Dong-Zhu Xu

Affiliation
Institute of Medicine
Official title
Associate Professor
ORCID
0000-0001-6507-1959
KAKEN ID
20616651
Email
=;8'21*FUQ,8O('8\;8"'21*=+8FUQ0'O768.8%$O$&O-3\
Other affiliation
Indiana University School of Medicine (USA) Division of Cardiovascular Medicine
Research fields
Cardiovascular medicine
Research projects
AMED橋渡し研究戦略的推進プログラム(シーズA)2021-04 -- 2022-03Japan Agency for Medical Research and Development (AMED)/1,000,000Yen
The role of Nicotinamide phosphoribosyltransferase (Nampt) in atrial fibrillation(Fostering Joint International Research)2016 -- 2018DONGZHU XUMinistry of Education, Culture, Sports, Science and Technology, Japan/Fund for the Promotion of Joint International Research : Fostering Joint International Research14,300,000Yen
心房細動の発症におけるNampt役割の解明2015 -- 2016許 東洙Japan Society for the Promotion of Science/Grant-in-Aid for Young Scientists(B)4,030,000Yen
不整脈の発症機序解明と治療 -- (current)/
肥満による心房細動発症機序の解明2012 -- 2013許 東洙Japan Society of for the Promotion of Science/若手研究(B)4,300,000Yen
Career history
2023-12 -- (current)Indiana University School of MedicineDivision of Cardiovascular MedicineResearch Faulty
2018-07 -- (current)筑波大学医学医療系 循環器内科准教授
2015-10 -- 2018-06Indiana University School of MedicineKrannert Institute of CardiologyResearch fellow
2011-04 -- 2017-12University of Tsukuba医学医療系 循環器内科助教
1999 -- 2001中国吉林省延吉市立病院内科医師
Academic background
2007-04 -- 2011-03University of Tsukuba Graduate School, Division of Medicine Cardiovascular Division Institute of Clinical Medicine
Degree
2011-03Ph.D.University of Tsukuba
Academic societies
2012-08 -- (current)日本心臓電気生理学会
2007 -- (current)THE JAPANESE CIRCULATION SOCIETY
2005-08 -- (current)Japan Primary Care Association
Articles
Books
  • Directing stem cell fate using plant extracts and their bioactive compounds
    Isoda Hiroko; Szele Francis G.; Zheng Yun-Wen; Xu Don...
    Directing stem cell fate using plant extracts and their bioactive compounds/FRONTIERS MEDIA SA, 2023
  • Atrial fibrillation rat model induced by transvenous catheter pacing and PPAR-γ activator as upstream therapy for age-related atrial fibrillation
    許 東洙
    2011-03
Conference, etc.
  • Deletion of EIF4EBP3 prevents heart failure progression through maintaining mitochondrial function
    Yuan Zixun; Murakoshi Nobuyuki; Xu Dongzhu; Tajiri Ka...
    第87回日本循環器学会学術集会/2023-03-10--2023-03-12
  • Molecular Mechanisms of a Newly Established Inherited Arrhythmia Mouse Model and Its Clinical Application
    岡部 雄太; 村越 伸行; 井藤 葉子; 三好 千香; 船戸 弘正; 石井 光一郎; 井上 華; 村...
    第87回日本循環器学会学術集会/2023-03-10--2023-03-12
  • The effect of BET inhibitor on pathogenesis of atrial fibrillation
    Song Zonghu; Murakoshi Nobuyuki; Xu Dongzhu; Murakata ...
    第87回日本循環器学会学術集会/2023-03-10--2023-03-12
  • The therapeutic effect of BET inhibitor on atrial fibrillation
    Song Zonghu; Murakoshi Nobuyuki; Xu Dongzhu; Murakata ...
    Cardiovascular Metabolic Week (CVMW) 2022/2022-12-17--2022-12-17
  • Heart Failure related Potential Key Molecule was Identified by Human RNA-sequencing datasets and Mouse Model
    Yuan Zixun; Murakoshi Nobuyuki; Murakoshi Nobuyuki; Xu...
    第26回日本心不全学会/2022-10-21--2022-10-23
  • Underlying mechanisms Related with Heart Failure are Identified by Meta-Analysis and Consensus Analysis of RNA-sequencing
    Yuan Zixun; Murakoshi Nobuyuki; Xu Dongzhu; Li Siqi; ...
    第26回日本心不全学会/2022-10-21--2022-10-23
  • Generation and Analyses of iPSC-derived Cardiomyocytes from a Dilated Phase Hypertrophic Cardiomyopathic Patient Carrying MYBPC3 Frameshift Mutation
    Mori Haruka; Murakoshi Nobuyuki; Shimoda Yuzuno; Xu D...
    第26回日本心不全学会/2022-10-21--2022-10-23
  • Heart Failure-related Potential Molecule Identified by Bioinformatics analysis and Mouse Model
    袁 梓勛; 村越 伸行; 許 東洙; 田尻 和子; 李 思琪; 村方 好子; 岡部 雄太; 宋 宗虎...
    第8回日本心筋症研究会/2022-05-14--2022-05-14
  • 4E-BP3 Deficiency Ameliorates the Development of Autoimmune Myocarditis in Mice.
    SIQI LI; 許 東洙; Kazuko Tajiri; Nobuyuki Murakoshi
    NORTH AMERICAN MEETING OF THE INTERNATIONAL SOCIETY OF HEART RESEARCH/2023-06-26--2023-06-30
  • Establishment of induced pluripotent stem cell lines derived from dilated cardiomyopathic patients with LMNA mutations and generation of pathological models
    Shimoda Yuzuno; Murakoshi Nobuyuki; Mori Haruka; Kobayash...
    CiRA 2022 International Symposium/2022-02-16--2022-02-16
  • Cardiomyopathy-Related Hub Genes and Upstream Regulators by Meta-analysis of RNA-Sequencing datasets
    袁 梓勛; 村越 伸行; 許 東洙; 田尻 和子; 岡部 雄太; 李 思琪; 馮 鐸; 米林 沙織; 青沼 和宏...
    第86回日本循環器学会学術集会/2022-03-13--2022-03-13
  • LMNA遺伝子変異に起因する拡張型心筋症患者由来iPS細胞の樹立と病態モデルの作製
    下田 柚須乃; 村越 伸行; 森 遥香; 小林 和真; 田尻 和子; 許 東洙; 佐藤 伊織; 辺見 康子; 林 ...
    第21回日本再生医療学会総会/2022-03-17--2022-03-17
  • Natural compound Isorhamnetin Inhibits Angiotensin II-induced Atrial Fibrillation Vulnerability Through Electrophysiological and Structural Reverse Remodeling in Mice
    Aonuma Kazuhiro; Dong-Zhu Xu; Murakoshi Nobuyuki; Tajiri...
    THE 85TH ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY/2021-03-26--2021-03-28
  • Isorhamnetin Reverses Angiotensin II-induced Atrial Fibrillation Vulnerability Through Electrophysiological and Structural Reverse Remodeling in Mice
    Dong-Zhu Xu; Aonuma Kazuhiro; Murakoshi Nobuyuki; Tajiri...
    American Heart Association Scientific Sessions 2020/2020-11-13--2020-11-17
  • MAIR-II deficiency ameliorates cardiac remodeling post-myocardial infarction by suppressing TLR9-mediated pro-inflammatory macrophage activation
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; Xu ...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • The role of immune checkpoints in the development of autoimmune myocarditis in mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • 4E-BP3 deficiency attenuates cardiac inflammation in mice with experimental autoimmune myocarditis.
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • 4E-BP3 deficiency protects against autoimmune myocarditis in mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第24回日本心不全学会学術集会/2020-10-15--2020-10-17
  • 4E-BP3 Deficiency Attenuates Cardiac Inflammation in Mice with Experimental Autoimmune Myocarditis
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第85回日本循環器学会学術集会/2021-03-26--2021-03-28
  • PD-L2 Protects Against Autoreactive CD4+ T-cell Expansion and Inflammation in Autoimmune Myocarditis in Mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Ok...
    CVMW2020/2021-03-12--2021-03-13
  • PD-L2 Immune Checkpoint Protein Protects Against Autoimmune Myocarditis in Mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第85回日本循環器学会学術集会/2021-03-26--2021-03-28
  • 翻訳開始制御分子EIF4EBP3はマウス自己免疫性心筋炎を増悪する
    Li Siqi; 田尻 和子; 米林沙織; Zixun Yuan; Duo Feng; 岡部 雄太; 井上慶子; 青沼...
    第3回日本腫瘍循環器学会学術集会/2020-09-11--2020-09-12
  • 4E-BP3 deficiency ameliorates autoimmune myocarditis in mice
    Siqi Li; 田尻 和子; 米林沙織; Zixun Yuan; 馮 鐸; 岡部雄太; 東洙 許; 村越 伸行; 家田真樹
    第6回日本心筋症研究会/2020-08-21--2020-08-31
  • MAIR-II deficiency improves cardiac remodeling by suppressing TLR9-mediated pro-inflammatory macrophage activation post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; Xu ...
    第84回日本循環器学会学術集会/2020-07-27--2020-08-02
  • Impaired Peripheral Immune Tolerance to Cardiac Myosin Leads to Chronic Myocardial Inflammation
    Tajiri Kazuko; Imanaka-Yoshida Kyoko; Hiroe Michiaki; Li ...
    第84回日本循環器学会学術集会/2020-07-27--2020-08-02
  • more...
Teaching
2023-10 -- 2024-02Doctor's Internship IIUniversity of Tsukuba.
2023-04 -- 2023-08Doctor's Internship IIUniversity of Tsukuba.
2023-10 -- 2024-03Life Science Innovation Master's Special Seminar II FallUniversity of Tsukuba.
2023-10 -- 2024-03Life Science Innovation Doctor's Special Seminar III FallUniversity of Tsukuba.
2023-05 -- 2023-06Advances in Cellular RegulationUniversity of Tsukuba.
2023-04 -- 2023-09Life Science Innovation Doctor's Special Seminar I SpringUniversity of Tsukuba.
2023-04 -- 2023-09Life Science Innovation Doctor's Special Seminar III SpringUniversity of Tsukuba.
2023-10 -- 2024-03Life Science Innovation Master's Special Seminar I FallUniversity of Tsukuba.
2023-04 -- 2023-09Life Science Innovation Master's Special Seminar I SpringUniversity of Tsukuba.
2023-10 -- 2024-02Doctor's Internship IUniversity of Tsukuba.
more...
Talks
  • 『心筋梗塞後の心室頻拍に対するアブレーション治療』(Catheter ablation of postinfarction ventricular tachycardia)
    DongZhu Xu; +許 東洙
    第22回長城国際心臓病学会 アジア太平洋心臓大会/2011-10-15

(Last updated: 2024-01-13)