Louphrasitthiphol Pakavarin

Affiliation

Institute of Medicine

Official title

Assistant Professor

Research projects

膵がん幹細胞と微小環境の相互作用を担うMiTを断ち切る新規治療法の開発	2021 -- 2022	LOUPHRASITTHIPHOL PAKAVARIN	Japan Society for the Promotion of Science/Grant-in-Aid for Early-Career Scientists	4,680,000Yen

Articles

• DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition
  Louphrasitthiphol Pakavarin
  bioRxiv, 2023-04
• Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition
  Louphrasitthiphol Pakavarin
  bioRxiv, 2023-03
• Novel positron emission tomography imaging targeting cell surface glycans for pancreatic cancer: ¹⁸ F-labeled rBC2LCN lectin
  Kuroda Yukihito; Oda Tatsuya; Shimomura Osamu; Louphrasit...
  Cancer science, 2023-05-19
  
  PubMed
• Lectin-based phototherapy targeting cell surface glycans for pancreatic cancer
  Kuroda Yukihito; Oda Tatsuya; Shimomura Osamu; Hashimo...
  INTERNATIONAL JOURNAL OF CANCER/152(7)/pp.1425-1437, 2022-11-22
  
  PubMed
• Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy
  Yang Yu; Akashi Yoshimasa; Shimomura Osamu; Tateno Hiroa...
  GASTRIC CANCER/25(5)/pp.896-905, 2022-06-17
  
  PubMed
• TBX2 controls a proproliferative gene expression program in melanoma
  Lu Sizhu; Louphrasitthiphol Pakavarin; Goradia Nishit; ...
  GENES & DEVELOPMENT/35(23-24)/pp.1657-1677, 2021-12
• ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation
  Louphrasitthiphol Pakavarin; Chauhan Jagat; Goding Colin R
  Pigment cell & melanoma research/33(1)/pp.112-118, 2020-04
  
  PubMed
• BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma
  Herbert Katharine; Binet Romuald; Lambert Jean-Philipp...
  Genes & development/33(5-6)/pp.310-332, 2019-04
  
  PubMed
• ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes
  Neal Alice; Nornes Svanhild; Louphrasitthiphol Pakavar...
  Developmental biology/473/pp.1-14, 2021-05
  
  PubMed
• The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
  Coe Elizabeth A; Tan Jennifer Y; Shapiro Michael; Loup...
  PLoS genetics/15(12), 2019-04
  
  PubMed
• MITF controls the TCA cycle to modulate the melanoma hypoxia response
  Louphrasitthiphol Pakavarin; Ledaki Ioanna; Chauhan Ja...
  Pigment cell & melanoma research/32(6)/pp.792-808, 2019-04
  
  PubMed
• Venous identity requires BMP signalling through ALK3
  Neal Alice; Nornes Svanhild; Payne Sophie; Wallace Ma...
  Nature communications/10(1)/p.453, 2019-04
  
  PubMed
• Macrophage Cytoplasmic Transfer in Melanoma Invasion
  Louphrasitthiphol Pakavarin; Goding Colin R
  Developmental cell/43(5)/pp.543-544, 2017-04
  
  PubMed
• Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
  Vivas-García Yurena; Falletta Paola; Liebing Jana; Louphr...
  Molecular cell/77(1)/p.120-137.e9, 2020-04
  
  PubMed
• Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
  Louphrasitthiphol Pakavarin; Siddaway Robert; Loffreda A...
  Molecular cell/79(3)/p.472-487.e10, 2020-04
  
  PubMed

Conference, etc.

• Acetylation reprograms MITF target selectivity
  Louphrasitthiphol Pakavarin
  The 19th International Congress of the Society for Melanoma Research/2022-10-17--2022-10-20
• Isorhamnetin restricts cancer-associated fibroblasts (CAFs) phenotypic plasticity, poising them towards tumour-restraining myCAFs. Potential use of isorhamnetin as neoadjuvant in pancreatic ductal adenocarcinoma (PDAC)
  Ganbold Munkhzul; Louphrasitthiphol Pakavarin; Yoshinor...
  AACR Special Conference: Pancreatic Cancer/2022-09-13--2022-09-16

(Last updated: 2023-08-21)