site optimization in recombinant E.coli.
薄井くるみ; 桝尾俊介; 高谷直樹
日本農芸化学会2025年度大会/2025-03-04--2025-03-08
ジフェニルピラジンの微生物生産系の開発と律速段階の特定
森下希; 桝尾俊介; 高谷直樹
日本農芸化学会関東支部2024年度大会/2024-08-30
Aspergillus nidulansにおける2つの遺伝子クラスターを介したNOストレス耐性機構の機能解明
天久まどか; 桝尾俊介; 高谷直樹
日本農芸化学会2024年度大会/2024-03-24--2024-03-27
組換え大腸菌を用いたラズベリーケトンの高生産
薄井くるみ; 桝尾俊介; 高谷直樹
日本農芸化学会2024年度大会/2024-03-24--2024-03-27
一酸化窒素特異的な転写誘導を担う Aspergillus nidulans の転写因子の発見
天久まどか; 桝尾俊介; 高谷直樹
第 22 回糸状菌分子生物学コンファレンス/2023-11-21--2023-11-22
Aspergillus nidulans 由来新規 P450 還元酵素の機能解析
小島才卓; 鈴木康太; 勝木希; 桝尾俊介; 志水元亨; 高谷直樹
第 22 回糸状菌分子生物学コンファレンス/2023-11-21--2023-11-22
プロトカテク酸水酸化酵素の発見とその新規な触媒機構
勝木希; 福島陸; 桝尾俊介; 荒川孝俊; 山田千早; 伏信進矢; 高谷直樹
日本農芸化学会関東支部2023年度大会/2023-08-25
Metabolic optimization of an artificial biosynthetic pathway in Escherichia coli for high production of Raspberry Ketone.
USUI Kurumi; MASUO Shunsuke; Takaya Naoki
Asian Synthetic Biology Association Meeting 2023/2023-12-12--2023-12-16
Caffeic acid production from cellulose biomass using recombinant E. coli.
IJIRI Ayu; MASUO Shunsuke; Takaya Naoki
Asian Synthetic Biology Association Meeting 2023/2023-12-12--2023-12-16
Metabolic optimization of an artificial biosynthetic pathway in Escherichia coli for high production of Raspberry Ketone.
USUI Kurumi; MASUO Shunsuke; Takaya Naoki
Metabolic Engineering 15/2023-06-11--2023-06-15
Rhodococcus sp. LC-2株のルミクロム分解機構の解明
塩田大地; 土肥裕希; 高谷直樹
日本微生物生態学会　第36回大会/2023-11-27--2023-11-30
Rhodococcus sp. LC-2株のルミクロム分解機構の解明
塩田大地; 土肥裕希; 高谷直樹
日本農芸化学会　2024年度大会/2024-03-23--2024-03-28
Rhodococcus sp. LC-2株のルミクロム分解を担う新規Cytochrome P450水酸化酵素の解析
土肥裕希; 塩田大地; 高谷直樹
日本農芸化学会　関東支部　2023年度大会/2023-08-25--2023-08-25
Rhodococcus sp. LC-2 株のルミクロム分解機構の解明
塩田大地; 土肥裕希; 高谷直樹
環境バイオテクノロジー学会　2023年度大会/2023-06-08--2023-06-09
Filamentous fungi release extracellular vesicles at log- and stationary phases
Urayama Shunichi; Saito Mio; Iwahashi Yuka; Itani Aya...
32nd Fungal Genetics Conference/2024-03-12--2024-03-17
環境土壌における葉酸資化性菌の群衆構造解析
戸田征宏; 前田典歩; 土肥裕希; 高谷直樹
日本農芸化学会　2023年度大会/2023-03-14--2023-03-17
Cupriavidus sp. LA-1株のプテリジン化合物分解機構の解明
土肥裕希; 前田典歩; 高谷直樹
日本農芸化学会　2023年度大会/2023-03-14--2023-03-17
微生物生態系における細菌のリボフラビンおよびルミクロム分解
土肥裕希; 鈴木麻奈美; 前田典歩; 尾崎紗代子; 高谷直樹
環境バイオテクノロジー学会　2021年度大会/2021-09-02--2021-09-03
新規なフラビン酵素が触媒するプロトカテク酸の水酸化とその反応機構
勝木希; 福島陸; 桝尾俊介; 荒川孝俊; 山田千早; 伏信進矢; 高谷直樹
日本農芸化学会2023年度大会/2023-03-14--2023-03-17
more...

Intellectural property rights

微生物菌株、タンパク質、微生物菌株又はタンパク質を用いた没食子酸を製造する方法
高谷直樹; 貫井憲之; 勝木希; MASUO Shunsuke
二次電池正極安定化剤、その生産方法、その化合物を用いる正極材安定化方法、及びその化合物を含む電解液
松見紀佳; バダムラーシャシェーカル; グプタアグマン; 高谷直樹; 桝尾俊介; 皆川一
二次電池正極安定化剤、その生産方法、その化合物を用いる正極材安定化方法、及びその化合物を含む電解液
松見紀佳; バダムラーシャシェーカル; グプタアグマン; 高谷直樹; 桝尾俊介; 皆川一
Method for producing aniline derivative by fermentation from carbon source
小西一誠; 高谷直樹; 桝尾俊介

Teaching


2024-04 -- 2024-08	Seminar in Applied Biochemistry IIF（Spring）	University of Tsukuba.
2024-04 -- 2024-08	Research in Applied Biochemistry IIF（Spring）	University of Tsukuba.
2024-04 -- 2024-08	Seminar in Life and Agricultural Sciences	University of Tsukuba.
2024-10 -- 2025-02	Seminar in Life and Agricultural Sciences	University of Tsukuba.
2024-10 -- 2024-12	Genes and Genomes as Biological Resources	University of Tsukuba.
2024-10 -- 2025-02	Research in Applied Biochemistry IF	University of Tsukuba.
2024-04 -- 2024-08	Research in Applied Biochemistry IIS	University of Tsukuba.
2024-10 -- 2024-12	Biotechnology, Laboratory	University of Tsukuba.
2024-04 -- 2024-08	Advanced Ecological Molecular Microbiology	University of Tsukuba.
2024-10 -- 2025-02	Advanced Ecological Molecular Microbiology	University of Tsukuba.
more...

Professional activities


2017-04 -- 2020-03	日本農芸化学会	倫理委員
2005 -- 2007	JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY	関東支部幹事

University Management


2018-10 -- 2022-03	研究推進会議	委員
2018-10 -- 2022-03	微生物サステイナビリティ研究センター	センター長
2017-04 -- 2020-03	生命環境科学研究科教務委員

(Last updated: 2025-05-08)