LAZARUS Michael

Affiliation
Institute of Medicine
Official title
Professor
ORCID
0000-0003-3863-4474
Sex
Male
KAKEN ID
80469650
URL
Email
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Office
International Institute for Integrative Sleep Medicine (WPI-IIIS)
Phone
029-853-3681
Research fields
Neurochemistry/Neuropharmacology
Nerve anatomy/Neuropathology
Neurophysiology / General neuroscience
Research keywords
Single-cell RNA sequencing
Sleep
Remote control of neuronal activity in mice
Optogenetics
Obesity
Hibernation
Appetite
Research projects
Solving the Mystery of Immune Regulation by Sleep2024-03 -- 2025-08LAZARUS MichaelChan Zuckerberg Initiative/Collaborative Pairs Pilot Project Awards (Cycle 2)15,000,000Yen
Gliosomnia and immunity: decoding brain-immune interactions in sleep2023-04 -- 2025-03Michael LAZARUSJapan Society of for the Promotion of Science/Grant-in-Aid for Transformative Research Areas (A) (Public offered research)13,000,000Yen
Understanding the mechanism of sleepiness by exploring mesolimbic glia-neuron interactions2021 -- 2025LAZARUS MichaelJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B)17,030,000Yen
WillDynamics of REM sleep and appetite2019 -- 2020LAZARUS MichaelJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas7,540,000Yen
Neuronal mechanisms of sleep alterations in Parkinson's Disease: A circuit based investigation2018-04 -- 2020-03LAZARUS MichaelJapan Society for the Promotion of Science/Grant-in-Aid for JSPS Fellows2,400,000Yen
Risk of hypothermia for memory function2018 -- 2019LAZARUS MichaelJapan Society for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Areas5,720,000Yen
Will-dynamics of REM sleep and appetite2017-04 -- 2019-03Michael LazarusJapan Society of for the Promotion of Science/Grant-in-Aid for Scientific Research on Innovative Area9,100,000Yen
The role of the nucleus accumbens in regulating slow-wave sleep by motivated behavior2017-04 -- 2021-03Michael LazarusJapan Society of for the Promotion of Science/ Grant-in-Aid for Scientific Research (B)17,290,000Yen
Adenosine A2A receptor optopharmacology in freely behaving mice2016-11 -- 2019-10Michael LazarusThe Naito Foundation/Natural Science Scholarship3,000,000Yen
Integrated analysis of the function of sleep and its regulatory mechanisms using optical technologies2016-10 -- 2021-09Masashi YanagisawaJapan Science and Technology Agency (JST)/JST Basic Research Programs (Core Research for Evolutional Science and Technology :CREST)52,000,000Yen
more...
Career history
2022-03 -- (current)University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS)Professor/Principal Investigator
2013-04 -- 2022-02University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS)Associate Professor/Principal Investigator
2007-09 -- 2013-03Osaka Biosciene InstituteUrade LabResearch Associate
2002-07 -- 2007-08Beth Israel Deaconess Medical Center/Harvard Medical SchoolDepartment of NeurologyInstructor
1999-06 -- 2002-07Osaka Biosciene InstituteHayaishi LabPostdoctoral Associate
Academic background
1990-10 -- 1998-07University of Würzburg Faculty of Chemistry and Food Chemistry
Degree
1998-07PhD (Dr. rer. nat.)University of Würzburg
Academic societies
2001-02 -- (current)Humboldt-Klub Japan
2009-04 -- (current)THE JAPAN NEUROSCIENCE SOCIETY
2009-08 -- (current)THE JAPANESE SOCIETY OF SLEEP RESEARCH
2003-01 -- (current)Society for Neuroscience
2001-02 -- (current)Humboldt Foundation Network
Articles
Books
  • Adenosine A2A receptors and sleep
    Korkutata Mustafa; Lazarus Michael
    ADENOSINE A2A RECEPTOR ANTAGONISTS/ELSEVIER ACADEMIC PRESS INC/pp.155-178, 2023-04-01
  • Adenosinergic Control of Sleep
    Lazarus Michael; Oishi Yo; Landolt Hans-Peter
    Principles and Practice of Sleep Medicine Seventh Edition/pp.452-459, 2021-12
  • Adenosinergic Control of Sleep/Wake Behavior
    Zhou Xuzhao; Lazarus Michael
    HANDBOOK OF SLEEP RESEARCH, VOL 30/ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD/pp.125-136, 2019
Conference, etc.
  • The teleological mystery of sleep - Glioneuronal mechanisms Integrating sleep homeostasis and motivation
    LAZARUS Michael
    SleepWell Research Seminar at University of Helsinki/2025-04-15
  • Why are we sleepy when we are bored? Molecular links between sleep, motivation, and the immune system
    LAZARUS Michael
    UC Davis Seminar/2025-04-17
  • Solving the mystery of immune regulation by sleep
    LAZARUS Michael
    Chan Zuckerberg Intiative – Neuroscience 2025/2025-03-05--2025-03-08
  • The Teleological Mystery of Sleep — Glioneuronal Mechanisms Integrating Sleep Homeostasis and Motivation
    LAZARUS Michael
    CNS 2024– The 17th Annual Meeting of the Chinese Neuroscience Society/2024-09-26--2024-09-29
  • Why are we sleepy when we are bored? Molecular links between sleep and motivation
    LAZARUS Michael
    第38回 日本大脳基底核研究会/2024-08-03--2024-08-04
  • The teleological mystery of sleep ⎯ Glioneuronal mechanisms integrating sleep homeostasis and motivation
    LAZARUS Michael
    Glia Decoding International Symposium/2024-07-27--2024-07-28
  • The neuroglial mechanisms underlying the gating of sleep homeostasis by motivation
    LAZARUS Michael
    NEURO 2024 – The 47th Annual Meeting of the Japan Neuroscience Society/2024-07-24--2024-07-27
  • 睡眠の時空間制御を目指した遠隔操作薬の開発
    斉藤 毅; Koustav Roy; 大谷 凛太朗; 井岡 秀二; Michael Lazarus
    第18回GPCR研究会/2024-05-25--2024-05-26
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    Lazarus Michael
    ERATO UK-Japan Joint Symposium on Circadian Rhythms and Sleep/2024-03-11--2024-03-13
  • The Teleological Mystery of Sleep - Glioneuronal Mechanisms Integrating Sleep Homeostasis and Motivation
    Lazarus Michael
    Gordon Research Conference “Sleep Regulation and Function/2024-03-03--2024-03-08
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    Lazarus Michael
    2023 Oriental International Sleep Medicine Summit Forum Shanghai/2023-12-8--2023-12-10
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    Lazarus Michael
    45th Annual Meeting of Japanese Society of Sleep Research/2023-09-15--2023-09-17
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    Lazarus Michael
    CNS 2023 & CJK 2nd – The 16th Annual Meeting of the Chinese Neuroscience Society & The 2nd CJK International Meeting/2023-10-20--2023-10-25
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    Lazarus Michael
    CNS 2023 & CJK 2nd – The 16th Annual Meeting of the Chinese Neuroscience Society & The 2nd CJK International Meeting/2023-07-27--2023-07-30
  • Why Are We Sleepy When we Are bored? - the Gating of Sleep Homeostasis by Motivation
    Lazarus Michael
    SLEEP 2023 – 37th Meeting of the Associated Sleep Societies/2023-06-03--2023-06-07
  • Decoding the neuronal and glial regulation of sleep homeostasis by motivation in mice
    Lazarus Michael
    CSHA meeting on novel insights into glia function and dysfunction/2023-04-24--2023-04-27
  • Why are we sleepy when we are bored? The gating of sleep homeostasis by motivation
    Lazarus Michael
    IPSA Online, 7th Congress of the International Pediatric Sleep Association (IPSA)/2022-10-27--2022-10-29
  • Molecular mechanisms underlying the gating of sleep homeostasis by motivation
    Lazarus Michael
    The Nineteenth Conference of Peace through Mind/Brain Science/2023-02-21--2023-02-23
  • Opto-chemical control of sleep in the nucleus accumbens using a photocaged adenosine A2A receptor allosteric modulator
    Lazarus Michael
    Photopharmacology III/2021-11-29--2021-11-30
  • Why are we sleepy when bored? - The gating of sleep homeostasis by motivation
    Lazarus Michael
    5th Asian Forum on Chronobiology/2021-07-14--2021-07-19
  • The gating of sleep homeostasis by motivation Why are we sleepy when bored?
    Lazarus Michael
    3rd Congress of the Asian Society of Sleep Medicine/2021-05-16
  • Involvement the lateral habenul–dorsal raphe nucleus–ventral tegmental area projection in social instigation-heightened aggression in male mice
    Takahashi Aki
    Neuroscience 2021/2021-11-08--2021-11-11
  • Glutamatergic projection from the lateral habenula to the dorsal raphe nucleus escalates aggressive behavior of male mice.
    Takahashi Aki; Flanigan Meghan E; Tsunematsu Tomomi; Al...
    The 44th Annual Meeting of the Japan Neuroscience Society/The 1st CJK International Meeting/2021-07-28--2021-07-31
  • The gating of sleep by motivated behavior
    Lazarus M.
    24th Congress of the European-Sleep-Research-Society (ESRS)/2018-09-25--2018-09-28
  • A nucleus accumbens circuit in control of sleep
    Lazarus Michael
    4th International Pediatric Sleep Association Congress/2016-03-10--2016-03-13
  • more...
Teaching
2024-04 -- 2024-08Special Research in Humanics IIIaUniversity of Tsukuba.
2024-10 -- 2025-02Special Seminars in Humanics IIIbUniversity of Tsukuba.
2024-10 -- 2025-02Basic Experiments in Human BiologyUniversity of Tsukuba.
2024-10 -- 2025-02Special Lecture in Kansei , Behav ioral and Brain Sciences 4University of Tsukuba.
2024-04 -- 2024-08Special Lecture in Kansei , Behav ioral and Brain Sciences 4University of Tsukuba.
2024-04 -- 2024-08Special Seminars in Human Biology IUniversity of Tsukuba.
2024-10 -- 2025-02Special Lectures in Humanics IIIbUniversity of Tsukuba.
2024-04 -- 2024-08Special Lectures in Humanics IIIaUniversity of Tsukuba.
2024-04 -- 2024-08Special Seminars in Humanics IIIaUniversity of Tsukuba.
2024-10 -- 2025-02Special Lecture in Kansei , Behavioral and Brain Sciences 6University of Tsukuba.
more...
Talks
  • Glioneuronal mechanisms integrating sleep homeostasis and motivation
    LAZARUS Michael
    ERATO UK-Japan Joint Symposium on Circadian Rhythms and Sleep/2024-04-29--2024-04-29
  • Why are we sleepy when we are bored? The gating of sleep homeostasis by motivation
    Lazarus Michael
    Technical University Dresden CMCB Life Sciences Seminar/2022-09-22
  • The gating of sleep homeostasis by motivation
    Lazarus Michael
    大阪大学第8回子どものこころの 分子統御機構研究センター連続セミナー/2021-12-14
  • Why are we sleepy when we are bored? The gating of sleep homeostasis by motivation
    Lazarus Michael
    大阪大学蛋白質研究所セミナー “多様なドーパミン神経伝達から脳を探る”/2021-12-13
Professional activities
2023-04 -- 2026-03The Japan Neuroscience SocietyCouncilor
Message
We are looking for students with a fascination for science and innovation interested in sleep research.

(Last updated: 2025-04-30)