Sugai Hiroka

Affiliation

Faculty of Pure and Applied Sciences

Official title

Assistant Professor

ORCID

0000-0002-5957-0011

KAKEN ID

10905566

Email

Research fields


Bio-related chemistry
Analytical chemistry

Research keywords


peptides
proteins
nucleic acids
biomacromolecules
biosensors

Research projects


短鎖ペプチドによるタンパク質不溶化の理解と精製技術への応用	2022-04 -- 2025-03	菅井祥加	筑波大学/科研費若手研究	4,550,000Yen
タンパク質集合体制御タグに関する探索的研究	2021-10 -- 2022-03	菅井祥加	筑波大学/科学技術振興機構さきがけ特定課題調査
タンパク質液滴の特徴パターンを捉える蛍光色素修飾ペプチド群の開発	2021-08 -- 2022-03	菅井祥加	筑波大学/科研費研究活動スタート支援	3,120,000Yen
安全性の高いがん細胞選択的核酸医薬システムの創成	2016-04 -- 2018-03	Hiroka Sugai	Tohoku University/Grant-in-Aid for JSPS Fellows	1,300,000Yen

Career history


2021-03 -- (current)	University of TsukubaFaculty of Pure and Applied SciencesAssistant Professor
2020-04 -- 2021-02	National Institute of Advanced Industrial Science and TechnologyHealth and Medical Research InstitutePostdoctoral Fellow
2018-04 -- 2020-03	National Institute of Advanced Industrial Science and TechnologyBiomedical Research InstitutePostdoctoral Fellow
2016-04 -- 2018-03	Japan Society for Promotion of ScienceResearch Fellow

Academic background


2015-04 -- 2018-03	Tohoku University Graduate School of Science Department of Chemistry
2013-04 -- 2015-03	Tohoku University Graduate School of Science Department of Chemistry
2009-04 -- 2013-03	Tohoku University Faculty of Science Department of Chemistry

Degree


2018-03	Doctor of Science	Tohoku University

Academic societies


-- (current)	THE CHEMICAL SOCIETY OF JAPAN
-- (current)	THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY

Honors & Awards


2021-02	若手特別賞	SATテクノロジー・ショーケース2021
2019-11	優秀ポスター賞	第14回ナノ・バイオメディカル学会

Articles

Uncharged Components of Single-Stranded DNA Modulate Liquid–Liquid Phase Separation With Cationic Linker Histone H1
Mimura Masahiro; Tomita Shunsuke; Sugai Hiroka; Shinkai ...
Frontiers in Cell and Developmental Biology/9/p.710729, 2021-08
分子アレイデバイスと多変量解析による生体試料評価
冨田峻介; 菅井祥加; 南木創; 栗田僚二
電気化学/88(3)/pp.262-271, 2020-09
生体試料の特徴情報を出力する交差反応性ポリマーアレイを利用したバイオメトリクス
菅井祥加; 冨田峻介; 栗田僚二
ケミカルエンジニヤリング/63(11)/pp.58-65, 2018-11
A biomimetic sensor array based on a single fluorescent block-copolymer for the pattern recognition of proteins
Tomita Shunsuke; Sugai Hiroka; Ishihara Sayaka; Hosokai ...
Chemistry Letters/49(12)/pp.1447-1451, 2020-12
Microfluidic sensing system with a multichannel surface plasmon resonance chip: Damage-free characterization of cells by pattern recognition
Sugai Hiroka; Tomita Shunsuke; Ishihara Sayaka; Yoshioka ...
Analytical Chemistry/92(22)/pp.14939-14946, 2020-10
PubMed
A multichannel pattern-recognition-based protein sensor with a fluorophore-conjugated single-stranded DNA set
Okada Mari; Sugai Hiroka; Tomita Shunsuke; Kurita Ryoji
Sensors/20(18)/p.5110, 2020-09
Optical Fingerprints of Proteases and Their Inhibited Complexes Provided by Differential Cross-Reactivity of Fluorophore-Labeled Single-Stranded DNA
Tomita Shunsuke; Sugai Hiroka; Mimura Masahiro; Ishihara ...
ACS applied materials & interfaces/11(50)/pp.47428-47436, 2019-12
PubMed
Pattern-recognition-based sensor arrays for cell characterization: From materials and data analyses to biomedical applications
Sugai Hiroka; Tomita Shunsuke; Kurita Ryoji
Analytical Sciences/36(8)/pp.923-934, 2020-08
One-component array based on a dansyl-modified polylysine: Generation of differential fluorescent signatures for the discrimination human cells
Sugai Hiroka; Tomita Shunsuke; Ishihara Sayaka; Kurita R...
ACS sensors/4(4)/pp.827-831, 2019-04
Fingerprint-based protein identification in cell culture medium using environment-sensitive turn-on fluorescent polymer
Sugai Hiroka; Tomita Shunsuke; Ishihara Sayaka; Kurita R...
Sensors and Materials/31(1)/pp.1-11, 2019-01
Peptide ribonucleic acid (PRNA)-arginine hybrids. Effects of arginine residues alternatingly introduced to PRNA backbone on aggregation, cellular uptake, and cytotoxicity
Sugai Hiroka; Nakase Ikuhiko; Sakamoto Seiji; Nishio Aki...
Chemistry Letters/47(3)/pp.381-384, 2018-03
Module strategy for peptide ribonucleic acid (PRNA)-DNA and PRNA-peptide nucleic acid (PNA)-DNA Chimeras. Synthesis and interaction of chimeras with DNA and RNA
Uematsu Ryohei; Inagaki Masahito; Asai Mitsuo; Sugai Hir...
Chemistry Letters/45(3)/pp.350-352, 2016-03

Books

特徴パターンの認識
菅井祥加; 冨田峻介
相分離生物学の全貌/東京化学同人/pp.343-348, 2020-11

Conference, etc.

蛍光団修飾ポリリジンを用いたパターン認識に基づく培養細胞の非破壊的評価
菅井祥加; 冨田峻介; 石原紗綾夏; 栗田僚二
日本分析化学会第70年会/2022-09
パターン認識に基づいて細胞を評価するセンサチップの開発
菅井祥加
SATテクノロジー・ショーケース2021/2021-02-19--2021-02-19
表面プラズモン共鳴の応答パターンを出力可能なマイクロ流体デバイスによる細胞評価
菅井祥加; 冨田峻介; 石原紗綾夏; 吉岡恭子; 栗田僚二
シンポジウム：細胞アッセイ技術の現状と将来/2021-01-26--2021-01-26
表面プラズモン共鳴の特徴パターンを出力するマルチチャネル型チップによる培養細胞の非破壊的評価
菅井祥加; 冨田峻介; 石原紗綾夏; 吉岡恭子; 栗田僚二
第80回分析化学討論会/2020-05-23--2020-05-24

Teaching


2022-04 -- 2022-06	ファーストイヤーセミナー	総合学域群
2022-04 -- 2022-05	学問への誘い	総合学域群

(Last updated: 2022-06-14)