Dong-Zhu Xu

Affiliation
Faculty of Medicine
Official title
Associate Professor
ORCID
0000-0001-6507-1959
Email
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Other affiliation
University of Tsukuba Department of Cardiology, Faculty of MedicineAssociated Professor
Research fields
Cardiovascular medicine
Research projects
AMED橋渡し研究戦略的推進プログラム(シーズA)2021-04 -- 2022-03Japan Agency for Medical Research and Development (AMED)/1,000,000Yen
The role of Nicotinamide phosphoribosyltransferase (Nampt) in atrial fibrillation(Fostering Joint International Research)2016 -- 2018DONGZHU XUMinistry of Education, Culture, Sports, Science and Technology, Japan/Fund for the Promotion of Joint International Research : Fostering Joint International Research14,300,000Yen
心房細動の発症におけるNampt役割の解明2015 -- 2016許　東洙Japan Society for the Promotion of Science/Grant-in-Aid for Young Scientists(B)4,030,000Yen
不整脈の発症機序解明と治療 -- (current)/
肥満による心房細動発症機序の解明2012 -- 2013許　東洙Japan Society of for the Promotion of Science/若手研究(B)4,300,000Yen
Career history
2018-07 -- (current)筑波大学医学医療系　循環器内科准教授
2015-10 -- 2018-06Indiana University School of MedicineKrannert Institute of CardiologyResearch fellow
2011-04 -- 2017-12University of Tsukuba医学医療系　循環器内科助教
1999 -- 2001中国吉林省延吉市立病院内科医師
Academic background
2007-04 -- 2011-03University of Tsukuba Graduate School, Division of Medicine Cardiovascular Division Institute of Clinical Medicine
Degree
2011-03Ph.D.University of Tsukuba
Academic societies
2012-08 -- (current)日本心臓電気生理学会
2007 -- (current)THE JAPANESE CIRCULATION SOCIETY
2005-08 -- (current)Japan Primary Care Association
Articles
Books
  • Atrial fibrillation rat model induced by transvenous　catheter pacing and PPAR-γ activator as upstream therapy for age-related atrial fibrillation
    許 東洙
    2011-03
Conference, etc.
  • Establishment of induced pluripotent stem cell lines derived from dilated cardiomyopathic patients with LMNA mutations and generation of pathological models
    Shimoda Yuzuno; Murakoshi Nobuyuki; Mori Haruka; Kobayash...
    CiRA 2022 International Symposium/2022-02-16--2022-02-16
  • Cardiomyopathy-Related Hub Genes and Upstream Regulators by Meta-analysis of RNA-Sequencing datasets
    袁 梓勛; 村越 伸行; 許 東洙; 田尻 和子; 岡部 雄太; 李 思琪; 馮 鐸; 米林 沙織; 青沼 和宏...
    第86回日本循環器学会学術集会/2022-03-13--2022-03-13
  • LMNA遺伝子変異に起因する拡張型心筋症患者由来iPS細胞の樹立と病態モデルの作製
    下田 柚須乃; 村越 伸行; 森 遥香; 小林 和真; 田尻 和子; 許 東洙; 佐藤 伊織; 辺見 康子; 林 ...
    第21回日本再生医療学会総会/2022-03-17--2022-03-17
  • Natural compound Isorhamnetin Inhibits Angiotensin II-induced Atrial Fibrillation Vulnerability Through Electrophysiological and Structural Reverse Remodeling in Mice
    Aonuma Kazuhiro; Dong-Zhu Xu; Murakoshi Nobuyuki; Tajiri...
    THE 85TH ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY/2021-03-26--2021-03-28
  • Isorhamnetin Reverses Angiotensin II-induced Atrial Fibrillation Vulnerability Through Electrophysiological and Structural Reverse Remodeling in Mice
    Dong-Zhu Xu; Aonuma Kazuhiro; Murakoshi Nobuyuki; Tajiri...
    American Heart Association Scientific Sessions 2020/2020-11-13--2020-11-17
  • MAIR-II deficiency ameliorates cardiac remodeling post-myocardial infarction by suppressing TLR9-mediated pro-inflammatory macrophage activation
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; Xu ...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • The role of immune checkpoints in the development of autoimmune myocarditis in mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • 4E-BP3 deficiency attenuates cardiac inflammation in mice with experimental autoimmune myocarditis.
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    Tsukuba Global Science Week 2020/2020-09-28--2020-09-30
  • 4E-BP3 deficiency protects against autoimmune myocarditis in mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第24回日本心不全学会学術集会/2020-10-15--2020-10-17
  • 4E-BP3 Deficiency Attenuates Cardiac Inflammation in Mice with Experimental Autoimmune Myocarditis
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第85回日本循環器学会学術集会/2021-03-26--2021-03-28
  • PD-L2 Protects Against Autoreactive CD4+ T-cell Expansion and Inflammation in Autoimmune Myocarditis in Mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Ok...
    CVMW2020/2021-03-12--2021-03-13
  • PD-L2 Immune Checkpoint Protein Protects Against Autoimmune Myocarditis in Mice
    Li Siqi; Tajiri Kazuko; Yonebayashi Saori; Yuan Zixun; Fe...
    第85回日本循環器学会学術集会/2021-03-26--2021-03-28
  • 翻訳開始制御分子EIF4EBP3はマウス自己免疫性心筋炎を増悪する
    Li Siqi; 田尻 和子; 米林沙織; Zixun Yuan; Duo Feng; 岡部 雄太; 井上慶子; 青沼...
    第3回日本腫瘍循環器学会学術集会/2020-09-11--2020-09-12
  • 4E-BP3 deficiency ameliorates autoimmune myocarditis in mice
    Siqi Li; 田尻 和子; 米林沙織; Zixun Yuan; 馮　鐸; 岡部雄太; 東洙 許; 村越　伸行; 家田真樹
    第6回日本心筋症研究会/2020-08-21--2020-08-31
  • MAIR-II deficiency improves cardiac remodeling by suppressing TLR9-mediated pro-inflammatory macrophage activation post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; Xu ...
    第84回日本循環器学会学術集会/2020-07-27--2020-08-02
  • Impaired Peripheral Immune Tolerance to Cardiac Myosin Leads to Chronic Myocardial Inflammation
    Tajiri Kazuko; Imanaka-Yoshida Kyoko; Hiroe Michiaki; Li ...
    第84回日本循環器学会学術集会/2020-07-27--2020-08-02
  • Direct reprogramming of fibroblasts into cardiac mesoderm by defined factors.
    Sadahiro Taketaro; Isomi Mari; Tamura Fumiya; Murakoshi ...
    2019 XXIII ISHR WORLD CONGRESS/2019-06-03
  • Deletion of the nicotinamide phosphoribosyltransferase (Nampt) and high-fat diet increases atrial fibrillation inducibility through altering calcium handling pathway
    Duo Feng; 東洙 許; Murakoshi Nobuyuki; Tajiri Kazuko; Yoneba...
    CVMW2019 心血管代謝週間/2019-12-13--2019-12-14
  • MAIR-II deficiency ameliorates adverse cardiac remodeling post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; 東洙 ...
    CVMW2019 心血管代謝週間/2019-12-13--2019-12-14
  • MAIR-II deficiency promotes favorable cardiac remodeling post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; 東洙 ...
    Tsukuba Conference 2019/2019-10-02--2019-10-04
  • MAIR-II deficiency prevents exacerbated cardiac inflammation and fibrosis post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; 東洙 ...
    The 3rd JCS Council Forum on Basic CardioVasculr Research/2019-09-06--2019-09-08
  • Prognostic Impact of Atrial Fibrillation on Cardiac and Stroke Death in the Ibaraki Prefectural Health Study.
    Murakoshi Nobuyuki; Sairenchi Toshimi; Xu; Igarashi; Irie ...
    American Heart Association Scientific Sessions 2018/2018-11-10--2018-11-13
  • MAIR-II deficiency promotes anti-inflammatory macrophage infiltration preventing cardiac dysfunction post-myocardial infarction
    Yonebayashi Saori; Tajiri Kazuko; Murakoshi Nobuyuki; 東洙 ...
    2019 XXIII ISHR WORLD CONGRESS/2019-06-03--2019-06-06
  • IL-6 Promotes Atrial Autonomic Remodeling Associated with Atrial Fibrillation
    Yamagami Fumi; Tajiri Kazuko; Feng Duo; Rujie Qin; Yonebay...
    2019 XXIII ISHR WORLD CONGRESS/2019-06-03--2019-06-06
  • Neutrophil extracellular trap (NET)-associated elastase delays resolution of acute inflammation via Annexin A1 cleavage in myocardial infarction
    Tajiri Kazuko; Ogura Yukino; Yonebayashi Saori; Siqi Li; ...
    2019 XXIII ISHR WORLD CONGRESS/2019-06-03--2019-06-06
  • more...
Teaching
2022-10 -- 2023-03Doctor's Internship FallUniversity of Tsukuba.
2022-10 -- 2023-03Doctor's Internship Abroad FallUniversity of Tsukuba.
2022-04 -- 2022-08Doctor's Internship IIUniversity of Tsukuba.
2022-10 -- 2023-02Doctor's Internship IIUniversity of Tsukuba.
2022-04 -- 2022-09Doctor's Internship Abroad SpringUniversity of Tsukuba.
2022-04 -- 2022-09Doctor's Internship SpringUniversity of Tsukuba.
2022-04 -- 2022-08Doctor's Internship IUniversity of Tsukuba.
2022-10 -- 2023-02Doctor's Internship IUniversity of Tsukuba.
2022-04 -- 2022-09Life Science Innovation Doctor's Special Seminar I SpringUniversity of Tsukuba.
2022-04 -- 2022-09Life Science Innovation Doctor's Special Seminar II SpringUniversity of Tsukuba.
more...
Talks
  • 『心筋梗塞後の心室頻拍に対するアブレーション治療』（Catheter ablation of postinfarction ventricular tachycardia）
    DongZhu Xu; +許 東洙
    第22回長城国際心臓病学会　アジア太平洋心臓大会/2011-10-15

(Last updated: 2022-11-29)