MIYOSHI Hirotoshi

Affiliation
Institute of Medicine
Official title
Assistant Professor
Sex
Male
KAKEN ID
70292547
URL
Email
5384D:>34N]Y8/W?>@6@-,W,.W5;d
Fax
029-853-3254
Research fields
General physiology
Research keywords
Tissue Engineering
Biomedical Engineering
Artificial Organ
Research projects
Three-dimensional cultures of leukemia cells to achieve effective therapies targeting leukemic stem cells2024-04 -- 2028-03MIYOSHI HirotoshiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)4,680,000Yen
Ex vivo reconstruction of hematopoietic function using 3D culture of umbilical cord blood cells2020-04 -- 2023-03MIYOSHI HirotoshiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)4,290,000Yen
Ex vivo reconstruction of hematopoietic functions using three-dimensional freeze-thawed feeder cell layer2016 -- 2018MIYOSHI HirotoshiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)4,680,000Yen
Establishment of ex vivo expansion method of hematopoietic progenitor cells using 3D fixed feeder cells2012-04 -- 2016-03Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)5,330,000Yen
Development of a bioreactor with high growth efficiency for an indifferent cellar as a stem cell by using the chaos mixing Taylor vortex flow2009 -- 2011KAWAI HidekiJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)
Development of ex vivo expansion system of hematopoietic stem/progenitor cells using stromal cells fixed on three-dimensional scaffolds2009 -- 2011Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)4,550,000Yen
Development of in vitro expansion method of hematopoietic progenitor/stem cells using surface molecules of stromal cells on three-dimensional scaffold2007 -- 2008Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)4,550,000Yen
Development of tissue-engineered artificial immune system2004 -- 2004Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (A)50,310,000Yen
Development of a tissue-engineered bioartificial liver utilizing immature cells2002 -- 2003Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)3,800,000Yen
Regeneration of immature tissue (fetal liver) functions utilizing a tissue-engineering approach2000 -- 2001Hirotoshi MIYOSHIJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research (C)3,800,000Yen
more...
Career history
1989-04 -- 1997-03Kaneka CorporationResearcher
1997-04 -- 2011-09University of TsukubaInstitute of Basic Medical SciencesAssistant Professor
2011-10 -- (current)University of TsukubaFaculty of MedicineAssistant Professor
Academic background
-- 1987Kyoto University Faculty of Engineering Chemical Engineering
-- 1989Kyoto University Graduate School, Division of Engineering Chemical Engineering
Degree
Master of EngineeringKyoto University
Ph.D.(Medical Sciences)University of Tsukuba
Academic societies
-- (current)THE SOCIETY OF CEMICAL ENGINEERS, JAPAN
-- (current)JAPANESE SOCIETY FOR MEDICAL AND BIOLOGICAL ENGINEERING
-- (current)THE JAPAN SOCIETY FOR ARTIFICIAL ORGANS
Honors & Awards
1999ASAIO Fellowshiop Award
Articles
Books
  • Efficient proliferation and maturation of fetal liver cells in three-dimensional culture by stimulation of oncostatin M, epidermal growth factor, and dimethyl sulfoxide
    Koyama T; Ehashi T; Ohshima N; Miyoshi H
    Advances in Tissue Engineering: Volume 2 - Stem Cells/Mary Ann Liebert, Inc./pp.312-320, 2010-01
  • Long-term three-dimensional culture of fetal liver cells to achieve prolonged metabolic functions
    Miyoshi H; Ehashi T; Ohshima N
    Tissue Engineering for Therapeutic Use 6/Elsevier Science BV/pp.75-81, 2002-01
  • Improvement of the performance of a packed-bed bioartificial liver
    Ohshima N; Yanagi K; Miyoshi H; Kan P
    Tissue Engineering for Therapeutic Use 3/Elsevier Science BV/pp.53-63, 1999-01
  • Hepatocyte culture utilizing porous polyvinyl formal resin maintains long-term stable albumin secretion activity
    Miyoshi H; Ookawa K; Ohshima N
    Polymers for Tissue Engineering/VSP/pp.287-297, 1998-02
  • A packed-bed bioreactor utilizing reticulated polyvinyl formal resin to attain high density culture of hepatocytes.
    Yanagi K; Miyoshi H; Ohshima N
    Biochemical Engineering for 2001/Springer-Verlag/pp.353-355, 1992-01
Conference, etc.
  • A novel design of biointerface suppressing immune response on the substrate surface
    Ikeda Yutaka; Yoshinari Tomoki; Akasaka Kouya; Miyoshi H...
    The 11th SPSJ International Polymer Conference/2016-12-13--2016-12-16
  • Construction of oxidative stress-free biointerface for the separation of hematopoietic stem cells
    池田 豊; 吉成 友貴; 三好 浩稔; 長崎 幸夫
    第25回日本MRS年次大会/2015-12-09
  • Impact of scavenging oxidative stress during cell treatments
    Ikeda Yutaka; Yoshinari Tomoki; Miyoshi Hirotoshi; Nagasaki ...
    7th Biennial Meeting of Society for Free Radical Research-Asia/2015-11-30
  • 細胞操作において生じる酸化ストレスを消去するバイオ界面の設計
    池田 豊; 吉成 友貴; 三好 浩稔; 長崎 幸夫
    第37回日本バイオマテリアル学会大会/2015-11-09--2015-11-10
  • 活性酸素を消去するバイオ界面の設計と細胞分離 基材への応用
    池田 豊; 吉成 友貴; 三好 浩稔; 長崎 幸夫
    高分子学会第64回高分子討論会/2015-09-15
  • Construction of the oxidative stress-free cell culture system
    Ikeda Yutaka; Yoshinari Tomoki; Miyoshi Hirotoshi; Nagasaki ...
    Hierarchical Dynamics in Soft Materials and Biological Matter/2015-09-23
  • 活性酸素を消去する細胞分離基材の設計と造血幹細胞培養への応用
    池田　豊; 吉成友貴; 三好浩稔; 長崎 幸夫
    第68回日本酸化ストレス学会学術集会/2015-06-12
Intellectural property rights
  • 血液中の有核細胞成分濃縮方法
    三好浩稔; 原顯寛; 高木健太郎; 益城賢太郎
  • 細胞培養支持体、その製造方法及び該支持体を用いた細胞培養方法
    三好浩稔; 小山寿恵; 清水雄一郎
  • 人工骨髄、血球細胞の増殖方法
    大島宣雄; 三好浩稔; テイントゥン
  • 動物細胞の保存方法
    大島宣雄; 三好浩稔
  • 動物細胞の固定化方法
    大島宣雄; 三好浩稔; 楊宗樺
  • 動物細胞の固定化物および培養方法
    大島宣雄; 柳健一; 三好浩稔; 山地秀樹
  • 動物遊離細胞の固定化物、固定化方法および培養方法
    大島宣雄; 柳健一; 三好浩稔; 福田秀樹
  • リン脂質の製造方法
    三好浩稔; 中嶋敏光; 福田秀樹
  • リン脂質の製造法
    三好浩稔; 中嶋敏光; 福田秀樹
  • リン脂質の分離方法
    三好浩稔; 中嶋敏光; 福田秀樹
Teaching
2025-04 -- 2025-06基礎医学総論医療科学類
2024-10 -- 2024-12Introduction of Medical ScienceUniversity of Tsukuba.
2024-04 -- 2024-08Lecture and Discussion in Human Medical Biology IUniversity of Tsukuba.
2024-10 -- 2025-02Lecture and Discussion in Human Medical Biology IIUniversity of Tsukuba.
2024-10 -- 2025-02Frontier of Clinical Laboratory ScienceUniversity of Tsukuba.
2024-07 -- 2024-08Engineering for Clinical MedicineUniversity of Tsukuba.
2024-05 -- 2024-06Artificial OrgansUniversity of Tsukuba.
2024-10 -- 2025-02Practice in Human Medical Biology IIUniversity of Tsukuba.
2024-04 -- 2024-07Introduction to Biomedical EngineeringUniversity of Tsukuba.
2024-05 -- 2024-08Technology for Medical ScienceUniversity of Tsukuba.
more...
Other educational activities
2019 -- 2022クラス担任医学群医療科学類
2011 -- 2014クラス担任医学群医療科学類
Talks
  • バイオ人工臓器の開発ー臨床応用に向けての倫理も含めて
    三好浩稔
    第３回産学民協働セミナー/2008-07-04--2008-07-04
  • 三次元培養細胞を用いたバイオ人工臓器
    三好浩稔
    神戸大学大学院自然科学研究科　バイオエンジニアリングセミナー/2007-01-12--2007-01-12
  • 三次元培養細胞を用いたバイオ人工臓器の開発
    三好浩稔
    第１２５年会　日本薬学会/2005-03-31--2005-03-31
Professional activities
2000 -- (current)THE JAPAN SOCIETY FOR ARTIFICIAL ORGANS評議員
University Management
2022 -- 2023大学院共通科目部会委員
2022 -- 2023筑波大学教学情報システム運用委員会委員
2022 -- 2022医学群医療科学類学生生活委員会委員
2021 -- 2023医学群医療科学類キャリア支援委員会委員長
2021 -- 2023医学群医療科学類カリキュラム委員会委員
2020 -- 2023大学院医学学位プログラム 運営委員会委員
2020 -- 2023大学院医学学位プログラム 教務委員会委員
2020 -- 2023大学院フロンティア医科学学位プログラム 運営委員会委員
2020 -- 2023大学院フロンティア医科学学位プログラム 教務委員会委員
2020 -- 2023大学院フロンティア医科学学位プログラム インターンシップ委員会委員長
more...
Other activities
2008-12 -- 2010-11独立行政法人 日本学術振興会　科学研究費委員会専門委員

(Last updated: 2025-05-21)