Mukai Jun
- Affiliation
- University of Tsukuba
- Official title
- Professor
- Research fields
General physiology - Research keywords
Precision medicine Neuroscience, Psychiatry, 22q11.2 deletion syndrome, schizophrenia, Autism, Neurodevelopmental disease, Histone methylation - Research projects
精神疾患の認知機能障害に対する早期治療法創出に向けた病的神経回路形成機構の解明 2022 -- (current) 向井 淳 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 統合失調症におけるヒストンメチルトランスフェラーゼSETD1Aの役割の解明 2019 -- 2021 向井 淳 Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(B) 17,420,000Yen - Career history
2018-07 -- (current) University of TsukubaResearch and Development Center for Precision MedicineProfessor - Degree
1995-03 医学博士 三重大学 - Articles
- Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a(+/-) Mice
Hamm Jordan P.; Shymkiv Yuriy; Mukai Jun; Gogos Joseph A...
Biological Psychiatry in Press (https://www.biologicalpsychiatryjournal.com/article/S0006-3223(20)30009-3/fulltext)/88(3)/pp.215-223, 2020-08 - Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice.
向井 淳; Cannavo E.; Sun Z.; Crabtree G.; Diamantopoulou A....
Neuron/104(3)/pp.471-487, 2019 - Loss-of-function mutation in rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion
Diamantopoulou Anastasia; Sun Ziyi; Mukai Jun; Xu Bin...
Proceedings of the National Academy of Sciences of the United States of America/114(30)/p.E6127-E6136, 2017-04 - Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition
Tamura Makoto; Mukai Jun; Gordon Joshua A; Gogos Jose...
Neuron/89(5)/pp.1100-1109, 2016-03 - Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome
Piskorowski Rebecca A; Nasrallah Kaoutsar; Diamantopoul...
Neuron/89(1)/pp.163-176, 2016-01 - Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia
Mukai Jun; Tamura Makoto; Fénelon Karine; Rosen Andre...
Neuron/86(3)/pp.680-695, 2015-05 - S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95
Ho Gary P H; Selvakumar Balakrishnan; Mukai Jun; Heste...
Neuron/71(1)/pp.131-141, 2011-07 - Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex
Fénelon Karine; Mukai Jun; Xu Bin; Hsu Pei-Ken; Drew ...
Proceedings of the National Academy of Sciences of the United States of America/108(11)/pp.4447-4452, 2011-03 - Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion
Mukai Jun; Dhilla Alefiya; Drew Liam J; Stark Kimberl...
Nature neuroscience/11(11)/pp.1302-1310, 2008-11 - Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
Paterlini Marta; Zakharenko Stanislav S; Lai Wen-Sung; ...
Nature neuroscience/8(11)/pp.1586-1594, 2005-11 - Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia
Mukai Jun; Liu Hui; Burt Rachel A; Swor Dionne E; Lai...
Nature genetics/36(7)/pp.725-731, 2004-07
- Aberrant Cortical Ensembles and Schizophrenia-like Sensory Phenotypes in Setd1a(+/-) Mice
(Last updated: 2020-01-23)