OKADA Takuya
- Affiliation
- Institute of Medicine
- Official title
- Assistant Professor
- Sex
- Male
- Birth date
- 1978-05
- KAKEN ID
- 60451697
- URL
- C,(|!|I1|(26|I$4@OK2I102(2}|I| I'-
- Office
- molecular neurobiology, Masu Lab
- Phone
- 81-29-853-3248
- Fax
- 81-29-853-3498
- Research fields
General medical chemistry - Research keywords
brain, neuron, development, brain function - Research projects
Studies on the corticospinal tract functions in a mutant mouse with bilateral projection 2020-04 -- 2023-03 MASU Masayuki JSPS/Grant-in-Aid for Scientific Research(B) 6,760,000Yen Genetic analysis of a mutant mouse with motor axon defects 2020-04 -- 2023-03 KEINO-MASU Kazuko JSPS/Grant-in-Aid for Scientific Research(C) 1,820,000Yen Identification of corticospinal axon branching factor genes 2003-04 -- 2006-03 Takuya OKADA Japan Society of for the Promotion of Science/Grant-in-Aid for JSPS Fellows 2,700,000Yen - Career history
2007-04 -- 2010-03 University of TsukubaGraduate School of Comprehensive Human Sciencespostdoctoral fellow 2010-04 -- 2011-03 University of TsukubaGraduate School of Comprehensive Human SciencesAssistant Professor 2011-04 -- (current) University of TsukubaFaculty of MedicineAssistant Professor - Academic background
2001-04 -- 2007-03 University of Tsukuba Graduate School of Comprehensive Human Sciences Kansei, Behavioral and Brain Sciences 1997-04 -- 2001-03 Tokyo Institute of Technology School of Bioscience and Biotechnology 生命理学科 - Degree
2007-03 Ph.D. University of Tsukuba 2001-03 B.S. Tokyo Institute of Technology - Academic societies
2010-10 -- (current) Society for Neuroscience 2008-08 -- (current) THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH 2004-08 -- (current) THE JAPAN NEUROSCIENCE SOCIETY - Honors & Awards
2009-09 つくば医科学研究奨励賞 2008-08 Best Poster Award, The Japanese Society of Carbohydrate Research Meeting 2007-03 筑波大学大学院人間総合科学研究科長賞 - Articles
- Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E2 and D2
L. Huang Z.; M. Qu W.; Eguchi N.; Chu M.; Okada T.; ...
Sleep and Biological Rhythms/2(1)/pp.S21-S22, 2004-05 - Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain
Tsuji Yusuke; Kerever Aurelien; Furukawa Toshiki; Kamagat...
MAGNETIC RESONANCE IMAGING/88/pp.123-131, 2022-05 - Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
Takahashi Aki; Durand-de Cuttoli Romain; Flanigan Megh...
NATURE COMMUNICATIONS/13(1)/p.4039, 2022-07-21 - Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
Takahashi Aki; Durand-de Cuttoli Romain; Flanigan Megh...
Nature communications/13(1)/p.4039, 2022-07-21 - Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
Takahashi Aki; Durand-de Cuttoli Romain; Flanigan Megh...
Nature communications/13(1)/p.4039, 2022-07-21 - 錐体路の形成と発達
桝 正幸; 桝 和子; 岡田 拓也
脳神経内科/95(1)/pp.7-15, 2021-07 - Expression of heparan sulfate endosulfatases in the adult mouse brain : Co-expression of Sulf1 and dopamine D1/D2 receptors
Miya Ken; Keino-Masu Kazuko; Okada Takuya; Kobayashi Ken...
Frontiers in Neuroanatomy/15/p.726718, 2021-08 - Abnormal pyramidal decussation and bilateral projection of the corticospinal tract axons in mice lacking the heparan sulfate endosulfatases, Sulf1 and Sulf2
Aizawa Satoshi; Okada Takuya; Keino-Masu Kazuko; Doan Tr...
FRONTIERS IN MOLECULAR NEUROSCIENCE/12/p.333, 2020-01 - Desulfation of heparin sulfate plays a Ley role in corticospinal tract formation
岡田 拓也; 桝和子
Journal of Clinical and Experimental Medicine/pp.234-236, 2018-07 - Data for 3D reconstruction of the corticospinal tract in the wild-type and Semaphorin 6A knockout adult brain
Okada Takuya; Keino-Masu Kazuko; Suto Fumikazu; Mitchell ...
Data in Brief/23/p.103718, 2019 - Remarkable complexity and variability of corticospinal tract defects in adult Semaphorin 6A knockout mice
Okada Takuya; Keino-Masu Kazuko; Suto Fumikazu; Mitchell ...
Brain research/1710/pp.209-219, 2018-12 - Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation
Okada Takuya; Keino-Masu Kazuko; Nagamine Satoshi; Kameta...
Scientific reports/7(1), 2017-10 - A unique mouse model for investigating the properties of amyotrophic lateral sclerosis-associated protein TDP-43, by in utero electroporation
Megumi Akamatsu; Takuma Hiroshi; Takenari Yamashita; Takuya ...
NEUROSCIENCE RESEARCH/77(4)/pp.234-241, 2013-12 - Heparan sulfate endosulfatases are required for normal brain development
Masu M.; Okada T.; Nagamine S.; Keino-Masu K.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE/26(8)/pp.832-832, 2008-12 - Organ-specific Sulfation Patterns of Heparan Sulfate Generated by Extracellular Sulfatases Sulf1 and Sulf2 in Mice
Nagamine Satoshi; Tamba Michiko; Ishimine Hisako; Araki ...
JOURNAL OF BIOLOGICAL CHEMISTRY/287(12)/pp.9579-9590, 2012-03 - Different effects of SulfFP1 and SulfFP2 electroporation in rescuing axon guidance defects in SulfFP double mutant mice
Okada Takuya; Keino-Masu Kazuko; Nagamine Satoshi; Kunita...
NEUROSCIENCE RESEARCH/65(Suppl. 1)/pp.0-0, 2009-01 - Expression of glypican and syndecan genes in the mouse embryonic brain
Masu Masayuki; Murakami Saori; Okada Takuya; Keino-Masu ...
NEUROSCIENCE RESEARCH/61(Suppl. 1)/pp.0-0, 2008-01 - Restoration of axon guidance defects in SulfFP-deficient mice by introducing exogenous SulfFPs
Okada Takuya; Keino-Masu Kazuko; Nagamine Satoshi; Kunita...
NEUROSCIENCE RESEARCH/61(Suppl. 1)/pp.0-0, 2008-01 - Migration and nucleogenesis of mouse precerebellar neurons visualized by in utero electroportion of a green fluorescent protein gene (vol 57, pg 40, 2007)
Okada Takuya; Keino-Masu Kazuko; Masu Masayuki
NEUROSCIENCE RESEARCH/58(1)/pp.101-101, 2007-05 - The origin and development of the precerebellar neurons in the spinal trigeminal nucleus
Okada Takuya; Keino-Masu Kazuko; Masu Masayuki
NEUROSCIENCE RESEARCH/58(Suppl. 1)/pp.0-0, 2007-01 - Migration and nucleogenesis of mouse precerebellar neurons visualized by in utero electroporation of a green fluorescent protein gene
Okada Takuya; Keino-Masu Kazuko; Masu Masayuki
NEUROSCIENCE RESEARCH/57(1)/pp.40-49, 2007-01 - Migration and nucleogenesis of mouse precerebellar neurons visualized by in utero electroporation of a green fluorescent protein gene.
Okada T; Keino-Masu K; Masu M.
Neurosci. Res./57/p.40-49, 2007-01 - Heparan sulfate 6-O-endosulfatases are required for normal brain development
Okada Takuya; Nagamine Satoshi; Keino-Masu Kazuko; Ohto ...
NEUROSCIENCE RESEARCH/55(Suppl. 1)/pp.0-0, 2006-01
- Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E2 and D2
- Books
- Studies on autotaxin signaling in endocytic vesicle biogenesis and embryonic development using whole embryo culture and electroporation.
Masu; M.; Koike; S.; Okada; T.; and Keino-Masu; K.; +岡田 拓也
Lysophospholipid Receptors: Signaling and Biochemistry. John Wiley & Son Inc. Hoboken, NJ, USA., 2012-01
- Studies on autotaxin signaling in endocytic vesicle biogenesis and embryonic development using whole embryo culture and electroporation.
- Conference, etc.
- Extracellular sugar modification regulates neuronal signaling in the nucleus accumbens
MASU Masayuki; Miya Ken; Keino-Masu Kazuko; Okada Tak...
日本生理学会第100回記念大会/2023-03-16 - Roles of a heparan sulfate endosulfatase Sulf1 in locomotor activity changes induced by chemogenetic activation of nucleus accumbens neurons
菊池美里; 岡田拓也; 宮顕; 桝和子; 小林憲太; 桝正幸
第47回日本神経科学大会/2024-07-25 - Role of a heparan sulfate endosulfatase Sulf1 in the regulation of spontaneous locomotor activity by the nucleus accumbens
Kikuchi Misato; Okada Takuya; Miya Ken; Keino-Masu Ka...
Tsukuba conference 2023/2023-09-26 - Role of a heparan sulfate endosulfatase Sulf1 in the regulation of spontaneous locomotor activity by the nucleus accumbens
菊池美里; 岡田拓也; 宮顕; 桝和子; 小林憲太; 桝正幸
第46回日本神経科学大会/2023-08-02 - Involvement the lateral habenul–dorsal raphe nucleus–ventral tegmental area projection in social instigation-heightened aggression in male mice
Takahashi Aki
Neuroscience 2021/2021-11-08--2021-11-11 - Sulf1/2 double-knockout mice show the tendency not to lose in the tube test
Keino-Masu Kazuko; Okada Takuya; Hashimoto Sayaka; Masu ...
第43回日本神経科学大会/2020-07 - Developmental defects of the habenula-interpeduncular circuit in double knockout mice for heparan sulfate endosulfatases Sulf1/2
Hashimoto Sayaka; Okada Takuya; Miya Ken; Keino-Masu Kaz...
第41回日本神経科学大会/2018-07 - Desulfation of heparan sulfate is required for corticospinal tract formation
Masu Masayuki; Okada Takuya; Nagamine Satoshi; Kametani ...
第40回日本神経科学学会大会/2017-07 - Glutamatergic projection from the lateral habenula to the dorsal raphe nucleus escalates aggressive behavior of male mice.
Takahashi Aki; Flanigan Meghan E; Tsunematsu Tomomi; Al...
The 44th Annual Meeting of the Japan Neuroscience Society/The 1st CJK International Meeting/2021-07-28--2021-07-31 - へパラン硫酸エンドスルファターゼSulf1/2欠損マウスにおける皮質脊髄路の両側性投射と運動制御
岡田 拓也; 加藤 鞠花; 相澤 哲史; 桝 和子; Doan Tri; 小金澤 禎史; 玉岡 晃; 桝 正幸
第43回日本神経科学大会/2020-07-29--2020-07-31 - Bilateral projection and motor control of the corticospinal tract in mice lacking the heparan sulfate endosulfatases Sulf1/2
Okada Takuya
第43回日本神経科学大会/2020-07-29--2020-08-01 - Essential roles of heparan sulfate endosulfatases, Sulf1 and Sulf2, in functional corticospinal tract formation
Okada Takuya; Aizawa Satoshi; Keino-Masu Kazuko; Kuppevel...
Proteoglycans 2019/2019-09-29--2019-10-03 - Abnormal trajectories of the corticospinal tract and motor dysfunction in mice lacking heparan sulfate endosulfatases Sulf1/2
Aizawa Satoshi; Okada Takuya; Keino-Masu Kazuko; Tamaoka ...
第42回日本神経科学大会/2019-07-25--2019-07-28 - Heparan sulfate endosulfatases, Sulf1 and Sulf2, are required for habenula circuit development
Hashimoto Sayaka; Okada Takuya; Keino-Masu Kazuko; Masu ...
第40回日本神経科学大会/2017-07-20--2017-07-23
- Extracellular sugar modification regulates neuronal signaling in the nucleus accumbens
- Teaching
2024-04 -- 2024-07 Biochemistry and Molecular Biology University of Tsukuba. 2024-10 -- 2025-02 English for Specialized Subjects G University of Tsukuba. 2024-04 -- 2024-08 English for Specialized Subjects G University of Tsukuba. 2024-05 -- 2024-08 Medical Biochemistry University of Tsukuba. 2024-04 -- 2024-07 Topics in Biochemistry University of Tsukuba. 2024-04 -- 2024-07 Pharmacology University of Tsukuba. 2023-10 -- 2024-02 English for Specialized Subjects G University of Tsukuba. 2023-04 -- 2023-08 English for Specialized Subjects G University of Tsukuba. 2023-04 -- 2023-07 Topics in Biochemistry University of Tsukuba. 2023-05 -- 2023-08 Medical Biochemistry University of Tsukuba. more... - Other educational activities
2020-04 -- (current) 医学類M1クラス担任 筑波大学 - Talks
- Heparan sulfate endosulfatases are required for normal brain development
Masu M.; Okada T.; Nagamine S.; 桝 和子
17th Biennial meeting of the Internatioal Society for Developmental Neuroscience/2008-06-01 - Heparan Sulfate Modification by Endosulfatases is Required for Cortical Axon Guidance
Masayuki Masu; Takuya Okada; Satoshi Nagamine; Tatsuyuki ...
1st international symposium/ 59th NIBB conferences “Neocortical organization”/2012-03-10 - ヘパラン硫酸糖鎖による軸索ガイダンス制御機構
桝正幸; 岡田拓也; 長嶺聖史; 大戸達之; 亀谷富由樹; 長谷川成人; ; 國田智; 高橋智; 桝和子
第34回日本神経科学学会大会/2011-09-14 - Heparan sulfate 6-Oendosulfatases are required for neural network formation.
T. Okada; K. Keino-Masu; S. Nagamine; S. Kunita; S. Taka...
The 40th Annual meeting of the Society for Neuroscience/2010-11-13 - マウス胎児脳におけるヘパラン硫酸多様性の検出
岡田拓也; 桝和子; 長嶺聖史; 國田智; 高橋智; Arie Oosterhof; Toin Kuppevelt; 桝正幸
第33回日本神経科学学会大会・第53回日本神経化学会大会・第20回日本神経回路学会大会/2010-09-02 - 電気穿孔法で導入したSulfFP1とSulfFP2でSulfFP欠損マウスの表現型回復の効果が異なる
岡田拓也; 桝和子; 長嶺聖史; 國田智; 高橋智; 桝正幸
第32回日本神経科学大会/2009-09-16 - ヘパラン硫酸エンドスルファターゼSulfFP1/2導入による神経軸索走行回復効果
岡田拓也; 桝和子; 長嶺聖史; 國田智; 高橋智; 桝正幸
第29回日本糖質学会年会/2009-09-09 - ヘパラン硫酸6-O-エンドスルファターゼは正常な神経回路形成に必要である
岡田拓也
日本生化学会関東支部例会/2009-06-20 - 神経発生におけるヘパラン硫酸エンドスルファターゼの役割
桝正幸; 岡田拓也; 長嶺聖史; 塩見健輔; 丹波道子; 石嶺久子; 大戸達之; 國田智; 高橋智; 桝和子
第51回日本神経化学会大会/2008-09-11 - エンドスルファターゼによるヘパラン硫酸リモデリングと生体シグナル制御
桝和子; 岡田拓也; 塩見健輔; 長嶺聖史; 丹波道子; 石嶺久子; 大戸達之; 國田智; 高橋智; 桝正幸
第28回日本糖質学会年会/2008-08-18 - ヘパラン硫酸6-O-エンドスルファターゼは正常な神経回路形成に必要である
岡田拓也; 桝和子; 長嶺聖史; 國田智; 高橋智; 桝正幸
第28回日本糖質学会年会/2008-08-18 - SulfFP欠損マウスの表現型回復実験
岡田拓也; 桝和子; 長嶺聖史; 國田智; 高橋智; 桝正幸
第31回日本神経科学大会/2008-07-09 - グリピカンとシンデカン遺伝子のマウス胎児脳における発現
桝正幸; 村上さおり; 岡田拓也; 桝和子
第31回日本神経科学大会/2008-07-09 - Electroporation-based analysis of signaling molecules regulating migration and necleogenesis
Takuya Okada; Kazuko Keino-Masu; Masayuki Masu.
The 37th Annual meeting of the Society for Neuroscience/2007-11-03 - 小脳に投射する三叉神経脊髄路核神経細胞の起源と発生
岡田拓也; 桝和子; 桝正幸
第30回日本神経科学大会・第50回日本神経化学会大会・第17回日本神経回路学会大会/2007-09-10 - ヘパラン硫酸修飾酵素SulfFPによる形態形成制御
塩見健輔; 長嶺聖史; 岡田拓也; 桝和子; 桝正幸
第40回日本発生生物学会・第59回日本細胞生物学会合同大会 ミニシンポジウム「細胞外マトリックスによる細胞運命制御」/2007-05-28 - Migration and nucleogenesis of mouse precerebellar neurons visualized by in utero electroporation of a green fluorescent protein gene
Takuya Okada; Kazuko Keino-Masu; and Masayuki Masu
The 8th AEARU Joint Workshop on Life Science/2006-11-04 - ヘパラン硫酸6-エンドスルファターゼは脳の正常な発生に必要である
岡田拓也; 長嶺聖史; 桝和子; 大戸達之; 國田智; 高橋智; 桝正幸
第29回日本神経科学大会/2006-07-19 - マイクロアレイ法を用いた側枝形成因子の解析
岡田拓也; 桝和子; 塩見健輔; 桝正幸
第27回日本神経科学大会・第47回日本神経化学会大会/2004-09-21
- Heparan sulfate endosulfatases are required for normal brain development
- University Management
2020-04 -- (current) 医学学位プログラム教務委員会 委員(キャリアパス・セミナー担当) 2019-04 -- 2020-03 生命システム医学専攻教務委員会 委員(イニシエーション・セミナー担当)
(Last updated: 2024-09-13)